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Items: 1 to 50 of 67

1.

The Bacillus anthracis protein MprF is required for synthesis of lysylphosphatidylglycerols and for resistance to cationic antimicrobial peptides.

Samant S, Hsu FF, Neyfakh AA, Lee H.

J Bacteriol. 2009 Feb;191(4):1311-9. doi: 10.1128/JB.01345-08. Epub 2008 Dec 12.

2.

Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion.

Newberry KJ, Huffman JL, Miller MC, Vazquez-Laslop N, Neyfakh AA, Brennan RG.

J Biol Chem. 2008 Sep 26;283(39):26795-804. doi: 10.1074/jbc.M804191200. Epub 2008 Jul 25.

3.

Nucleotide biosynthesis is critical for growth of bacteria in human blood.

Samant S, Lee H, Ghassemi M, Chen J, Cook JL, Mankin AS, Neyfakh AA.

PLoS Pathog. 2008 Feb 8;4(2):e37. doi: 10.1371/journal.ppat.0040037.

4.

Monitoring of gene knockouts: genome-wide profiling of conditionally essential genes.

Smith LK, Gomez MJ, Shatalin KY, Lee H, Neyfakh AA.

Genome Biol. 2007;8(5):R87.

5.

Genes involved in intrinsic antibiotic resistance of Acinetobacter baylyi.

Gomez MJ, Neyfakh AA.

Antimicrob Agents Chemother. 2006 Nov;50(11):3562-7. Epub 2006 Aug 28.

6.

A system for studying evolution of life-like virtual organisms.

Neyfakh AA, Baranova NN, Mizrokhi LJ.

Biol Direct. 2006 Aug 17;1:23.

7.
8.

Efficient gene inactivation in Bacillus anthracis.

Shatalin KY, Neyfakh AA.

FEMS Microbiol Lett. 2005 Apr 15;245(2):315-9.

9.

Collection and characterisation of bacterial membrane proteins.

Saidijam M, Psakis G, Clough JL, Meuller J, Suzuki S, Hoyle CJ, Palmer SL, Morrison SM, Pos MK, Essenberg RC, Maiden MC, Abu-bakr A, Baumberg SG, Neyfakh AA, Griffith JK, Stark MJ, Ward A, O'Reilly J, Rutherford NG, Phillips-Jones MK, Henderson PJ.

FEBS Lett. 2003 Nov 27;555(1):170-5.

10.

Isolation of antibiotic hypersusceptibility mutants of Acinetobacter spp. by selection for DNA release.

Lee H, Vázquez-Laslop N, Klyachko KA, Neyfakh AA.

Antimicrob Agents Chemother. 2003 Apr;47(4):1267-74.

11.

Mystery of multidrug transporters: the answer can be simple.

Neyfakh AA.

Mol Microbiol. 2002 Jun;44(5):1123-30. Review.

12.

Efflux-mediated drug resistance in Gram-positive bacteria.

Markham PN, Neyfakh AA.

Curr Opin Microbiol. 2001 Oct;4(5):509-14. Review.

PMID:
11587925
13.

Crystal structure of MtaN, a global multidrug transporter gene activator.

Godsey MH, Baranova NN, Neyfakh AA, Brennan RG.

J Biol Chem. 2001 Dec 14;276(50):47178-84. Epub 2001 Oct 1.

14.

The ostensible paradox of multidrug recognition.

Neyfakh AA.

J Mol Microbiol Biotechnol. 2001 Apr;3(2):151-4. Review.

PMID:
11321567
15.

Molecular sieve mechanism of selective release of cytoplasmic proteins by osmotically shocked Escherichia coli.

Vázquez-Laslop N, Lee H, Hu R, Neyfakh AA.

J Bacteriol. 2001 Apr;183(8):2399-404.

16.

Crystallization and preliminary X-ray diffraction studies on the DNA-binding domain of the multidrug transporter activation protein (MtaN) from Bacillus subtilis.

Godsey MH, Baranova NN, Neyfakh AA, Brennan RG.

Acta Crystallogr D Biol Crystallogr. 2000 Nov;56(Pt 11):1456-8.

PMID:
11053850
17.

Recognition of multiple drugs by a single protein: a trivial solution of an old paradox.

Vazquez-Laslop N, Zheleznova EE, Markham PN, Brennan RG, Neyfakh AA.

Biochem Soc Trans. 2000;28(4):517-20. Review.

PMID:
10961951
18.

A structure-based mechanism for drug binding by multidrug transporters.

Zheleznova EE, Markham P, Edgar R, Bibi E, Neyfakh AA, Brennan RG.

Trends Biochem Sci. 2000 Feb;25(2):39-43. Review.

PMID:
10664577
19.
20.

Multiple novel inhibitors of the NorA multidrug transporter of Staphylococcus aureus.

Markham PN, Westhaus E, Klyachko K, Johnson ME, Neyfakh AA.

Antimicrob Agents Chemother. 1999 Oct;43(10):2404-8.

21.

Mta, a global MerR-type regulator of the Bacillus subtilis multidrug-efflux transporters.

Baranova NN, Danchin A, Neyfakh AA.

Mol Microbiol. 1999 Mar;31(5):1549-59.

22.

Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.

Zheleznova EE, Markham PN, Neyfakh AA, Brennan RG.

Cell. 1999 Feb 5;96(3):353-62.

24.
25.

Broad ligand specificity of the transcriptional regulator of the Bacillus subtilis multidrug transporter Bmr.

Markham PN, LoGuidice J, Neyfakh AA.

Biochem Biophys Res Commun. 1997 Oct 9;239(1):269-72.

PMID:
9345308
26.

Natural functions of bacterial multidrug transporters.

Neyfakh AA.

Trends Microbiol. 1997 Aug;5(8):309-13. Review.

PMID:
9263408
27.
28.

Efflux of the natural polyamine spermidine facilitated by the Bacillus subtilis multidrug transporter Blt.

Woolridge DP, Vazquez-Laslop N, Markham PN, Chevalier MS, Gerner EW, Neyfakh AA.

J Biol Chem. 1997 Apr 4;272(14):8864-6.

29.

Mutations affecting substrate specificity of the Bacillus subtilis multidrug transporter Bmr.

Klyachko KA, Schuldiner S, Neyfakh AA.

J Bacteriol. 1997 Apr;179(7):2189-93.

30.

Inhibition of the multidrug transporter NorA prevents emergence of norfloxacin resistance in Staphylococcus aureus.

Markham PN, Neyfakh AA.

Antimicrob Agents Chemother. 1996 Nov;40(11):2673-4. No abstract available.

31.
32.

Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated.

Ahmed M, Lyass L, Markham PN, Taylor SS, Vázquez-Laslop N, Neyfakh AA.

J Bacteriol. 1995 Jul;177(14):3904-10.

33.

A protein that activates expression of a multidrug efflux transporter upon binding the transporter substrates.

Ahmed M, Borsch CM, Taylor SS, Vázquez-Laslop N, Neyfakh AA.

J Biol Chem. 1994 Nov 11;269(45):28506-13.

34.

GENETIC CONTROL OF THE RATE OF EMBRYONIC DEVELOPMENT: SELECTION FOR FASTER DEVELOPMENT AT ELEVATED TEMPERATURES.

Neyfakh AA, Hartl DL.

Evolution. 1993 Oct;47(5):1625-1631. doi: 10.1111/j.1558-5646.1993.tb02182.x. No abstract available. Erratum in: Evolution. 1996 Feb;50(1):475.

PMID:
28564900
35.
36.

Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter.

Neyfakh AA, Borsch CM, Kaatz GW.

Antimicrob Agents Chemother. 1993 Jan;37(1):128-9.

38.
39.

Multidrug-resistance phenotype of a subpopulation of T-lymphocytes without drug selection.

Neyfakh AA, Serpinskaya AS, Chervonsky AV, Apasov SG, Kazarov AR.

Exp Cell Res. 1989 Dec;185(2):496-505.

PMID:
2480910
40.

The membrane transport system responsible for multidrug resistance is operating in nonresistant cells.

Neyfakh AA, Dmitrevskaya TV, Serpinskaya AS.

Exp Cell Res. 1988 Oct;178(2):513-7.

PMID:
3169137
41.
42.

Actin cytoskeleton of spread fibroblasts appears to assemble at the cell edges.

Svitkina TM, Neyfakh AA Jr, Bershadsky AD.

J Cell Sci. 1986 Jun;82:235-48.

43.

Focal contacts of normal and RSV-transformed quail cells. Hypothesis of the transformation-induced deficient maturation of focal contacts.

Bershadsky AD, Tint IS, Neyfakh AA Jr, Vasiliev JM.

Exp Cell Res. 1985 Jun;158(2):433-44.

PMID:
2988988
44.

Lipid-cell interactions. Liposome adsorption and cell-to-liposome lipid transfer are mediated by the same cell-surface sites.

Margolis LB, Baibakov BA, Neyfakh AA Jr, Victorov AV, Galkina SI, Bergelson LD.

Biochim Biophys Acta. 1984 May 22;804(1):23-30.

PMID:
6722182
46.

Isolation of focal contact membrane using saponin.

Neyfakh AA Jr, Svitkina TM.

Exp Cell Res. 1983 Dec;149(2):582-6.

PMID:
6641816
47.

Visualization of cellular focal contacts using a monoclonal antibody to 80 kD serum protein adsorbed on the substratum.

Neyfakh AA Jr, Tint IS, Svitkina TM, Bershadsky AD, Gelfand VI.

Exp Cell Res. 1983 Dec;149(2):387-96.

PMID:
6357815
48.

Liposomes inhibit intercellular attachment.

Margolis LB, Neyfakh AA Jr.

Exp Cell Res. 1983 Oct 15;148(2):536-40.

PMID:
6628569
49.

The distribution of solid liposomes of different size on the surface of epithelial cells.

Margolis LB, Neyfakh AA Jr.

Eur J Cell Biol. 1983 Sep;31(2):256-62.

PMID:
6641737
50.

Nonuniform distribution of enzymes in fish eggs.

Klyachko OS, Korzh VP, Gorgolyuk SI, Timofeev AV, Neyfakh AA.

J Exp Zool. 1982 Aug 10;222(2):137-48.

PMID:
7130926

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