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Vitamin B<sub>12</sub> deficiency. Green R et al. Nat Rev Dis Primers. (2017)

Unexpected high plasma cobalamin : proposal for a diagnostic strategy. Arendt JF et al. Clin Chem Lab Med. (2013)

Cobalamin coenzyme forms are not likely to be superior to cyano- and hydroxyl-cobalamin in prevention or treatment of cobalamin deficiency. Obeid R et al. Mol Nutr Food Res. (2015)

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Items: 1 to 50 of 404


Systemically Administered Plant Recombinant Holo-Intrinsic Factor Targets the Liver and is not Affected by Endogenous B12 levels.

Workinger JL, Kuda-Wedagedara ANW, Julin MM, White JM, Nexo E, Viola NT, Doyle RP.

Sci Rep. 2019 Aug 22;9(1):12269. doi: 10.1038/s41598-019-48555-w.


Vitamin B12 and its binding proteins in milk from cow and buffalo in relation to bioavailability of B12.

Fedosov SN, Nexo E, Heegaard CW.

J Dairy Sci. 2019 Jun;102(6):4891-4905. doi: 10.3168/jds.2018-15016. Epub 2019 Mar 28.


Comparative Bioavailability of Synthetic B12 and Dietary Vitamin B12 Present in Cow and Buffalo Milk: A Prospective Study in Lactovegetarian Indians.

Mahalle N, Bhide V, Greibe E, Heegaard CW, Nexo E, Fedosov SN, Naik S.

Nutrients. 2019 Feb 1;11(2). pii: E304. doi: 10.3390/nu11020304.


Kinetic analysis of transcellular passage of the cobalamin-transcobalamin complex in Caco-2 monolayers.

Juul CB, Fedosov SN, Nexo E, Heegaard CW.

Mol Biol Cell. 2019 Feb 15;30(4):467-477. doi: 10.1091/mbc.E18-09-0571. Epub 2018 Dec 19.


Nutritional 1C Imbalance, B12 Tissue Accumulation, and Pregnancy Outcomes: An Experimental Study in Rats.

Nymark O, Nexo E, Greibe E.

Nutrients. 2018 Oct 26;10(11). pii: E1579. doi: 10.3390/nu10111579.


Differences in Tissue Distribution of Cyano⁻B12 and Hydroxo⁻B12 One Week after Oral Intake: An Experimental Study in Male Wistar Rats.

Greibe E, Nymark O, Fedosov SN, Heegaard CW, Nexo E.

Nutrients. 2018 Oct 12;10(10). pii: E1487. doi: 10.3390/nu10101487.


Does a Conjugation Site Affect Transport of Vitamin B12 -Peptide Nucleic Acid Conjugates into Bacterial Cells?

Wierzba AJ, Maximova K, Wincenciuk A, Równicki M, Wojciechowska M, Nexø E, Trylska J, Gryko D.

Chemistry. 2018 Dec 12;24(70):18772-18778. doi: 10.1002/chem.201804304. Epub 2018 Nov 15.


Gastrointestinal Handling of Water-Soluble Vitamins.

Said HM, Nexo E.

Compr Physiol. 2018 Sep 14;8(4):1291-1311. doi: 10.1002/cphy.c170054. Review.


Dietary Intake of Vitamin B12 is Better for Restoring a Low B12 Status Than a Daily High-Dose Vitamin Pill: An Experimental Study in Rats.

Greibe E, Nymark O, Fedosov SN, Heegaard CW, Nexo E.

Nutrients. 2018 Aug 15;10(8). pii: E1096. doi: 10.3390/nu10081096.


The tissue profile of metabolically active coenzyme forms of vitamin B12 differs in vitamin B12-depleted rats treated with hydroxo-B12 or cyano-B12.

Greibe E, Kornerup LS, Juul CB, Fedosov SN, Heegaard CW, Nexo E.

Br J Nutr. 2018 Jul;120(1):49-56. doi: 10.1017/S000711451800123X.


Early changes in vitamin B12 uptake and biomarker status following Roux-en-Y gastric bypass and sleeve gastrectomy.

Kornerup LS, Hvas CL, Abild CB, Richelsen B, Nexo E.

Clin Nutr. 2019 Apr;38(2):906-911. doi: 10.1016/j.clnu.2018.02.007. Epub 2018 Feb 15.


Soluble HER3 predicts survival in bladder cancer patients.

Memon AA, Gilliver SC, Borre M, Sundquist J, Sundquist K, Nexo E, Sorensen BS.

Oncol Lett. 2018 Feb;15(2):1783-1788. doi: 10.3892/ol.2017.7470. Epub 2017 Nov 22.


Effect of 8-week oral supplementation with 3-µg cyano-B12 or hydroxo-B12 in a vitamin B12-deficient population.

Greibe E, Mahalle N, Bhide V, Fedosov S, Heegaard CW, Naik S, Nexo E.

Eur J Nutr. 2019 Feb;58(1):261-270. doi: 10.1007/s00394-017-1590-0. Epub 2017 Dec 5.


89Zr-Cobalamin PET Tracer: Synthesis, Cellular Uptake, and Use for Tumor Imaging.

Kuda-Wedagedara ANW, Workinger JL, Nexo E, Doyle RP, Viola-Villegas N.

ACS Omega. 2017 Oct 31;2(10):6314-6320. doi: 10.1021/acsomega.7b01180. Epub 2017 Oct 2.


Increase in circulating holotranscobalamin after oral administration of cyanocobalamin or hydroxocobalamin in healthy adults with low and normal cobalamin status.

Greibe E, Mahalle N, Bhide V, Heegaard CW, Naik S, Nexo E.

Eur J Nutr. 2018 Dec;57(8):2847-2855. doi: 10.1007/s00394-017-1553-5. Epub 2017 Oct 16.


Organometallic DNA-B12 Conjugates as Potential Oligonucleotide Vectors: Synthesis and Structural and Binding Studies with Human Cobalamin-Transport Proteins.

Mutti E, Hunger M, Fedosov S, Nexo E, Kräutler B.

Chembiochem. 2017 Nov 16;18(22):2280-2291. doi: 10.1002/cbic.201700472. Epub 2017 Oct 10.


Correction: Vitamin B12 deficiency.

Green R, Allen LH, Bjørke-Monsen AL, Brito A, Guéant JL, Miller JW, Molloy AM, Nexo E, Stabler S, Toh BH, Ueland PM, Yajnik C.

Nat Rev Dis Primers. 2017 Jul 20;3:17054. doi: 10.1038/nrdp.2017.54.


Vitamin B12 deficiency.

Green R, Allen LH, Bjørke-Monsen AL, Brito A, Guéant JL, Miller JW, Molloy AM, Nexo E, Stabler S, Toh BH, Ueland PM, Yajnik C.

Nat Rev Dis Primers. 2017 Jun 29;3:17040. doi: 10.1038/nrdp.2017.40. Review. Erratum in: Nat Rev Dis Primers. 2017 Jul 20;3:17054.


Long-term Outcome of 4 Patients With Transcobalamin Deficiency Caused by 2 Novel TCN2 Mutations.

Nashabat M, Maegawa G, Nissen PH, Nexo E, Al-Shamrani H, Al-Owain M, Alfadhel M.

J Pediatr Hematol Oncol. 2017 Nov;39(8):e430-e436. doi: 10.1097/MPH.0000000000000857.


The soluble transcobalamin receptor (sCD320) in relation to Alzheimer's disease and cognitive scores.

Abuyaman O, Combrinck M, Smith AD, Nexo E.

Scand J Clin Lab Invest. 2017 Sep;77(5):332-337. doi: 10.1080/00365513.2017.1323345. Epub 2017 May 9.


Tissue distribution of oral vitamin B12 is influenced by B12 status and B12 form: an experimental study in rats.

Kornerup LS, Fedosov SN, Juul CB, Greibe E, Heegaard CW, Nexo E.

Eur J Nutr. 2018 Jun;57(4):1459-1469. doi: 10.1007/s00394-017-1424-0. Epub 2017 Mar 20.


Testosterone Measured with an Automatic Immunoassay Compares Reasonably Well to Results Obtained by LC-MS/MS.

Knudsen CS, Hoejskov CS, Moller HJ, Nexo E.

Clin Lab. 2016 Oct 1;62(10):2039-2043. doi: 10.7754/Clin.Lab.2016.160143.


Forms and Amounts of Vitamin B12 in Infant Formula: A Pilot Study.

Greibe E, Nexo E.

PLoS One. 2016 Nov 16;11(11):e0165458. doi: 10.1371/journal.pone.0165458. eCollection 2016.


Seven Patients With Transcobalamin Deficiency Diagnosed Between 2010 and 2014: A Single-Center Experience.

Yildirim ZK, Nexo E, Rupar T, Büyükavci M.

J Pediatr Hematol Oncol. 2017 Jan;39(1):38-41.


Trefoil factor peptide 3 is positively correlated with the viscoelastic properties of the cervical mucus plug.

Bastholm SK, Samson MH, Becher N, Hansen LK, Stubbe PR, Chronakis IS, Nexo E, Uldbjerg N.

Acta Obstet Gynecol Scand. 2017 Jan;96(1):47-52. doi: 10.1111/aogs.13038. Epub 2016 Nov 25.


First trimester serum levels of the soluble transcobalamin receptor, holo-transcobalamin, and total transcobalamin in relation to preeclampsia risk.

Abuyaman O, Torring N, Obeid R, Nexo E.

Scand J Clin Lab Invest. 2016 Dec;76(8):641-644. Epub 2016 Oct 4.


False low holotranscobalamin levels in a patient with a novel TCN2 mutation.

Keller P, Rufener J, Schild C, Fedosov SN, Nissen PH, Nexo E.

Clin Chem Lab Med. 2016 Nov 1;54(11):1739-1743. doi: 10.1515/cclm-2016-0063.


Vitamin B12 Phosphate Conjugation and Its Effect on Binding to the Human B12 -Binding Proteins Intrinsic Factor and Haptocorrin.

Ó Proinsias K, Ociepa M, Pluta K, Chromiński M, Nexo E, Gryko D.

Chemistry. 2016 Jun 6;22(24):8282-9. doi: 10.1002/chem.201504898. Epub 2016 Apr 27.


Elevated plasma vitamin B12 levels and cancer prognosis: A population-based cohort study.

Arendt JF, Farkas DK, Pedersen L, Nexo E, Sørensen HT.

Cancer Epidemiol. 2016 Feb;40:158-65. doi: 10.1016/j.canep.2015.12.007. Epub 2015 Dec 24.


Absorption and retention of free and milk protein-bound cyano- and hydroxocobalamins. An experimental study in rats.

Kornerup LS, Juul CB, Fedosov SN, Heegaard CW, Greibe E, Nexo E.

Biochimie. 2016 Jul;126:57-62. doi: 10.1016/j.biochi.2015.11.024. Epub 2015 Nov 25.


The soluble transcobalamin receptor (sCD320) is present in cerebrospinal fluid and correlates to dementia-related biomarkers tau proteins and amyloid-beta.

Abuyaman O, Nexo E.

Scand J Clin Lab Invest. 2015 Oct;75(6):514-8. doi: 10.3109/00365513.2015.1057761. Epub 2015 Jul 24.


Cobalamin coenzyme forms are not likely to be superior to cyano- and hydroxyl-cobalamin in prevention or treatment of cobalamin deficiency.

Obeid R, Fedosov SN, Nexo E.

Mol Nutr Food Res. 2015 Jul;59(7):1364-72. doi: 10.1002/mnfr.201500019. Epub 2015 May 12. Review.


Salivary acetylcholinesterase activity is increased in Parkinson's disease: a potential marker of parasympathetic dysfunction.

Fedorova T, Knudsen CS, Mouridsen K, Nexo E, Borghammer P.

Parkinsons Dis. 2015;2015:156479. doi: 10.1155/2015/156479. Epub 2015 Feb 12.


Trefoil factors (TFFs) are increased in bronchioalveolar lavage fluid from patients with chronic obstructive lung disease (COPD).

Viby NE, Nexø E, Kissow H, Andreassen H, Clementsen P, Thim L, Poulsen SS.

Peptides. 2015 Jan;63:90-5. doi: 10.1016/j.peptides.2014.09.026. Epub 2014 Oct 23.


Organometallic B12-DNA conjugate: synthesis, structure analysis, and studies of binding to human B12-transporter proteins.

Hunger M, Mutti E, Rieder A, Enders B, Nexo E, Kräutler B.

Chemistry. 2014 Oct 6;20(41):13103-7. doi: 10.1002/chem.201404359. Epub 2014 Aug 28.


Stability of 35 biochemical and immunological routine tests after 10 hours storage and transport of human whole blood at 21°C.

Henriksen LO, Faber NR, Moller MF, Nexo E, Hansen AB.

Scand J Clin Lab Invest. 2014 Oct;74(7):603-10. doi: 10.3109/00365513.2014.928940. Epub 2014 Jul 2.


Vitamin B₁₂ and its binding proteins in hepatocellular carcinoma and chronic liver diseases.

Simonsen K, Rode A, Nicoll A, Villadsen G, Espelund U, Lim L, Angus P, Arachchi N, Vilstrup H, Nexo E, Grønbæk H.

Scand J Gastroenterol. 2014 Sep;49(9):1096-102. doi: 10.3109/00365521.2014.921325. Epub 2014 Jun 24.


Detection of EGFR mutations in plasma and biopsies from non-small cell lung cancer patients by allele-specific PCR assays.

Weber B, Meldgaard P, Hager H, Wu L, Wei W, Tsai J, Khalil A, Nexo E, Sorensen BS.

BMC Cancer. 2014 Apr 28;14:294. doi: 10.1186/1471-2407-14-294.


Trefoil factor peptides in serum and sputum from subjects with asthma and COPD.

Viby NE, Pedersen L, Lund TK, Kissow H, Backer V, Nexø E, Thim L, Poulsen SS.

Clin Respir J. 2015 Jul;9(3):322-9. doi: 10.1111/crj.12146. Epub 2014 Jun 16.


Co-expression of HER3 and MUC1 is associated with a favourable prognosis in patients with bladder cancer.

Nielsen TO, Borre M, Nexo E, Sorensen BS.

BJU Int. 2015 Jan;115(1):163-5. doi: 10.1111/bju.12658.


EGFR mutation frequency and effectiveness of erlotinib: a prospective observational study in Danish patients with non-small cell lung cancer.

Weber B, Hager H, Sorensen BS, McCulloch T, Mellemgaard A, Khalil AA, Nexo E, Meldgaard P.

Lung Cancer. 2014 Feb;83(2):224-30. doi: 10.1016/j.lungcan.2013.11.023. Epub 2013 Dec 4.


Tumor imaging in patients with advanced tumors using a new (99m) Tc-radiolabeled vitamin B12 derivative.

Sah BR, Schibli R, Waibel R, von Boehmer L, Bläuenstein P, Nexo E, Johayem A, Fischer E, Müller E, Soyka JD, Knuth AK, Haerle SK, Schubiger PA, Schaefer NG, Burger IA.

J Nucl Med. 2014 Jan;55(1):43-9. doi: 10.2967/jnumed.113.122499. Epub 2013 Dec 12.


Expression of the epidermal growth factor system in human middle ear cholesteatoma.

Thorup MB, Munk M, Poulsen SS, Gaihede M, Nexo E, Sorensen BS, Ovesen T.

Acta Otolaryngol. 2014 Feb;134(2):124-34. doi: 10.3109/00016489.2013.847282. Epub 2013 Nov 21.


Elevated plasma vitamin B12 levels as a marker for cancer: a population-based cohort study.

Arendt JF, Pedersen L, Nexo E, Sørensen HT.

J Natl Cancer Inst. 2013 Dec 4;105(23):1799-805. doi: 10.1093/jnci/djt315. Epub 2013 Nov 18.


A soluble form of the macrophage-related mannose receptor (MR/CD206) is present in human serum and elevated in critical illness.

Rødgaard-Hansen S, Rafique A, Christensen PA, Maniecki MB, Sandahl TD, Nexø E, Møller HJ.

Clin Chem Lab Med. 2014 Mar;52(3):453-61. doi: 10.1515/cclm-2013-0451.


Expression of PIK3CA, PTEN mRNA and PIK3CA mutations in primary breast cancer: association with lymph node metastases.

Palimaru I, Brügmann A, Wium-Andersen MK, Nexo E, Sorensen BS.

Springerplus. 2013 Sep 16;2:464. doi: 10.1186/2193-1801-2-464. eCollection 2013.


4-ethylphenyl-cobalamin impairs tissue uptake of vitamin B12 and causes vitamin B12 deficiency in mice.

Mutti E, Ruetz M, Birn H, Kräutler B, Nexo E.

PLoS One. 2013 Sep 20;8(9):e75312. doi: 10.1371/journal.pone.0075312. eCollection 2013.


The HER4 isoform JM-a/CYT2 relates to improved survival in bladder cancer patients but only if the estrogen receptor α is not expressed.

Munk M, Memon A, Poulsen SS, Borre M, Nexo E, Sorensen BS.

Scand J Clin Lab Invest. 2013 Sep;73(6):503-13. doi: 10.3109/00365513.2013.818706.


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