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Comparative performance of Cu-zeolites in the isothermal conversion of methane to methanol.

Knorpp AJ, Newton MA, Mizuno SCM, Zhu J, Mebrate H, Pinar AB, van Bokhoven JA.

Chem Commun (Camb). 2019 Oct 7;55(78):11794-11797. doi: 10.1039/c9cc05659a. Epub 2019 Sep 16.


Disordered Antigens and Epitope Overlap Between Anti-Citrullinated Protein Antibodies and Rheumatoid Factor in Rheumatoid Arthritis.

Zheng Z, Mergaert AM, Fahmy LM, Bawadekar M, Holmes CL, Ong IM, Bridges AJ, Newton MA, Shelef MA.

Arthritis Rheumatol. 2019 Aug 8. doi: 10.1002/art.41074. [Epub ahead of print]


Predicting kinase inhibitors using bioactivity matrix derived informer sets.

Zhang H, Ericksen SS, Lee CP, Ananiev GE, Wlodarchak N, Yu P, Mitchell JC, Gitter A, Wright SJ, Hoffmann FM, Wildman SA, Newton MA.

PLoS Comput Biol. 2019 Aug 5;15(8):e1006813. doi: 10.1371/journal.pcbi.1006813. eCollection 2019 Aug.


Melanoma Progression Inhibits Pluripotency and Differentiation of Melanoma-Derived iPSCs Produces Cells with Neural-like Mixed Dysplastic Phenotype.

Castro-Pérez E, Rodríguez CI, Mikheil D, Siddique S, McCarthy A, Newton MA, Setaluri V.

Stem Cell Reports. 2019 Jul 9;13(1):177-192. doi: 10.1016/j.stemcr.2019.05.018. Epub 2019 Jun 20.


Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation.

Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette AA, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, Clipson L, Walsh CM, Miller D, Carchman EH, Burkard ME, Lemmon KK, Matkowskyj KA, Newton MA, Ong IM, Bassetti MF, Kimple RJ, Skala MC, Deming DA.

Clin Cancer Res. 2019 Sep 1;25(17):5376-5387. doi: 10.1158/1078-0432.CCR-18-3590. Epub 2019 Jun 7.


Enrichment of melanoma-associated T cells in 6-thioguanine-resistant T cells from metastatic melanoma patients.

Zuleger CL, Newton MA, Ma X, Ong IM, Pei Q, Albertini MR.

Melanoma Res. 2019 May 23. doi: 10.1097/CMR.0000000000000625. [Epub ahead of print]


Monomeric Copper(II) Sites Supported on Alumina Selectively Convert Methane to Methanol.

Meyet J, Searles K, Newton MA, Wörle M, van Bavel AP, Horton AD, van Bokhoven JA, Copéret C.

Angew Chem Int Ed Engl. 2019 Jul 15;58(29):9841-9845. doi: 10.1002/anie.201903802. Epub 2019 Jun 7.


Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.

Mikheil DM, Prabhakar K, Arshad A, Rodriguez CI, Newton MA, Setaluri V.

Pigment Cell Melanoma Res. 2019 Jul;32(4):528-539. doi: 10.1111/pcmr.12764. Epub 2019 Feb 3.


MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers.

Fricke SL, Payne SN, Favreau PF, Kratz JD, Pasch CA, Foley TM, Yueh AE, Van De Hey DR, Depke MG, Korkos DP, Sha GC, DeStefanis RA, Clipson L, Burkard ME, Lemmon KK, Parsons BM, Kenny PA, Matkowskyj KA, Newton MA, Skala MC, Deming DA.

Mol Cancer Ther. 2019 Feb;18(2):346-355. doi: 10.1158/1535-7163.MCT-18-0510. Epub 2018 Nov 13.


The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer.

Pleiman JK, Irving AA, Wang Z, Toraason E, Clipson L, Dove WF, Deming DA, Newton MA.

PLoS Genet. 2018 Sep 6;14(9):e1007611. doi: 10.1371/journal.pgen.1007611. eCollection 2018 Sep.


On the Mechanism Underlying the Direct Conversion of Methane to Methanol by Copper Hosted in Zeolites; Braiding Cu K-Edge XANES and Reactivity Studies.

Newton MA, Knorpp AJ, Pinar AB, Sushkevich VL, Palagin D, van Bokhoven JA.

J Am Chem Soc. 2018 Aug 15;140(32):10090-10093. doi: 10.1021/jacs.8b05139. Epub 2018 Aug 6.


4-HPR Is an Endoplasmic Reticulum Stress Aggravator and Sensitizes Breast Cancer Cells Resistant to TRAIL/Apo2L.

Anding AL, Jones JD, Newton MA, Curley RW Jr, Clagett-Dame M.

Anticancer Res. 2018 Aug;38(8):4403-4416. doi: 10.21873/anticanres.12742.


RNA expression profiling in sulfamethoxazole-treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes.

Reinhart JM, Rose W, Panyard DJ, Newton MA, Liebenstein TK, Yee J, Trepanier LA.

Pharmacol Res Perspect. 2018 Mar 2;6(2):e00388. doi: 10.1002/prp2.388. eCollection 2018 Apr.


Pilot study of safety and feasibility of DNA microseeding for treatment of spontaneous canine melanoma.

Zuleger CL, Kang C, Ranheim EA, Kurzman ID, Macklin MD, Newton MA, Wolchok JD, Vail DM, Eriksson E, Albertini MR.

Vet Med Sci. 2017 May 22;3(3):134-145. doi: 10.1002/vms3.65. eCollection 2017 Aug.


Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening.

Ericksen SS, Wu H, Zhang H, Michael LA, Newton MA, Hoffmann FM, Wildman SA.

J Chem Inf Model. 2017 Jul 24;57(7):1579-1590. doi: 10.1021/acs.jcim.7b00153. Epub 2017 Jul 12.


Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics.

Barger JL, Vann JM, Cray NL, Pugh TD, Mastaloudis A, Hester SN, Wood SM, Newton MA, Weindruch R, Prolla TA.

Aging Cell. 2017 Aug;16(4):750-760. doi: 10.1111/acel.12608. Epub 2017 May 26.


Solvent-dependent nuclearity, geometry and catalytic activity of [(SPhos)Pd(Ph)Cl]2.

Brazier JB, Newton MA, Barreiro EM, Adrio LA, Naya L, Hii KKM.

Dalton Trans. 2017 Jun 6;46(22):7223-7231. doi: 10.1039/c7dt01019b.


Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations.

Foley TM, Payne SN, Pasch CA, Yueh AE, Van De Hey DR, Korkos DP, Clipson L, Maher ME, Matkowskyj KA, Newton MA, Deming DA.

Mol Cancer Res. 2017 Feb 9;15(3):317-327. doi: 10.1158/1541-7786.MCR-16-0256. [Epub ahead of print]


A statistical approach for identifying differential distributions in single-cell RNA-seq experiments.

Korthauer KD, Chu LF, Newton MA, Li Y, Thomson J, Stewart R, Kendziorski C.

Genome Biol. 2016 Oct 25;17(1):222.


Kinetic Studies of the Pt Carbonate-Mediated, Room-Temperature Oxidation of Carbon Monoxide by Oxygen over Pt/Al2O3 Using Combined, Time-Resolved XAFS, DRIFTS, and Mass Spectrometry.

Newton MA, Ferri D, Smolentsev G, Marchionni V, Nachtegaal M.

J Am Chem Soc. 2016 Oct 26;138(42):13930-13940. doi: 10.1021/jacs.6b06819. Epub 2016 Oct 17.


Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.

Sievers CK, Zou LS, Pickhardt PJ, Matkowskyj KA, Albrecht DM, Clipson L, Bacher JW, Pooler BD, Moawad FJ, Cash BD, Reichelderfer M, Vo TN, Newton MA, Larget BR, Halberg RB.

Gut. 2017 Dec;66(12):2132-2140. doi: 10.1136/gutjnl-2016-312232. Epub 2016 Sep 8.


Making the cut: improved ranking and selection for large-scale inference.

Henderson NC, Newton MA.

J R Stat Soc Series B Stat Methodol. 2016 Sep;78(4):781-804. Epub 2015 Nov 8.


Phase I study to evaluate toxicity and feasibility of intratumoral injection of α-gal glycolipids in patients with advanced melanoma.

Albertini MR, Ranheim EA, Zuleger CL, Sondel PM, Hank JA, Bridges A, Newton MA, McFarland T, Collins J, Clements E, Henry MB, Neuman HB, Weber S, Whalen G, Galili U.

Cancer Immunol Immunother. 2016 Aug;65(8):897-907. doi: 10.1007/s00262-016-1846-1. Epub 2016 May 20.


Correction: Dosage compensation can buffer copy-number variation in wild yeast.

Hose J, Yong CM, Sardi M, Wang Z, Newton MA, Gasch AP.

Elife. 2016 Mar 23;5. pii: e15743. doi: 10.7554/eLife.15743. No abstract available.


Heterochromatin Protein 1 Binding Protein 3 Expression as a Candidate Marker of Intrinsic 5-Fluorouracil Resistance.

Hadac JN, Miller DD, Grimes IC, Clipson L, Newton MA, Schelman WR, Halberg RB.

Anticancer Res. 2016 Mar;36(3):845-52.


Further support for aneuploidy tolerance in wild yeast and effects of dosage compensation on gene copy-number evolution.

Gasch AP, Hose J, Newton MA, Sardi M, Yong M, Wang Z.

Elife. 2016 Mar 7;5:e14409. doi: 10.7554/eLife.14409.


Advanced Intestinal Cancers often Maintain a Multi-Ancestral Architecture.

Zahm CD, Szulczewski JM, Leystra AA, Paul Olson TJ, Clipson L, Albrecht DM, Middlebrooks M, Thliveris AT, Matkowskyj KA, Washington MK, Newton MA, Eliceiri KW, Halberg RB.

PLoS One. 2016 Feb 26;11(2):e0150170. doi: 10.1371/journal.pone.0150170. eCollection 2016.


Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer.

Bodelon C, Vinokurova S, Sampson JN, den Boon JA, Walker JL, Horswill MA, Korthauer K, Schiffman M, Sherman ME, Zuna RE, Mitchell J, Zhang X, Boland JF, Chaturvedi AK, Dunn ST, Newton MA, Ahlquist P, Wang SS, Wentzensen N.

Carcinogenesis. 2016 Feb;37(2):188-196. doi: 10.1093/carcin/bgv171. Epub 2015 Dec 9. No abstract available.


X-ray spectroscopy for chemistry in the 2-4 keV energy regime at the XMaS beamline: ionic liquids, Rh and Pd catalysts in gas and liquid environments, and Cl contamination in γ-Al2O3.

Thompson PB, Nguyen BN, Nicholls R, Bourne RA, Brazier JB, Lovelock KR, Brown SD, Wermeille D, Bikondoa O, Lucas CA, Hase TP, Newton MA.

J Synchrotron Radiat. 2015 Nov;22(6):1426-39. doi: 10.1107/S1600577515016148. Epub 2015 Oct 1.


Room-temperature carbon monoxide oxidation by oxygen over Pt/Al2O3 mediated by reactive platinum carbonates.

Newton MA, Ferri D, Smolentsev G, Marchionni V, Nachtegaal M.

Nat Commun. 2015 Oct 22;6:8675. doi: 10.1038/ncomms9675.


Electronic structures of cyclometalated palladium complexes in the higher oxidation states.

Nguyen BN, Adrio LA, Albrecht T, White AJ, Newton MA, Nachtegaal M, Figueroa SJ, Hii KK.

Dalton Trans. 2015 Oct 7;44(37):16586-91. doi: 10.1039/c5dt02104a.


Single-molecule analysis reveals widespread structural variation in multiple myeloma.

Gupta A, Place M, Goldstein S, Sarkar D, Zhou S, Potamousis K, Kim J, Flanagan C, Li Y, Newton MA, Callander NS, Hematti P, Bresnick EH, Ma J, Asimakopoulos F, Schwartz DC.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7689-94. doi: 10.1073/pnas.1418577112. Epub 2015 Jun 8.


Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling.

den Boon JA, Pyeon D, Wang SS, Horswill M, Schiffman M, Sherman M, Zuna RE, Wang Z, Hewitt SM, Pearson R, Schott M, Chung L, He Q, Lambert P, Walker J, Newton MA, Wentzensen N, Ahlquist P.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3255-64. doi: 10.1073/pnas.1509322112. Epub 2015 Jun 8.


Dosage compensation can buffer copy-number variation in wild yeast.

Hose J, Yong CM, Sardi M, Wang Z, Newton MA, Gasch AP.

Elife. 2015 May 8;4. doi: 10.7554/eLife.05462. Erratum in: Elife. 2016;5. pii: e15743. doi: 10.7554/eLife.15743.


Multiset Statistics for Gene Set Analysis.

Newton MA, Wang Z.

Annu Rev Stat Appl. 2015 Apr;2:95-111.


A conserved transcriptional signature of delayed aging and reduced disease vulnerability is partially mediated by SIRT3.

Barger JL, Anderson RM, Newton MA, da Silva C, Vann JA, Pugh TD, Someya S, Prolla TA, Weindruch R.

PLoS One. 2015 Apr 1;10(4):e0120738. doi: 10.1371/journal.pone.0120738. eCollection 2015.


Activation and deactivation of a robust immobilized Cp*Ir-transfer hydrogenation catalyst: a multielement in situ X-ray absorption spectroscopy study.

Sherborne GJ, Chapman MR, Blacker AJ, Bourne RA, Chamberlain TW, Crossley BD, Lucas SJ, McGowan PC, Newton MA, Screen TE, Thompson P, Willans CE, Nguyen BN.

J Am Chem Soc. 2015 Apr 1;137(12):4151-7. doi: 10.1021/ja512868a. Epub 2015 Mar 20.


Tumourigenic canine osteosarcoma cell lines associated with frizzled-6 up-regulation and enhanced side population cell frequency.

de Sá Rodrigues LC, Holmes KE, Thompson V, Newton MA, Stein TJ.

Vet Comp Oncol. 2017 Mar;15(1):78-93. doi: 10.1111/vco.12138. Epub 2015 Feb 16.


Osteosarcoma tissues and cell lines from patients with differing serum alkaline phosphatase concentrations display minimal differences in gene expression patterns.

Rodrigues LC, Holmes KE, Thompson V, Piskun CM, Lana SE, Newton MA, Stein TJ.

Vet Comp Oncol. 2016 Jun;14(2):e58-69. doi: 10.1111/vco.12132. Epub 2015 Feb 3.


Time-resolved, in situ DRIFTS/EDE/MS studies on alumina-supported rhodium catalysts: effects of ceriation and zirconiation on rhodium-CO interactions.

Kroner AB, Newton MA, Tromp M, Roscioni OM, Russell AE, Dent AJ, Prestipino C, Evans J.

Chemphyschem. 2014 Oct 6;15(14):3049-59. doi: 10.1002/cphc.201402122. Epub 2014 Jul 18.


Revealing the dynamic structure of complex solid catalysts using modulated excitation X-ray diffraction.

Ferri D, Newton MA, Di Michiel M, Chiarello GL, Yoon S, Lu Y, Andrieux J.

Angew Chem Int Ed Engl. 2014 Aug 18;53(34):8890-4. doi: 10.1002/anie.201403094. Epub 2014 Jun 5.


How good are simplified models for protein structure prediction?

Shatabda S, Newton MA, Rashid MA, Pham DN, Sattar A.

Adv Bioinformatics. 2014;2014:867179. doi: 10.1155/2014/867179. Epub 2014 Apr 29.


A strategy to identify dominant point mutant modifiers of a quantitative trait.

Dove WF, Shedlovsky A, Clipson L, Amos-Landgraf JM, Halberg RB, Krentz KJ, Boehm FJ, Newton MA, Adams DJ, Keane TM.

G3 (Bethesda). 2014 Apr 17;4(6):1113-21. doi: 10.1534/g3.114.010595.


A Parallel Framework for Multipoint Spiral Search in ab Initio Protein Structure Prediction.

Rashid MA, Shatabda S, Newton MA, Hoque MT, Sattar A.

Adv Bioinformatics. 2014;2014:985968. doi: 10.1155/2014/985968. Epub 2014 Mar 16.


Mixing energy models in genetic algorithms for on-lattice protein structure prediction.

Rashid MA, Newton MA, Hoque MT, Sattar A.

Biomed Res Int. 2013;2013:924137. doi: 10.1155/2013/924137. Epub 2013 Sep 25.


Dynamic tumor growth patterns in a novel murine model of colorectal cancer.

Paul Olson TJ, Hadac JN, Sievers CK, Leystra AA, Deming DA, Zahm CD, Albrecht DM, Nomura A, Nettekoven LA, Plesh LK, Clipson L, Sullivan R, Newton MA, Schelman WR, Halberg RB.

Cancer Prev Res (Phila). 2014 Jan;7(1):105-13. doi: 10.1158/1940-6207.CAPR-13-0163. Epub 2013 Nov 6.


A conditional predictive p-value to compare a multinomial with an overdispersed multinomial in the analysis of T-cell populations.

Pei Q, Zuleger CL, Macklin MD, Albertini MR, Newton MA.

Biostatistics. 2014 Jan;15(1):129-39. doi: 10.1093/biostatistics/kxt039. Epub 2013 Oct 4.


Limited agreement of independent RNAi screens for virus-required host genes owes more to false-negative than false-positive factors.

Hao L, He Q, Wang Z, Craven M, Newton MA, Ahlquist P.

PLoS Comput Biol. 2013;9(9):e1003235. doi: 10.1371/journal.pcbi.1003235. Epub 2013 Sep 19.


Structural characterization of alumina-supported Rh catalysts: effects of ceriation and zirconiation by using metal-organic precursors.

Kroner AB, Newton MA, Tromp M, Russell AE, Dent AJ, Evans J.

Chemphyschem. 2013 Oct 21;14(15):3606-17. doi: 10.1002/cphc.201300537. Epub 2013 Aug 13.

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