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Items: 1 to 50 of 109

1.

N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria.

Newton GL, Rawat M.

mBio. 2019 Jan 15;10(1). pii: e02634-18. doi: 10.1128/mBio.02634-18.

2.

Community Engagement in Academic Health Centers: A Model for Capturing and Advancing Our Successes.

Vitale K, Newton GL, Abraido-Lanza AF, Aguirre AN, Ahmed S, Esmond SL, Evans J, Gelmon SB, Hart C, Hendricks D, McClinton-Brown R, Young SN, Stewart MK, Tumiel-Berhalter LM.

J Community Engagem Scholarsh. 2018;10(1):81-90. Epub 2018 Feb 14.

3.

Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis.

Perera VR, Lapek JD Jr, Newton GL, Gonzalez DJ, Pogliano K.

PLoS One. 2018 Feb 16;13(2):e0192977. doi: 10.1371/journal.pone.0192977. eCollection 2018.

4.

Assembly of a nucleus-like structure during viral replication in bacteria.

Chaikeeratisak V, Nguyen K, Khanna K, Brilot AF, Erb ML, Coker JK, Vavilina A, Newton GL, Buschauer R, Pogliano K, Villa E, Agard DA, Pogliano J.

Science. 2017 Jan 13;355(6321):194-197. doi: 10.1126/science.aal2130.

5.

Application of bacterial cytological profiling to crude natural product extracts reveals the antibacterial arsenal of Bacillus subtilis.

Nonejuie P, Trial RM, Newton GL, Lamsa A, Ranmali Perera V, Aguilar J, Liu WT, Dorrestein PC, Pogliano J, Pogliano K.

J Antibiot (Tokyo). 2016 May;69(5):353-61. doi: 10.1038/ja.2015.116. Epub 2015 Dec 9.

6.

Bacillithiol: a key protective thiol in Staphylococcus aureus.

Perera VR, Newton GL, Pogliano K.

Expert Rev Anti Infect Ther. 2015;13(9):1089-107. doi: 10.1586/14787210.2015.1064309. Epub 2015 Jul 16. Review.

7.

The use of fly larvae for organic waste treatment.

Čičková H, Newton GL, Lacy RC, Kozánek M.

Waste Manag. 2015 Jan;35:68-80. doi: 10.1016/j.wasman.2014.09.026. Epub 2014 Oct 29. Review.

PMID:
25453313
8.

Purification and characterization of the Staphylococcus aureus bacillithiol transferase BstA.

Perera VR, Newton GL, Parnell JM, Komives EA, Pogliano K.

Biochim Biophys Acta. 2014 Sep;1840(9):2851-61. doi: 10.1016/j.bbagen.2014.05.001. Epub 2014 May 10.

9.

Evaluating community engagement in an academic medical center.

Szilagyi PG, Shone LP, Dozier AM, Newton GL, Green T, Bennett NM.

Acad Med. 2014 Apr;89(4):585-95. doi: 10.1097/ACM.0000000000000190.

10.

Functional requirements for bacteriophage growth: gene essentiality and expression in mycobacteriophage Giles.

Dedrick RM, Marinelli LJ, Newton GL, Pogliano K, Pogliano J, Hatfull GF.

Mol Microbiol. 2013 May;88(3):577-89. doi: 10.1111/mmi.12210. Epub 2013 Apr 8.

11.

Characterization of BshA, bacillithiol glycosyltransferase from Staphylococcus aureus and Bacillus subtilis.

Upton H, Newton GL, Gushiken M, Lo K, Holden D, Fahey RC, Rawat M.

FEBS Lett. 2012 Apr 5;586(7):1004-8. doi: 10.1016/j.febslet.2012.02.028. Epub 2012 Mar 6.

12.

Detoxification of toxins by bacillithiol in Staphylococcus aureus.

Newton GL, Fahey RC, Rawat M.

Microbiology. 2012 Apr;158(Pt 4):1117-1126. doi: 10.1099/mic.0.055715-0. Epub 2012 Jan 19. Erratum in: Microbiology. 2012 Sep;158(Pt 9):2450.

13.

Survival dynamics of fecal bacteria in ponds in agricultural watersheds of the Piedmont and Coastal Plain of Georgia.

Jenkins MB, Endale DM, Fisher DS, Adams MP, Lowrance R, Newton GL, Vellidis G.

Water Res. 2012 Jan 1;46(1):176-86. doi: 10.1016/j.watres.2011.10.049. Epub 2011 Nov 2. Erratum in: Water Res. 2013 Mar 15;47(4):1708-9.

PMID:
22088271
14.

The DinB superfamily includes novel mycothiol, bacillithiol, and glutathione S-transferases.

Newton GL, Leung SS, Wakabayashi JI, Rawat M, Fahey RC.

Biochemistry. 2011 Dec 13;50(49):10751-60. doi: 10.1021/bi201460j. Epub 2011 Nov 17.

15.

Reducing concentrated animal feeding operations permitting requirements.

Centner TJ, Newton GL.

J Anim Sci. 2011 Dec;89(12):4364-9. doi: 10.2527/jas.2011-4256. Epub 2011 Aug 5.

PMID:
21821805
16.

The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth.

Hatzios SK, Schelle MW, Newton GL, Sogi KM, Holsclaw CM, Fahey RC, Bertozzi CR.

Bioorg Med Chem Lett. 2011 Sep 1;21(17):4956-9. doi: 10.1016/j.bmcl.2011.06.057. Epub 2011 Jun 29.

17.

Chemical and Chemoenzymatic syntheses of bacillithiol: a unique low-molecular-weight thiol amongst low G + C Gram-positive bacteria.

Sharma SV, Jothivasan VK, Newton GL, Upton H, Wakabayashi JI, Kane MG, Roberts AA, Rawat M, La Clair JJ, Hamilton CJ.

Angew Chem Int Ed Engl. 2011 Jul 25;50(31):7101-4. doi: 10.1002/anie.201100196. Epub 2011 Jul 12. No abstract available.

PMID:
21751306
18.

Evaluation of NTF1836 as an inhibitor of the mycothiol biosynthetic enzyme MshC in growing and non-replicating Mycobacterium tuberculosis.

Newton GL, Buchmeier N, La Clair JJ, Fahey RC.

Bioorg Med Chem. 2011 Jul 1;19(13):3956-64. doi: 10.1016/j.bmc.2011.05.028. Epub 2011 May 24.

19.

Organic hydroperoxide resistance protein and ergothioneine compensate for loss of mycothiol in Mycobacterium smegmatis mutants.

Ta P, Buchmeier N, Newton GL, Rawat M, Fahey RC.

J Bacteriol. 2011 Apr;193(8):1981-90. doi: 10.1128/JB.01402-10. Epub 2011 Feb 18.

20.

Characterization of the N-acetyl-α-D-glucosaminyl l-malate synthase and deacetylase functions for bacillithiol biosynthesis in Bacillus anthracis .

Parsonage D, Newton GL, Holder RC, Wallace BD, Paige C, Hamilton CJ, Dos Santos PC, Redinbo MR, Reid SD, Claiborne A.

Biochemistry. 2010 Sep 28;49(38):8398-414. doi: 10.1021/bi100698n.

21.

Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.

Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6. doi: 10.1073/pnas.1000928107. Epub 2010 Mar 22.

22.

Bacillithiol is an antioxidant thiol produced in Bacilli.

Newton GL, Rawat M, La Clair JJ, Jothivasan VK, Budiarto T, Hamilton CJ, Claiborne A, Helmann JD, Fahey RC.

Nat Chem Biol. 2009 Sep;5(9):625-7. doi: 10.1038/nchembio.189. Epub 2009 Jul 5.

23.

Characterization of a mycothiol ligase mutant of Rhodococcus jostii RHA1.

Dosanjh M, Newton GL, Davies J.

Res Microbiol. 2008 Nov-Dec;159(9-10):643-50. doi: 10.1016/j.resmic.2008.08.006. Epub 2008 Sep 12.

PMID:
18832026
24.

Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria.

Newton GL, Buchmeier N, Fahey RC.

Microbiol Mol Biol Rev. 2008 Sep;72(3):471-94. doi: 10.1128/MMBR.00008-08. Review.

25.

Unusual production of glutathione in Actinobacteria.

Johnson T, Newton GL, Fahey RC, Rawat M.

Arch Microbiol. 2009 Jan;191(1):89-93. doi: 10.1007/s00203-008-0423-1. Epub 2008 Aug 22.

26.

An N-acyl homolog of mycothiol is produced in marine actinomycetes.

Newton GL, Jensen PR, Macmillan JB, Fenical W, Fahey RC.

Arch Microbiol. 2008 Nov;190(5):547-57. doi: 10.1007/s00203-008-0405-3. Epub 2008 Jul 16.

27.

Meeting environmental requirements for the land application of manure.

Centner TJ, Newton GL.

J Anim Sci. 2008 Nov;86(11):3228-34. doi: 10.2527/jas.2008-1161. Epub 2008 Jun 6.

PMID:
18539820
28.

Regulation of mycothiol metabolism by sigma(R) and the thiol redox sensor anti-sigma factor RsrA.

Newton GL, Fahey RC.

Mol Microbiol. 2008 May;68(4):805-9. doi: 10.1111/j.1365-2958.2008.06222.x.

29.

Mycothiol import by Mycobacterium smegmatis and function as a resource for metabolic precursors and energy production.

Bzymek KP, Newton GL, Ta P, Fahey RC.

J Bacteriol. 2007 Oct;189(19):6796-805. Epub 2007 Jul 20.

30.

Structure of the type III pantothenate kinase from Bacillus anthracis at 2.0 A resolution: implications for coenzyme A-dependent redox biology.

Nicely NI, Parsonage D, Paige C, Newton GL, Fahey RC, Leonardi R, Jackowski S, Mallett TC, Claiborne A.

Biochemistry. 2007 Mar 20;46(11):3234-45. Epub 2007 Feb 27.

31.

Biochemistry of the initial steps of mycothiol biosynthesis.

Newton GL, Ta P, Bzymek KP, Fahey RC.

J Biol Chem. 2006 Nov 10;281(45):33910-20. Epub 2006 Aug 28.

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37.

Nonprotein thiols and disulfides in rat epididymal spermatozoa and epididymal fluid: role of gamma-glutamyl-transpeptidase in sperm maturation.

Seligman J, Newton GL, Fahey RC, Shalgi R, Kosower NS.

J Androl. 2005 Sep-Oct;26(5):629-37; discussion 638-40.

38.

Radioprotection of plasmid DNA by oligolysines.

Newton GL, Ly A, Tran NQ, Ward JF, Milligan JR.

Int J Radiat Biol. 2004 Sep;80(9):643-51.

PMID:
15586884
39.

Water quality and the grazing animal.

Hubbard RK, Newton GL, Hill GM.

J Anim Sci. 2004;82 E-Suppl:E255-263. Review.

PMID:
15471806
40.

Mycothiol is essential for growth of Mycobacterium tuberculosis Erdman.

Sareen D, Newton GL, Fahey RC, Buchmeier NA.

J Bacteriol. 2003 Nov;185(22):6736-40.

41.

Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase.

Steffek M, Newton GL, Av-Gay Y, Fahey RC.

Biochemistry. 2003 Oct 21;42(41):12067-76.

PMID:
14556638
42.

Managing manure nutrients through multi-crop forage production.

Newton GL, Bernard JK, Hubbard RK, Allison JR, Lowrance RR, Gascho GJ, Gates RN, Vellidis G.

J Dairy Sci. 2003 Jun;86(6):2243-52.

43.

The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA).

Newton GL, Koledin T, Gorovitz B, Rawat M, Fahey RC, Av-Gay Y.

J Bacteriol. 2003 Jun;185(11):3476-9.

44.

Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics.

Buchmeier NA, Newton GL, Koledin T, Fahey RC.

Mol Microbiol. 2003 Mar;47(6):1723-32.

45.

Inhibition and kinetics of mycobacterium tuberculosis and mycobacterium smegmatis mycothiol-S-conjugate amidase by natural product inhibitors.

Nicholas GM, Eckman LL, Newton GL, Fahey RC, Ray S, Bewley CA.

Bioorg Med Chem. 2003 Feb 20;11(4):601-8.

PMID:
12538025
46.

Mycothiol biochemistry.

Newton GL, Fahey RC.

Arch Microbiol. 2002 Dec;178(6):388-94. Epub 2002 Sep 3. Review.

PMID:
12420157
47.

Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics.

Rawat M, Newton GL, Ko M, Martinez GJ, Fahey RC, Av-Gay Y.

Antimicrob Agents Chemother. 2002 Nov;46(11):3348-55.

48.

Identification of the mycothiol synthase gene (mshD) encoding the acetyltransferase producing mycothiol in actinomycetes.

Koledin T, Newton GL, Fahey RC.

Arch Microbiol. 2002 Nov;178(5):331-7. Epub 2002 Aug 15.

PMID:
12375100
50.

Blood thiols following amifostine and mesna infusions, a pediatric oncology group study.

Souid AK, Fahey RC, Aktas MK, Sayin OA, Karjoo S, Newton GL, Sadowitz PD, Dubowy RL, Bernstein ML.

Drug Metab Dispos. 2001 Nov;29(11):1460-6.

PMID:
11602522

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