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Items: 1 to 50 of 341

1.

Activation of Discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell division.

Golub O, Wee B, Newman RA, Paterson NM, Prehoda KE.

Elife. 2017 Nov 29;6. pii: e32137. doi: 10.7554/eLife.32137.

2.

Sharp-Tailed Grouse Nest Survival and Nest Predator Habitat Use in North Dakota's Bakken Oil Field.

Burr PC, Robinson AC, Larsen RT, Newman RA, Ellis-Felege SN.

PLoS One. 2017 Jan 12;12(1):e0170177. doi: 10.1371/journal.pone.0170177. eCollection 2017.

3.

Water-soluble egg membrane enhances the immunoactivating properties of an Aloe vera-based extract of Nerium oleander leaves.

Benson KF, Newman RA, Jensen GS.

Clin Cosmet Investig Dermatol. 2016 Nov 3;9:393-403. eCollection 2016.

4.

Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer.

Al Shemaili J, Parekh KA, Newman RA, Hellman B, Woodward C, Adem A, Collin P, Adrian TE.

Mar Drugs. 2016 Jun 17;14(6). pii: E115. doi: 10.3390/md14060115.

5.

Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke.

Van Kanegan MJ, Dunn DE, Kaltenbach LS, Shah B, He DN, McCoy DD, Yang P, Peng J, Shen L, Du L, Cichewicz RH, Newman RA, Lo DC.

Sci Rep. 2016 May 12;6:25626. doi: 10.1038/srep25626.

6.

Experiences of Children With Gay Fathers.

Perrin EC, Pinderhughes EE, Mattern K, Hurley SM, Newman RA.

Clin Pediatr (Phila). 2016 Dec;55(14):1305-1317. doi: 10.1177/0009922816632346. Epub 2016 Jul 20.

PMID:
26965032
7.

Antioxidant, anti-inflammatory, anti-apoptotic, and skin regenerative properties of an Aloe vera-based extract of Nerium oleander leaves (nae-8(®)).

Benson KF, Newman RA, Jensen GS.

Clin Cosmet Investig Dermatol. 2015 May 6;8:239-48. doi: 10.2147/CCID.S79871. eCollection 2015.

8.

Response to: Does the Nerium oleander extract PBI-05204 have potential for pancreatic cancer?

Newman RA, Yang P.

Invest New Drugs. 2015 Jun;33(3):788-9. doi: 10.1007/s10637-015-0208-8. Epub 2015 Jan 20. No abstract available.

PMID:
25597755
9.

PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway.

Pan Y, Rhea P, Tan L, Cartwright C, Lee HJ, Ravoori MK, Addington C, Gagea M, Kundra V, Kim SJ, Newman RA, Yang P.

Invest New Drugs. 2015 Apr;33(2):271-9. doi: 10.1007/s10637-014-0190-6. Epub 2014 Dec 6.

10.

Calcium-dependent energetics of calmodulin domain interactions with regulatory regions of the Ryanodine Receptor Type 1 (RyR1).

Newman RA, Sorensen BR, Kilpatrick AM, Shea MA.

Biophys Chem. 2014 Sep-Oct;193-194:35-49. doi: 10.1016/j.bpc.2014.07.004. Epub 2014 Jul 30.

11.

First-in-human study of pbi-05204, an oleander-derived inhibitor of akt, fgf-2, nf-κΒ and p70s6k, in patients with advanced solid tumors.

Hong DS, Henary H, Falchook GS, Naing A, Fu S, Moulder S, Wheler JJ, Tsimberidou A, Durand JB, Khan R, Yang P, Johansen M, Newman RA, Kurzrock R.

Invest New Drugs. 2014 Dec;32(6):1204-12. doi: 10.1007/s10637-014-0127-0. Epub 2014 Jun 13.

PMID:
24919855
12.

BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin.

Van Kanegan MJ, He DN, Dunn DE, Yang P, Newman RA, West AE, Lo DC.

J Neurosci. 2014 Jan 15;34(3):963-8. doi: 10.1523/JNEUROSCI.2700-13.2014.

13.

Caffeine gum minimizes sleep inertia.

Newman RA, Kamimori GH, Wesensten NJ, Picchioni D, Balkin TJ.

Percept Mot Skills. 2013 Feb;116(1):280-93.

PMID:
23829154
14.

Simultaneous reduction of particulate matter and NO(x) emissions using 4-way catalyzed filtration systems.

Swanson JJ, Watts WF, Newman RA, Ziebarth RR, Kittelson DB.

Environ Sci Technol. 2013 May 7;47(9):4521-7. doi: 10.1021/es304971h. Epub 2013 Apr 15.

PMID:
23550802
16.

Anticancer activity of fish oils against human lung cancer is associated with changes in formation of PGE2 and PGE3 and alteration of Akt phosphorylation.

Yang P, Cartwright C, Chan D, Ding J, Felix E, Pan Y, Pang J, Rhea P, Block K, Fischer SM, Newman RA.

Mol Carcinog. 2014 Jul;53(7):566-77. doi: 10.1002/mc.22008. Epub 2013 Jan 31.

17.

Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity.

Singh S, Shenoy S, Nehete PN, Yang P, Nehete B, Fontenot D, Yang G, Newman RA, Sastry KJ.

Fitoterapia. 2013 Jan;84:32-9. doi: 10.1016/j.fitote.2012.10.017. Epub 2012 Nov 2.

PMID:
23127567
18.

Cellular location and expression of Na+, K+ -ATPase α subunits affect the anti-proliferative activity of oleandrin.

Yang P, Cartwright C, Efuet E, Hamilton SR, Wistuba II, Menter D, Addington C, Shureiqi I, Newman RA.

Mol Carcinog. 2014 Apr;53(4):253-63. doi: 10.1002/mc.21968. Epub 2012 Oct 16.

19.

Arachidonic acid metabolism in human prostate cancer.

Yang P, Cartwright CA, Li J, Wen S, Prokhorova IN, Shureiqi I, Troncoso P, Navone NM, Newman RA, Kim J.

Int J Oncol. 2012 Oct;41(4):1495-503. doi: 10.3892/ijo.2012.1588. Epub 2012 Aug 10.

20.

Perioperative polyphenon E, a green tea extract, does not affect the wound complication rate in mice after sham laparotomy yet has an inhibitory effect on wound healing.

Hoffman A, Baxter R, Nasar A, Gardner TR, Kumara S, Cordon-Cardo C, Ahmed A, Newman RA, Zmora O, Whelan RL.

Surg Innov. 2012 Dec;19(4):399-406. doi: 10.1177/1553350612436565. Epub 2012 Mar 18.

PMID:
22431911
21.

Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites.

Menter DG, Ramsauer VP, Harirforoosh S, Chakraborty K, Yang P, Hsi L, Newman RA, Krishnan K.

PLoS One. 2011;6(12):e28813. doi: 10.1371/journal.pone.0028813. Epub 2011 Dec 22.

22.

In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models.

Dunn DE, He DN, Yang P, Johansen M, Newman RA, Lo DC.

J Neurochem. 2011 Nov;119(4):805-14. doi: 10.1111/j.1471-4159.2011.07439.x. Epub 2011 Sep 26.

23.

Zyflamend mediates therapeutic induction of autophagy to apoptosis in melanoma cells.

Ekmekcioglu S, Chattopadhyay C, Akar U, Gabisi A Jr, Newman RA, Grimm EA.

Nutr Cancer. 2011;63(6):940-9. doi: 10.1080/01635581.2011.586488. Epub 2011 Jul 11.

PMID:
21745040
24.

Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach.

Scott MC, Sarver AL, Gavin KJ, Thayanithy V, Getzy DM, Newman RA, Cutter GR, Lindblad-Toh K, Kisseberth WC, Hunter LE, Subramanian S, Breen M, Modiano JF.

Bone. 2011 Sep;49(3):356-67. doi: 10.1016/j.bone.2011.05.008. Epub 2011 May 15.

25.

γ-Tocotrienol induces growth arrest through a novel pathway with TGFβ2 in prostate cancer.

Campbell SE, Rudder B, Phillips RB, Whaley SG, Stimmel JB, Leesnitzer LM, Lightner J, Dessus-Babus S, Duffourc M, Stone WL, Menter DG, Newman RA, Yang P, Aggarwal BB, Krishnan K.

Free Radic Biol Med. 2011 May 15;50(10):1344-54. doi: 10.1016/j.freeradbiomed.2011.02.007. Epub 2011 Feb 16.

PMID:
21335085
26.
27.

Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis.

Shureiqi I, Chen D, Day RS, Zuo X, Hochman FL, Ross WA, Cole RA, Moy O, Morris JS, Xiao L, Newman RA, Yang P, Lippman SM.

Cancer Prev Res (Phila). 2010 Jul;3(7):829-38. doi: 10.1158/1940-6207.CAPR-09-0110. Epub 2010 Jun 22.

28.

Transgenic expression of 15-lipoxygenase 2 (15-LOX2) in mouse prostate leads to hyperplasia and cell senescence.

Suraneni MV, Schneider-Broussard R, Moore JR, Davis TC, Maldonado CJ, Li H, Newman RA, Kusewitt D, Hu J, Yang P, Tang DG.

Oncogene. 2010 Jul 29;29(30):4261-75. doi: 10.1038/onc.2010.197. Epub 2010 May 31.

29.

Pomegranate (Punica granatum) seed linolenic acid isomers: concentration-dependent modulation of estrogen receptor activity.

Tran HN, Bae SY, Song BH, Lee BH, Bae YS, Kim YH, Lansky EP, Newman RA.

Endocr Res. 2010 Jan;35(1):1-16. doi: 10.3109/07435800903524161.

PMID:
20136514
30.

Biological activity of celecoxib in the bronchial epithelium of current and former smokers.

Kim ES, Hong WK, Lee JJ, Mao L, Morice RC, Liu DD, Jimenez CA, Eapen GA, Lotan R, Tang X, Newman RA, Wistuba II, Kurie JM.

Cancer Prev Res (Phila). 2010 Feb;3(2):148-59. doi: 10.1158/1940-6207.CAPR-09-0233. Epub 2010 Jan 26.

31.

Response to 'Probable hepatotoxicity related to Nerium oleander extract in a patient with metastatic synovial sarcoma of the knee'.

Block KI, Gyllenhaal C, Newman RA.

J Altern Complement Med. 2009 Dec;15(12):1269; author reply 1271. doi: 10.1089/acm.2009.0211. No abstract available.

PMID:
19958106
32.

Phase I trial of a combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in advanced malignancies.

Hong DS, Sebti SM, Newman RA, Blaskovich MA, Ye L, Gagel RF, Moulder S, Wheler JJ, Naing A, Tannir NM, Ng CS, Sherman SI, El Naggar AK, Khan R, Trent J, Wright JJ, Kurzrock R.

Clin Cancer Res. 2009 Nov 15;15(22):7061-8. doi: 10.1158/1078-0432.CCR-09-1241. Epub 2009 Nov 10.

33.

Gamma tocopherol upregulates the expression of 15-S-HETE and induces growth arrest through a PPAR gamma-dependent mechanism in PC-3 human prostate cancer cells.

Campbell SE, Musich PR, Whaley SG, Stimmel JB, Leesnitzer LM, Dessus-Babus S, Duffourc M, Stone W, Newman RA, Yang P, Krishnan K.

Nutr Cancer. 2009;61(5):649-62. doi: 10.1080/01635580902825654.

PMID:
19838939
34.

Pomegranate fruit extract impairs invasion and motility in human breast cancer.

Khan GN, Gorin MA, Rosenthal D, Pan Q, Bao LW, Wu ZF, Newman RA, Pawlus AD, Yang P, Lansky EP, Merajver SD.

Integr Cancer Ther. 2009 Sep;8(3):242-53. doi: 10.1177/1534735409341405.

PMID:
19815594
35.

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice.

Moghaddam SJ, Barta P, Mirabolfathinejad SG, Ammar-Aouchiche Z, Garza NT, Vo TT, Newman RA, Aggarwal BB, Evans CM, Tuvim MJ, Lotan R, Dickey BF.

Carcinogenesis. 2009 Nov;30(11):1949-56. doi: 10.1093/carcin/bgp229. Epub 2009 Sep 30.

36.

Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer.

Meng Z, Yang P, Shen Y, Bei W, Zhang Y, Ge Y, Newman RA, Cohen L, Liu L, Thornton B, Chang DZ, Liao Z, Kurzrock R.

Cancer. 2009 Nov 15;115(22):5309-18. doi: 10.1002/cncr.24602.

37.

Oleandrin-mediated inhibition of human tumor cell proliferation: importance of Na,K-ATPase alpha subunits as drug targets.

Yang P, Menter DG, Cartwright C, Chan D, Dixon S, Suraokar M, Mendoza G, Llansa N, Newman RA.

Mol Cancer Ther. 2009 Aug;8(8):2319-28. doi: 10.1158/1535-7163.MCT-08-1085. Epub 2009 Aug 11.

38.

Pharmacokinetics of caffeic acid phenethyl ester and its catechol-ring fluorinated derivative following intravenous administration to rats.

Wang X, Pang J, Maffucci JA, Pade DS, Newman RA, Kerwin SM, Bowman PD, Stavchansky S.

Biopharm Drug Dispos. 2009 Jul;30(5):221-8. doi: 10.1002/bdd.657.

PMID:
19544289
39.

15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.

Yan M, Myung SJ, Fink SP, Lawrence E, Lutterbaugh J, Yang P, Zhou X, Liu D, Rerko RM, Willis J, Dawson D, Tai HH, Barnholtz-Sloan JS, Newman RA, Bertagnolli MM, Markowitz SD.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9409-13. doi: 10.1073/pnas.0902367106. Epub 2009 May 22.

40.

Survival impact of integrative cancer care in advanced metastatic breast cancer.

Block KI, Gyllenhaal C, Tripathy D, Freels S, Mead MN, Block PB, Steinmann WC, Newman RA, Shoham J.

Breast J. 2009 Jul-Aug;15(4):357-66. doi: 10.1111/j.1524-4741.2009.00739.x. Epub 2009 May 12.

PMID:
19470134
41.

Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway.

Duffield-Lillico AJ, Boyle JO, Zhou XK, Ghosh A, Butala GS, Subbaramaiah K, Newman RA, Morrow JD, Milne GL, Dannenberg AJ.

Cancer Prev Res (Phila). 2009 Apr;2(4):322-9. doi: 10.1158/1940-6207.CAPR-09-0005. Epub 2009 Mar 31.

42.

Intramolecular interactions between the SRC homology 3 and guanylate kinase domains of discs large regulate its function in asymmetric cell division.

Newman RA, Prehoda KE.

J Biol Chem. 2009 May 8;284(19):12924-32. doi: 10.1074/jbc.M809304200. Epub 2009 Mar 4.

43.

Re: Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?

Block K, Koch A, Mead M, Newman RA, Gyllenhaal C.

J Natl Cancer Inst. 2009 Jan 21;101(2):124-5; author reply 125-6. doi: 10.1093/jnci/djn446. Epub 2009 Jan 13. No abstract available.

PMID:
19141775
44.

NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer.

Hughes D, Otani T, Yang P, Newman RA, Yantiss RK, Altorki NK, Port JL, Yan M, Markowitz SD, Mazumdar M, Tai HH, Subbaramaiah K, Dannenberg AJ.

Cancer Prev Res (Phila). 2008 Sep;1(4):241-9. doi: 10.1158/1940-6207.CAPR-08-0055.

45.

Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid.

Brown PH, Subbaramaiah K, Salmon AP, Baker R, Newman RA, Yang P, Zhou XK, Bissonnette RP, Dannenberg AJ, Howe LR.

Cancer Prev Res (Phila). 2008 Aug;1(3):208-14. doi: 10.1158/1940-6207.CAPR-08-0021.

46.

Regulation of prostaglandin transporters in colorectal neoplasia.

Holla VR, Backlund MG, Yang P, Newman RA, DuBois RN.

Cancer Prev Res (Phila). 2008 Jul;1(2):93-9. doi: 10.1158/1940-6207.CAPR-07-0009. Epub 2008 Mar 19.

47.

Thermodynamics and conformational change governing domain-domain interactions of calmodulin.

O'Donnell SE, Newman RA, Witt TJ, Hultman R, Froehlig JR, Christensen AP, Shea MA.

Methods Enzymol. 2009;466:503-26. doi: 10.1016/S0076-6879(09)66021-3. Epub 2009 Nov 13.

PMID:
21609874
48.

Determinants of human and mouse melanoma cell sensitivities to oleandrin.

Lin Y, Dubinsky WP, Ho DH, Felix E, Newman RA.

J Exp Ther Oncol. 2008;7(3):195-205.

PMID:
19066128
49.

Development and characterization of nine polymorphic microsatellite markers for Mexican spadefoot toads (Spea multiplicata) with cross-amplification in Plains spadefoot toads (S. bombifrons).

Rice AM, Pearse DE, Becker T, Newman RA, Lebonville C, Harper GR, Pfennig KS.

Mol Ecol Resour. 2008 Nov;8(6):1386-9. doi: 10.1111/j.1755-0998.2008.02291.x.

PMID:
21586053
50.

Review of the apoptosis pathways in pancreatic cancer and the anti-apoptotic effects of the novel sea cucumber compound, Frondoside A.

Li X, Roginsky AB, Ding XZ, Woodward C, Collin P, Newman RA, Bell RH Jr, Adrian TE.

Ann N Y Acad Sci. 2008 Sep;1138:181-98. doi: 10.1196/annals.1414.025.

PMID:
18837899

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