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Items: 1 to 50 of 299

1.

UVEAL METASTASIS BASED ON PATIENT AGE IN 1,111 PATIENTS: Comparison of Clinical Features and Outcomes Per Age Category.

Shields CL, Acaba-Berrocal LA, Selzer EB, Mayro EL, Newman JH, Malik K, Welch RJ, Shields JA.

Retina. 2020 Feb;40(2):204-213. doi: 10.1097/IAE.0000000000002364.

PMID:
31972789
2.

Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer.

Newman JH, Chesson CB, Herzog NL, Bommareddy PK, Aspromonte SM, Pepe R, Estupinian R, Aboelatta MM, Buddhadev S, Tarabichi S, Lee M, Li S, Medina DJ, Giurini EF, Gupta KH, Guevara-Aleman G, Rossi M, Nowicki C, Abed A, Goldufsky JW, Broucek JR, Redondo RE, Rotter D, Jhawar SR, Wang SJ, Kohlhapp FJ, Kaufman HL, Thomas PG, Gupta V, Kuzel TM, Reiser J, Paras J, Kane MP, Singer EA, Malhotra J, Denzin LK, Sant'Angelo DB, Rabson AB, Lee LY, Lasfar A, Langenfeld J, Schenkel JM, Fidler MJ, Ruiz ES, Marzo AL, Rudra JS, Silk AW, Zloza A.

Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1119-1128. doi: 10.1073/pnas.1904022116. Epub 2019 Dec 30.

3.

BMPR2 dysfunction impairs insulin signaling and glucose homeostasis in cardiomyocytes.

Hemnes AR, Fessel JP, Chen X, Zhu S, Fortune NL, Jetter C, Freeman M, Newman JH, West JD, Talati MH.

Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1;318(2):L429-L441. doi: 10.1152/ajplung.00555.2018. Epub 2019 Dec 18.

PMID:
31850803
4.

Uveal metastasis in 1111 patients: Interval to metastasis and overall survival based on timing of primary cancer diagnosis.

Welch RJ, Malik K, Mayro EL, Newman JH, Honig SE, Ang SM, Selzer EB, Acaba-Berrocal LA, McGarrey MP, Graf AE, Considine SP, Shields JA, Shields CL.

Saudi J Ophthalmol. 2019 Jul-Sep;33(3):229-237. doi: 10.1016/j.sjopt.2019.07.006. Epub 2019 Jul 25.

5.

Echocardiographic Detection of Occult Diastolic Dysfunction in Pulmonary Hypertension After Fluid Challenge.

Agrawal V, D'Alto M, Naeije R, Romeo E, Xu M, Assad TR, Robbins IM, Newman JH, Pugh ME, Hemnes AR, Brittain EL.

J Am Heart Assoc. 2019 Sep 3;8(17):e012504. doi: 10.1161/JAHA.119.012504. Epub 2019 Aug 31.

6.

Uveal Metastasis Based on Patient Sex in 2214 Tumors of 1111 Patients. A Comparison of Female Versus Male Clinical Features and Outcomes.

Welch RJ, Malik K, Considine SP, Acaba-Berrocal LA, Selzer EB, Newman JH, Shields JA, Shields CL.

Asia Pac J Ophthalmol (Phila). 2019 Jul-Aug;8(4):298-303. doi: 10.1097/APO.0000000000000247.

7.

Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration.

Stein MN, Malhotra J, Tarapore RS, Malhotra U, Silk AW, Chan N, Rodriguez L, Aisner J, Aiken RD, Mayer T, Haffty BG, Newman JH, Aspromonte SM, Bommareddy PK, Estupinian R, Chesson CB, Sadimin ET, Li S, Medina DJ, Saunders T, Frankel M, Kareddula A, Damare S, Wesolowsky E, Gabel C, El-Deiry WS, Prabhu VV, Allen JE, Stogniew M, Oster W, Bertino JR, Libutti SK, Mehnert JM, Zloza A.

J Immunother Cancer. 2019 May 22;7(1):136. doi: 10.1186/s40425-019-0599-8.

8.

Choroidal amelanotic tumours: clinical differentiation of benign from malignant lesions in 5586 cases.

Welch RJ, Newman JH, Honig SE, Mayro EL, McGarrey M, Graf AE, Selzer EB, Acaba-Berrocal LA, Considine SP, Malik K, Shields JA, Shields CL.

Br J Ophthalmol. 2020 Feb;104(2):194-201. doi: 10.1136/bjophthalmol-2018-313680. Epub 2019 Apr 25.

PMID:
31023712
9.

Whole genome sequencing reveals novel IGHMBP2 variant leading to unique cryptic splice-site and Charcot-Marie-Tooth phenotype with early onset symptoms.

Cassini TA, Duncan L, Rives LC, Newman JH, Phillips JA, Koziura ME, Brault J, Hamid R, Cogan J; Undiagnosed Diseases Network.

Mol Genet Genomic Med. 2019 Jun;7(6):e00676. doi: 10.1002/mgg3.676. Epub 2019 Apr 25.

10.

IgG4-related disease: Association with a rare gene variant expressed in cytotoxic T cells.

Newman JH, Shaver A, Sheehan JH, Mallal S, Stone JH, Pillai S, Bastarache L, Riebau D, Allard-Chamard H, Stone WM, Perugino C, Pilkinton M, Smith SA, McDonnell WJ, Capra JA, Meiler J, Cogan J, Xing K, Mahajan VS, Mattoo H, Hamid R, Phillips JA 3rd; Undiagnosed Disease Network.

Mol Genet Genomic Med. 2019 Jun;7(6):e686. doi: 10.1002/mgg3.686. Epub 2019 Apr 16.

11.

Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia.

Sellnow RC, Newman JH, Chambers N, West AR, Steece-Collier K, Sandoval IM, Benskey MJ, Bishop C, Manfredsson FP.

Acta Neuropathol Commun. 2019 Jan 15;7(1):8. doi: 10.1186/s40478-018-0653-7.

12.

Human PAH is characterized by a pattern of lipid-related insulin resistance.

Hemnes AR, Luther JM, Rhodes CJ, Burgess JP, Carlson J, Fan R, Fessel JP, Fortune N, Gerszten RE, Halliday SJ, Hekmat R, Howard L, Newman JH, Niswender KD, Pugh ME, Robbins IM, Sheng Q, Shibao CA, Shyr Y, Sumner S, Talati M, Wharton J, Wilkins MR, Ye F, Yu C, West J, Brittain EL.

JCI Insight. 2019 Jan 10;4(1). pii: 123611. doi: 10.1172/jci.insight.123611. [Epub ahead of print]

13.

UVEAL METASTASIS BASED ON PATIENT AGE IN 1,111 PATIENTS: Comparison of Clinical Features and Outcomes Per Age Category.

Shields CL, Acaba-Berrocal LA, Selzer EB, Mayro EL, Newman JH, Malik K, Welch RJ, Shields JA.

Retina. 2018 Oct 16. doi: 10.1097/IAE.0000000000002364. [Epub ahead of print]

PMID:
30334925
14.

Uveal Metastasis: Clinical Features and Survival Outcome of 2214 Tumors in 1111 Patients Based on Primary Tumor Origin.

Shields CL, Welch RJ, Malik K, Acaba-Berrocal LA, Selzer EB, Newman JH, Mayro EL, Constantinescu AB, Spencer MA, McGarrey MP, Knapp AN, Graf AE, Altman AJ, Considine SP, Shields JA.

Middle East Afr J Ophthalmol. 2018 Apr-Jun;25(2):81-90. doi: 10.4103/meajo.MEAJO_6_18.

15.

The Light at the End of the Long Pulmonary Hypertension Tunnel Brightens.

Voelkel NF, Newman JH.

Am J Respir Crit Care Med. 2018 Sep 15;198(6):818-820. doi: 10.1164/rccm.201802-0325LE. No abstract available.

PMID:
29944843
16.

A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension.

Hemnes AR, Rathinasabapathy A, Austin EA, Brittain EL, Carrier EJ, Chen X, Fessel JP, Fike CD, Fong P, Fortune N, Gerszten RE, Johnson JA, Kaplowitz M, Newman JH, Piana R, Pugh ME, Rice TW, Robbins IM, Wheeler L, Yu C, Loyd JE, West J.

Eur Respir J. 2018 Jun 21;51(6). pii: 1702638. doi: 10.1183/13993003.02638-2017. Print 2018 Jun.

17.

Rare Variants in the Gene ALPL That Cause Hypophosphatasia Are Strongly Associated With Ovarian and Uterine Disorders.

Dahir KM, Tilden DR, Warner JL, Bastarache L, Smith DK, Gifford A, Ramirez AH, Simmons JS, Black MM, Newman JH, Denny JC.

J Clin Endocrinol Metab. 2018 Jun 1;103(6):2234-2243. doi: 10.1210/jc.2017-02676.

18.

Novel bone morphogenetic protein receptor inhibitor JL5 suppresses tumor cell survival signaling and induces regression of human lung cancer.

Newman JH, Augeri DJ, NeMoyer R, Malhotra J, Langenfeld E, Chesson CB, Dobias NS, Lee MJ, Tarabichi S, Jhawar SR, Bommareddy PK, Marshall S, Sadimin ET, Kerrigan JE, Goedken M, Minerowicz C, Jabbour SK, Li S, Carayannopolous MO, Zloza A, Langenfeld J.

Oncogene. 2018 Jul;37(27):3672-3685. doi: 10.1038/s41388-018-0156-9. Epub 2018 Apr 6.

PMID:
29622797
19.

Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment.

Wagner J, Kline CL, Zhou L, Campbell KS, MacFarlane AW, Olszanski AJ, Cai KQ, Hensley HH, Ross EA, Ralff MD, Zloza A, Chesson CB, Newman JH, Kaufman H, Bertino J, Stein M, El-Deiry WS.

J Clin Invest. 2018 Jun 1;128(6):2325-2338. doi: 10.1172/JCI96711. Epub 2018 Apr 30.

20.

Phenotypic heterogeneity of ZMPSTE24 deficiency.

Cassini TA, Robertson AK, Bican AG, Cogan JD, Hannig VL, Newman JH, Hamid R, Phillips JA 3rd; Undiagnosed Diseases Network.

Am J Med Genet A. 2018 May;176(5):1175-1179. doi: 10.1002/ajmg.a.38493. Epub 2018 Jan 17.

21.

Infection: a Cause of and Cure for Cancer.

Newman JH, Zloza A.

Curr Pharmacol Rep. 2017;3(6):315-320. doi: 10.1007/s40495-017-0109-y. Epub 2017 Oct 5. Review.

22.

PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics.

Hemnes AR, Beck GJ, Newman JH, Abidov A, Aldred MA, Barnard J, Berman Rosenzweig E, Borlaug BA, Chung WK, Comhair SAA, Erzurum SC, Frantz RP, Gray MP, Grunig G, Hassoun PM, Hill NS, Horn EM, Hu B, Lempel JK, Maron BA, Mathai SC, Olman MA, Rischard FP, Systrom DM, Tang WHW, Waxman AB, Xiao L, Yuan JX, Leopold JA; PVDOMICS Study Group.

Circ Res. 2017 Oct 27;121(10):1136-1139. doi: 10.1161/CIRCRESAHA.117.311737. No abstract available.

23.

Pulmonary vascular effect of insulin in a rodent model of pulmonary arterial hypertension.

Trammell AW, Talati M, Blackwell TR, Fortune NL, Niswender KD, Fessel JP, Newman JH, West JD, Hemnes AR.

Pulm Circ. 2017 Jul-Sep;7(3):624-634. doi: 10.1086/689908. Epub 2017 Aug 7.

24.

Enhancing Insights into Pulmonary Vascular Disease through a Precision Medicine Approach. A Joint NHLBI-Cardiovascular Medical Research and Education Fund Workshop Report.

Newman JH, Rich S, Abman SH, Alexander JH, Barnard J, Beck GJ, Benza RL, Bull TM, Chan SY, Chun HJ, Doogan D, Dupuis J, Erzurum SC, Frantz RP, Geraci M, Gillies H, Gladwin M, Gray MP, Hemnes AR, Herbst RS, Hernandez AF, Hill NS, Horn EM, Hunter K, Jing ZC, Johns R, Kaul S, Kawut SM, Lahm T, Leopold JA, Lewis GD, Mathai SC, McLaughlin VV, Michelakis ED, Nathan SD, Nichols W, Page G, Rabinovitch M, Rich J, Rischard F, Rounds S, Shah SJ, Tapson VF, Lowy N, Stockbridge N, Weinmann G, Xiao L.

Am J Respir Crit Care Med. 2017 Jun 15;195(12):1661-1670. doi: 10.1164/rccm.201701-0150WS.

25.

Response to Letter to the Editor on "Patient Reported Kneeling Ability in Fixed and Mobile Bearing Knee Arthroplasty".

Artz NJ, Hassaballa MA, Robinson JR, Newman JH, Porteous AJ, Murray JR.

J Arthroplasty. 2017 Jul;32(7):2316. doi: 10.1016/j.arth.2016.12.047. Epub 2017 Jan 20. No abstract available.

PMID:
28413141
26.

End-Tidal Carbon Dioxide as a Prognostic Feature in Pulmonary Arterial Hypertension.

Welch CE, Brittain EL, Newman AL, Robbins IM, Pugh ME, Newman JH, Hemnes AR.

Ann Am Thorac Soc. 2017 Jun;14(6):896-902. doi: 10.1513/AnnalsATS.201612-951OC.

27.

Clinical and Biological Insights Into Combined Post- and Pre-Capillary Pulmonary Hypertension.

Assad TR, Hemnes AR, Larkin EK, Glazer AM, Xu M, Wells QS, Farber-Eger EH, Sheng Q, Shyr Y, Harrell FE, Newman JH, Brittain EL.

J Am Coll Cardiol. 2016 Dec 13;68(23):2525-2536. doi: 10.1016/j.jacc.2016.09.942.

28.

Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.

Kohlhapp FJ, Huelsmann EJ, Lacek AT, Schenkel JM, Lusciks J, Broucek JR, Goldufsky JW, Hughes T, Zayas JP, Dolubizno H, Sowell RT, Kühner R, Burd S, Kubasiak JC, Nabatiyan A, Marshall S, Bommareddy PK, Li S, Newman JH, Monken CE, Shafikhani SH, Marzo AL, Guevara-Patino JA, Lasfar A, Thomas PG, Lattime EC, Kaufman HL, Zloza A.

Cell Rep. 2016 Oct 18;17(4):957-965. doi: 10.1016/j.celrep.2016.09.068.

29.

Hemodynamic evidence of vascular remodeling in combined post- and precapillary pulmonary hypertension.

Assad TR, Brittain EL, Wells QS, Farber-Eger EH, Halliday SJ, Doss LN, Xu M, Wang L, Harrell FE, Yu C, Robbins IM, Newman JH, Hemnes AR.

Pulm Circ. 2016 Sep;6(3):313-21. doi: 10.1086/688516.

30.

Survivorship and clinical outcome of the minimally invasive Uniglide medial fixed bearing, all-polyethylene tibia, unicompartmental knee arthroplasty at a mean follow-up of 7.3years.

Forster-Horváth C, Artz N, Hassaballa MA, Robinson JR, Porteous AJ, Murray JR, Newman JH.

Knee. 2016 Dec;23(6):981-986. doi: 10.1016/j.knee.2016.07.003. Epub 2016 Aug 6.

PMID:
27506988
31.

The Journey patellofemoral joint arthroplasty: A minimum 5year follow-up study.

Ahearn N, Metcalfe AJ, Hassaballa MA, Porteous AJ, Robinson JR, Murray JR, Newman JH.

Knee. 2016 Oct;23(5):900-4. doi: 10.1016/j.knee.2016.03.004. Epub 2016 Apr 28.

PMID:
27131405
32.

Compound heterozygote mutations in SPG7 in a family with adult-onset primary lateral sclerosis.

Yang Y, Zhang L, Lynch DR, Lukas T, Ahmeti K, Sleiman PM, Ryan E, Schadt KA, Newman JH, Deng HX, Siddique N, Siddique T.

Neurol Genet. 2016 Mar 3;2(2):e60. doi: 10.1212/NXG.0000000000000060. eCollection 2016 Apr.

33.

Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle.

Talati MH, Brittain EL, Fessel JP, Penner N, Atkinson J, Funke M, Grueter C, Jerome WG, Freeman M, Newman JH, West J, Hemnes AR.

Am J Respir Crit Care Med. 2016 Sep 15;194(6):719-28. doi: 10.1164/rccm.201507-1444OC.

34.

Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension.

Brittain EL, Talati M, Fessel JP, Zhu H, Penner N, Calcutt MW, West JD, Funke M, Lewis GD, Gerszten RE, Hamid R, Pugh ME, Austin ED, Newman JH, Hemnes AR.

Circulation. 2016 May 17;133(20):1936-44. doi: 10.1161/CIRCULATIONAHA.115.019351. Epub 2016 Mar 22.

35.

Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.

Hemnes AR, Zhao M, West J, Newman JH, Rich S, Archer SL, Robbins IM, Blackwell TS, Cogan J, Loyd JE, Zhao Z, Gaskill C, Jetter C, Kropski JA, Majka SM, Austin ED.

Am J Respir Crit Care Med. 2016 Aug 15;194(4):464-75. doi: 10.1164/rccm.201508-1678OC.

36.

Pollinator Competition as a Driver of Floral Divergence: An Experimental Test.

Temeles EJ, Newman JT, Newman JH, Cho SY, Mazzotta AR, Kress WJ.

PLoS One. 2016 Jan 27;11(1):e0146431. doi: 10.1371/journal.pone.0146431. eCollection 2016.

37.

The Diastolic Pressure Gradient Does Not-and Should Not-Predict Outcomes.

Brittain EL, Assad TR, Hemnes AR, Newman JH.

JACC Heart Fail. 2015 Oct;3(10):845. doi: 10.1016/j.jchf.2015.06.008. No abstract available.

38.

Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects.

Machado RD, Southgate L, Eichstaedt CA, Aldred MA, Austin ED, Best DH, Chung WK, Benjamin N, Elliott CG, Eyries M, Fischer C, Gräf S, Hinderhofer K, Humbert M, Keiles SB, Loyd JE, Morrell NW, Newman JH, Soubrier F, Trembath RC, Viales RR, Grünig E.

Hum Mutat. 2015 Dec;36(12):1113-27. doi: 10.1002/humu.22904. Epub 2015 Oct 12. Review.

39.

Patient Reported Kneeling Ability in Fixed and Mobile Bearing Knee Arthroplasty.

Artz NJ, Hassaballa MA, Robinson JR, Newman JH, Porteous AJ, Murray JR.

J Arthroplasty. 2015 Dec;30(12):2159-63. doi: 10.1016/j.arth.2015.06.063. Epub 2015 Jul 2.

PMID:
26362784
40.

Use of pulmonary arterial hypertension-approved therapy in the treatment of non-group 1 pulmonary hypertension at US referral centers.

Trammell AW, Pugh ME, Newman JH, Hemnes AR, Robbins IM.

Pulm Circ. 2015 Jun;5(2):356-63. doi: 10.1086/681264.

41.

Mutational Analysis of the Chlamydia muridarum Plasticity Zone.

Rajaram K, Giebel AM, Toh E, Hu S, Newman JH, Morrison SG, Kari L, Morrison RP, Nelson DE.

Infect Immun. 2015 Jul;83(7):2870-81. doi: 10.1128/IAI.00106-15. Epub 2015 May 4.

42.

Lungs at high-altitude: genomic insights into hypoxic responses.

Mishra A, Mohammad G, Norboo T, Newman JH, Pasha MA.

J Appl Physiol (1985). 2015 Jul 1;119(1):1-15. doi: 10.1152/japplphysiol.00513.2014. Epub 2015 Apr 24. Review.

43.

Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension.

Newman JH, Holt TN, Cogan JD, Womack B, Phillips JA 3rd, Li C, Kendall Z, Stenmark KR, Thomas MG, Brown RD, Riddle SR, West JD, Hamid R.

Nat Commun. 2015 Apr 15;6:6863. doi: 10.1038/ncomms7863.

44.

[Genetics and genomics of pulmonary arterial hypertension].

Soubrier F, Chung WK, Machado R, Grünig E, Aldred M, Geraci M, Loyd JE, Elliott CG, Trembath RC, Newman JH, Humbert M.

Turk Kardiyol Dern Ars. 2014 Oct;42 Suppl 1:17-28. Turkish.

45.

Variability in hemodynamic evaluation of pulmonary hypertension at large referral centers.

Pugh ME, Hemnes AR, Trammell A, Newman JH, Robbins IM.

Pulm Circ. 2014 Dec;4(4):679-84. doi: 10.1086/678514.

46.

The first annual Drug Discovery and Development Symposium for Pulmonary Hypertension.

Newman JH.

Pulm Circ. 2014 Dec;4(4):533-4. doi: 10.1086/679063. No abstract available.

47.

Giants in chest medicine: Richard W. Light, MD.

Newman JH.

Chest. 2014 Nov;146(5):1152-1154. doi: 10.1378/chest.14-0622. No abstract available.

PMID:
25367468
48.

Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension.

Hemnes AR, Trammell AW, Archer SL, Rich S, Yu C, Nian H, Penner N, Funke M, Wheeler L, Robbins IM, Austin ED, Newman JH, West J.

Circulation. 2015 Jan 27;131(4):401-9; discussion 409. doi: 10.1161/CIRCULATIONAHA.114.013317. Epub 2014 Oct 31.

49.

Effect of acute arteriolar vasodilation on capacitance and resistance in pulmonary arterial hypertension.

Newman JH, Brittain EL, Robbins IM, Hemnes AR.

Chest. 2015 Apr;147(4):1080-1085. doi: 10.1378/chest.14-1461.

50.

Fixed bearing lateral unicompartmental knee arthroplasty--short to midterm survivorship and knee scores for 101 prostheses.

Smith JR, Robinson JR, Porteous AJ, Murray JR, Hassaballa MA, Artz N, Newman JH.

Knee. 2014 Aug;21(4):843-7. doi: 10.1016/j.knee.2014.04.003. Epub 2014 Apr 13.

PMID:
24831525

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