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ALSgeneScanner: a pipeline for the analysis and interpretation of DNA sequencing data of ALS patients.

Iacoangeli A, Al Khleifat A, Sproviero W, Shatunov A, Jones AR, Opie-Martin S, Naselli E, Topp SD, Fogh I, Hodges A, Dobson RJ, Newhouse SJ, Al-Chalabi A.

Amyotroph Lateral Scler Frontotemporal Degener. 2019 Mar 5:1-9. doi: 10.1080/21678421.2018.1562553. [Epub ahead of print]


Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.

de Jong S, Diniz MJA, Saloma A, Gadelha A, Santoro ML, Ota VK, Noto C; Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Curtis C, Newhouse SJ, Patel H, Hall LS, O Reilly PF, Belangero SI, Bressan RA, Breen G.

Commun Biol. 2018 Oct 8;1:163. doi: 10.1038/s42003-018-0155-y. eCollection 2018.


Common ELIXIR Service for Researcher Authentication and Authorisation.

Linden M, Prochazka M, Lappalainen I, Bucik D, Vyskocil P, Kuba M, Silén S, Belmann P, Sczyrba A, Newhouse S, Matyska L, Nyrönen T.

F1000Res. 2018 Aug 6;7. pii: ELIXIR-1199. doi: 10.12688/f1000research.15161.1. eCollection 2018.


Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort.

Santoro ML, Ota V, de Jong S, Noto C, Spindola LM, Talarico F, Gouvea E, Lee SH, Moretti P, Curtis C, Patel H, Newhouse S, Carvalho CM, Gadelha A, Cordeiro Q, Bressan RA, Belangero SI, Breen G.

Transl Psychiatry. 2018 Aug 31;8(1):174. doi: 10.1038/s41398-018-0230-7.


Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies.

Fabbri C, Tansey KE, Perlis RH, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Breen G, Curtis C, Lee SH, Newhouse S, Patel H, O'Donovan M, Lewis G, Jenkins G, Weinshilboum RM, Farmer A, Aitchison KJ, Craig I, McGuffin P, Schruers K, Biernacka JM, Uher R, Lewis CM.

Eur Neuropsychopharmacol. 2018 Aug;28(8):945-954. doi: 10.1016/j.euroneuro.2018.05.009. Epub 2018 Jun 28.


Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain.

Carbajosa G, Malki K, Lawless N, Wang H, Ryder JW, Wozniak E, Wood K, Mein CA, Dobson RJB, Collier DA, O'Neill MJ, Hodges AK, Newhouse SJ.

Neurobiol Aging. 2018 Sep;69:151-166. doi: 10.1016/j.neurobiolaging.2018.04.019. Epub 2018 May 17.


Identification of new risk factors for rolandic epilepsy: CNV at Xp22.31 and alterations at cholinergic synapses.

Addis L, Sproviero W, Thomas SV, Caraballo RH, Newhouse SJ, Gomez K, Hughes E, Kinali M, McCormick D, Hannan S, Cossu S, Taylor J, Akman CI, Wolf SM, Mandelbaum DE, Gupta R, van der Spek RA, Pruna D, Pal DK.

J Med Genet. 2018 Sep;55(9):607-616. doi: 10.1136/jmedgenet-2018-105319. Epub 2018 May 22.


A genome-wide association study for extremely high intelligence.

Zabaneh D, Krapohl E, Gaspar HA, Curtis C, Lee SH, Patel H, Newhouse S, Wu HM, Simpson MA, Putallaz M, Lubinski D, Plomin R, Breen G.

Mol Psychiatry. 2018 May;23(5):1226-1232. doi: 10.1038/mp.2017.121. Epub 2017 Jul 4.


Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer.

Traylor M, Walker JL, Corrigan AA, Hernandez MA, Newhouse SJ, Folarin AA, Patel H, Ross PJ, Sanderson JD, Spicer J, Prescott NJ, Mathew CG, Marinaki AM, Lewis CM.

PLoS One. 2018 May 1;13(5):e0188911. doi: 10.1371/journal.pone.0188911. eCollection 2018.


g(HbF): a genetic model of fetal hemoglobin in sickle cell disease.

Gardner K, Fulford T, Silver N, Rooks H, Angelis N, Allman M, Nkya S, Makani J, Howard J, Kesse-Adu R, Rees DC, Stuart-Smith S, Yeghen T, Awogbade M, Sangeda RZ, Mgaya J, Patel H, Newhouse S, Menzel S, Thein SL.

Blood Adv. 2018 Feb 13;2(3):235-239. doi: 10.1182/bloodadvances.2017009811.


New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation.

Fabbri C, Tansey KE, Perlis RH, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Breen G, Curtis C, Sang-Hyuk L, Newhouse S, Patel H, Guipponi M, Perroud N, Bondolfi G, O'Donovan M, Lewis G, Biernacka JM, Weinshilboum RM, Farmer A, Aitchison KJ, Craig I, McGuffin P, Uher R, Lewis CM.

Pharmacogenomics J. 2018 May 22;18(3):413-421. doi: 10.1038/tpj.2017.44. Epub 2017 Nov 21.


Widespread covariation of early environmental exposures and trait-associated polygenic variation.

Krapohl E, Hannigan LJ, Pingault JB, Patel H, Kadeva N, Curtis C, Breen G, Newhouse SJ, Eley TC, O'Reilly PF, Plomin R.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11727-11732. doi: 10.1073/pnas.1707178114. Epub 2017 Oct 16.


Multi-polygenic score approach to trait prediction.

Krapohl E, Patel H, Newhouse S, Curtis CJ, von Stumm S, Dale PS, Zabaneh D, Breen G, O'Reilly PF, Plomin R.

Mol Psychiatry. 2018 May;23(5):1368-1374. doi: 10.1038/mp.2017.163. Epub 2017 Aug 8.


Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort.

Baker E, Iqbal E, Johnston C, Broadbent M, Shetty H, Stewart R, Howard R, Newhouse S, Khondoker M, Dobson RJB.

PLoS One. 2017 Jun 7;12(6):e0178562. doi: 10.1371/journal.pone.0178562. eCollection 2017.


Genetic and environmental risk factors for rheumatoid arthritis in a UK African ancestry population: the GENRA case-control study.

Traylor M, Curtis C, Patel H, Breen G, Hyuck Lee S, Xu X, Newhouse S, Dobson R, Steer S, Cope AP, Markus HS, Lewis CM, Scott IC.

Rheumatology (Oxford). 2017 Aug 1;56(8):1282-1292. doi: 10.1093/rheumatology/kex048.


Brain Transcriptome Sequencing of a Natural Model of Alzheimer's Disease.

Altimiras F, Uszczynska-Ratajczak B, Camara F, Vlasova A, Palumbo E, Newhouse S, Deacon RM, Farias LA, Hurley MJ, Loyola DE, Vásquez RA, Dobson R, Guigó R, Cogram P.

Front Aging Neurosci. 2017 Mar 20;9:64. doi: 10.3389/fnagi.2017.00064. eCollection 2017. No abstract available.


Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study.

Traylor M, Rutten-Jacobs L, Curtis C, Patel H, Breen G, Newhouse S, Lewis CM, Markus HS.

Neurol Genet. 2017 Mar 15;3(2):e142. doi: 10.1212/NXG.0000000000000142. eCollection 2017 Apr.


Mitochondrial genes are altered in blood early in Alzheimer's disease.

Lunnon K, Keohane A, Pidsley R, Newhouse S, Riddoch-Contreras J, Thubron EB, Devall M, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Schalkwyk L, Dobson R, Malik AN, Powell J, Lovestone S, Hodges A; AddNeuroMed Consortium.

Neurobiol Aging. 2017 May;53:36-47. doi: 10.1016/j.neurobiolaging.2016.12.029. Epub 2017 Jan 7.


Pharmacogenetics of antidepressant response: A polygenic approach.

García-González J, Tansey KE, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Žagar T, Czerski PM, Jerman B, Buttenschøn HN, Schulze TG, Zobel A, Farmer A, Aitchison KJ, Craig I, McGuffin P, Giupponi M, Perroud N, Bondolfi G, Evans D, O'Donovan M, Peters TJ, Wendland JR, Lewis G, Kapur S, Perlis R, Arolt V, Domschke K; Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium, Breen G, Curtis C, Sang-Hyuk L, Kan C, Newhouse S, Patel H, Baune BT, Uher R, Lewis CM, Fabbri C.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Apr 3;75:128-134. doi: 10.1016/j.pnpbp.2017.01.011. Epub 2017 Jan 31.


Genome-Wide Association of Heroin Dependence in Han Chinese.

Kalsi G, Euesden J, Coleman JR, Ducci F, Aliev F, Newhouse SJ, Liu X, Ma X, Wang Y, Collier DA, Asherson P, Li T, Breen G.

PLoS One. 2016 Dec 9;11(12):e0167388. doi: 10.1371/journal.pone.0167388. eCollection 2016.


Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid.

Voyle N, Patel H, Folarin A, Newhouse S, Johnston C, Visser PJ, Dobson RJ, Kiddle SJ; EDAR and DESCRIPA study groups and the Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2017;55(4):1417-1427. doi: 10.3233/JAD-160707.


An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis.

Vassos E, Di Forti M, Coleman J, Iyegbe C, Prata D, Euesden J, O'Reilly P, Curtis C, Kolliakou A, Patel H, Newhouse S, Traylor M, Ajnakina O, Mondelli V, Marques TR, Gardner-Sood P, Aitchison KJ, Powell J, Atakan Z, Greenwood KE, Smith S, Ismail K, Pariante C, Gaughran F, Dazzan P, Markus HS, David AS, Lewis CM, Murray RM, Breen G.

Biol Psychiatry. 2017 Mar 15;81(6):470-477. doi: 10.1016/j.biopsych.2016.06.028. Epub 2016 Aug 6.


Elevation of circulating serotonin improves calcium dynamics in the peripartum dairy cow.

Weaver SR, Prichard AP, Endres EL, Newhouse SA, Peters TL, Crump PM, Akins MS, Crenshaw TD, Bruckmaier RM, Hernandez LL.

J Endocrinol. 2016 Jul;230(1):105-23. doi: 10.1530/JOE-16-0038.


Clinical Conundrums: How Safe Is Exercise in Patients with Asthma and Is High-Flow Nasal Oxygen Useful in Respiratory Failure?

Gaw R, Yap C, Newhouse SM, Aiyappan V.

Am J Respir Crit Care Med. 2016 Sep 1;194(5):631-3. doi: 10.1164/rccm.201511-2214RR. No abstract available.


Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis.

Fogh I, Lin K, Tiloca C, Rooney J, Gellera C, Diekstra FP, Ratti A, Shatunov A, van Es MA, Proitsi P, Jones A, Sproviero W, Chiò A, McLaughlin RL, Sorarù G, Corrado L, Stahl D, Del Bo R, Cereda C, Castellotti B, Glass JD, Newhouse S, Dobson R, Smith BN, Topp S, van Rheenen W, Meininger V, Melki J, Morrison KE, Shaw PJ, Leigh PN, Andersen PM, Comi GP, Ticozzi N, Mazzini L, D'Alfonso S, Traynor BJ, Van Damme P, Robberecht W, Brown RH, Landers JE, Hardiman O, Lewis CM, van den Berg LH, Shaw CE, Veldink JH, Silani V, Al-Chalabi A, Powell J.

JAMA Neurol. 2016 Jul 1;73(7):812-20. doi: 10.1001/jamaneurol.2016.1114.


Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis.

de Jong S, Newhouse SJ, Patel H, Lee S, Dempster D, Curtis C, Paya-Cano J, Murphy D, Wilson CE, Horder J, Mendez MA, Asherson P, Rivera M, Costello H, Maltezos S, Whitwell S, Pitts M, Tye C, Ashwood KL, Bolton P, Curran S, McGuffin P, Dobson R, Breen G.

Br J Psychiatry. 2016 Sep;209(3):202-8. doi: 10.1192/bjp.bp.115.175471. Epub 2016 May 5.


Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.

Allen GI, Amoroso N, Anghel C, Balagurusamy V, Bare CJ, Beaton D, Bellotti R, Bennett DA, Boehme KL, Boutros PC, Caberlotto L, Caloian C, Campbell F, Chaibub Neto E, Chang YC, Chen B, Chen CY, Chien TY, Clark T, Das S, Davatzikos C, Deng J, Dillenberger D, Dobson RJ, Dong Q, Doshi J, Duma D, Errico R, Erus G, Everett E, Fardo DW, Friend SH, Fröhlich H, Gan J, St George-Hyslop P, Ghosh SS, Glaab E, Green RC, Guan Y, Hong MY, Huang C, Hwang J, Ibrahim J, Inglese P, Iyappan A, Jiang Q, Katsumata Y, Kauwe JS, Klein A, Kong D, Krause R, Lalonde E, Lauria M, Lee E, Lin X, Liu Z, Livingstone J, Logsdon BA, Lovestone S, Ma TW, Malhotra A, Mangravite LM, Maxwell TJ, Merrill E, Nagorski J, Namasivayam A, Narayan M, Naz M, Newhouse SJ, Norman TC, Nurtdinov RN, Oyang YJ, Pawitan Y, Peng S, Peters MA, Piccolo SR, Praveen P, Priami C, Sabelnykova VY, Senger P, Shen X, Simmons A, Sotiras A, Stolovitzky G, Tangaro S, Tateo A, Tung YA, Tustison NJ, Varol E, Vradenburg G, Weiner MW, Xiao G, Xie L, Xie Y, Xu J, Yang H, Zhan X, Zhou Y, Zhu F, Zhu H, Zhu S; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2016 Jun;12(6):645-53. doi: 10.1016/j.jalz.2016.02.006. Epub 2016 Apr 11.


A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's Disease Diagnosis.

Voyle N, Keohane A, Newhouse S, Lunnon K, Johnston C, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Hodges A, Kiddle S, Dobson RJ.

J Alzheimers Dis. 2016;49(3):659-69. doi: 10.3233/JAD-150440.


Quality control, imputation and analysis of genome-wide genotyping data from the Illumina HumanCoreExome microarray.

Coleman JR, Euesden J, Patel H, Folarin AA, Newhouse S, Breen G.

Brief Funct Genomics. 2016 Jul;15(4):298-304. doi: 10.1093/bfgp/elv037. Epub 2015 Oct 5.


Tract Based Spatial Statistic Reveals No Differences in White Matter Microstructural Organization between Carriers and Non-Carriers of the APOE ɛ4 and ɛ2 Alleles in Young Healthy Adolescents.

Dell'Acqua F, Khan W, Gottlieb N, Giampietro V, Ginestet C, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Lemaítre H, Nees F, Paus T, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Gallinat J, Westman E, Schumann G, Lovestone S, Simmons A; IMAGEN consortium (

J Alzheimers Dis. 2015;47(4):977-84. doi: 10.3233/JAD-140519.


No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease.

Chiam JT, Lunnon K, Voyle N, Proitsi P, Coppola G, Geschwind D, Nelson S, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Hodges A, Lovestone S, Newhouse S, Dobson RJ, Kiddle SJ, Sattlecker M.

J Alzheimers Dis. 2015;47(3):741-50. doi: 10.3233/JAD-150289.


A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease.

Khan W, Aguilar C, Kiddle SJ, Doyle O, Thambisetty M, Muehlboeck S, Sattlecker M, Newhouse S, Lovestone S, Dobson R, Giampietro V, Westman E, Simmons A; Alzheimer’s Disease Neuroimaging Initiative.

PLoS One. 2015 Aug 18;10(8):e0134368. doi: 10.1371/journal.pone.0134368. eCollection 2015.


Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes.

Kiddle SJ, Steves CJ, Mehta M, Simmons A, Xu X, Newhouse S, Sattlecker M, Ashton NJ, Bazenet C, Killick R, Adnan J, Westman E, Nelson S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Curtis C, Breen G, Williams SC, Lovestone S, Spector TD, Dobson RJ.

Transl Psychiatry. 2015 Jun 16;5:e584. doi: 10.1038/tp.2015.78.


Perceived Partner Responsiveness Mediates the Association Between Sexual and Marital Satisfaction: A Daily Diary Study in Newlywed Couples.

Gadassi R, Bar-Nahum LE, Newhouse S, Anderson R, Heiman JR, Rafaeli E, Janssen E.

Arch Sex Behav. 2016 Jan;45(1):109-20. doi: 10.1007/s10508-014-0448-2. Epub 2015 Feb 14.


Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts.

Khondoker M, Newhouse S, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Dobson R, Simmons A; AddNeuroMed consortium; Alzheimer's Disease Neuroimaging Initiative.

J Alzheimers Dis. 2015;45(3):851-64. doi: 10.3233/JAD-142214.


Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets.

Gross AL, Sherva R, Mukherjee S, Newhouse S, Kauwe JS, Munsie LM, Waterston LB, Bennett DA, Jones RN, Green RC, Crane PK; Alzheimer's Disease Neuroimaging Initiative; GENAROAD Consortium; AD Genetics Consortium.

Neuroepidemiology. 2014;43(3-4):194-205. doi: 10.1159/000367970. Epub 2014 Nov 13.


Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.

Proitsi P, Lupton MK, Velayudhan L, Newhouse S, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Kloszewska I, Soininen H, Mecocci P, Vellas B; Alzheimer's Disease Neuroimaging Initiative, Williams J; GERAD1 Consortium, Stewart R, Sham P, Lovestone S, Powell JF.

PLoS Med. 2014 Sep 16;11(9):e1001713. doi: 10.1371/journal.pmed.1001713. eCollection 2014 Sep.


Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease.

Proitsi P, Lupton MK, Velayudhan L, Hunter G, Newhouse S, Lin K, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Craig D, Todd S, Johnston JA, McGuinness B, Kloszewska I, Soininen H, Mecocci P, Vellas B, Passmore PA, Sims R, Williams J, Brayne C; Alzheimer's Disease Neuroimaging Initiative; GERAD1 Consortium, Stewart R, Sham P, Lovestone S, Powell JF.

Neurobiol Aging. 2014 Dec;35(12):2883.e3-2883.e10. doi: 10.1016/j.neurobiolaging.2014.07.023. Epub 2014 Jul 24.


Circulating Proteomic Signatures of Chronological Age.

Menni C, Kiddle SJ, Mangino M, Viñuela A, Psatha M, Steves C, Sattlecker M, Buil A, Newhouse S, Nelson S, Williams S, Voyle N, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Spector TD, Dobson R, Valdes AM.

J Gerontol A Biol Sci Med Sci. 2015 Jul;70(7):809-16. doi: 10.1093/gerona/glu121. Epub 2014 Aug 14.


Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment.

Whitfield DR, Vallortigara J, Alghamdi A, Howlett D, Hortobágyi T, Johnson M, Attems J, Newhouse S, Ballard C, Thomas AJ, O'Brien JT, Aarsland D, Francis PT.

Neurobiol Aging. 2014 Dec;35(12):2836-2844. doi: 10.1016/j.neurobiolaging.2014.06.015. Epub 2014 Jun 17.


Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, Bradford Y, Tarasov KV, Dörr M, Müller-Nurasyid M, Lahtinen AM, Nolte IM, Smith AV, Bis JC, Isaacs A, Newhouse SJ, Evans DS, Post WS, Waggott D, Lyytikäinen LP, Hicks AA, Eisele L, Ellinghaus D, Hayward C, Navarro P, Ulivi S, Tanaka T, Tester DJ, Chatel S, Gustafsson S, Kumari M, Morris RW, Naluai ÅT, Padmanabhan S, Kluttig A, Strohmer B, Panayiotou AG, Torres M, Knoflach M, Hubacek JA, Slowikowski K, Raychaudhuri S, Kumar RD, Harris TB, Launer LJ, Shuldiner AR, Alonso A, Bader JS, Ehret G, Huang H, Kao WH, Strait JB, Macfarlane PW, Brown M, Caulfield MJ, Samani NJ, Kronenberg F, Willeit J; CARe Consortium; COGENT Consortium, Smith JG, Greiser KH, Meyer Zu Schwabedissen H, Werdan K, Carella M, Zelante L, Heckbert SR, Psaty BM, Rotter JI, Kolcic I, Polašek O, Wright AF, Griffin M, Daly MJ; DCCT/EDIC, Arnar DO, Hólm H, Thorsteinsdottir U; eMERGE Consortium, Denny JC, Roden DM, Zuvich RL, Emilsson V, Plump AS, Larson MG, O'Donnell CJ, Yin X, Bobbo M, D'Adamo AP, Iorio A, Sinagra G, Carracedo A, Cummings SR, Nalls MA, Jula A, Kontula KK, Marjamaa A, Oikarinen L, Perola M, Porthan K, Erbel R, Hoffmann P, Jöckel KH, Kälsch H, Nöthen MM; HRGEN Consortium, den Hoed M, Loos RJ, Thelle DS, Gieger C, Meitinger T, Perz S, Peters A, Prucha H, Sinner MF, Waldenberger M, de Boer RA, Franke L, van der Vleuten PA, Beckmann BM, Martens E, Bardai A, Hofman N, Wilde AA, Behr ER, Dalageorgou C, Giudicessi JR, Medeiros-Domingo A, Barc J, Kyndt F, Probst V, Ghidoni A, Insolia R, Hamilton RM, Scherer SW, Brandimarto J, Margulies K, Moravec CE, del Greco M F, Fuchsberger C, O'Connell JR, Lee WK, Watt GC, Campbell H, Wild SH, El Mokhtari NE, Frey N, Asselbergs FW, Mateo Leach I, Navis G, van den Berg MP, van Veldhuisen DJ, Kellis M, Krijthe BP, Franco OH, Hofman A, Kors JA, Uitterlinden AG, Witteman JC, Kedenko L, Lamina C, Oostra BA, Abecasis GR, Lakatta EG, Mulas A, Orrú M, Schlessinger D, Uda M, Markus MR, Völker U, Snieder H, Spector TD, Ärnlöv J, Lind L, Sundström J, Syvänen AC, Kivimaki M, Kähönen M, Mononen N, Raitakari OT, Viikari JS, Adamkova V, Kiechl S, Brion M, Nicolaides AN, Paulweber B, Haerting J, Dominiczak AF, Nyberg F, Whincup PH, Hingorani AD, Schott JJ, Bezzina CR, Ingelsson E, Ferrucci L, Gasparini P, Wilson JF, Rudan I, Franke A, Mühleisen TW, Pramstaller PP, Lehtimäki TJ, Paterson AD, Parsa A, Liu Y, van Duijn CM, Siscovick DS, Gudnason V, Jamshidi Y, Salomaa V, Felix SB, Sanna S, Ritchie MD, Stricker BH, Stefansson K, Boyer LA, Cappola TP, Olsen JV, Lage K, Schwartz PJ, Kääb S, Chakravarti A, Ackerman MJ, Pfeufer A, de Bakker PI, Newton-Cheh C.

Nat Genet. 2014 Aug;46(8):826-36. doi: 10.1038/ng.3014. Epub 2014 Jun 22.


Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.

Sattlecker M, Kiddle SJ, Newhouse S, Proitsi P, Nelson S, Williams S, Johnston C, Killick R, Simmons A, Westman E, Hodges A, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S; AddNeuroMed Consortium, Dobson RJ.

Alzheimers Dement. 2014 Nov;10(6):724-34. doi: 10.1016/j.jalz.2013.09.016. Epub 2014 Apr 25.


Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations.

Corrigan A, Walker JL, Wickramasinghe S, Hernandez MA, Newhouse SJ, Folarin AA, Lewis CM, Sanderson JD, Spicer J, Marinaki AM.

Pharmacogenomics J. 2014 Oct;14(5):411-7. doi: 10.1038/tpj.2014.13. Epub 2014 Apr 15.


No differences in hippocampal volume between carriers and non-carriers of the ApoE ε4 and ε2 alleles in young healthy adolescents.

Khan W, Giampietro V, Ginestet C, Dell'Acqua F, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaître H, Nees F, Paus T, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Gallinat J, Westman E, Schumann G, Lovestone S, Simmons A; IMAGEN consortium.

J Alzheimers Dis. 2014;40(1):37-43. doi: 10.3233/JAD-131841.


Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study.

Kiddle SJ, Sattlecker M, Proitsi P, Simmons A, Westman E, Bazenet C, Nelson SK, Williams S, Hodges A, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Newhouse S, Lovestone S, Dobson RJ.

J Alzheimers Dis. 2014;38(3):515-31. doi: 10.3233/JAD-130380. Review.


Daily or weekly? The role of treatment frequency in the effectiveness of grammar treatment for children with specific language impairment.

Smith-Lock K, Leitão S, Lambert L, Prior P, Dunn A, Cronje J, Newhouse S, Nickels L.

Int J Speech Lang Pathol. 2013 Jun;15(3):255-67. doi: 10.3109/17549507.2013.777851. Epub 2013 Apr 16.


Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

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Am J Hum Genet. 2012 Nov 2;91(5):823-38. doi: 10.1016/j.ajhg.2012.08.032. Epub 2012 Oct 11.


Plasma based markers of [11C] PiB-PET brain amyloid burden.

Kiddle SJ, Thambisetty M, Simmons A, Riddoch-Contreras J, Hye A, Westman E, Pike I, Ward M, Johnston C, Lupton MK, Lunnon K, Soininen H, Kloszewska I, Tsolaki M, Vellas B, Mecocci P, Lovestone S, Newhouse S, Dobson R; Alzheimers Disease Neuroimaging Initiative.

PLoS One. 2012;7(9):e44260. doi: 10.1371/journal.pone.0044260. Epub 2012 Sep 24.


Screening for OPTN mutations in a cohort of British amyotrophic lateral sclerosis patients.

Johnson L, Miller JW, Gkazi AS, Vance C, Topp SD, Newhouse SJ, Al-Chalabi A, Smith BN, Shaw CE.

Neurobiol Aging. 2012 Dec;33(12):2948.e15-7. doi: 10.1016/j.neurobiolaging.2012.06.023. Epub 2012 Aug 11.


The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder.

Smith BN, Newhouse S, Shatunov A, Vance C, Topp S, Johnson L, Miller J, Lee Y, Troakes C, Scott KM, Jones A, Gray I, Wright J, Hortobágyi T, Al-Sarraj S, Rogelj B, Powell J, Lupton M, Lovestone S, Sapp PC, Weber M, Nestor PJ, Schelhaas HJ, Asbroek AA, Silani V, Gellera C, Taroni F, Ticozzi N, Van den Berg L, Veldink J, Van Damme P, Robberecht W, Shaw PJ, Kirby J, Pall H, Morrison KE, Morris A, de Belleroche J, Vianney de Jong JM, Baas F, Andersen PM, Landers J, Brown RH Jr, Weale ME, Al-Chalabi A, Shaw CE.

Eur J Hum Genet. 2013 Jan;21(1):102-8. doi: 10.1038/ejhg.2012.98. Epub 2012 Jun 13.

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