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Items: 14


Stem cell models of human synapse development and degeneration.

Wilson ES, Newell-Litwa K.

Mol Biol Cell. 2018 Nov 26;29(24):2913-2921. doi: 10.1091/mbc.E18-04-0222.


RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development.

Martin-Vilchez S, Whitmore L, Asmussen H, Zareno J, Horwitz R, Newell-Litwa K.

PLoS One. 2017 Jan 23;12(1):e0170464. doi: 10.1371/journal.pone.0170464. eCollection 2017.


Breaking down to build up: Neuroligin's C-terminal domain strengthens the synapse.

Newell-Litwa KA.

J Cell Biol. 2016 Feb 15;212(4):375-7. doi: 10.1083/jcb.201601081.


Non-muscle myosin II in disease: mechanisms and therapeutic opportunities.

Newell-Litwa KA, Horwitz R, Lamers ML.

Dis Model Mech. 2015 Dec;8(12):1495-515. doi: 10.1242/dmm.022103. Epub 2015 Nov 5. Review.


ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity.

Newell-Litwa KA, Badoual M, Asmussen H, Patel H, Whitmore L, Horwitz AR.

J Cell Biol. 2015 Jul 20;210(2):225-42. doi: 10.1083/jcb.201504046. Epub 2015 Jul 13.


Myosin IIb activity and phosphorylation status determines dendritic spine and post-synaptic density morphology.

Hodges JL, Newell-Litwa K, Asmussen H, Vicente-Manzanares M, Horwitz AR.

PLoS One. 2011;6(8):e24149. doi: 10.1371/journal.pone.0024149. Epub 2011 Aug 26.


Cell migration: PKA and RhoA set the pace.

Newell-Litwa KA, Horwitz AR.

Curr Biol. 2011 Aug 9;21(15):R596-8. doi: 10.1016/j.cub.2011.06.032.


Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells.

Vicente-Manzanares M, Newell-Litwa K, Bachir AI, Whitmore LA, Horwitz AR.

J Cell Biol. 2011 Apr 18;193(2):381-96. doi: 10.1083/jcb.201012159. Epub 2011 Apr 11.


Hermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampus.

Newell-Litwa K, Chintala S, Jenkins S, Pare JF, McGaha L, Smith Y, Faundez V.

J Neurosci. 2010 Jan 20;30(3):820-31. doi: 10.1523/JNEUROSCI.3400-09.2010.


Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles.

Newell-Litwa K, Salazar G, Smith Y, Faundez V.

Mol Biol Cell. 2009 Mar;20(5):1441-53. doi: 10.1091/mbc.E08-05-0456. Epub 2009 Jan 14.


Distinct roles of galactose-1P in galactose-mediated growth arrest of yeast deficient in galactose-1P uridylyltransferase (GALT) and UDP-galactose 4'-epimerase (GALE).

Mumma JO, Chhay JS, Ross KL, Eaton JS, Newell-Litwa KA, Fridovich-Keil JL.

Mol Genet Metab. 2008 Feb;93(2):160-71. Epub 2007 Nov 5.


The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3.

Berger AC, Salazar G, Styers ML, Newell-Litwa KA, Werner E, Maue RA, Corbett AH, Faundez V.

J Cell Sci. 2007 Oct 15;120(Pt 20):3640-52. Epub 2007 Sep 25.


Neuronal and non-neuronal functions of the AP-3 sorting machinery.

Newell-Litwa K, Seong E, Burmeister M, Faundez V.

J Cell Sci. 2007 Feb 15;120(Pt 4):531-41. Review.


BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes.

Salazar G, Craige B, Styers ML, Newell-Litwa KA, Doucette MM, Wainer BH, Falcon-Perez JM, Dell'Angelica EC, Peden AA, Werner E, Faundez V.

Mol Biol Cell. 2006 Sep;17(9):4014-26. Epub 2006 Jun 7.

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