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Items: 1 to 50 of 200

1.

Clinical activity of ceftazidime/avibactam against MDR Enterobacteriaceae and Pseudomonas aeruginosa: pooled data from the ceftazidime/avibactam Phase III clinical trial programme.

Stone GG, Newell P, Gasink LB, Broadhurst H, Wardman A, Yates K, Chen Z, Song J, Chow JW.

J Antimicrob Chemother. 2018 Jun 14. doi: 10.1093/jac/dky204. [Epub ahead of print]

PMID:
29912399
2.

In Vitro Activity of Ceftazidime-Avibactam against Isolates from Patients in a Phase 3 Clinical Trial for Treatment of Complicated Intra-abdominal Infections.

Stone GG, Newell P, Bradford PA.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e02584-17. doi: 10.1128/AAC.02584-17. Print 2018 Jul.

PMID:
29686147
3.

Avibactam Pharmacokinetic/Pharmacodynamic Targets.

Nichols WW, Newell P, Critchley IA, Riccobene T, Das S.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e02446-17. doi: 10.1128/AAC.02446-17. Print 2018 Jun. Review.

PMID:
29610208
4.

A Metagenome-Wide Association Study and Arrayed Mutant Library Confirm Acetobacter Lipopolysaccharide Genes Are Necessary for Association with Drosophila melanogaster.

White KM, Matthews MK, Hughes RC, Sommer AJ, Griffitts JS, Newell PD, Chaston JM.

G3 (Bethesda). 2018 Mar 28;8(4):1119-1127. doi: 10.1534/g3.117.300530.

5.

MAGNAMWAR: an R package for genome-wide association studies of bacterial orthologs.

Sexton CE, Smith HZ, Newell PD, Douglas AE, Chaston JM.

Bioinformatics. 2018 Jun 1;34(11):1951-1952. doi: 10.1093/bioinformatics/bty001.

PMID:
29342236
6.

Spatiotemporally Heterogeneous Population Dynamics of Gut Bacteria Inferred from Fecal Time Series Data.

Inamine H, Ellner SP, Newell PD, Luo Y, Buchon N, Douglas AE.

MBio. 2018 Jan 9;9(1). pii: e01453-17. doi: 10.1128/mBio.01453-17.

7.

Regional Metastatic Behavior of Nonfunctional Pancreatic Neuroendocrine Tumors: Impact of Lymph Node Positivity on Survival.

Jutric Z, Grendar J, Hoen HM, Cho SW, Cassera MA, Newell PH, Hammill CW, Hansen PD, Wolf RF.

Pancreas. 2017 Aug;46(7):898-903. doi: 10.1097/MPA.0000000000000861.

PMID:
28697130
8.

Draft Genome Sequence of Lactobacillus paracasei DmW181, a Bacterium Isolated from Wild Drosophila.

Hammer AJ, Walters A, Carroll C, Newell PD, Chaston JM.

Genome Announc. 2017 Jul 6;5(27). pii: e00545-17. doi: 10.1128/genomeA.00545-17.

9.

A genomic investigation of ecological differentiation between free-living and Drosophila-associated bacteria.

Winans NJ, Walter A, Chouaia B, Chaston JM, Douglas AE, Newell PD.

Mol Ecol. 2017 Sep;26(17):4536-4550. doi: 10.1111/mec.14232. Epub 2017 Jul 24.

PMID:
28667798
10.

Genome Sequence of Weissella cibaria DmW_103, Isolated from Wild Drosophila.

Ricks NJ, Carroll C, Walters A, Newell PD, Chaston JM.

Genome Announc. 2017 Jun 15;5(24). pii: e00512-17. doi: 10.1128/genomeA.00512-17.

11.

Genome Sequence of Leuconostoc citreum DmW_111, Isolated from Wild Drosophila.

Wright SM, Carroll C, Walters A, Newell PD, Chaston JM.

Genome Announc. 2017 Jun 15;5(24). pii: e00507-17. doi: 10.1128/genomeA.00507-17.

12.

Physiological responses of insects to microbial fermentation products: Insights from the interactions between Drosophila and acetic acid.

Kim G, Huang JH, McMullen JG 2nd, Newell PD, Douglas AE.

J Insect Physiol. 2018 Apr;106(Pt 1):13-19. doi: 10.1016/j.jinsphys.2017.05.005. Epub 2017 May 15.

PMID:
28522417
13.

Analysis of 340 Patients with Solid Pseudopapillary Tumors of the Pancreas: A Closer Look at Patients with Metastatic Disease.

Jutric Z, Rozenfeld Y, Grendar J, Hammill CW, Cassera MA, Newell PH, Hansen PD, Wolf RF.

Ann Surg Oncol. 2017 Jul;24(7):2015-2022. doi: 10.1245/s10434-017-5772-z. Epub 2017 Mar 15.

PMID:
28299507
14.

Validation of Fistula Risk Score calculator in diverse North American HPB practices.

Grendar J, Jutric Z, Leal JN, Ball CG, Bertens K, Dixon E, Hammill CW, Kastenberg Z, Newell PH, Rocha F, Visser B, Wolf RF, Hansen PD.

HPB (Oxford). 2017 Jun;19(6):508-514. doi: 10.1016/j.hpb.2017.01.021. Epub 2017 Feb 21.

15.

In vitro activity of ceftazidime/avibactam against urinary isolates from patients in a Phase 3 clinical trial programme for the treatment of complicated urinary tract infections.

Stone GG, Bradford PA, Yates K, Newell P.

J Antimicrob Chemother. 2017 May 1;72(5):1396-1399. doi: 10.1093/jac/dkw561.

PMID:
28088768
16.

Reply to Johnson.

Wagenlehner FM, Newell P, Yates K, Gasink LB.

Clin Infect Dis. 2017 Feb 1;64(3):391. doi: 10.1093/cid/ciw713. Epub 2016 Oct 24. No abstract available.

PMID:
27941118
17.
18.

Ceftazidime-avibactam in ceftazidime-resistant infections.

Carmeli Y, Armstrong J, Newell P, Stone G, Wardman A.

Lancet Infect Dis. 2016 Sep;16(9):997-998. doi: 10.1016/S1473-3099(16)30265-1. No abstract available.

PMID:
27684334
19.

Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy.

Crittenden MR, Baird J, Friedman D, Savage T, Uhde L, Alice A, Cottam B, Young K, Newell P, Nguyen C, Bambina S, Kramer G, Akporiaye E, Malecka A, Jackson A, Gough MJ.

Oncotarget. 2016 Nov 29;7(48):78653-78666. doi: 10.18632/oncotarget.11823.

20.

A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma.

Crocenzi T, Cottam B, Newell P, Wolf RF, Hansen PD, Hammill C, Solhjem MC, To YY, Greathouse A, Tormoen G, Jutric Z, Young K, Bahjat KS, Gough MJ, Crittenden MR.

J Immunother Cancer. 2016 Aug 16;4:45. doi: 10.1186/s40425-016-0149-6. eCollection 2016.

21.

Programmed cell death-1 blockade enhances response to stereotactic radiation in an orthotopic murine model of hepatocellular carcinoma.

Friedman D, Baird JR, Young KH, Cottam B, Crittenden MR, Friedman S, Gough MJ, Newell P.

Hepatol Res. 2017 Jun;47(7):702-714. doi: 10.1111/hepr.12789. Epub 2016 Sep 22.

PMID:
27501850
22.

Rearing the Fruit Fly Drosophila melanogaster Under Axenic and Gnotobiotic Conditions.

Koyle ML, Veloz M, Judd AM, Wong AC, Newell PD, Douglas AE, Chaston JM.

J Vis Exp. 2016 Jul 30;(113). doi: 10.3791/54219.

PMID:
27500374
23.

Ceftazidime-avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program.

Wagenlehner FM, Sobel JD, Newell P, Armstrong J, Huang X, Stone GG, Yates K, Gasink LB.

Clin Infect Dis. 2016 Sep 15;63(6):754-762. doi: 10.1093/cid/ciw378. Epub 2016 Jun 16.

24.

Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.

Young KH, Baird JR, Savage T, Cottam B, Friedman D, Bambina S, Messenheimer DJ, Fox B, Newell P, Bahjat KS, Gough MJ, Crittenden MR.

PLoS One. 2016 Jun 9;11(6):e0157164. doi: 10.1371/journal.pone.0157164. eCollection 2016.

25.
26.

Preoperative computed tomography scan to predict pancreatic fistula after distal pancreatectomy using gland and tumor characteristics.

Jutric Z, Johnston WC, Grendar J, Haykin L, Mathews C, Harmon LK, Shen J, Hahn HP, Coy DL, Cassera MA, Helton WS, Rocha FG, Wolf RF, Hansen PD, Hammill CW, Alseidi AA, Newell PH.

Am J Surg. 2016 May;211(5):871-6. doi: 10.1016/j.amjsurg.2016.02.001. Epub 2016 Feb 23.

PMID:
27046794
27.

Efficacy and Safety of Ceftazidime-Avibactam Plus Metronidazole Versus Meropenem in the Treatment of Complicated Intra-abdominal Infection: Results From a Randomized, Controlled, Double-Blind, Phase 3 Program.

Mazuski JE, Gasink LB, Armstrong J, Broadhurst H, Stone GG, Rank D, Llorens L, Newell P, Pachl J.

Clin Infect Dis. 2016 Jun 1;62(11):1380-1389. doi: 10.1093/cid/ciw133. Epub 2016 Mar 8.

29.

Impact of lymph node status in patients with intrahepatic cholangiocarcinoma treated by major hepatectomy: a review of the National Cancer Database.

Jutric Z, Johnston WC, Hoen HM, Newell PH, Cassera MA, Hammill CW, Wolf RF, Hansen PD.

HPB (Oxford). 2016 Jan;18(1):79-87. doi: 10.1016/j.hpb.2015.07.006.

30.

Total pancreatectomy for pancreatic ductal adenocarcinoma: review of the National Cancer Data Base.

Johnston WC, Hoen HM, Cassera MA, Newell PH, Hammill CW, Hansen PD, Wolf RF.

HPB (Oxford). 2016 Jan;18(1):21-8. doi: 10.1016/j.hpb.2015.07.009. Epub 2015 Dec 21. Review.

31.

Host Genetic Control of the Microbiota Mediates the Drosophila Nutritional Phenotype.

Chaston JM, Dobson AJ, Newell PD, Douglas AE.

Appl Environ Microbiol. 2015 Nov 13;82(2):671-9. doi: 10.1128/AEM.03301-15. Print 2016 Jan 15.

32.

Corrigendum: Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster.

Dobson AJ, Chaston JM, Newell PD, Donahue L, Hermann SL, Sannino DR, Westmiller S, Wong AC, Clark AG, Lazzaro BP, Douglas AE.

Nat Commun. 2015 May 15;6:7296. doi: 10.1038/ncomms8296. No abstract available.

PMID:
25976209
33.

Female gender and diabetes mellitus increase the risk of recurrence after laparoscopic incisional hernia repair.

Hornby ST, McDermott FD, Coleman M, Ahmed Z, Bunni J, Bunting D, Elshaer M, Evans V, Kimble A, Kostalas M, Page G, Singh J, Szczebiot L, Wienand-Barnett S, Wilkins A, Williams O, Newell P.

Ann R Coll Surg Engl. 2015 Mar;97(2):115-9. doi: 10.1308/003588414X14055925058751. Erratum in: Ann R Coll Surg Engl. 2016 Jan;98(1):iv. El-Shaer, M [corrected to Elshaer, M].

34.

Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster.

Dobson AJ, Chaston JM, Newell PD, Donahue L, Hermann SL, Sannino DR, Westmiller S, Wong AC, Clark AG, Lazzaro BP, Douglas AE.

Nat Commun. 2015 Feb 18;6:6312. doi: 10.1038/ncomms7312. Erratum in: Nat Commun. 2015;6:7296.

35.

Multimodal treatment of unresectable hepatocellular carcinoma to achieve complete response results in improved survival.

Newell PH, Wu Y, Hoen H, Uppal R, Thiesing JT, Sasadeusz K, Cassera MA, Wolf RF, Hansen P, Hammill CW.

HPB (Oxford). 2015 May;17(5):454-60. doi: 10.1111/hpb.12377. Epub 2015 Jan 12.

36.

Does a home treatment acute relapse prevention strategy reduce admissions for people with mania in bipolar affective disorder?

Murton C, Cooper M, Dinniss S, Roberts S, Booth N, Newell P.

Psychiatr Bull (2014). 2014 Dec;38(6):276-80. doi: 10.1192/pb.bp.113.044321.

37.

Detailed characterization of tumor infiltrating lymphocytes in two distinct human solid malignancies show phenotypic similarities.

Kovacsovics-Bankowski M, Chisholm L, Vercellini J, Tucker CG, Montler R, Haley D, Newell P, Ma J, Tseng P, Wolf R, Vetto JT, Hammill C, Hansen P, Weinberg AD.

J Immunother Cancer. 2014 Nov 18;2(1):38. doi: 10.1186/s40425-014-0038-9. eCollection 2014.

38.

In vivo function and comparative genomic analyses of the Drosophila gut microbiota identify candidate symbiosis factors.

Newell PD, Chaston JM, Wang Y, Winans NJ, Sannino DR, Wong AC, Dobson AJ, Kagle J, Douglas AE.

Front Microbiol. 2014 Nov 4;5:576. doi: 10.3389/fmicb.2014.00576. eCollection 2014.

39.

Metagenome-wide association of microbial determinants of host phenotype in Drosophila melanogaster.

Chaston JM, Newell PD, Douglas AE.

MBio. 2014 Sep 30;5(5):e01631-14. doi: 10.1128/mBio.01631-14.

40.

Root biomass production in populations of six rooted macrophytes in response to Cu exposure: intra-specific variability versus constitutive-like tolerance.

Marchand L, Nsanganwimana F, Lamy JB, Quintela-Sabaris C, Gonnelli C, Colzi I, Fletcher T, Oustrière N, Kolbas A, Kidd P, Bordas F, Newell P, Alvarenga P, Deletic A, Mench M.

Environ Pollut. 2014 Oct;193:205-215. doi: 10.1016/j.envpol.2014.07.001. Epub 2014 Jul 21.

PMID:
25058419
41.

TGFβ inhibition prior to hypofractionated radiation enhances efficacy in preclinical models.

Young KH, Newell P, Cottam B, Friedman D, Savage T, Baird JR, Akporiaye E, Gough MJ, Crittenden M.

Cancer Immunol Res. 2014 Oct;2(10):1011-22. doi: 10.1158/2326-6066.CIR-13-0207. Epub 2014 Jul 21.

42.

Expression of arginase I in myeloid cells limits control of residual disease after radiation therapy of tumors in mice.

Crittenden MR, Savage T, Cottam B, Baird J, Rodriguez PC, Newell P, Young K, Jackson AM, Gough MJ.

Radiat Res. 2014 Aug;182(2):182-90. doi: 10.1667/RR13493.1. Epub 2014 Jul 3.

PMID:
24992164
43.

Structural features of the Pseudomonas fluorescens biofilm adhesin LapA required for LapG-dependent cleavage, biofilm formation, and cell surface localization.

Boyd CD, Smith TJ, El-Kirat-Chatel S, Newell PD, Dufrêne YF, O'Toole GA.

J Bacteriol. 2014 Aug;196(15):2775-88. doi: 10.1128/JB.01629-14. Epub 2014 May 16.

44.

A Small-Group Activity Introducing the Use and Interpretation of BLAST.

Newell PD, Fricker AD, Roco CA, Chandrangsu P, Merkel SM.

J Microbiol Biol Educ. 2013 Dec 2;14(2):238-43. doi: 10.1128/jmbe.v14i2.637. eCollection 2013.

45.

Interspecies interactions determine the impact of the gut microbiota on nutrient allocation in Drosophila melanogaster.

Newell PD, Douglas AE.

Appl Environ Microbiol. 2014 Jan;80(2):788-96. doi: 10.1128/AEM.02742-13. Epub 2013 Nov 15.

46.

Neoadjuvant radiation therapy and its impact on complications after pancreaticoduodenectomy for pancreatic cancer: analysis of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP).

Cho SW, Tzeng CW, Johnston WC, Cassera MA, Newell PH, Hammill CW, Wolf RF, Aloia TA, Hansen PD.

HPB (Oxford). 2014 Apr;16(4):350-6. doi: 10.1111/hpb.12141. Epub 2013 Sep 24.

47.

β-Catenin signaling in hepatocellular cancer: Implications in inflammation, fibrosis, and proliferation.

Lee JM, Yang J, Newell P, Singh S, Parwani A, Friedman SL, Nejak-Bowen KN, Monga SP.

Cancer Lett. 2014 Feb 1;343(1):90-7. doi: 10.1016/j.canlet.2013.09.020. Epub 2013 Sep 23.

48.

Peak plasma anti-Xa levels after first and third doses of enoxaparin in women receiving weight-based thromboprophylaxis following caesarean section: a prospective cohort study.

Hiscock RJ, Casey E, Simmons SW, Walker SP, Newell PA.

Int J Obstet Anesth. 2013 Nov;22(4):280-8. doi: 10.1016/j.ijoa.2013.05.008. Epub 2013 Aug 16.

PMID:
23958275
49.

VEGF signaling in cancer treatment.

Sia D, Alsinet C, Newell P, Villanueva A.

Curr Pharm Des. 2014;20(17):2834-42. Review.

PMID:
23944367
50.

The peripheral myeloid expansion driven by murine cancer progression is reversed by radiation therapy of the tumor.

Crittenden MR, Savage T, Cottam B, Bahjat KS, Redmond WL, Bambina S, Kasiewicz M, Newell P, Jackson AM, Gough MJ.

PLoS One. 2013 Jul 25;8(7):e69527. doi: 10.1371/journal.pone.0069527. Print 2013.

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