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Items: 1 to 50 of 217


Why fossil fuel producer subsidies matter.

Erickson P, van Asselt H, Koplow D, Lazarus M, Newell P, Oreskes N, Supran G.

Nature. 2020 Feb;578(7793):E1-E4. doi: 10.1038/s41586-019-1920-x. Epub 2020 Feb 5. No abstract available.


Considerations in the Selection of Renal Dosage Adjustments for Patients with Serious Infections and Lessons Learned from the Development of Ceftazidime-Avibactam.

Li J, Lovern M, Riccobene T, Carrothers TJ, Newell P, Das S, Talley AK, Tawadrous M.

Antimicrob Agents Chemother. 2020 Mar 24;64(4). pii: e02105-19. doi: 10.1128/AAC.02105-19. Print 2020 Mar 24. Review.


Effect of Domain Size, Boundary, and Loading Conditions on Mechanical Properties of Amorphous Silica: A Reactive Molecular Dynamics Study.

Vo T, Reeder B, Damone A, Newell P.

Nanomaterials (Basel). 2019 Dec 25;10(1). pii: E54. doi: 10.3390/nano10010054.


The microbiota influences the Drosophila melanogaster life history strategy.

Walters AW, Hughes RC, Call TB, Walker CJ, Wilcox H, Petersen SC, Rudman SM, Newell PD, Douglas AE, Schmidt PS, Chaston JM.

Mol Ecol. 2020 Feb;29(3):639-653. doi: 10.1111/mec.15344. Epub 2020 Jan 3.


Selecting the dosage of ceftazidime-avibactam in the perfect storm of nosocomial pneumonia.

Das S, Zhou D, Nichols WW, Townsend A, Newell P, Li J.

Eur J Clin Pharmacol. 2020 Mar;76(3):349-361. doi: 10.1007/s00228-019-02804-z. Epub 2019 Dec 14. Review.


The microbiota of Drosophila suzukii influences the larval development of Drosophila melanogaster.

Solomon GM, Dodangoda H, McCarthy-Walker T, Ntim-Gyakari R, Newell PD.

PeerJ. 2019 Nov 19;7:e8097. doi: 10.7717/peerj.8097. eCollection 2019.


Safety and Efficacy of Ceftazidime-Avibactam in the Treatment of Children ≥3 Months to <18 Years With Complicated Urinary Tract Infection: Results from a Phase 2 Randomized, Controlled Trial.

Bradley JS, Roilides E, Broadhurst H, Cheng K, Huang LM, MasCasullo V, Newell P, Stone GG, Tawadrous M, Wajsbrot D, Yates K, Gardner A.

Pediatr Infect Dis J. 2019 Sep;38(9):920-928. doi: 10.1097/INF.0000000000002395.


Safety and Efficacy of Ceftazidime-Avibactam Plus Metronidazole in the Treatment of Children ≥3 Months to <18 Years With Complicated Intra-Abdominal Infection: Results From a Phase 2, Randomized, Controlled Trial.

Bradley JS, Broadhurst H, Cheng K, Mendez M, Newell P, Prchlik M, Stone GG, Talley AK, Tawadrous M, Wajsbrot D, Yates K, Zuzova A, Gardner A.

Pediatr Infect Dis J. 2019 Aug;38(8):816-824. doi: 10.1097/INF.0000000000002392.


Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma.

Gunderson AJ, Yamazaki T, McCarty K, Phillips M, Alice A, Bambina S, Zebertavage L, Friedman D, Cottam B, Newell P, Gough MJ, Crittenden MR, Van der Veken P, Young KH.

PLoS One. 2019 Feb 6;14(2):e0211117. doi: 10.1371/journal.pone.0211117. eCollection 2019.


Dose Selection and Validation for Ceftazidime-Avibactam in Adults with Complicated Intra-abdominal Infections, Complicated Urinary Tract Infections, and Nosocomial Pneumonia.

Das S, Li J, Riccobene T, Carrothers TJ, Newell P, Melnick D, Critchley IA, Stone GG, Nichols WW.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02187-18. doi: 10.1128/AAC.02187-18. Print 2019 Apr. Review.


Management of asymptomatic, well-differentiated PNETs: results of the Delphi consensus process of the Americas Hepato-Pancreato-Biliary Association.

Mansour JC, Chavin K, Morris-Stiff G, Warner SG, Cardona K, Fong ZV, Maker A, Libutti SK, Warren R, St Hill C, Celinski S, Newell P, Ly QP, Howe J, Coburn N.

HPB (Oxford). 2019 May;21(5):515-523. doi: 10.1016/j.hpb.2018.09.020. Epub 2018 Dec 5.


Does attending a Delphi consensus conference impact surgeon attitudes? Survey results from the Americas HepatoPancreatoBiliary Association consensus conference on small asymptomatic pancreatic neuroendocrine tumors.

Maker AV, Tran TB, Coburn N, Fong ZV, Cardona K, Newell P, Morris-Stiff G, Chavin K, Mansour J; members of the AHPBA Research Committee Consensus Conference.

HPB (Oxford). 2019 May;21(5):524-530. doi: 10.1016/j.hpb.2018.10.001. Epub 2018 Nov 13.


Metabolic Basis for Mutualism between Gut Bacteria and Its Impact on the Drosophila melanogaster Host.

Sommer AJ, Newell PD.

Appl Environ Microbiol. 2019 Jan 9;85(2). pii: e01882-18. doi: 10.1128/AEM.01882-18. Print 2019 Jan 15.


Association of Immunologic Markers With Survival in Upfront Resectable Pancreatic Cancer.

Tang ES, Newell PH, Wolf RF, Hansen PD, Cottam B, Ballesteros-Merino C, Gough MJ.

JAMA Surg. 2018 Nov 1;153(11):1055-1057. doi: 10.1001/jamasurg.2018.1757. No abstract available.


Ceftazidime-Avibactam Susceptibility Breakpoints against Enterobacteriaceae and Pseudomonas aeruginosa.

Nichols WW, Stone GG, Newell P, Broadhurst H, Wardman A, MacPherson M, Yates K, Riccobene T, Critchley IA, Das S.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e02590-17. doi: 10.1128/AAC.02590-17. Print 2018 Nov.


Population Pharmacokinetic Modelling of Ceftazidime and Avibactam in the Plasma and Epithelial Lining Fluid of Healthy Volunteers.

Dimelow R, Wright JG, MacPherson M, Newell P, Das S.

Drugs R D. 2018 Sep;18(3):221-230. doi: 10.1007/s40268-018-0241-0.


Clinical activity of ceftazidime/avibactam against MDR Enterobacteriaceae and Pseudomonas aeruginosa: pooled data from the ceftazidime/avibactam Phase III clinical trial programme.

Stone GG, Newell P, Gasink LB, Broadhurst H, Wardman A, Yates K, Chen Z, Song J, Chow JW.

J Antimicrob Chemother. 2018 Sep 1;73(9):2519-2523. doi: 10.1093/jac/dky204.


In Vitro Activity of Ceftazidime-Avibactam against Isolates from Patients in a Phase 3 Clinical Trial for Treatment of Complicated Intra-abdominal Infections.

Stone GG, Newell P, Bradford PA.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e02584-17. doi: 10.1128/AAC.02584-17. Print 2018 Jul.


Avibactam Pharmacokinetic/Pharmacodynamic Targets.

Nichols WW, Newell P, Critchley IA, Riccobene T, Das S.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e02446-17. doi: 10.1128/AAC.02446-17. Print 2018 Jun. Review.


A Metagenome-Wide Association Study and Arrayed Mutant Library Confirm Acetobacter Lipopolysaccharide Genes Are Necessary for Association with Drosophila melanogaster.

White KM, Matthews MK, Hughes RC, Sommer AJ, Griffitts JS, Newell PD, Chaston JM.

G3 (Bethesda). 2018 Mar 28;8(4):1119-1127. doi: 10.1534/g3.117.300530.


MAGNAMWAR: an R package for genome-wide association studies of bacterial orthologs.

Sexton CE, Smith HZ, Newell PD, Douglas AE, Chaston JM.

Bioinformatics. 2018 Jun 1;34(11):1951-1952. doi: 10.1093/bioinformatics/bty001.


Spatiotemporally Heterogeneous Population Dynamics of Gut Bacteria Inferred from Fecal Time Series Data.

Inamine H, Ellner SP, Newell PD, Luo Y, Buchon N, Douglas AE.

mBio. 2018 Jan 9;9(1). pii: e01453-17. doi: 10.1128/mBio.01453-17.


Regional Metastatic Behavior of Nonfunctional Pancreatic Neuroendocrine Tumors: Impact of Lymph Node Positivity on Survival.

Jutric Z, Grendar J, Hoen HM, Cho SW, Cassera MA, Newell PH, Hammill CW, Hansen PD, Wolf RF.

Pancreas. 2017 Aug;46(7):898-903. doi: 10.1097/MPA.0000000000000861.


Draft Genome Sequence of Lactobacillus paracasei DmW181, a Bacterium Isolated from Wild Drosophila.

Hammer AJ, Walters A, Carroll C, Newell PD, Chaston JM.

Genome Announc. 2017 Jul 6;5(27). pii: e00545-17. doi: 10.1128/genomeA.00545-17.


A genomic investigation of ecological differentiation between free-living and Drosophila-associated bacteria.

Winans NJ, Walter A, Chouaia B, Chaston JM, Douglas AE, Newell PD.

Mol Ecol. 2017 Sep;26(17):4536-4550. doi: 10.1111/mec.14232. Epub 2017 Jul 24.


Genome Sequence of Weissella cibaria DmW_103, Isolated from Wild Drosophila.

Ricks NJ, Carroll C, Walters A, Newell PD, Chaston JM.

Genome Announc. 2017 Jun 15;5(24). pii: e00512-17. doi: 10.1128/genomeA.00512-17.


Genome Sequence of Leuconostoc citreum DmW_111, Isolated from Wild Drosophila.

Wright SM, Carroll C, Walters A, Newell PD, Chaston JM.

Genome Announc. 2017 Jun 15;5(24). pii: e00507-17. doi: 10.1128/genomeA.00507-17.


Physiological responses of insects to microbial fermentation products: Insights from the interactions between Drosophila and acetic acid.

Kim G, Huang JH, McMullen JG 2nd, Newell PD, Douglas AE.

J Insect Physiol. 2018 Apr;106(Pt 1):13-19. doi: 10.1016/j.jinsphys.2017.05.005. Epub 2017 May 15.


Analysis of 340 Patients with Solid Pseudopapillary Tumors of the Pancreas: A Closer Look at Patients with Metastatic Disease.

Jutric Z, Rozenfeld Y, Grendar J, Hammill CW, Cassera MA, Newell PH, Hansen PD, Wolf RF.

Ann Surg Oncol. 2017 Jul;24(7):2015-2022. doi: 10.1245/s10434-017-5772-z. Epub 2017 Mar 15.


Validation of Fistula Risk Score calculator in diverse North American HPB practices.

Grendar J, Jutric Z, Leal JN, Ball CG, Bertens K, Dixon E, Hammill CW, Kastenberg Z, Newell PH, Rocha F, Visser B, Wolf RF, Hansen PD.

HPB (Oxford). 2017 Jun;19(6):508-514. doi: 10.1016/j.hpb.2017.01.021. Epub 2017 Feb 21.


Developing a liver cancer program in the nonacademic medical center.

Benner K, Flora K, Newell P.

Clin Liver Dis (Hoboken). 2017 Feb 3;9(1):25-28. doi: 10.1002/cld.616. eCollection 2017 Jan. Review. No abstract available.


In vitro activity of ceftazidime/avibactam against urinary isolates from patients in a Phase 3 clinical trial programme for the treatment of complicated urinary tract infections.

Stone GG, Bradford PA, Yates K, Newell P.

J Antimicrob Chemother. 2017 May 1;72(5):1396-1399. doi: 10.1093/jac/dkw561.


Reply to Johnson.

Wagenlehner FM, Newell P, Yates K, Gasink LB.

Clin Infect Dis. 2017 Feb 1;64(3):391. doi: 10.1093/cid/ciw713. Epub 2016 Oct 24. No abstract available.


Ceftazidime-avibactam in ceftazidime-resistant infections.

Carmeli Y, Armstrong J, Newell P, Stone G, Wardman A.

Lancet Infect Dis. 2016 Sep;16(9):997-998. doi: 10.1016/S1473-3099(16)30265-1. No abstract available.


Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy.

Crittenden MR, Baird J, Friedman D, Savage T, Uhde L, Alice A, Cottam B, Young K, Newell P, Nguyen C, Bambina S, Kramer G, Akporiaye E, Malecka A, Jackson A, Gough MJ.

Oncotarget. 2016 Nov 29;7(48):78653-78666. doi: 10.18632/oncotarget.11823.


A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma.

Crocenzi T, Cottam B, Newell P, Wolf RF, Hansen PD, Hammill C, Solhjem MC, To YY, Greathouse A, Tormoen G, Jutric Z, Young K, Bahjat KS, Gough MJ, Crittenden MR.

J Immunother Cancer. 2016 Aug 16;4:45. doi: 10.1186/s40425-016-0149-6. eCollection 2016.


Programmed cell death-1 blockade enhances response to stereotactic radiation in an orthotopic murine model of hepatocellular carcinoma.

Friedman D, Baird JR, Young KH, Cottam B, Crittenden MR, Friedman S, Gough MJ, Newell P.

Hepatol Res. 2017 Jun;47(7):702-714. doi: 10.1111/hepr.12789. Epub 2016 Sep 22.


Rearing the Fruit Fly Drosophila melanogaster Under Axenic and Gnotobiotic Conditions.

Koyle ML, Veloz M, Judd AM, Wong AC, Newell PD, Douglas AE, Chaston JM.

J Vis Exp. 2016 Jul 30;(113). doi: 10.3791/54219.


Ceftazidime-avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program.

Wagenlehner FM, Sobel JD, Newell P, Armstrong J, Huang X, Stone GG, Yates K, Gasink LB.

Clin Infect Dis. 2016 Sep 15;63(6):754-762. doi: 10.1093/cid/ciw378. Epub 2016 Jun 16.


Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.

Young KH, Baird JR, Savage T, Cottam B, Friedman D, Bambina S, Messenheimer DJ, Fox B, Newell P, Bahjat KS, Gough MJ, Crittenden MR.

PLoS One. 2016 Jun 9;11(6):e0157164. doi: 10.1371/journal.pone.0157164. eCollection 2016.


Preoperative computed tomography scan to predict pancreatic fistula after distal pancreatectomy using gland and tumor characteristics.

Jutric Z, Johnston WC, Grendar J, Haykin L, Mathews C, Harmon LK, Shen J, Hahn HP, Coy DL, Cassera MA, Helton WS, Rocha FG, Wolf RF, Hansen PD, Hammill CW, Alseidi AA, Newell PH.

Am J Surg. 2016 May;211(5):871-6. doi: 10.1016/j.amjsurg.2016.02.001. Epub 2016 Feb 23.


Efficacy and Safety of Ceftazidime-Avibactam Plus Metronidazole Versus Meropenem in the Treatment of Complicated Intra-abdominal Infection: Results From a Randomized, Controlled, Double-Blind, Phase 3 Program.

Mazuski JE, Gasink LB, Armstrong J, Broadhurst H, Stone GG, Rank D, Llorens L, Newell P, Pachl J.

Clin Infect Dis. 2016 Jun 1;62(11):1380-1389. doi: 10.1093/cid/ciw133. Epub 2016 Mar 8.


Impact of lymph node status in patients with intrahepatic cholangiocarcinoma treated by major hepatectomy: a review of the National Cancer Database.

Jutric Z, Johnston WC, Hoen HM, Newell PH, Cassera MA, Hammill CW, Wolf RF, Hansen PD.

HPB (Oxford). 2016 Jan;18(1):79-87. doi: 10.1016/j.hpb.2015.07.006.


Total pancreatectomy for pancreatic ductal adenocarcinoma: review of the National Cancer Data Base.

Johnston WC, Hoen HM, Cassera MA, Newell PH, Hammill CW, Hansen PD, Wolf RF.

HPB (Oxford). 2016 Jan;18(1):21-8. doi: 10.1016/j.hpb.2015.07.009. Epub 2015 Dec 21. Review.


Host Genetic Control of the Microbiota Mediates the Drosophila Nutritional Phenotype.

Chaston JM, Dobson AJ, Newell PD, Douglas AE.

Appl Environ Microbiol. 2015 Nov 13;82(2):671-9. doi: 10.1128/AEM.03301-15. Print 2016 Jan 15.


Corrigendum: Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster.

Dobson AJ, Chaston JM, Newell PD, Donahue L, Hermann SL, Sannino DR, Westmiller S, Wong AC, Clark AG, Lazzaro BP, Douglas AE.

Nat Commun. 2015 May 15;6:7296. doi: 10.1038/ncomms8296. No abstract available.


Female gender and diabetes mellitus increase the risk of recurrence after laparoscopic incisional hernia repair.

Hornby ST, McDermott FD, Coleman M, Ahmed Z, Bunni J, Bunting D, Elshaer M, Evans V, Kimble A, Kostalas M, Page G, Singh J, Szczebiot L, Wienand-Barnett S, Wilkins A, Williams O, Newell P.

Ann R Coll Surg Engl. 2015 Mar;97(2):115-9. doi: 10.1308/003588414X14055925058751. Erratum in: Ann R Coll Surg Engl. 2016 Jan;98(1):iv. El-Shaer, M [corrected to Elshaer, M].

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