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Items: 1 to 50 of 714

1.

Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4.

Myers SM, Miller DC, Molyneux L, Arasta M, Bawn RH, Blackburn TJ, Cook SJ, Edwards N, Endicott JA, Golding BT, Griffin RJ, Hammonds T, Hardcastle IR, Harnor SJ, Heptinstall AB, Lochhead PA, Martin MP, Martin NC, Newell DR, Owen PJ, Pang LC, Reuillon T, Rigoreau LJM, Thomas HD, Tucker JA, Wang LZ, Wong AC, Noble MEM, Wedge SR, Cano C.

Eur J Med Chem. 2019 Sep 15;178:530-543. doi: 10.1016/j.ejmech.2019.05.057. Epub 2019 May 25.

PMID:
31212132
2.

Gamma Band Light Stimulation in Human Case Studies: Groundwork for Potential Alzheimer's Disease Treatment.

Jones M, McDermott B, Oliveira BL, O'Brien A, Coogan D, Lang M, Moriarty N, Dowd E, Quinlan L, Mc Ginley B, Dunne E, Newell D, Porter E, Elahi MA, O' Halloran M, Shahzad A.

J Alzheimers Dis. 2019;70(1):171-185. doi: 10.3233/JAD-190299.

PMID:
31156180
3.

Gateless and reversible carrier density tunability in epitaxial graphene devices functionalized with chromium tricarbonyl.

Rigosi AF, Kruskopf M, Hill HM, Jin H, Wu BY, Johnson PE, Zhang S, Berilla M, Hight Walker AR, Hacker CA, Newell DB, Elmquist RE.

Carbon N Y. 2019;142. doi: 10.1016/j.carbon.2018.10.085.

PMID:
31097837
4.

The shape of chiropractic in Europe: a cross sectional survey of chiropractor's beliefs and practice.

Gíslason HF, Salminen JK, Sandhaugen L, Storbråten AS, Versloot R, Roug I, Newell D.

Chiropr Man Therap. 2019 Apr 10;27:16. doi: 10.1186/s12998-019-0237-z. eCollection 2019.

5.

Glucocorticoids and selumetinib are highly synergistic in RAS pathway mutated childhood acute lymphoblastic leukemia through upregulation of BIM.

Matheson EC, Thomas H, Case M, Blair H, Jackson RK, Masic D, Veal G, Halsey C, Newell DR, Vormoor J, Irving JAE.

Haematologica. 2019 Jan 17. pii: haematol.2017.185975. doi: 10.3324/haematol.2017.185975. [Epub ahead of print]

6.

Chiropractors' views on the use of patient-reported outcome measures in clinical practice: a qualitative study.

Holmes MM, Bishop FL, Newell D, Field J, Lewith G.

Chiropr Man Therap. 2018 Dec 18;26:50. doi: 10.1186/s12998-018-0219-6. eCollection 2018.

7.

Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma.

Chen L, Pastorino F, Berry P, Bonner J, Kirk C, Wood KM, Thomas HD, Zhao Y, Daga A, Veal GJ, Lunec J, Newell DR, Ponzoni M, Tweddle DA.

Int J Cancer. 2019 Jun 15;144(12):3146-3159. doi: 10.1002/ijc.32058. Epub 2019 Jan 9.

8.

Review of the Amphibian Immune Response to Chytridiomycosis, and Future Directions.

Grogan LF, Robert J, Berger L, Skerratt LF, Scheele BC, Castley JG, Newell DA, McCallum HI.

Front Immunol. 2018 Nov 9;9:2536. doi: 10.3389/fimmu.2018.02536. eCollection 2018. Review.

9.

Towards epitaxial graphene p-n junctions as electrically programmable quantum resistance standards.

Hu J, Rigosi AF, Kruskopf M, Yang Y, Wu BY, Tian J, Panna AR, Lee HY, Payagala SU, Jones GR, Kraft ME, Jarrett DG, Watanabe K, Taniguchi T, Elmquist RE, Newell DB.

Sci Rep. 2018 Oct 9;8(1):15018. doi: 10.1038/s41598-018-33466-z.

10.

Quantum Hall device data monitoring following encapsulating polymer deposition.

Rigosi AF, Liu CI, Wu BY, Lee HY, Kruskopf M, Yang Y, Hill HM, Hu J, Bittle EG, Obrzut J, Hight Walker AR, Elmquist RE, Newell DB.

Data Brief. 2018 Aug 30;20:1201-1208. doi: 10.1016/j.dib.2018.08.121. eCollection 2018 Oct.

11.

Clinical, Social, and Neuropsychological Dimensions of the Intersection of Addiction and Criminality.

Nestor PG, Woodhull A, Newell D, O'Donovan K, Forte M, Harding S, Pomplun M.

J Am Acad Psychiatry Law. 2018 Jun;46(2):179-186. doi: 10.29158/JAAPL.003745-18.

PMID:
30026396
12.

Examining epitaxial graphene surface conductivity and quantum Hall device stability with Parylene passivation.

Rigosi AF, Liu CI, Wu BY, Lee HY, Kruskopf M, Yang Y, Hill HM, Hu J, Bittle EG, Obrzut J, Hight Walker AR, Elmquist RE, Newell DB.

Microelectron Eng. 2018 Jul;194:51-55. doi: 10.1016/j.mee.2018.03.004. Epub 2018 Mar 14.

13.

Highly Potent Clickable Probe for Cellular Imaging of MDM2 and Assessing Dynamic Responses to MDM2-p53 Inhibition.

Lebraud H, Noble RA, Phillips N, Heam K, Castro J, Zhao Y, Newell DR, Lunec J, Wedge SR, Heightman TD.

Bioconjug Chem. 2018 Jun 20;29(6):2100-2106. doi: 10.1021/acs.bioconjchem.8b00315. Epub 2018 Jun 12.

PMID:
29851469
14.

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.

Orengo JM, Radin AR, Kamat V, Badithe A, Ben LH, Bennett BL, Zhong S, Birchard D, Limnander A, Rafique A, Bautista J, Kostic A, Newell D, Duan X, Franklin MC, Olson W, Huang T, Gandhi NA, Lipsich L, Stahl N, Papadopoulos NJ, Murphy AJ, Yancopoulos GD.

Nat Commun. 2018 Apr 12;9(1):1421. doi: 10.1038/s41467-018-03636-8.

15.

Measuring the dielectric and optical response of millimeter-scale amorphous and hexagonal boron nitride films grown on epitaxial graphene.

Rigosi AF, Hill HM, Glavin NR, Pookpanratana SJ, Yang Y, Boosalis AG, Hu J, Rice A, Allerman AA, Nguyen NV, Hacker CA, Elmquist RE, Hight Walker AR, Newell DB.

2d Mater. 2018 Jan;5(1). pii: 011011. doi: 10.1088/2053-1583/aa9ea3. Epub 2017 Dec 13.

16.

Probing the dielectric response of the interfacial buffer layer in epitaxial graphene via optical spectroscopy.

Hill HM, Rigosi AF, Chowdhury S, Yang Y, Nguyen NV, Tavazza F, Elmquist RE, Newell DB, Hight Walker AR.

Phys Rev B. 2017 Nov;96(19). pii: 195437. doi: 10.1103/PhysRevB.96.195437. Epub 2017 Nov 28.

17.

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2.

Vormoor B, Schlosser YT, Blair H, Sharma A, Wilkinson S, Newell DR, Curtin N.

Oncotarget. 2017 Sep 28;8(69):113418-113430. doi: 10.18632/oncotarget.21300. eCollection 2017 Dec 26.

18.

Enterohaemorrhagic and other Shiga toxin-producing Escherichia coli (STEC): Where are we now regarding diagnostics and control strategies?

Newell DG, La Ragione RM.

Transbound Emerg Dis. 2018 May;65 Suppl 1:49-71. doi: 10.1111/tbed.12789. Epub 2018 Jan 25. Review.

PMID:
29369531
19.

Engagement as predictors of performance in a single cohort of undergraduate chiropractic students.

Rix J, Dewhurst P, Cooke C, Newell D.

J Chiropr Educ. 2017 Mar;32(1):36-42. doi: 10.7899/JCE-17-8. Epub 2018 Jan 13.

20.

Graphene Devices for Tabletop and High-Current Quantized Hall Resistance Standards.

Rigosi AF, Panna AR, Payagala SU, Kruskopf M, Kraft ME, Jones GR, Wu BY, Lee HY, Yang Y, Hu J, Jarrett DG, Newell DB, Elmquist RE.

IEEE Trans Instrum Meas. 2018;68. doi: 10.1109/TIM.2018.2882958.

21.

Confocal laser scanning microscopy for rapid optical characterization of graphene.

Panchal V, Yang Y, Cheng G, Hu J, Kruskopf M, Liu CI, Rigosi AF, Melios C, Hight Walker AR, Newell DB, Kazakova O, Elmquist RE.

Commun Phys. 2018;1. doi: 10.1038/s42005-018-0084-6.

22.

Quantum transport in graphene p-n junctions with moiré superlattice modulation.

Hu J, Rigosi AF, Lee JU, Lee HY, Yang Y, Liu CI, Elmquist RE, Newell DB.

Phys Rev B. 2018;98. doi: 10.1103/PhysRevB.98.045412.

23.

Comprehensive optical characterization of atomically thin NbSe2.

Hill HM, Rigosi AF, Krylyuk S, Tian J, Nguyen NV, Davydov AV, Newell DB, Walker ARH.

Phys Rev B. 2018;98. doi: 10.1103/PhysRevB.98.165109.

24.

Preoperative relative cerebral blood volume analysis in gliomas predicts survival and mitigates risk of biopsy sampling error.

McCullough BJ, Ader V, Aguedan B, Feng X, Susanto D, Benkers TL, Henson JW, Mayberg M, Cobbs CS, Gwinn RP, Monteith SJ, Newell DW, Delashaw J Jr, Fouke SJ, Rostad S, Keogh BP.

J Neurooncol. 2018 Jan;136(1):181-188. doi: 10.1007/s11060-017-2642-2. Epub 2017 Nov 2.

PMID:
29098571
25.

Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group.

Kelly S, Jahanshad N, Zalesky A, Kochunov P, Agartz I, Alloza C, Andreassen OA, Arango C, Banaj N, Bouix S, Bousman CA, Brouwer RM, Bruggemann J, Bustillo J, Cahn W, Calhoun V, Cannon D, Carr V, Catts S, Chen J, Chen JX, Chen X, Chiapponi C, Cho KK, Ciullo V, Corvin AS, Crespo-Facorro B, Cropley V, De Rossi P, Diaz-Caneja CM, Dickie EW, Ehrlich S, Fan FM, Faskowitz J, Fatouros-Bergman H, Flyckt L, Ford JM, Fouche JP, Fukunaga M, Gill M, Glahn DC, Gollub R, Goudzwaard ED, Guo H, Gur RE, Gur RC, Gurholt TP, Hashimoto R, Hatton SN, Henskens FA, Hibar DP, Hickie IB, Hong LE, Horacek J, Howells FM, Hulshoff Pol HE, Hyde CL, Isaev D, Jablensky A, Jansen PR, Janssen J, Jönsson EG, Jung LA, Kahn RS, Kikinis Z, Liu K, Klauser P, Knöchel C, Kubicki M, Lagopoulos J, Langen C, Lawrie S, Lenroot RK, Lim KO, Lopez-Jaramillo C, Lyall A, Magnotta V, Mandl RCW, Mathalon DH, McCarley RW, McCarthy-Jones S, McDonald C, McEwen S, McIntosh A, Melicher T, Mesholam-Gately RI, Michie PT, Mowry B, Mueller BA, Newell DT, O'Donnell P, Oertel-Knöchel V, Oestreich L, Paciga SA, Pantelis C, Pasternak O, Pearlson G, Pellicano GR, Pereira A, Pineda Zapata J, Piras F, Potkin SG, Preda A, Rasser PE, Roalf DR, Roiz R, Roos A, Rotenberg D, Satterthwaite TD, Savadjiev P, Schall U, Scott RJ, Seal ML, Seidman LJ, Shannon Weickert C, Whelan CD, Shenton ME, Kwon JS, Spalletta G, Spaniel F, Sprooten E, Stäblein M, Stein DJ, Sundram S, Tan Y, Tan S, Tang S, Temmingh HS, Westlye LT, Tønnesen S, Tordesillas-Gutierrez D, Doan NT, Vaidya J, van Haren NEM, Vargas CD, Vecchio D, Velakoulis D, Voineskos A, Voyvodic JQ, Wang Z, Wan P, Wei D, Weickert TW, Whalley H, White T, Whitford TJ, Wojcik JD, Xiang H, Xie Z, Yamamori H, Yang F, Yao N, Zhang G, Zhao J, van Erp TGM, Turner J, Thompson PM, Donohoe G.

Mol Psychiatry. 2018 May;23(5):1261-1269. doi: 10.1038/mp.2017.170. Epub 2017 Oct 17.

26.

Variability in Strength, Pain, and Disability Changes in Response to an Isolated Lumbar Extension Resistance Training Intervention in Participants with Chronic Low Back Pain.

Steele J, Fisher J, Bruce-Low S, Smith D, Osborne N, Newell D.

Healthcare (Basel). 2017 Oct 16;5(4). pii: E75. doi: 10.3390/healthcare5040075.

27.

Electrical Stabilization of Surface Resistivity in Epitaxial Graphene Systems by Amorphous Boron Nitride Encapsulation.

Rigosi AF, Liu CI, Glavin NR, Yang Y, Hill HM, Hu J, Hight Walker AR, Richter CA, Elmquist RE, Newell DB.

ACS Omega. 2017;2(5):2326-2332. doi: 10.1021/acsomega.7b00341. Epub 2017 May 25.

28.

Preservation of Surface Conductivity and Dielectric Loss Tangent in Large-Scale, Encapsulated Epitaxial Graphene Measured by Noncontact Microwave Cavity Perturbations.

Rigosi AF, Glavin NR, Liu CI, Yang Y, Obrzut J, Hill HM, Hu J, Lee HY, Hight Walker AR, Richter CA, Elmquist RE, Newell DB.

Small. 2017 Jul;13(26). doi: 10.1002/smll.201700452. Epub 2017 May 19.

29.

PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS.

Almeida GS, Bawn CM, Galler M, Wilson I, Thomas HD, Kyle S, Curtin NJ, Newell DR, Maxwell RJ.

NMR Biomed. 2017 Sep;30(9). doi: 10.1002/nbm.3736. Epub 2017 May 22.

PMID:
28543772
30.

Greater extracellular free-water in first-episode psychosis predicts better neurocognitive functioning.

Lyall AE, Pasternak O, Robinson DG, Newell D, Trampush JW, Gallego JA, Fava M, Malhotra AK, Karlsgodt KH, Kubicki M, Szeszko PR.

Mol Psychiatry. 2018 Mar;23(3):701-707. doi: 10.1038/mp.2017.43. Epub 2017 Mar 28.

31.

Childhood adversity associated with white matter alteration in the corpus callosum, corona radiata, and uncinate fasciculus of psychiatrically healthy adults.

McCarthy-Jones S, Oestreich LKL, Lyall AE, Kikinis Z, Newell DT, Savadjiev P, Shenton ME, Kubicki M, Pasternak O, Whitford TJ; Australian Schizophrenia Research Bank.

Brain Imaging Behav. 2018 Apr;12(2):449-458. doi: 10.1007/s11682-017-9703-1.

32.

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor.

Perera TPS, Jovcheva E, Mevellec L, Vialard J, De Lange D, Verhulst T, Paulussen C, Van De Ven K, King P, Freyne E, Rees DC, Squires M, Saxty G, Page M, Murray CW, Gilissen R, Ward G, Thompson NT, Newell DR, Cheng N, Xie L, Yang J, Platero SJ, Karkera JD, Moy C, Angibaud P, Laquerre S, Lorenzi MV.

Mol Cancer Ther. 2017 Jun;16(6):1010-1020. doi: 10.1158/1535-7163.MCT-16-0589. Epub 2017 Mar 24.

33.

Posterior arch C-1 screw technique: a cadaveric comparison study.

Moisi M, Fisahn C, Tkachenko L, Jeyamohan S, Reintjes S, Grunert P, Norvell DC, Tubbs RS, Page J, Newell DW, Nora P, Oskouian RJ, Chapman J.

J Neurosurg Spine. 2017 Jun;26(6):679-683. doi: 10.3171/2016.11.SPINE16769. Epub 2017 Mar 17.

PMID:
28304240
34.

Contextually Aided Recovery (CARe): a scientific theory for innate healing.

Newell D, Lothe LR, Raven TJL.

Chiropr Man Therap. 2017 Feb 13;25:6. doi: 10.1186/s12998-017-0137-z. eCollection 2017.

35.

Characterizing white matter changes in chronic schizophrenia: A free-water imaging multi-site study.

Oestreich LKL, Lyall AE, Pasternak O, Kikinis Z, Newell DT, Savadjiev P, Bouix S, Shenton ME, Kubicki M; Australian Schizophrenia Research Bank, Whitford TJ, McCarthy-Jones S.

Schizophr Res. 2017 Nov;189:153-161. doi: 10.1016/j.schres.2017.02.006. Epub 2017 Feb 10.

36.

Descriptive analysis of unplanned readmission and reoperation rates after intradural spinal tumor resection.

Fisahn C, Sanders FH, Moisi M, Page J, Oakes PC, Wingerson M, Dettori J, Tubbs RS, Chamiraju P, Nora P, Newell D, Delashaw J, Oskouian RJ, Chapman JR.

J Clin Neurosci. 2017 Apr;38:32-36. doi: 10.1016/j.jocn.2016.12.013. Epub 2017 Jan 11.

PMID:
28089196
37.

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines.

Coxon CR, Anscombe E, Harnor SJ, Martin MP, Carbain B, Golding BT, Hardcastle IR, Harlow LK, Korolchuk S, Matheson CJ, Newell DR, Noble ME, Sivaprakasam M, Tudhope SJ, Turner DM, Wang LZ, Wedge SR, Wong C, Griffin RJ, Endicott JA, Cano C.

J Med Chem. 2017 Mar 9;60(5):1746-1767. doi: 10.1021/acs.jmedchem.6b01254. Epub 2017 Feb 14.

38.

Corrigendum to "Increased diffusivity in gray matter in recent onset schizophrenia is associated with clinical symptoms and social cognition" [Schizophr. Res. 176 (2-3) (Oct 2016) 144-150].

Lee JS, Kim CY, Joo YH, Newell D, Bouix S, Shenton ME, Kubicki M.

Schizophr Res. 2017 Mar;181:137. doi: 10.1016/j.schres.2016.11.001. Epub 2016 Nov 25. No abstract available.

PMID:
27890401
39.

Exploring the neural substrates of attentional control and human intelligence: Diffusion tensor imaging of prefrontal white matter tractography in healthy cognition.

Ohtani T, Nestor PG, Bouix S, Newell D, Melonakos ED, McCarley RW, Shenton ME, Kubicki M.

Neuroscience. 2017 Jan 26;341:52-60. doi: 10.1016/j.neuroscience.2016.11.002. Epub 2016 Nov 10.

PMID:
27840231
40.

Enhanced anti-tumour activity of the combination of the novel MEK inhibitor WX-554 and the novel PI3K inhibitor WX-037.

Haagensen EJ, Thomas HD, Schmalix WA, Payne AC, Kevorkian L, Allen RA, Bevan P, Maxwell RJ, Newell DR.

Cancer Chemother Pharmacol. 2016 Dec;78(6):1269-1281. doi: 10.1007/s00280-016-3186-4. Epub 2016 Nov 11.

41.

Structure-guided design of purine-based probes for selective Nek2 inhibition.

Coxon CR, Wong C, Bayliss R, Boxall K, Carr KH, Fry AM, Hardcastle IR, Matheson CJ, Newell DR, Sivaprakasam M, Thomas H, Turner D, Yeoh S, Wang LZ, Griffin RJ, Golding BT, Cano C.

Oncotarget. 2017 Mar 21;8(12):19089-19124. doi: 10.18632/oncotarget.13249.

42.

The impact of patient-reported outcome measures in clinical practice for pain: a systematic review.

Holmes MM, Lewith G, Newell D, Field J, Bishop FL.

Qual Life Res. 2017 Feb;26(2):245-257. doi: 10.1007/s11136-016-1449-5. Epub 2016 Nov 4. Review.

43.

Herpes Simplex Encephalitis of the Parietal Lobe: A Rare Presentation.

Fisahn C, Tkachenko L, Moisi M, Rostad S, Umeh R, Zwillman ME, Tubbs RS, Page J, Newell DW, Delashaw JB.

Cureus. 2016 Sep 16;8(9):e785.

44.

An Interdisciplinary Approach to Reducing Length of Stay in Joint Replacement Patients.

McCann-Spry L, Pelton J, Grandy G, Newell D.

Orthop Nurs. 2016 Sep-Oct;35(5):279-98. doi: 10.1097/NOR.0000000000000274.

PMID:
27648788
45.

Sulfatase-2: a prognostic biomarker and candidate therapeutic target in patients with pancreatic ductal adenocarcinoma.

Alhasan SF, Haugk B, Ogle LF, Beale GS, Long A, Burt AD, Tiniakos D, Televantou D, Coxon F, Newell DR, Charnley R, Reeves HL.

Br J Cancer. 2016 Sep 27;115(7):797-804. doi: 10.1038/bjc.2016.264. Epub 2016 Aug 25.

46.

Increased diffusivity in gray matter in recent onset schizophrenia is associated with clinical symptoms and social cognition.

Lee JS, Kim CY, Joo YH, Newell D, Bouix S, Shenton ME, Kubicki M.

Schizophr Res. 2016 Oct;176(2-3):144-150. doi: 10.1016/j.schres.2016.08.011. Epub 2016 Aug 21. Erratum in: Schizophr Res. 2017 Mar;181:137.

47.

Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer.

Beale G, Haagensen EJ, Thomas HD, Wang LZ, Revill CH, Payne SL, Golding BT, Hardcastle IR, Newell DR, Griffin RJ, Cano C.

Br J Cancer. 2016 Sep 6;115(6):682-90. doi: 10.1038/bjc.2016.238. Epub 2016 Aug 16.

48.

Venous air embolus during prone cervical spine fusion: case report.

Cruz AS, Moisi M, Page J, Tubbs RS, Paulson D, Zwillman M, Oskouian R, Lam A, Newell DW.

J Neurosurg Spine. 2016 Dec;25(6):681-684. Epub 2016 Jul 22.

PMID:
27448172
49.

High-Throughput Screening and Hit Validation of Extracellular-Related Kinase 5 (ERK5) Inhibitors.

Myers SM, Bawn RH, Bisset LC, Blackburn TJ, Cottyn B, Molyneux L, Wong AC, Cano C, Clegg W, Harrington RW, Leung H, Rigoreau L, Vidot S, Golding BT, Griffin RJ, Hammonds T, Newell DR, Hardcastle IR.

ACS Comb Sci. 2016 Aug 8;18(8):444-55. doi: 10.1021/acscombsci.5b00155. Epub 2016 Jul 20.

PMID:
27400250
50.

Invited Article: A precise instrument to determine the Planck constant, and the future kilogram.

Haddad D, Seifert F, Chao LS, Li S, Newell DB, Pratt JR, Williams C, Schlamminger S.

Rev Sci Instrum. 2016 Jun;87(6):061301. doi: 10.1063/1.4953825.

PMID:
27370418

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