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Items: 7


A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes.

Giamarchi A, Feng S, Rodat-Despoix L, Xu Y, Bubenshchikova E, Newby LJ, Hao J, Gaudioso C, Crest M, Lupas AN, Honoré E, Williamson MP, Obara T, Ong AC, Delmas P.

EMBO J. 2010 Apr 7;29(7):1176-91. doi: 10.1038/emboj.2010.18. Epub 2010 Feb 18.


Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2.

Feng S, Okenka GM, Bai CX, Streets AJ, Newby LJ, DeChant BT, Tsiokas L, Obara T, Ong AC.

J Biol Chem. 2008 Oct 17;283(42):28471-9. doi: 10.1074/jbc.M803834200. Epub 2008 Aug 13.


Hyperproliferation of PKD1 cystic cells is induced by insulin-like growth factor-1 activation of the Ras/Raf signalling system.

Parker E, Newby LJ, Sharpe CC, Rossetti S, Streets AJ, Harris PC, O'Hare MJ, Ong AC.

Kidney Int. 2007 Jul;72(2):157-65. Epub 2007 Mar 28.


Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion.

Streets AJ, Newby LJ, O'Hare MJ, Bukanov NO, Ibraghimov-Beskrovnaya O, Ong AC.

J Am Soc Nephrol. 2003 Jul;14(7):1804-15.


Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.

Newby LJ, Streets AJ, Zhao Y, Harris PC, Ward CJ, Ong AC.

J Biol Chem. 2002 Jun 7;277(23):20763-73. Epub 2002 Mar 18.


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