Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 119

1.

Progression of the canonical reference malaria parasite genome from 2002-2019.

Böhme U, Otto TD, Sanders M, Newbold CI, Berriman M.

Version 2. Wellcome Open Res. 2019 May 28 [revised 2019 Jan 1];4:58. doi: 10.12688/wellcomeopenres.15194.2. eCollection 2019.

2.

Pre-clinical evaluation of a P. berghei-based whole-sporozoite malaria vaccine candidate.

Mendes AM, Reuling IJ, Andrade CM, Otto TD, Machado M, Teixeira F, Pissarra J, Gonçalves-Rosa N, Bonaparte D, Sinfrónio J, Sanders M, Janse CJ, Khan SM, Newbold CI, Berriman M, Lee CK, Wu Y, Ockenhouse CF, Sauerwein RW, Prudêncio M.

NPJ Vaccines. 2018 Nov 27;3:54. doi: 10.1038/s41541-018-0091-3. eCollection 2018.

3.

Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres.

Otto TD, Böhme U, Sanders M, Reid A, Bruske EI, Duffy CW, Bull PC, Pearson RD, Abdi A, Dimonte S, Stewart LB, Campino S, Kekre M, Hamilton WL, Claessens A, Volkman SK, Ndiaye D, Amambua-Ngwa A, Diakite M, Fairhurst RM, Conway DJ, Franck M, Newbold CI, Berriman M.

Wellcome Open Res. 2018 May 3;3:52. doi: 10.12688/wellcomeopenres.14571.1. eCollection 2018.

4.

Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals.

Böhme U, Otto TD, Cotton JA, Steinbiss S, Sanders M, Oyola SO, Nicot A, Gandon S, Patra KP, Herd C, Bushell E, Modrzynska KK, Billker O, Vinetz JM, Rivero A, Newbold CI, Berriman M.

Genome Res. 2018 Apr;28(4):547-560. doi: 10.1101/gr.218123.116. Epub 2018 Mar 2.

5.

In silico guided reconstruction and analysis of ICAM-1-binding var genes from Plasmodium falciparum.

Carrington E, Otto TD, Szestak T, Lennartz F, Higgins MK, Newbold CI, Craig AG.

Sci Rep. 2018 Feb 19;8(1):3282. doi: 10.1038/s41598-018-21591-8.

6.

Genomic Characterization of Recrudescent Plasmodium malariae after Treatment with Artemether/Lumefantrine.

Rutledge GG, Marr I, Huang GKL, Auburn S, Marfurt J, Sanders M, White NJ, Berriman M, Newbold CI, Anstey NM, Otto TD, Price RN.

Emerg Infect Dis. 2017 Aug;23(8):1300-1307. doi: 10.3201/eid2308.161582. Epub 2017 Aug 15.

7.

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution.

Rutledge GG, Böhme U, Sanders M, Reid AJ, Cotton JA, Maiga-Ascofare O, Djimdé AA, Apinjoh TO, Amenga-Etego L, Manske M, Barnwell JW, Renaud F, Ollomo B, Prugnolle F, Anstey NM, Auburn S, Price RN, McCarthy JS, Kwiatkowski DP, Newbold CI, Berriman M, Otto TD.

Nature. 2017 Feb 2;542(7639):101-104. doi: 10.1038/nature21038. Epub 2017 Jan 25.

8.

A new Plasmodium vivax reference sequence with improved assembly of the subtelomeres reveals an abundance of pir genes.

Auburn S, Böhme U, Steinbiss S, Trimarsanto H, Hostetler J, Sanders M, Gao Q, Nosten F, Newbold CI, Berriman M, Price RN, Otto TD.

Wellcome Open Res. 2016 Nov 15;1:4. doi: 10.12688/wellcomeopenres.9876.1.

9.

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification.

Oyola SO, Ariani CV, Hamilton WL, Kekre M, Amenga-Etego LN, Ghansah A, Rutledge GG, Redmond S, Manske M, Jyothi D, Jacob CG, Otto TD, Rockett K, Newbold CI, Berriman M, Kwiatkowski DP.

Malar J. 2016 Dec 20;15(1):597. doi: 10.1186/s12936-016-1641-7.

10.

A comprehensive evaluation of rodent malaria parasite genomes and gene expression.

Otto TD, Böhme U, Jackson AP, Hunt M, Franke-Fayard B, Hoeijmakers WA, Religa AA, Robertson L, Sanders M, Ogun SA, Cunningham D, Erhart A, Billker O, Khan SM, Stunnenberg HG, Langhorne J, Holder AA, Waters AP, Newbold CI, Pain A, Berriman M, Janse CJ.

BMC Biol. 2014 Oct 30;12:86. doi: 10.1186/s12915-014-0086-0.

11.

The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria.

Noble R, Christodoulou Z, Kyes S, Pinches R, Newbold CI, Recker M.

Elife. 2013 Sep 17;2:e01074. doi: 10.7554/eLife.01074.

12.

Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation.

Lemieux JE, Kyes SA, Otto TD, Feller AI, Eastman RT, Pinches RA, Berriman M, Su XZ, Newbold CI.

Mol Microbiol. 2013 Nov;90(3):519-37. doi: 10.1111/mmi.12381. Epub 2013 Sep 30.

13.

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia.

Miotto O, Almagro-Garcia J, Manske M, Macinnis B, Campino S, Rockett KA, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Duong S, Nguon C, Chuor CM, Saunders D, Se Y, Lon C, Fukuda MM, Amenga-Etego L, Hodgson AV, Asoala V, Imwong M, Takala-Harrison S, Nosten F, Su XZ, Ringwald P, Ariey F, Dolecek C, Hien TT, Boni MF, Thai CQ, Amambua-Ngwa A, Conway DJ, Djimdé AA, Doumbo OK, Zongo I, Ouedraogo JB, Alcock D, Drury E, Auburn S, Koch O, Sanders M, Hubbart C, Maslen G, Ruano-Rubio V, Jyothi D, Miles A, O'Brien J, Gamble C, Oyola SO, Rayner JC, Newbold CI, Berriman M, Spencer CC, McVean G, Day NP, White NJ, Bethell D, Dondorp AM, Plowe CV, Fairhurst RM, Kwiatkowski DP.

Nat Genet. 2013 Jun;45(6):648-55. doi: 10.1038/ng.2624. Epub 2013 Apr 28.

14.

Efficient depletion of host DNA contamination in malaria clinical sequencing.

Oyola SO, Gu Y, Manske M, Otto TD, O'Brien J, Alcock D, Macinnis B, Berriman M, Newbold CI, Kwiatkowski DP, Swerdlow HP, Quail MA.

J Clin Microbiol. 2013 Mar;51(3):745-51. doi: 10.1128/JCM.02507-12. Epub 2012 Dec 5.

15.

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.

Amambua-Ngwa A, Tetteh KK, Manske M, Gomez-Escobar N, Stewart LB, Deerhake ME, Cheeseman IH, Newbold CI, Holder AA, Knuepfer E, Janha O, Jallow M, Campino S, Macinnis B, Kwiatkowski DP, Conway DJ.

PLoS Genet. 2012;8(11):e1002992. doi: 10.1371/journal.pgen.1002992. Epub 2012 Nov 1.

16.

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing.

Manske M, Miotto O, Campino S, Auburn S, Almagro-Garcia J, Maslen G, O'Brien J, Djimde A, Doumbo O, Zongo I, Ouedraogo JB, Michon P, Mueller I, Siba P, Nzila A, Borrmann S, Kiara SM, Marsh K, Jiang H, Su XZ, Amaratunga C, Fairhurst R, Socheat D, Nosten F, Imwong M, White NJ, Sanders M, Anastasi E, Alcock D, Drury E, Oyola S, Quail MA, Turner DJ, Ruano-Rubio V, Jyothi D, Amenga-Etego L, Hubbart C, Jeffreys A, Rowlands K, Sutherland C, Roper C, Mangano V, Modiano D, Tan JC, Ferdig MT, Amambua-Ngwa A, Conway DJ, Takala-Harrison S, Plowe CV, Rayner JC, Rockett KA, Clark TG, Newbold CI, Berriman M, MacInnis B, Kwiatkowski DP.

Nature. 2012 Jul 19;487(7407):375-9. doi: 10.1038/nature11174.

17.

An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing.

Auburn S, Campino S, Clark TG, Djimde AA, Zongo I, Pinches R, Manske M, Mangano V, Alcock D, Anastasi E, Maslen G, Macinnis B, Rockett K, Modiano D, Newbold CI, Doumbo OK, Ouédraogo JB, Kwiatkowski DP.

PLoS One. 2011;6(7):e22213. doi: 10.1371/journal.pone.0022213. Epub 2011 Jul 18.

18.

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay.

Campino S, Auburn S, Kivinen K, Zongo I, Ouedraogo JB, Mangano V, Djimde A, Doumbo OK, Kiara SM, Nzila A, Borrmann S, Marsh K, Michon P, Mueller I, Siba P, Jiang H, Su XZ, Amaratunga C, Socheat D, Fairhurst RM, Imwong M, Anderson T, Nosten F, White NJ, Gwilliam R, Deloukas P, MacInnis B, Newbold CI, Rockett K, Clark TG, Kwiatkowski DP.

PLoS One. 2011;6(6):e20251. doi: 10.1371/journal.pone.0020251. Epub 2011 Jun 6.

19.

Host-mediated regulation of superinfection in malaria.

Portugal S, Carret C, Recker M, Armitage AE, Gonçalves LA, Epiphanio S, Sullivan D, Roy C, Newbold CI, Drakesmith H, Mota MM.

Nat Med. 2011 Jun;17(6):732-7. doi: 10.1038/nm.2368. Epub 2011 May 15.

20.

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern.

Recker M, Buckee CO, Serazin A, Kyes S, Pinches R, Christodoulou Z, Springer AL, Gupta S, Newbold CI.

PLoS Pathog. 2011 Mar;7(3):e1001306. doi: 10.1371/journal.ppat.1001306. Epub 2011 Mar 3.

21.

Plasmodium falciparum infected erythrocytes induce hepcidin (HAMP) mRNA synthesis by peripheral blood mononuclear cells.

Armitage AE, Pinches R, Eddowes LA, Newbold CI, Drakesmith H.

Br J Haematol. 2009 Dec;147(5):769-71. doi: 10.1111/j.1365-2141.2009.07880.x. Epub 2009 Aug 31. No abstract available.

PMID:
19747361
22.

SnoopCGH: software for visualizing comparative genomic hybridization data.

Almagro-Garcia J, Manske M, Carret C, Campino S, Auburn S, Macinnis BL, Maslen G, Pain A, Newbold CI, Kwiatkowski DP, Clark TG.

Bioinformatics. 2009 Oct 15;25(20):2732-3. doi: 10.1093/bioinformatics/btp488. Epub 2009 Aug 16.

23.

Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture.

Lemieux JE, Gomez-Escobar N, Feller A, Carret C, Amambua-Ngwa A, Pinches R, Day F, Kyes SA, Conway DJ, Holmes CC, Newbold CI.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7559-64. doi: 10.1073/pnas.0811829106. Epub 2009 Apr 17.

24.

The genome of the simian and human malaria parasite Plasmodium knowlesi.

Pain A, Böhme U, Berry AE, Mungall K, Finn RD, Jackson AP, Mourier T, Mistry J, Pasini EM, Aslett MA, Balasubrammaniam S, Borgwardt K, Brooks K, Carret C, Carver TJ, Cherevach I, Chillingworth T, Clark TG, Galinski MR, Hall N, Harper D, Harris D, Hauser H, Ivens A, Janssen CS, Keane T, Larke N, Lapp S, Marti M, Moule S, Meyer IM, Ormond D, Peters N, Sanders M, Sanders S, Sargeant TJ, Simmonds M, Smith F, Squares R, Thurston S, Tivey AR, Walker D, White B, Zuiderwijk E, Churcher C, Quail MA, Cowman AF, Turner CM, Rajandream MA, Kocken CH, Thomas AW, Newbold CI, Barrell BG, Berriman M.

Nature. 2008 Oct 9;455(7214):799-803. doi: 10.1038/nature07306.

25.

Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1.

Mackintosh CL, Christodoulou Z, Mwangi TW, Kortok M, Pinches R, Williams TN, Marsh K, Newbold CI.

Malar J. 2008 Aug 16;7:155. doi: 10.1186/1475-2875-7-155.

26.

Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children.

Mackintosh CL, Mwangi T, Kinyanjui SM, Mosobo M, Pinches R, Williams TN, Newbold CI, Marsh K.

Int J Parasitol. 2008 Oct;38(12):1445-54. doi: 10.1016/j.ijpara.2008.03.009. Epub 2008 Apr 29.

27.

Plasmodium falciparum antigenic variation. Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks.

Bull PC, Buckee CO, Kyes S, Kortok MM, Thathy V, Guyah B, Stoute JA, Newbold CI, Marsh K.

Mol Microbiol. 2008 Jun;68(6):1519-34. doi: 10.1111/j.1365-2958.2008.06248.x. Epub 2008 Apr 21.

28.

An approach to classifying sequence tags sampled from Plasmodium falciparum var genes.

Bull PC, Kyes S, Buckee CO, Montgomery J, Kortok MM, Newbold CI, Marsh K.

Mol Biochem Parasitol. 2007 Jul;154(1):98-102. Epub 2007 Mar 25. No abstract available.

29.

Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.

Kraemer SM, Kyes SA, Aggarwal G, Springer AL, Nelson SO, Christodoulou Z, Smith LM, Wang W, Levin E, Newbold CI, Myler PJ, Smith JD.

BMC Genomics. 2007 Feb 7;8:45.

30.

Plasmodium cysteine repeat modular proteins 1-4: complex proteins with roles throughout the malaria parasite life cycle.

Thompson J, Fernandez-Reyes D, Sharling L, Moore SG, Eling WM, Kyes SA, Newbold CI, Kafatos FC, Janse CJ, Waters AP.

Cell Microbiol. 2007 Jun;9(6):1466-80. Epub 2007 Jan 23.

PMID:
17253978
31.

Reply.

Rowe JA, Newbold CI, Moulds JM, Miller LH.

Parasitol Today. 1998 Dec;14(6):250. No abstract available.

PMID:
17040770
32.

The frequency of BDCA3-positive dendritic cells is increased in the peripheral circulation of Kenyan children with severe malaria.

Urban BC, Cordery D, Shafi MJ, Bull PC, Newbold CI, Williams TN, Marsh K.

Infect Immun. 2006 Dec;74(12):6700-6. Epub 2006 Sep 25.

33.

Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains.

Frankland S, Adisa A, Horrocks P, Taraschi TF, Schneider T, Elliott SR, Rogerson SJ, Knuepfer E, Cowman AF, Newbold CI, Tilley L.

Eukaryot Cell. 2006 May;5(5):849-60.

34.
35.

Plasmodium falciparum variant surface antigen expression patterns during malaria.

Bull PC, Berriman M, Kyes S, Quail MA, Hall N, Kortok MM, Marsh K, Newbold CI.

PLoS Pathog. 2005 Nov;1(3):e26. Epub 2005 Nov 18.

36.

Plasmodium falciparum antigenic variation: relationships between in vivo selection, acquired antibody response, and disease severity.

Bull PC, Pain A, Ndungu FM, Kinyanjui SM, Roberts DJ, Newbold CI, Marsh K.

J Infect Dis. 2005 Sep 15;192(6):1119-26. Epub 2005 Aug 12. Erratum in: J Infect Dis. 2005 Nov 1;192(9):1678.

PMID:
16107968
37.

PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytes.

Horrocks P, Pinches RA, Chakravorty SJ, Papakrivos J, Christodoulou Z, Kyes SA, Urban BC, Ferguson DJ, Newbold CI.

J Cell Sci. 2005 Jun 1;118(Pt 11):2507-18.

39.

Antibodies to voltage-gated calcium channels in children with falciparum malaria.

Lang B, Newbold CI, Williams G, Peshu N, Marsh K, Newton CR.

J Infect Dis. 2005 Jan 1;191(1):117-21. Epub 2004 Dec 1.

PMID:
15593012
40.
41.

Variable var transition rates underlie antigenic variation in malaria.

Horrocks P, Pinches R, Christodoulou Z, Kyes SA, Newbold CI.

Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11129-34. Epub 2004 Jul 15.

42.

The use of cryopreserved mature trophozoites in assessing antibody recognition of variant surface antigens of Plasmodium falciparum-infected erythrocytes.

Kinyanjui SM, Howard T, Williams TN, Bull PC, Newbold CI, Marsh K.

J Immunol Methods. 2004 May;288(1-2):9-18.

PMID:
15183081
43.

Characterization of the pathway for transport of the cytoadherence-mediating protein, PfEMP1, to the host cell surface in malaria parasite-infected erythrocytes.

Kriek N, Tilley L, Horrocks P, Pinches R, Elford BC, Ferguson DJ, Lingelbach K, Newbold CI.

Mol Microbiol. 2003 Nov;50(4):1215-27.

45.

A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern.

Kyes SA, Christodoulou Z, Raza A, Horrocks P, Pinches R, Rowe JA, Newbold CI.

Mol Microbiol. 2003 Jun;48(5):1339-48.

46.

Kinetics of antibody responses to Plasmodium falciparum-infected erythrocyte variant surface antigens.

Kinyanjui SM, Bull P, Newbold CI, Marsh K.

J Infect Dis. 2003 Feb 15;187(4):667-74. Epub 2003 Feb 7.

PMID:
12599084
47.

Effect of var gene disruption on switching in Plasmodium falciparum.

Horrocks P, Pinches R, Kyes S, Kriek N, Lee S, Christodoulou Z, Newbold CI.

Mol Microbiol. 2002 Aug;45(4):1131-41.

48.
49.

Mapping of the region of complement receptor (CR) 1 required for Plasmodium falciparum rosetting and demonstration of the importance of CR1 in rosetting in field isolates.

Rowe JA, Rogerson SJ, Raza A, Moulds JM, Kazatchkine MD, Marsh K, Newbold CI, Atkinson JP, Miller LH.

J Immunol. 2000 Dec 1;165(11):6341-6.

50.

Var gene diversity in Plasmodium falciparum is generated by frequent recombination events.

Taylor HM, Kyes SA, Newbold CI.

Mol Biochem Parasitol. 2000 Oct;110(2):391-7. No abstract available.

PMID:
11071291

Supplemental Content

Loading ...
Support Center