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Items: 27

1.

Detection and Quantitation of Selected Food Allergens by Liquid Chromatography with Tandem Mass Spectrometry: First Action 2017.17.

New LS, Stahl-Zeng J, Schreiber A, Cafazzo M, Liu A, Brunelle S, Liu HF.

J AOAC Int. 2019 Oct 23. doi: 10.5740/jaoacint.19-0112. [Epub ahead of print]

PMID:
31645235
2.

Simultaneous Analysis of Multiple Allergens in Food Products by LC-MS/MS.

New LS, Schreiber A, Stahl-Zeng J, Liu HF.

J AOAC Int. 2018 Jan 1;101(1):132-145. doi: 10.5740/jaoacint.17-0403. Epub 2017 Dec 5.

PMID:
29202922
3.

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Bard-Chapeau EA, Nguyen AT, Rust AG, Sayadi A, Lee P, Chua BQ, New LS, de Jong J, Ward JM, Chin CK, Chew V, Toh HC, Abastado JP, Benoukraf T, Soong R, Bard FA, Dupuy AJ, Johnson RL, Radda GK, Chan EC, Wessels LF, Adams DJ, Jenkins NA, Copeland NG.

Nat Genet. 2014 Jan;46(1):24-32. doi: 10.1038/ng.2847. Epub 2013 Dec 8.

4.

Optimizing hollow-fiber-based pharmacokinetic assay via chemical stability study to account for inaccurate simulated drug clearance of rifampicin.

New LS, Lim TP, Oh JW, Cheah GJ, Kwa AL, Chan EC.

Anal Bioanal Chem. 2013 Feb;405(4):1407-15. doi: 10.1007/s00216-012-6549-7. Epub 2012 Nov 24.

PMID:
23180085
5.

Pyrrolidinediones reduce the toxicity of thiazolidinediones and modify their anti-diabetic and anti-cancer properties.

Saha S, Chan DS, Lee CY, Wong W, New LS, Chui WK, Yap CW, Chan EC, Ho HK.

Eur J Pharmacol. 2012 Dec 15;697(1-3):13-23. doi: 10.1016/j.ejphar.2012.09.021. Epub 2012 Oct 4.

PMID:
23041271
6.

Interaction of lapatinib with cytochrome P450 3A5.

Chan EC, New LS, Chua TB, Yap CW, Ho HK, Nelson SD.

Drug Metab Dispos. 2012 Jul;40(7):1414-22. doi: 10.1124/dmd.112.044958. Epub 2012 Apr 17.

PMID:
22511346
7.

Preclinical metabolism and disposition of SB939 (Pracinostat), an orally active histone deacetylase inhibitor, and prediction of human pharmacokinetics.

Jayaraman R, Pilla Reddy V, Pasha MK, Wang H, Sangthongpitag K, Yeo P, Hu CY, Wu X, Xin L, Goh E, New LS, Ethirajulu K.

Drug Metab Dispos. 2011 Dec;39(12):2219-32. doi: 10.1124/dmd.111.041558. Epub 2011 Aug 26.

PMID:
21873472
8.

Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation.

Chan CY, New LS, Ho HK, Chan EC.

Toxicol Lett. 2011 Oct 30;206(3):314-24. doi: 10.1016/j.toxlet.2011.07.019. Epub 2011 Aug 5.

PMID:
21839818
9.

Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.

Takakusa H, Wahlin MD, Zhao C, Hanson KL, New LS, Chan EC, Nelson SD.

Drug Metab Dispos. 2011 Jun;39(6):1022-30. doi: 10.1124/dmd.110.037531. Epub 2011 Mar 1.

10.

Metabolic profiling of 3-nitropropionic acid early-stage Huntington's disease rat model using gas chromatography time-of-flight mass spectrometry.

Chang KL, New LS, Mal M, Goh CW, Aw CC, Browne ER, Chan EC.

J Proteome Res. 2011 Apr 1;10(4):2079-87. doi: 10.1021/pr2000336. Epub 2011 Mar 16.

PMID:
21355552
11.

Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib.

Teng WC, Oh JW, New LS, Wahlin MD, Nelson SD, Ho HK, Chan EC.

Mol Pharmacol. 2010 Oct;78(4):693-703. doi: 10.1124/mol.110.065839. Epub 2010 Jul 12.

PMID:
20624855
12.

Direct toxicity effects of sulfo-conjugated troglitazone on human hepatocytes.

Saha S, New LS, Ho HK, Chui WK, Chan EC.

Toxicol Lett. 2010 Jun 2;195(2-3):135-41. doi: 10.1016/j.toxlet.2010.03.010. Epub 2010 Mar 20.

PMID:
20307632
13.

Ultra-high performance liquid chromatography/time-of-flight mass spectrometry (UHPLC/TOFMS) for time-dependent profiling of raw and steamed Panax notoginseng.

Toh DF, New LS, Koh HL, Chan EC.

J Pharm Biomed Anal. 2010 May 1;52(1):43-50. doi: 10.1016/j.jpba.2009.12.005. Epub 2009 Dec 22.

PMID:
20079593
14.

Investigation of the role of the thiazolidinedione ring of troglitazone in inducing hepatotoxicity.

Saha S, New LS, Ho HK, Chui WK, Chan EC.

Toxicol Lett. 2010 Feb 1;192(2):141-9. doi: 10.1016/j.toxlet.2009.10.014. Epub 2009 Oct 23.

PMID:
19854250
15.

Metabolic profiling of rat brain and cognitive behavioral tasks: potential complementary strategies in preclinical cognition enhancement research.

Goh DP, Neo AH, Goh CW, Aw CC, New LS, Chen WS, Atcha Z, Browne ER, Chan EC.

J Proteome Res. 2009 Dec;8(12):5679-90. doi: 10.1021/pr900795g.

PMID:
19845403
16.

A sensitive LC/MS/MS bioanalysis assay of orally administered lipoic acid in rat blood and brain tissue.

Chng HT, New LS, Neo AH, Goh CW, Browne ER, Chan EC.

J Pharm Biomed Anal. 2010 Feb 5;51(3):754-7. doi: 10.1016/j.jpba.2009.09.028. Epub 2009 Sep 27.

PMID:
19833467
17.

Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity.

Kashimshetty R, Desai VG, Kale VM, Lee T, Moland CL, Branham WS, New LS, Chan EC, Younis H, Boelsterli UA.

Toxicol Appl Pharmacol. 2009 Jul 15;238(2):150-9. doi: 10.1016/j.taap.2009.05.007. Epub 2009 May 12.

PMID:
19442681
19.

Pharmaceutical metabolite profiling using quadrupole/ion mobility spectrometry/time-of-flight mass spectrometry.

Chan EC, New LS, Yap CW, Goh LT.

Rapid Commun Mass Spectrom. 2009 Feb;23(3):384-94. doi: 10.1002/rcm.3887.

PMID:
19127546
20.

Distribution study of orally administered lipoic acid in rat brain tissues.

Chng HT, New LS, Neo AH, Goh CW, Browne ER, Chan EC.

Brain Res. 2009 Jan 28;1251:80-6. doi: 10.1016/j.brainres.2008.11.025. Epub 2008 Nov 19.

PMID:
19046949
21.

Investigation of the drug-drug interaction between alpha-lipoic acid and valproate via mitochondrial beta-oxidation.

Phua LC, New LS, Goh CW, Neo AH, Browne ER, Chan EC.

Pharm Res. 2008 Nov;25(11):2639-49. doi: 10.1007/s11095-008-9681-5. Epub 2008 Jul 18.

PMID:
18636319
22.

Prevention of acetaminophen (APAP)-induced hepatotoxicity by leflunomide via inhibition of APAP biotransformation to N-acetyl-p-benzoquinone imine.

Tan SC, New LS, Chan EC.

Toxicol Lett. 2008 Aug 28;180(3):174-81. doi: 10.1016/j.toxlet.2008.06.001. Epub 2008 Jun 8.

PMID:
18588957
24.

In vitro metabolism of leflunomide by mouse and human liver microsomes.

Chan EC, New LS.

Drug Metab Lett. 2007 Dec;1(4):299-305.

PMID:
19356059
25.

In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species.

Venkatesh PR, Goh E, Zeng P, New LS, Xin L, Pasha MK, Sangthongpitag K, Yeo P, Kantharaj E.

Biol Pharm Bull. 2007 May;30(5):1021-4.

26.

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