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Items: 43

1.

Glycerol as a substrate for Saccharomyces cerevisiae based bioprocesses - Knowledge gaps regarding the central carbon catabolism of this 'non-fermentable' carbon source.

Xiberras J, Klein M, Nevoigt E.

Biotechnol Adv. 2019 Nov 1;37(6):107378. doi: 10.1016/j.biotechadv.2019.03.017. Epub 2019 Mar 28. Review.

2.

Involvement of the external mitochondrial NADH dehydrogenase Nde1 in glycerol metabolism by wild-type and engineered Saccharomyces cerevisiae strains.

Aßkamp MR, Klein M, Nevoigt E.

FEMS Yeast Res. 2019 May 1;19(3). pii: foz026. doi: 10.1093/femsyr/foz026.

PMID:
30915433
3.

Forcing fermentation: Profiling proteins, peptides and polyphenols in lab-scale cocoa bean fermentation.

John WA, Böttcher NL, Aßkamp M, Bergounhou A, Kumari N, Ho PW, D'Souza RN, Nevoigt E, Ullrich MS.

Food Chem. 2019 Apr 25;278:786-794. doi: 10.1016/j.foodchem.2018.11.108. Epub 2018 Dec 2.

PMID:
30583444
4.

Identification of novel genes involved in acetic acid tolerance of Saccharomyces cerevisiae using pooled-segregant RNA sequencing.

Fernández-Niño M, Pulido S, Stefanoska D, Pérez C, González-Ramos D, van Maris AJA, Marchal K, Nevoigt E, Swinnen S.

FEMS Yeast Res. 2018 Dec 1;18(8). doi: 10.1093/femsyr/foy100.

PMID:
30219856
5.

Glycerol positive promoters for tailored metabolic engineering of the yeast Saccharomyces cerevisiae.

Ho PW, Klein M, Futschik M, Nevoigt E.

FEMS Yeast Res. 2018 May 1;18(3). doi: 10.1093/femsyr/foy019.

PMID:
29481685
6.

A modular metabolic engineering approach for the production of 1,2-propanediol from glycerol by Saccharomyces cerevisiae.

Islam ZU, Klein M, Aßkamp MR, Ødum ASR, Nevoigt E.

Metab Eng. 2017 Nov;44:223-235. doi: 10.1016/j.ymben.2017.10.002. Epub 2017 Oct 9.

PMID:
29024819
7.

Improvement of yeast tolerance to acetic acid through Haa1 transcription factor engineering: towards the underlying mechanisms.

Swinnen S, Henriques SF, Shrestha R, Ho PW, Sá-Correia I, Nevoigt E.

Microb Cell Fact. 2017 Jan 9;16(1):7. doi: 10.1186/s12934-016-0621-5.

8.

The sole introduction of two single-point mutations establishes glycerol utilization in Saccharomyces cerevisiae CEN.PK derivatives.

Ho PW, Swinnen S, Duitama J, Nevoigt E.

Biotechnol Biofuels. 2017 Jan 3;10:10. doi: 10.1186/s13068-016-0696-6. eCollection 2017.

9.

Glycerol metabolism and transport in yeast and fungi: established knowledge and ambiguities.

Klein M, Swinnen S, Thevelein JM, Nevoigt E.

Environ Microbiol. 2017 Mar;19(3):878-893. doi: 10.1111/1462-2920.13617. Epub 2017 Jan 30. Review.

PMID:
27878932
10.

Towards the exploitation of glycerol's high reducing power in Saccharomyces cerevisiae-based bioprocesses.

Klein M, Carrillo M, Xiberras J, Islam ZU, Swinnen S, Nevoigt E.

Metab Eng. 2016 Nov;38:464-472. doi: 10.1016/j.ymben.2016.10.008. Epub 2016 Oct 14.

PMID:
27750033
11.

The expression of glycerol facilitators from various yeast species improves growth on glycerol of Saccharomyces cerevisiae.

Klein M, Islam ZU, Knudsen PB, Carrillo M, Swinnen S, Workman M, Nevoigt E.

Metab Eng Commun. 2016 Sep 29;3:252-257. doi: 10.1016/j.meteno.2016.09.001. eCollection 2016 Dec.

12.

A new laboratory evolution approach to select for constitutive acetic acid tolerance in Saccharomyces cerevisiae and identification of causal mutations.

González-Ramos D, Gorter de Vries AR, Grijseels SS, van Berkum MC, Swinnen S, van den Broek M, Nevoigt E, Daran JM, Pronk JT, van Maris AJ.

Biotechnol Biofuels. 2016 Aug 12;9:173. doi: 10.1186/s13068-016-0583-1. eCollection 2016.

13.

Genetic determinants for enhanced glycerol growth of Saccharomyces cerevisiae.

Swinnen S, Ho PW, Klein M, Nevoigt E.

Metab Eng. 2016 Jul;36:68-79. doi: 10.1016/j.ymben.2016.03.003. Epub 2016 Mar 10.

PMID:
26971668
14.

The art of design.

Meyer V, Nevoigt E, Wiemann P.

Fungal Genet Biol. 2016 Apr;89:1-2. doi: 10.1016/j.fgb.2016.02.006. No abstract available.

PMID:
26968149
15.

The Cytosolic pH of Individual Saccharomyces cerevisiae Cells Is a Key Factor in Acetic Acid Tolerance.

Fernández-Niño M, Marquina M, Swinnen S, Rodríguez-Porrata B, Nevoigt E, Ariño J.

Appl Environ Microbiol. 2015 Nov;81(22):7813-21. doi: 10.1128/AEM.02313-15. Epub 2015 Sep 4.

16.

Natural and modified promoters for tailored metabolic engineering of the yeast Saccharomyces cerevisiae.

Hubmann G, Thevelein JM, Nevoigt E.

Methods Mol Biol. 2014;1152:17-42. doi: 10.1007/978-1-4939-0563-8_2. Review.

PMID:
24744025
17.

The fraction of cells that resume growth after acetic acid addition is a strain-dependent parameter of acetic acid tolerance in Saccharomyces cerevisiae.

Swinnen S, Fernández-Niño M, González-Ramos D, van Maris AJ, Nevoigt E.

FEMS Yeast Res. 2014 Jun;14(4):642-53. doi: 10.1111/1567-1364.12151. Epub 2014 Apr 11.

18.

Re-evaluation of glycerol utilization in Saccharomyces cerevisiae: characterization of an isolate that grows on glycerol without supporting supplements.

Swinnen S, Klein M, Carrillo M, McInnes J, Nguyen HTT, Nevoigt E.

Biotechnol Biofuels. 2013 Nov 8;6(1):157. doi: 10.1186/1754-6834-6-157.

19.

Defects in mitochondrial distribution during the prolonged lag phase of Saccharomyces cerevisiae preceding growth in glycerol as the sole source of carbon.

McInnes J, Rehders M, McFaline-Figueroa JR, Brix K, Pon LA, Nevoigt E.

FEMS Yeast Res. 2013 Nov;13(7):706-10. doi: 10.1111/1567-1364.12085. Epub 2013 Sep 24.

20.

Identification of multiple interacting alleles conferring low glycerol and high ethanol yield in Saccharomyces cerevisiae ethanolic fermentation.

Hubmann G, Mathé L, Foulquié-Moreno MR, Duitama J, Nevoigt E, Thevelein JM.

Biotechnol Biofuels. 2013 Jun 11;6(1):87. doi: 10.1186/1754-6834-6-87.

21.

The metabolic costs of improving ethanol yield by reducing glycerol formation capacity under anaerobic conditions in Saccharomyces cerevisiae.

Pagliardini J, Hubmann G, Alfenore S, Nevoigt E, Bideaux C, Guillouet SE.

Microb Cell Fact. 2013 Mar 28;12:29. doi: 10.1186/1475-2859-12-29.

22.

Quantitative trait analysis of yeast biodiversity yields novel gene tools for metabolic engineering.

Hubmann G, Foulquié-Moreno MR, Nevoigt E, Duitama J, Meurens N, Pais TM, Mathé L, Saerens S, Nguyen HT, Swinnen S, Verstrepen KJ, Concilio L, de Troostembergh JC, Thevelein JM.

Metab Eng. 2013 May;17:68-81. doi: 10.1016/j.ymben.2013.02.006. Epub 2013 Mar 18.

23.

Genetic mapping of quantitative phenotypic traits in Saccharomyces cerevisiae.

Swinnen S, Thevelein JM, Nevoigt E.

FEMS Yeast Res. 2012 Mar;12(2):215-27. doi: 10.1111/j.1567-1364.2011.00777.x. Epub 2012 Jan 24. Review.

24.

Identification of Sc-type ILV6 as a target to reduce diacetyl formation in lager brewers' yeast.

Duong CT, Strack L, Futschik M, Katou Y, Nakao Y, Fujimura T, Shirahige K, Kodama Y, Nevoigt E.

Metab Eng. 2011 Nov;13(6):638-47. doi: 10.1016/j.ymben.2011.07.005. Epub 2011 Aug 3.

PMID:
21824525
25.

Gpd1 and Gpd2 fine-tuning for sustainable reduction of glycerol formation in Saccharomyces cerevisiae.

Hubmann G, Guillouet S, Nevoigt E.

Appl Environ Microbiol. 2011 Sep;77(17):5857-67. doi: 10.1128/AEM.05338-11. Epub 2011 Jul 1.

26.

Directed evolution of promoters and tandem gene arrays for customizing RNA synthesis rates and regulation.

Tyo KE, Nevoigt E, Stephanopoulos G.

Methods Enzymol. 2011;497:135-55. doi: 10.1016/B978-0-12-385075-1.00006-8.

PMID:
21601085
27.

Quantitative evaluation of yeast's requirement for glycerol formation in very high ethanol performance fed-batch process.

Pagliardini J, Hubmann G, Bideaux C, Alfenore S, Nevoigt E, Guillouet SE.

Microb Cell Fact. 2010 May 21;9:36. doi: 10.1186/1475-2859-9-36.

28.

Genetic improvement of brewer's yeast: current state, perspectives and limits.

Saerens SM, Duong CT, Nevoigt E.

Appl Microbiol Biotechnol. 2010 May;86(5):1195-212. doi: 10.1007/s00253-010-2486-6. Epub 2010 Mar 2. Review.

PMID:
20195857
29.

Applications of synthetic biology in microbial biotechnology.

Alper H, Cirino P, Nevoigt E, Sriram G.

J Biomed Biotechnol. 2010;2010:918391. doi: 10.1155/2010/918391. Epub 2011 Mar 2. No abstract available.

30.

Engineering of Saccharomyces cerevisiae for the production of dihydroxyacetone (DHA) from sugars: a proof of concept.

Nguyen HT, Nevoigt E.

Metab Eng. 2009 Nov;11(6):335-46. doi: 10.1016/j.ymben.2009.07.005. Epub 2009 Jul 24.

PMID:
19632352
31.

Progress in metabolic engineering of Saccharomyces cerevisiae.

Nevoigt E.

Microbiol Mol Biol Rev. 2008 Sep;72(3):379-412. doi: 10.1128/MMBR.00025-07. Review.

32.

Improvement of Saccharomyces yeast strains used in brewing, wine making and baking.

Donalies UE, Nguyen HT, Stahl U, Nevoigt E.

Adv Biochem Eng Biotechnol. 2008;111:67-98. doi: 10.1007/10_2008_099. Review.

PMID:
18463806
33.

Fermentative production of L-glycerol 3-phosphate utilizing a Saccharomyces cerevisiae strain with an engineered glycerol biosynthetic pathway.

Popp A, Nguyen HT, Boulahya K, Bideaux C, Alfenore S, Guillouet SE, Nevoigt E.

Biotechnol Bioeng. 2008 Jun 15;100(3):497-505. doi: 10.1002/bit.21777.

PMID:
18438874
34.

Engineering yeast transcription machinery for improved ethanol tolerance and production.

Alper H, Moxley J, Nevoigt E, Fink GR, Stephanopoulos G.

Science. 2006 Dec 8;314(5805):1565-8.

35.

Engineering promoter regulation.

Nevoigt E, Fischer C, Mucha O, Matthäus F, Stahl U, Stephanopoulos G.

Biotechnol Bioeng. 2007 Feb 15;96(3):550-8.

PMID:
16964624
36.

Engineering of promoter replacement cassettes for fine-tuning of gene expression in Saccharomyces cerevisiae.

Nevoigt E, Kohnke J, Fischer CR, Alper H, Stahl U, Stephanopoulos G.

Appl Environ Microbiol. 2006 Aug;72(8):5266-73.

37.

Response to Hammer et al.: Tuning genetic control--importance of thorough promoter characterization versus generating promoter diversity.

Fischer CR, Alper H, Nevoigt E, Jensen KL, Stephanopoulos G.

Trends Biotechnol. 2006 Feb;24(2):55-6. Epub 2005 Dec 27. No abstract available.

PMID:
16380177
38.

Tuning genetic control through promoter engineering.

Alper H, Fischer C, Nevoigt E, Stephanopoulos G.

Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12678-83. Epub 2005 Aug 25. Erratum in: Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):3006.

39.

Engineering of Saccharomyces cerevisiae for the production of L-glycerol 3-phosphate.

Nguyen HT, Dieterich A, Athenstaedt K, Truong NH, Stahl U, Nevoigt E.

Metab Eng. 2004 Apr;6(2):155-63.

PMID:
15113568
40.

Genetic engineering of brewing yeast to reduce the content of ethanol in beer.

Nevoigt E, Pilger R, Mast-Gerlach E, Schmidt U, Freihammer S, Eschenbrenner M, Garbe L, Stahl U.

FEMS Yeast Res. 2002 May;2(2):225-32.

41.
42.

Osmoregulation and glycerol metabolism in the yeast Saccharomyces cerevisiae.

Nevoigt E, Stahl U.

FEMS Microbiol Rev. 1997 Nov;21(3):231-41. Review.

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