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Associations between molecular biomarkers and MR-based cartilage composition and knee joint morphology: data from the Osteoarthritis Initiative.

Joseph GB, Nevitt MC, McCulloch CE, Neumann J, Lynch JA, Heilmeier U, Lane NE, Link TM.

Osteoarthritis Cartilage. 2018 May 23. pii: S1063-4584(18)31284-6. doi: 10.1016/j.joca.2018.04.019. [Epub ahead of print]


Does the intensity of daily walking matter for protecting against the development of a slow gait speed in people with or at high risk of knee osteoarthritis? An observational study.

Fenton SAM, Neogi T, Dunlop D, Nevitt M, Doherty M, Duda JL, Klocke R, Abhishek A, Rushton A, Zhang W, Lewis CE, Torner J, Kitas G, White DK; Multicenter Osteoarthritis Group.

Osteoarthritis Cartilage. 2018 May 2. pii: S1063-4584(18)31227-5. doi: 10.1016/j.joca.2018.04.015. [Epub ahead of print]


Running does not increase symptoms or structural progression in people with knee osteoarthritis: data from the osteoarthritis initiative.

Lo GH, Musa SM, Driban JB, Kriska AM, McAlindon TE, Souza RB, Petersen NJ, Storti KL, Eaton CB, Hochberg MC, Jackson RD, Kwoh CK, Nevitt MC, Suarez-Almazor ME.

Clin Rheumatol. 2018 May 4. doi: 10.1007/s10067-018-4121-3. [Epub ahead of print]


Leg Length Inequality and Hip Osteoarthritis in the Multicenter Osteoarthritis Study and the Osteoarthritis Initiative.

Kim C, Nevitt M, Guermazi A, Niu J, Clancy M, Tolstykh I, Jungmann PM, Lane NE, Segal NA, Harvey WF, Lewis CE, Felson DT.

Arthritis Rheumatol. 2018 Apr 26. doi: 10.1002/art.40537. [Epub ahead of print]


Type 2 diabetes patients have accelerated cartilage matrix degeneration compared to diabetes free controls: data from the Osteoarthritis Initiative.

Neumann J, Hofmann FC, Heilmeier U, Ashmeik W, Tang K, Gersing AS, Schwaiger BJ, Nevitt MC, Joseph GB, Lane NE, McCulloch CE, Link TM.

Osteoarthritis Cartilage. 2018 Jun;26(6):751-761. doi: 10.1016/j.joca.2018.03.010. Epub 2018 Mar 29.


Periarticular bone predicts knee osteoarthritis progression: Data from the Osteoarthritis Initiative.

Lo GH, Schneider E, Driban JB, Price LL, Hunter DJ, Eaton CB, Hochberg MC, Jackson RD, Kwoh CK, Nevitt MC, Lynch JA, McAlindon TE; OAI Investigators Group.

Semin Arthritis Rheum. 2018 Jan 31. pii: S0049-0172(17)30089-6. doi: 10.1016/j.semarthrit.2018.01.008. [Epub ahead of print]


Relation of meniscus pathology to prevalence and worsening of patellofemoral joint osteoarthritis: the Multicenter Osteoarthritis Study.

Hart HF, Crossley KM, Felson D, Jarraya M, Guermazi A, Roemer F, Lewis CE, Torner J, Nevitt M, Stefanik JJ.

Osteoarthritis Cartilage. 2018 Jul;26(7):912-919. doi: 10.1016/j.joca.2017.11.017. Epub 2018 Feb 7.


Harmonising measures of knee and hip osteoarthritis in population-based cohort studies: an international study.

Leyland KM, Gates LS, Nevitt M, Felson D, Bierma-Zeinstra SM, Conaghan PG, Engebretsen L, Hochberg M, Hunter DJ, Jones G, Jordan JM, Judge A, Lohmander LS, Roos EM, Sanchez-Santos MT, Yoshimura N, van Meurs JBJ, Batt ME, Newton J, Cooper C, Arden NK.

Osteoarthritis Cartilage. 2018 Jul;26(7):872-879. doi: 10.1016/j.joca.2018.01.024. Epub 2018 Feb 7.


Lower Quadriceps Rate of Force Development Is Associated With Worsening Physical Function in Adults With or at Risk for Knee Osteoarthritis: 36-Month Follow-Up Data From the Osteoarthritis Initiative.

Hu B, Skou ST, Wise BL, Williams GN, Nevitt MC, Segal NA.

Arch Phys Med Rehabil. 2018 Jul;99(7):1352-1359. doi: 10.1016/j.apmr.2017.12.027. Epub 2018 Jan 31.


Radiographic Knee Osteoarthritis and Knee Pain: Cross-sectional study from Five Different Racial/Ethnic Populations.

Wang K, Kim HA, Felson DT, Xu L, Kim DH, Nevitt MC, Yoshimura N, Kawaguchi H, Lin J, Kang X, Zhang Y.

Sci Rep. 2018 Jan 22;8(1):1364. doi: 10.1038/s41598-018-19470-3.


Daily Social Interactions and the Biological Stress Response: Are There Age Differences in Links Between Social Interactions and Alpha-Amylase?

Birditt KS, Tighe LA, Nevitt MR, Zarit SH.

Gerontologist. 2017 Dec 12. doi: 10.1093/geront/gnx168. [Epub ahead of print]


Tool for osteoarthritis risk prediction (TOARP) over 8 years using baseline clinical data, X-ray, and MRI: Data from the osteoarthritis initiative.

Joseph GB, McCulloch CE, Nevitt MC, Neumann J, Gersing AS, Kretzschmar M, Schwaiger BJ, Lynch JA, Heilmeier U, Lane NE, Link TM.

J Magn Reson Imaging. 2018 Jun;47(6):1517-1526. doi: 10.1002/jmri.25892. Epub 2017 Nov 16.


Relationship of knee pain to time in moderate and light physical activities: Data from Osteoarthritis Initiative.

Song J, Chang AH, Chang RW, Lee J, Pinto D, Hawker G, Nevitt M, Dunlop DD.

Semin Arthritis Rheum. 2018 Apr;47(5):683-688. doi: 10.1016/j.semarthrit.2017.10.005. Epub 2017 Oct 9.


Predictive Validity of Radiographic Trabecular Bone Texture in Knee Osteoarthritis: The Osteoarthritis Research Society International/Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium.

Kraus VB, Collins JE, Charles HC, Pieper CF, Whitley L, Losina E, Nevitt M, Hoffmann S, Roemer F, Guermazi A, Hunter DJ; OA Biomarkers Consortium.

Arthritis Rheumatol. 2018 Jan;70(1):80-87. doi: 10.1002/art.40348. Epub 2017 Dec 15.


Association of weight change with progression of meniscal intrasubstance degeneration over 48 months: Data from the Osteoarthritis Initiative.

Guimaraes JB, Nevitt MC, McCulloch CE, Schwaiger BJ, Gersing AS, Facchetti L, Bucknor MD, Chanchek N, Liu F, Joseph GB, Link TM.

Eur Radiol. 2018 Mar;28(3):953-962. doi: 10.1007/s00330-017-5054-y. Epub 2017 Oct 6.


Objectively Measured Physical Activity and Risk of Knee Osteoarthritis.

Qin J, Barbour KE, Nevitt MC, Helmick CG, Hootman JM, Murphy LB, Cauley JA, Dunlop DD.

Med Sci Sports Exerc. 2018 Feb;50(2):277-283. doi: 10.1249/MSS.0000000000001433.


Hyperintense signal alteration in the suprapatellar fat pad on MRI is associated with degeneration of the patellofemoral joint over 48 months: data from the Osteoarthritis Initiative.

Schwaiger BJ, Mbapte Wamba J, Gersing AS, Nevitt MC, Facchetti L, McCulloch CE, Link TM.

Skeletal Radiol. 2018 Mar;47(3):329-339. doi: 10.1007/s00256-017-2771-x. Epub 2017 Sep 24.


DXA-derived hip shape is related to osteoarthritis: findings from in the MrOS cohort.

Faber BG, Baird D, Gregson CL, Gregory JS, Barr RJ, Aspden RM, Lynch J, Nevitt MC, Lane NE, Orwoll E, Tobias JH; Osteoporotic Fractures in Men (MrOS) Study Research Group.

Osteoarthritis Cartilage. 2017 Dec;25(12):2031-2038. doi: 10.1016/j.joca.2017.09.006. Epub 2017 Sep 21.


Is synovitis detected on non-contrast-enhanced magnetic resonance imaging associated with serum biomarkers and clinical signs of effusion? Data from the Osteoarthritis Initiative.

Deveza LA, Kraus VB, Collins JE, Guermazi A, Roemer FW, Nevitt MC, Hunter DJ.

Scand J Rheumatol. 2018 May;47(3):235-242. doi: 10.1080/03009742.2017.1340511. Epub 2017 Sep 20.


Conservatively treated knee injury is associated with knee cartilage matrix degeneration measured with MRI-based T2 relaxation times: data from the osteoarthritis initiative.

Hofmann FC, Neumann J, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Link TM.

Skeletal Radiol. 2018 Jan;47(1):93-106. doi: 10.1007/s00256-017-2759-6. Epub 2017 Aug 29.


Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative.

Wirth W, Hunter DJ, Nevitt MC, Sharma L, Kwoh CK, Ladel C, Eckstein F.

Osteoarthritis Cartilage. 2017 Dec;25(12):2063-2071. doi: 10.1016/j.joca.2017.08.005. Epub 2017 Aug 31.


Varus Thrust and Incident and Progressive Knee Osteoarthritis.

Sharma L, Chang AH, Jackson RD, Nevitt M, Moisio KC, Hochberg M, Eaton C, Kwoh CK, Almagor O, Cauley J, Chmiel JS.

Arthritis Rheumatol. 2017 Nov;69(11):2136-2143. doi: 10.1002/art.40224.


Affect and Incident Participation Restriction in Adults With Knee Osteoarthritis.

Vaughan MW, LaValley MP, Felson DT, Orsmond GI, Niu J, Lewis CE, Segal NA, Nevitt MC, Keysor JJ.

Arthritis Care Res (Hoboken). 2018 Apr;70(4):542-549. doi: 10.1002/acr.23308. Epub 2018 Feb 18.


Is superolateral Hoffa's fat pad hyperintensity a marker of local patellofemoral joint disease? - The MOST study.

Jarraya M, Guermazi A, Felson DT, Roemer FW, Nevitt MC, Torner J, Lewis CE, Stefanik JJ.

Osteoarthritis Cartilage. 2017 Sep;25(9):1459-1467. doi: 10.1016/j.joca.2017.05.020. Epub 2017 Jun 9.


Is the atrophic phenotype of tibiofemoral osteoarthritis associated with faster progression of disease? The MOST study.

Crema MD, Felson DT, Guermazi A, Nevitt MC, Niu J, Lynch JA, Marra MD, Torner J, Lewis CE, Roemer FW.

Osteoarthritis Cartilage. 2017 Oct;25(10):1647-1653. doi: 10.1016/j.joca.2017.05.019. Epub 2017 Jun 9.


Association of diabetes mellitus and biochemical knee cartilage composition assessed by T2 relaxation time measurements: Data from the osteoarthritis initiative.

Chanchek N, Gersing AS, Schwaiger BJ, Nevitt MC, Neumann J, Joseph GB, Lane NE, Zarnowski J, Hofmann FC, Heilmeier U, McCulloch CE, Link TM.

J Magn Reson Imaging. 2018 Feb;47(2):380-390. doi: 10.1002/jmri.25766. Epub 2017 May 26.


Associations of Musculoskeletal Pain With Mobility in Older Adults: Potential Cerebral Mechanisms.

Cruz-Almeida Y, Rosso A, Marcum Z, Harris T, Newman AB, Nevitt M, Satterfield S, Yaffe K, Rosano C; Health ABC Study.

J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1270-1276. doi: 10.1093/gerona/glx084.


Is Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage among Obese and Overweight Patients as Assessed with MR Imaging over 48 Months? Data from the Osteoarthritis Initiative.

Gersing AS, Schwaiger BJ, Nevitt MC, Joseph GB, Chanchek N, Guimaraes JB, Mbapte Wamba J, Facchetti L, McCulloch CE, Link TM.

Radiology. 2017 Aug;284(2):508-520. doi: 10.1148/radiol.2017161005. Epub 2017 May 2.


Modeling the shape and composition of the human body using dual energy X-ray absorptiometry images.

Shepherd JA, Ng BK, Fan B, Schwartz AV, Cawthon P, Cummings SR, Kritchevsky S, Nevitt M, Santanasto A, Cootes TF.

PLoS One. 2017 Apr 19;12(4):e0175857. doi: 10.1371/journal.pone.0175857. eCollection 2017.


The Effect of Widespread Pain on Knee Pain Worsening, Incident Knee Osteoarthritis (OA), and Incident Knee Pain: The Multicenter OA (MOST) Study.

Carlesso LC, Niu J, Segal NA, Frey-Law LA, Lewis CE, Nevitt MC, Neogi T.

J Rheumatol. 2017 Apr;44(4):493-498. doi: 10.3899/jrheum.160853. Epub 2017 Mar 1.


Knee tissue lesions and prediction of incident knee osteoarthritis over 7 years in a cohort of persons at higher risk.

Sharma L, Hochberg M, Nevitt M, Guermazi A, Roemer F, Crema MD, Eaton C, Jackson R, Kwoh K, Cauley J, Almagor O, Chmiel JS.

Osteoarthritis Cartilage. 2017 Jul;25(7):1068-1075. doi: 10.1016/j.joca.2017.02.788. Epub 2017 Feb 14.


Medial femur T2 Z-scores predict the probability of knee structural worsening over 4-8 years: Data from the osteoarthritis initiative.

Joseph GB, McCulloch CE, Nevitt MC, Gersing AS, Schwaiger BJ, Kretzschmar M, Heilmeier U, Link TM.

J Magn Reson Imaging. 2017 Oct;46(4):1128-1136. doi: 10.1002/jmri.25662. Epub 2017 Feb 16.


Quantitative measurement of medial femoral knee cartilage volume - analysis of the OA Biomarkers Consortium FNIH Study cohort.

Schaefer LF, Sury M, Yin M, Jamieson S, Donnell I, Smith SE, Lynch JA, Nevitt MC, Duryea J.

Osteoarthritis Cartilage. 2017 Jul;25(7):1107-1113. doi: 10.1016/j.joca.2017.01.010. Epub 2017 Jan 30.


Perceived Community Environmental Factors and Risk of Five-Year Participation Restriction Among Older Adults With or at Risk of Knee Osteoarthritis.

Vaughan MW, Felson DT, LaValley MP, Orsmond GI, Niu J, Lewis CE, Segal NA, Nevitt MC, Keysor JJ.

Arthritis Care Res (Hoboken). 2017 Jul;69(7):952-958. doi: 10.1002/acr.23085. Epub 2017 Jun 2.


Varus thrust during walking and the risk of incident and worsening medial tibiofemoral MRI lesions: the Multicenter Osteoarthritis Study.

Wink AE, Gross KD, Brown CA, Guermazi A, Roemer F, Niu J, Torner J, Lewis CE, Nevitt MC, Tolstykh I, Sharma L, Felson DT.

Osteoarthritis Cartilage. 2017 Jun;25(6):839-845. doi: 10.1016/j.joca.2017.01.005. Epub 2017 Jan 16.


Degeneration in ACL Injured Knees with and without Reconstruction in Relation to Muscle Size and Fat Content-Data from the Osteoarthritis Initiative.

Jungmann PM, Baum T, Nevitt MC, Nardo L, Gersing AS, Lane NE, McCulloch CE, Rummeny EJ, Link TM.

PLoS One. 2016 Dec 5;11(12):e0166865. doi: 10.1371/journal.pone.0166865. eCollection 2016.


Association of Serum Klotho with Loss of Bone Mineral Density and Fracture Risk in Older Adults.

Chalhoub D, Marques E, Meirelles O, Semba RD, Ferrucci L, Satterfield S, Nevitt M, Cauley JA, Harris T; Health ABC Study.

J Am Geriatr Soc. 2016 Dec;64(12):e304-e308. doi: 10.1111/jgs.14661. Epub 2016 Dec 2.


A Prospective Study of Back Pain and Risk of Falls Among Older Community-dwelling Men.

Marshall LM, Litwack-Harrison S, Makris UE, Kado DM, Cawthon PM, Deyo RA, Carlson NL, Nevitt MC; Osteoporotic Fractures in Men Study (MrOS) Research Group.

J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1264-1269. doi: 10.1093/gerona/glw227.


Semi-quantitative MRI biomarkers of knee osteoarthritis progression in the FNIH biomarkers consortium cohort - Methodologic aspects and definition of change.

Roemer FW, Guermazi A, Collins JE, Losina E, Nevitt MC, Lynch JA, Katz JN, Kwoh CK, Kraus VB, Hunter DJ.

BMC Musculoskelet Disord. 2016 Nov 10;17(1):466.


Brief Report: Partial- and Full-Thickness Focal Cartilage Defects Contribute Equally to Development of New Cartilage Damage in Knee Osteoarthritis: The Multicenter Osteoarthritis Study.

Guermazi A, Hayashi D, Roemer FW, Niu J, Quinn EK, Crema MD, Nevitt MC, Torner J, Lewis CE, Felson DT.

Arthritis Rheumatol. 2017 Mar;69(3):560-564. doi: 10.1002/art.39970.


Effect of Knee Extensor Strength on Incident Radiographic and Symptomatic Knee Osteoarthritis in Individuals With Meniscal Pathology: Data From the Multicenter Osteoarthritis Study.

Thorlund JB, Felson DT, Segal NA, Nevitt MC, Niu J, Neogi T, Lewis CE, Guermazi A, Roemer F, Englund M.

Arthritis Care Res (Hoboken). 2016 Nov;68(11):1640-1646. doi: 10.1002/acr.22889. Epub 2016 Oct 1.


Association Between Biochemical Markers of Bone Turnover and Bone Changes on Imaging: Data From the Osteoarthritis Initiative.

Deveza LA, Kraus VB, Collins JE, Guermazi A, Roemer FW, Bowes M, Nevitt MC, Ladel C, Hunter DJ.

Arthritis Care Res (Hoboken). 2017 Aug;69(8):1179-1191. doi: 10.1002/acr.23121. Epub 2017 Jul 10.


Evaluation of Chondrocalcinosis and Associated Knee Joint Degeneration Using MR Imaging: Data from the Osteoarthritis Initiative.

Gersing AS, Schwaiger BJ, Heilmeier U, Joseph GB, Facchetti L, Kretzschmar M, Lynch JA, McCulloch CE, Nevitt MC, Steinbach LS, Link TM.

Eur Radiol. 2017 Jun;27(6):2497-2506. doi: 10.1007/s00330-016-4608-8. Epub 2016 Oct 4.


Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.

Castaño-Betancourt MC, Evans DS, Ramos YF, Boer CG, Metrustry S, Liu Y, den Hollander W, van Rooij J, Kraus VB, Yau MS, Mitchell BD, Muir K, Hofman A, Doherty M, Doherty S, Zhang W, Kraaij R, Rivadeneira F, Barrett-Connor E, Maciewicz RA, Arden N, Nelissen RG, Kloppenburg M, Jordan JM, Nevitt MC, Slagboom EP, Hart DJ, Lafeber F, Styrkarsdottir U, Zeggini E, Evangelou E, Spector TD, Uitterlinden AG, Lane NE, Meulenbelt I, Valdes AM, van Meurs JB.

PLoS Genet. 2016 Oct 4;12(10):e1006260. doi: 10.1371/journal.pgen.1006260. eCollection 2016 Oct.


Genome-Wide Association Study of Radiographic Knee Osteoarthritis in North American Caucasians.

Yau MS, Yerges-Armstrong LM, Liu Y, Lewis CE, Duggan DJ, Renner JB, Torner J, Felson DT, McCulloch CE, Kwoh CK, Nevitt MC, Hochberg MC, Mitchell BD, Jordan JM, Jackson RD.

Arthritis Rheumatol. 2017 Feb;69(2):343-351. doi: 10.1002/art.39932.


Knee Pain and Structural Damage as Risk Factors for Incident Widespread Pain: Data From the Multicenter Osteoarthritis Study.

Carlesso LC, Segal NA, Curtis JR, Wise BL, Frey Law L, Nevitt M, Neogi T.

Arthritis Care Res (Hoboken). 2017 Jun;69(6):826-832. doi: 10.1002/acr.23086. Epub 2017 May 8.


Multiple Nonspecific Sites of Joint Pain Outside the Knees Develop in Persons With Knee Pain.

Felson DT, Niu J, Quinn EK, Neogi T, Lewis CL, Lewis CE, Frey Law L, McCulloch C, Nevitt M, LaValley M.

Arthritis Rheumatol. 2017 Feb;69(2):335-342. doi: 10.1002/art.39848. Erratum in: Arthritis Rheumatol. 2017 Apr;69(4):862.


The Association of Vibratory Perception and Muscle Strength With the Incidence and Worsening of Knee Instability: The Multicenter Osteoarthritis Study.

Shakoor N, Felson DT, Niu J, Nguyen US, Segal NA, Singh JA, Nevitt MC.

Arthritis Rheumatol. 2017 Jan;69(1):94-102. doi: 10.1002/art.39821. Epub 2016 Dec 7.


The relationship between meniscal pathology and osteoarthritis depends on the type of meniscal damage visible on magnetic resonance images: data from the Osteoarthritis Initiative.

Antony B, Driban JB, Price LL, Lo GH, Ward RJ, Nevitt M, Lynch J, Eaton CB, Ding C, McAlindon TE.

Osteoarthritis Cartilage. 2017 Jan;25(1):76-84. doi: 10.1016/j.joca.2016.08.004. Epub 2016 Aug 15.


Comparison of tibiofemoral joint space width measurements from standing CT and fixed flexion radiography.

Segal NA, Frick E, Duryea J, Nevitt MC, Niu J, Torner JC, Felson DT, Anderson DD.

J Orthop Res. 2017 Jul;35(7):1388-1395. doi: 10.1002/jor.23387. Epub 2017 Apr 21.

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