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Items: 1 to 50 of 140

1.

Exploring the Waveform Characteristics of Tidal Breathing Carbon Dioxide, Measured Using the N-Tidal C Device in Different Breathing Conditions (The General Breathing Record Study): Protocol for an Observational, Longitudinal Study.

Neville DM, Rupani H, Kalra PR, Adeniji K, Quint M, De Vos R, Begum S, Mottershaw M, Fogg C, Jones TL, Lanning E, Bassett P, Chauhan AJ.

JMIR Res Protoc. 2018 May 24;7(5):e140. doi: 10.2196/resprot.9767.

2.

Diagnosis and treatment of severe asthma: a phenotype-based approach.

Jones TL, Neville DM, Chauhan AJ.

Clin Med (Lond). 2018 Apr 1;18(Suppl 2):s36-s40. doi: 10.7861/clinmedicine.18-2-s36.

PMID:
29700091
3.

The Ellipta® in asthma and chronic obstructive pulmonary disease: device characteristics and patient acceptability.

Jones TL, Neville DM, Chauhan AJ.

Ther Deliv. 2018 Feb 1;9(3):169-176. doi: 10.4155/tde-2017-0103.

PMID:
29424288
5.

Resimmune, an anti-CD3ε recombinant immunotoxin, induces durable remissions in patients with cutaneous T-cell lymphoma.

Frankel AE, Woo JH, Ahn C, Foss FM, Duvic M, Neville PH, Neville DM.

Haematologica. 2015 Jun;100(6):794-800. doi: 10.3324/haematol.2015.123711. Epub 2015 Mar 20.

6.

A pilot open-label trial of minocycline in patients with autism and regressive features.

Pardo CA, Buckley A, Thurm A, Lee LC, Azhagiri A, Neville DM, Swedo SE.

J Neurodev Disord. 2013;5(1):9. doi: 10.1186/1866-1955-5-9. Epub 2013 Apr 8.

7.

A truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin.

Peraino JS, Schenk M, Zhang H, Li G, Hermanrud CE, Neville DM Jr, Sachs DH, Huang CA, Duran-Struuck R, Wang Z.

J Immunol Methods. 2013 May 31;391(1-2):103-11. doi: 10.1016/j.jim.2013.02.015. Epub 2013 Mar 5.

8.

Development of a diphtheria toxin based antiporcine CD3 recombinant immunotoxin.

Wang Z, Duran-Struuck R, Crepeau R, Matar A, Hanekamp I, Srinivasan S, Neville DM Jr, Sachs DH, Huang CA.

Bioconjug Chem. 2011 Oct 19;22(10):2014-20. doi: 10.1021/bc200230h. Epub 2011 Sep 9.

9.

Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials.

Woo JH, Lee YJ, Neville DM, Frankel AE.

Methods Mol Biol. 2010;651:157-75. doi: 10.1007/978-1-60761-786-0_10.

PMID:
20686966
10.

Anti-CD3 recombinant diphtheria immunotoxin therapy of cutaneous T cell lymphoma.

Frankel AE, Zuckero SL, Mankin AA, Grable M, Mitchell K, Lee YJ, Neville DM, Woo JH.

Curr Drug Targets. 2009 Feb;10(2):104-9. Review.

PMID:
19199905
11.

Retraction: Peritransplant tolerance induction with anti-CD3-immunotoxin: a matter of proinflammatory cytokine control.

Thomas JM, Contreras JL, Wang PX, Eckhoff DE, Asiedu C, Hubbard WJ, Cartner S, Thomas FT, Robbin ML, Nadler S, Cook WJ, Sharff J, Neville DM Jr, Shiloach J.

Transplantation. 2008 Mar 27;85(6):920. doi: 10.1097/TP.0b013e318172dbe0. No abstract available.

PMID:
18360278
12.

Preclinical studies in rats and squirrel monkeys for safety evaluation of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1).

Woo JH, Bour SH, Dang T, Lee YJ, Park SK, Andreas E, Kang SH, Liu JS, Neville DM Jr, Frankel AE.

Cancer Immunol Immunother. 2008 Aug;57(8):1225-39. doi: 10.1007/s00262-008-0457-x. Epub 2008 Feb 7.

PMID:
18256829
13.

GMP production and characterization of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1) for phase I/II clinical trials.

Woo JH, Liu JS, Kang SH, Singh R, Park SK, Su Y, Ortiz J, Neville DM Jr, Willingham MC, Frankel AE.

Protein Expr Purif. 2008 Mar;58(1):1-11. Epub 2007 Nov 22.

PMID:
18160309
14.

A fold-back single-chain diabody format enhances the bioactivity of an anti-monkey CD3 recombinant diphtheria toxin-based immunotoxin.

Kim GB, Wang Z, Liu YY, Stavrou S, Mathias A, Goodwin KJ, Thomas JM, Neville DM.

Protein Eng Des Sel. 2007 Sep;20(9):425-32. Epub 2007 Aug 10.

PMID:
17693455
15.

Improvement of a recombinant anti-monkey anti-CD3 diphtheria toxin based immunotoxin by yeast display affinity maturation of the scFv.

Wang Z, Kim GB, Woo JH, Liu YY, Mathias A, Stavrou S, Neville DM Jr.

Bioconjug Chem. 2007 May-Jun;18(3):947-55. Epub 2007 Mar 13.

PMID:
17352456
16.

Polymorphisms of CD3epsilon in cynomolgus and rhesus monkeys and their relevance to anti-CD3 antibodies and immunotoxins.

Liu YY, Wang Z, Thomas J, Goodwin KJ, Stavrou S, Neville DM Jr.

Immunol Cell Biol. 2007 Jul;85(5):357-62. Epub 2007 Feb 27.

PMID:
17325695
17.

Retraction: Durable donor-specific T and B cell tolerance in rhesus macaques induced with peritransplantation anti-CD3 immunotoxin and deoxyspergualin: absence of chronic allograft nephropathy.

Thomas JM, Eckhoff DE, Contreras JL, Thomas FT, Neville DM Jr, Lobashevsky A, Hubbard WJ, Cook WJ.

Transplantation. 2006 Aug 27;82(4):577. No abstract available.

PMID:
16926605
18.

Letter of retraction.

Asiedu C, Goodwin K, Balgansuren G, Jenkins SM, Le Bas-Bernardet S, Jargal U, Thomas J, Neville DM Jr.

J Immunol. 2006 Aug 1;177(3):2023. No abstract available.

19.

Stable multilineage chimerism without graft versus host disease following nonmyeloablative haploidentical hematopoietic cell transplantation.

Cina RA, Wikiel KJ, Lee PW, Cameron AM, Hettiarachy S, Rowland H, Goodrich J, Colby C, Spitzer TR, Neville DM Jr, Huang CA.

Transplantation. 2006 Jun 27;81(12):1677-85.

PMID:
16794534
20.

Vascularized thymic lobe transplantation in a pig-to-baboon model: a novel strategy for xenogeneic tolerance induction and T-cell reconstitution.

Yamamoto S, Lavelle JM, Vagefi PA, Arakawa H, Samelson-Jones E, Moran S, Teranishi K, Kamano C, Fishman J, Awwad M, Neville DM, Shimizu A, Sykes M, Sachs DH, Yamada K.

Transplantation. 2005 Dec 27;80(12):1783-90.

PMID:
16378075
22.
24.

A new yeast display vector permitting free scFv amino termini can augment ligand binding affinities.

Wang Z, Mathias A, Stavrou S, Neville DM Jr.

Protein Eng Des Sel. 2005 Jul;18(7):337-43. Epub 2005 Jun 23.

PMID:
15976011
25.

Risk factors for the development of post-transplant lymphoproliferative disorder in a large animal model.

Cho PS, Mueller NJ, Cameron AM, Cina RA, Coburn RC, Hettiaratchy S, Melendy E, Neville DM Jr, Patience C, Fishman JA, Sachs DH, Huang CA.

Am J Transplant. 2004 Aug;4(8):1274-82.

26.

Increasing secretion of a bivalent anti-T-cell immunotoxin by Pichia pastoris.

Woo JH, Liu YY, Stavrou S, Neville DM Jr.

Appl Environ Microbiol. 2004 Jun;70(6):3370-6.

27.
28.

Tolerance to composite tissue allografts across a major histocompatibility barrier in miniature swine.

Hettiaratchy S, Melendy E, Randolph MA, Coburn RC, Neville DM Jr, Sachs DH, Huang CA, Lee WP.

Transplantation. 2004 Feb 27;77(4):514-21.

PMID:
15084927
29.
30.

Immunotoxin therapy of hematologic malignancies.

Frankel AE, Neville DM, Bugge TA, Kreitman RJ, Leppla SH.

Semin Oncol. 2003 Aug;30(4):545-57. Review.

PMID:
12939723
32.

Stable alpha- and beta-islet cell function after tolerance induction to pancreatic islet allografts in diabetic primates.

Contreras JL, Jenkins S, Eckhoff DE, Hubbard WJ, Lobashevsky A, Bilbao G, Thomas FT, Neville DM Jr, Thomas JM.

Am J Transplant. 2003 Feb;3(2):128-38.

33.

Xenogeneic thymus transplantation in a pig-to-baboon model.

Wu A, Yamada K, Neville DM, Awwad M, Wain JC, Shimizu A, Gojo S, Kitamura H, Colvin RB, Cooper DK, Sykes M, Sachs DH.

Transplantation. 2003 Feb 15;75(3):282-91.

PMID:
12589146
34.

Variable relationship between chimerism and tolerance after hematopoietic cell transplantation without myelosuppressive conditioning.

Gleit ZL, Fuchimoto Y, Yamada K, Melendy E, Scheier-Dolberg R, Monajati L, Coburn RC, Neville DM Jr, Sachs DH, Huang CA.

Transplantation. 2002 Dec 15;74(11):1535-44.

PMID:
12490786
35.

Gene optimization is necessary to express a bivalent anti-human anti-T cell immunotoxin in Pichia pastoris.

Woo JH, Liu YY, Mathias A, Stavrou S, Wang Z, Thompson J, Neville DM Jr.

Protein Expr Purif. 2002 Jul;25(2):270-82.

PMID:
12135560
36.

Improved binding of a bivalent single-chain immunotoxin results in increased efficacy for in vivo T-cell depletion.

Thompson J, Stavrou S, Weetall M, Hexham JM, Digan ME, Wang Z, Woo JH, Yu Y, Mathias A, Liu YY, Ma S, Gordienko I, Lake P, Neville DM Jr.

Protein Eng. 2001 Dec;14(12):1035-41.

PMID:
11809934
37.

Chimeric fusion proteins--diphtheria toxin-based.

Frankel AE, Powell BL, Vallera DA, Neville DM Jr.

Curr Opin Investig Drugs. 2001 Sep;2(9):1294-301. Review.

PMID:
11717818
38.

Influence of relative binding affinity on efficacy in a panel of anti-CD3 scFv immunotoxins.

Hexham JM, Dudas D, Hugo R, Thompson J, King V, Dowling C, Neville DM Jr, Digan ME, Lake P.

Mol Immunol. 2001 Sep;38(5):397-408.

PMID:
11684296
39.

Successful reversal of streptozotocin-induced diabetes with stable allogeneic islet function in a preclinical model of type 1 diabetes.

Thomas JM, Contreras JL, Smyth CA, Lobashevsky A, Jenkins S, Hubbard WJ, Eckhoff DE, Stavrou S, Neville DM Jr, Thomas FT.

Diabetes. 2001 Jun;50(6):1227-36.

40.

Phenotypic and functional analysis of T-cell recovery after anti-CD3 immunotoxin treatment for tolerance induction in rhesus macaques.

Hubbard WJ, Moore JK, Contreras JL, Smyth CA, Chen ZW, Lobashevsky AL, Nagata K, Neville DM Jr, Thomas JM.

Hum Immunol. 2001 May;62(5):479-87.

PMID:
11334671
41.

Effects of xenogeneic thymic transplantation in baboons.

Wu A, Yamada K, Awwad M, Kitamura H, Wain J, Neville DM, Cooper DK, Sykes M, Sachs DH.

Transplant Proc. 2001 Feb-Mar;33(1-2):766. No abstract available.

PMID:
11267060
43.

Expression of an anti-CD3 single-chain immunotoxin with a truncated diphtheria toxin in a mutant CHO cell line.

Liu YY, Gordienko I, Mathias A, Ma S, Thompson J, Woo JH, Neville DM Jr.

Protein Expr Purif. 2000 Jul;19(2):304-11.

PMID:
10873546
44.

Mixed chimerism and tolerance without whole body irradiation in a large animal model.

Fuchimoto Y, Huang CA, Yamada K, Shimizu A, Kitamura H, Colvin RB, Ferrara V, Murphy MC, Sykes M, White-Scharf M, Neville DM Jr, Sachs DH.

J Clin Invest. 2000 Jun;105(12):1779-89.

45.

Long-term functional islet mass and metabolic function after xenoislet transplantation in primates.

Contreras JL, Eckhoff DE, Cartner S, Bilbao G, Ricordi C, Neville DM Jr, Thomas FT, Thomas JM.

Transplantation. 2000 Jan 27;69(2):195-201.

PMID:
10670626
46.

Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model.

Huang CA, Fuchimoto Y, Scheier-Dolberg R, Murphy MC, Neville DM Jr, Sachs DH.

J Clin Invest. 2000 Jan;105(2):173-81.

47.

Peritransplant tolerance induction in macaques: early events reflecting the unique synergy between immunotoxin and deoxyspergualin.

Thomas JM, Contreras JL, Jiang XL, Eckhoff DE, Wang PX, Hubbard WJ, Lobashevsky AL, Wang W, Asiedu C, Stavrou S, Cook WJ, Robbin ML, Thomas FT, Neville DM Jr.

Transplantation. 1999 Dec 15;68(11):1660-73. Retraction in: Marchase RB. Transplantation. 2008 Aug 15;86(3):482.

PMID:
10609942
48.

In vivo T cell depletion in miniature swine using the swine CD3 immunotoxin, pCD3-CRM9.

Huang CA, Yamada K, Murphy MC, Shimizu A, Colvin RB, Neville DM Jr, Sachs DH.

Transplantation. 1999 Sep 27;68(6):855-60.

PMID:
10515387
49.

Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients.

Contreras JL, Eckhoff DE, Cartner S, Frenette L, Thomas FT, Robbin ML, Neville DM Jr, Thomas JM.

Transplantation. 1999 Jul 27;68(2):215-9. Retraction in: Marchase RB. Transplantation. 2008 Aug 15;86(3):482.

PMID:
10440390
50.

Reversal of naturally occuring diabetes in primates by unmodified islet xenografts without chronic immunosuppression.

Thomas FT, Ricordi C, Contreras JL, Hubbard WJ, Jiang XL, Eckhoff DE, Cartner S, Bilbao G, Neville DM Jr, Thomas JM.

Transplantation. 1999 Mar 27;67(6):846-54.

PMID:
10199733

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