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Items: 39


Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers.

Stubbe M, Mai J, Paulus C, Stubbe HC, Berscheminski J, Karimi M, Hofmann S, Weber E, Hadian K, Hay R, Groitl P, Nevels M, Dobner T, Schreiner S.

mBio. 2020 Mar 17;11(2). pii: e00049-20. doi: 10.1128/mBio.00049-20.


Bright and Early: Inhibiting Human Cytomegalovirus by Targeting Major Immediate-Early Gene Expression or Protein Function.

Adamson CS, Nevels MM.

Viruses. 2020 Jan 16;12(1). pii: E110. doi: 10.3390/v12010110. Review.


Teaching a Health Equity Course at a Midwestern Private University-A Pilot Study.

Braun R, Nevels M, Frey MC.

Int Q Community Health Educ. 2020 Apr;40(3):201-207. doi: 10.1177/0272684X19874974. Epub 2019 Sep 11. No abstract available.


Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.

Dunphy G, Flannery SM, Almine JF, Connolly DJ, Paulus C, Jønsson KL, Jakobsen MR, Nevels MM, Bowie AG, Unterholzner L.

Mol Cell. 2018 Sep 6;71(5):745-760.e5. doi: 10.1016/j.molcel.2018.07.034.


Impact of human cytomegalovirus on glioblastoma cell viability and chemotherapy treatment.

Dos Santos CJ, Ferreira Castro FL, de Aguiar RB, Menezes IG, Santos AC, Paulus C, Nevels M, Carlan da Silva MC.

J Gen Virol. 2018 Sep;99(9):1274-1285. doi: 10.1099/jgv.0.001118. Epub 2018 Jul 27.


Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus.

Wu CC, Jiang X, Wang XZ, Liu XJ, Li XJ, Yang B, Ye HQ, Harwardt T, Jiang M, Xia HM, Wang W, Britt WJ, Paulus C, Nevels M, Luo MH.

J Virol. 2018 Aug 16;92(17). pii: e00340-18. doi: 10.1128/JVI.00340-18. Print 2018 Sep 1.


Launching a Global Network of Virologists: The World Society for Virology (WSV).

Abdel-Moneim AS, Varma A, Pujol FH, Lewis GK, Paweska JT, Romalde JL, Söderlund-Venermo M, Moore MD, Nevels MM, Vakharia VN, Joshi V, Malik YS, Shi Z, Memish ZA.

Intervirology. 2017;60(6):276-277. doi: 10.1159/000488762. Epub 2018 Jun 6. No abstract available.


Modular cell-based platform for high throughput identification of compounds that inhibit a viral interferon antagonist of choice.

Vasou A, Paulus C, Narloch J, Gage ZO, Rameix-Welti MA, Eléouët JF, Nevels M, Randall RE, Adamson CS.

Antiviral Res. 2018 Feb;150:79-92. doi: 10.1016/j.antiviral.2017.10.012. Epub 2017 Oct 14.


Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase.

Liu XJ, Yang B, Huang SN, Wu CC, Li XJ, Cheng S, Jiang X, Hu F, Ming YZ, Nevels M, Britt WJ, Rayner S, Tang Q, Zeng WB, Zhao F, Luo MH.

PLoS Pathog. 2017 Jul 27;13(7):e1006542. doi: 10.1371/journal.ppat.1006542. eCollection 2017 Jul.


ARID3B: a Novel Regulator of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Cycle.

Wood JJ, Boyne JR, Paulus C, Jackson BR, Nevels MM, Whitehouse A, Hughes DJ.

J Virol. 2016 Sep 29;90(20):9543-55. doi: 10.1128/JVI.03262-15. Print 2016 Oct 15.


Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like Response.

Harwardt T, Lukas S, Zenger M, Reitberger T, Danzer D, Übner T, Munday DC, Nevels M, Paulus C.

PLoS Pathog. 2016 Jul 7;12(7):e1005748. doi: 10.1371/journal.ppat.1005748. eCollection 2016 Jul.


The proteome of human cytomegalovirus virions and dense bodies is conserved across different strains.

Büscher N, Paulus C, Nevels M, Tenzer S, Plachter B.

Med Microbiol Immunol. 2015 Jun;204(3):285-93. doi: 10.1007/s00430-015-0397-y. Epub 2015 Mar 3.


Human cytomegalovirus major immediate early 1 protein targets host chromosomes by docking to the acidic pocket on the nucleosome surface.

Mücke K, Paulus C, Bernhardt K, Gerrer K, Schön K, Fink A, Sauer EM, Asbach-Nitzsche A, Harwardt T, Kieninger B, Kremer W, Kalbitzer HR, Nevels M.

J Virol. 2014 Jan;88(2):1228-48. doi: 10.1128/JVI.02606-13. Epub 2013 Nov 13.


Determination of the transforming activities of adenovirus oncogenes.

Speiseder T, Nevels M, Dobner T.

Methods Mol Biol. 2014;1089:105-15. doi: 10.1007/978-1-62703-679-5_8.


Human cytomegalovirus IE1 protein disrupts interleukin-6 signaling by sequestering STAT3 in the nucleus.

Reitsma JM, Sato H, Nevels M, Terhune SS, Paulus C.

J Virol. 2013 Oct;87(19):10763-76. doi: 10.1128/JVI.01197-13. Epub 2013 Jul 31.


Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein.

Zalckvar E, Paulus C, Tillo D, Asbach-Nitzsche A, Lubling Y, Winterling C, Strieder N, Mücke K, Goodrum F, Segal E, Nevels M.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13126-31. doi: 10.1073/pnas.1305548110. Epub 2013 Jul 22.


Snapshots: chromatin control of viral infection.

Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV, Ott M, Margolis D, Nieto A, Nevels M, Parks RJ, Kristie TM.

Virology. 2013 Jan 5;435(1):141-56. doi: 10.1016/j.virol.2012.09.023. Review.


Histone H3 lysine 4 methylation marks postreplicative human cytomegalovirus chromatin.

Nitzsche A, Steinhäusser C, Mücke K, Paulus C, Nevels M.

J Virol. 2012 Sep;86(18):9817-27. doi: 10.1128/JVI.00581-12. Epub 2012 Jul 3.


How to control an infectious bead string: nucleosome-based regulation and targeting of herpesvirus chromatin.

Nevels M, Nitzsche A, Paulus C.

Rev Med Virol. 2011 May;21(3):154-80. doi: 10.1002/rmv.690. Review.


Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-γ.

Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C.

PLoS Pathog. 2011 Apr;7(4):e1002016. doi: 10.1371/journal.ppat.1002016. Epub 2011 Apr 14.


The multi-targeted kinase inhibitor sorafenib inhibits human cytomegalovirus replication.

Michaelis M, Paulus C, Löschmann N, Dauth S, Stange E, Doerr HW, Nevels M, Cinatl J Jr.

Cell Mol Life Sci. 2011 Mar;68(6):1079-90. doi: 10.1007/s00018-010-0510-8. Epub 2010 Aug 30.


The human cytomegalovirus major immediate-early proteins as antagonists of intrinsic and innate antiviral host responses.

Paulus C, Nevels M.

Viruses. 2009 Dec;1(3):760-79. doi: 10.3390/v1030760. Epub 2009 Nov 5.


Chromatinisation of herpesvirus genomes.

Paulus C, Nitzsche A, Nevels M.

Rev Med Virol. 2010 Jan;20(1):34-50. doi: 10.1002/rmv.632. Review.


Physical requirements and functional consequences of complex formation between the cytomegalovirus IE1 protein and human STAT2.

Krauss S, Kaps J, Czech N, Paulus C, Nevels M.

J Virol. 2009 Dec;83(24):12854-70. doi: 10.1128/JVI.01164-09. Epub 2009 Oct 7.


Activation of telomerase in glioma cells by human cytomegalovirus: another piece of the puzzle.

Cinatl J Jr, Nevels M, Paulus C, Michaelis M.

J Natl Cancer Inst. 2009 Apr 1;101(7):441-3. doi: 10.1093/jnci/djp047. Epub 2009 Mar 24. Review. No abstract available.


Temporal dynamics of cytomegalovirus chromatin assembly in productively infected human cells.

Nitzsche A, Paulus C, Nevels M.

J Virol. 2008 Nov;82(22):11167-80. doi: 10.1128/JVI.01218-08. Epub 2008 Sep 10.


Determination of the transforming activities of adenovirus oncogenes.

Nevels M, Dobner T.

Methods Mol Med. 2007;131:187-95.


A human cytomegalovirus antagonist of type I IFN-dependent signal transducer and activator of transcription signaling.

Paulus C, Krauss S, Nevels M.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3840-5. Epub 2006 Feb 23.


Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation.

Nevels M, Paulus C, Shenk T.

Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17234-9. Epub 2004 Nov 30.


"Hit-and-run" transformation by adenovirus oncogenes.

Nevels M, Täuber B, Spruss T, Wolf H, Dobner T.

J Virol. 2001 Apr;75(7):3089-94.


Two distinct activities contribute to the oncogenic potential of the adenovirus type 5 E4orf6 protein.

Nevels M, Rubenwolf S, Spruss T, Wolf H, Dobner T.

J Virol. 2000 Jun;74(11):5168-81.


An ovine adenovirus vector lacks transforming ability in cells that are transformed by AD5 E1A/B sequences.

Xu ZZ, Nevels M, MacAvoy ES, Lockett LJ, Curiel D, Dobner T, Both GW.

Virology. 2000 Apr 25;270(1):162-72.


Quantitation of beta-galactosidase from yeast cells using a chemiluminescent substrate.

Nevels M, Wolf H, Dobner T.

Biotechniques. 1999 Jan;26(1):57-8. No abstract available.


Transforming potential of the adenovirus type 5 E4orf3 protein.

Nevels M, Täuber B, Kremmer E, Spruss T, Wolf H, Dobner T.

J Virol. 1999 Feb;73(2):1591-600.


The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor function.

Nevels M, Rubenwolf S, Spruss T, Wolf H, Dobner T.

Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1206-11.


Structural analysis of the adenovirus type 5 E1B 55-kilodalton-E4orf6 protein complex.

Rubenwolf S, Schütt H, Nevels M, Wolf H, Dobner T.

J Virol. 1997 Feb;71(2):1115-23.

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