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Items: 22

1.

SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.

Ehrenhöfer-Wölfer K, Puchner T, Schwarz C, Rippka J, Blaha-Ostermann S, Strobl U, Hörmann A, Bader G, Kornigg S, Zahn S, Sommergruber W, Schweifer N, Zichner T, Schlattl A, Neumüller RA, Shi J, Vakoc CR, Kögl M, Petronczki M, Kraut N, Pearson MA, Wöhrle S.

Sci Rep. 2019 Aug 12;9(1):11661. doi: 10.1038/s41598-019-48152-x.

2.

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.

Böttcher J, Dilworth D, Reiser U, Neumüller RA, Schleicher M, Petronczki M, Zeeb M, Mischerikow N, Allali-Hassani A, Szewczyk MM, Li F, Kennedy S, Vedadi M, Barsyte-Lovejoy D, Brown PJ, Huber KVM, Rogers CM, Wells CI, Fedorov O, Rumpel K, Zoephel A, Mayer M, Wunberg T, Böse D, Zahn S, Arnhof H, Berger H, Reiser C, Hörmann A, Krammer T, Corcokovic M, Sharps B, Winkler S, Häring D, Cockcroft XL, Fuchs JE, Müllauer B, Weiss-Puxbaum A, Gerstberger T, Boehmelt G, Vakoc CR, Arrowsmith CH, Pearson M, McConnell DB.

Nat Chem Biol. 2019 Aug;15(8):822-829. doi: 10.1038/s41589-019-0310-x. Epub 2019 Jul 8.

PMID:
31285596
3.

Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells.

Lieb S, Blaha-Ostermann S, Kamper E, Rippka J, Schwarz C, Ehrenhöfer-Wölfer K, Schlattl A, Wernitznig A, Lipp JJ, Nagasaka K, van der Lelij P, Bader G, Koi M, Goel A, Neumüller RA, Peters JM, Kraut N, Pearson MA, Petronczki M, Wöhrle S.

Elife. 2019 Mar 25;8. pii: e43333. doi: 10.7554/eLife.43333.

4.

RIOK1 kinase activity is required for cell survival irrespective of MTAP status.

Hörmann A, Hopfgartner B, Köcher T, Corcokovic M, Krammer T, Reiser C, Bader G, Shi J, Ehrenhöfer K, Wöhrle S, Schweifer N, Vakoc CR, Kraut N, Pearson M, Petronczki M, Neumüller RA.

Oncotarget. 2018 Jun 19;9(47):28625-28637. doi: 10.18632/oncotarget.25586. eCollection 2018 Jun 19.

5.

Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop.

Wissel S, Harzer H, Bonnay F, Burkard TR, Neumüller RA, Knoblich JA.

J Cell Biol. 2018 Sep 3;217(9):3285-3300. doi: 10.1083/jcb.201711167. Epub 2018 Jun 29.

6.

A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function.

Wissel S, Kieser A, Yasugi T, Duchek P, Roitinger E, Gokcezade J, Steinmann V, Gaul U, Mechtler K, Förstemann K, Knoblich JA, Neumüller RA.

G3 (Bethesda). 2016 Aug 9;6(8):2467-78. doi: 10.1534/g3.116.028571.

7.

The Transgenic RNAi Project at Harvard Medical School: Resources and Validation.

Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, Namgyal P, Villalta C, Liu LP, Jiang X, Huan-Huan Q, Wang X, Fujiyama A, Toyoda A, Ayers K, Blum A, Czech B, Neumuller R, Yan D, Cavallaro A, Hibbard K, Hall D, Cooley L, Hannon GJ, Lehmann R, Parks A, Mohr SE, Ueda R, Kondo S, Ni JQ, Perrimon N.

Genetics. 2015 Nov;201(3):843-52. doi: 10.1534/genetics.115.180208. Epub 2015 Aug 28.

8.

Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila.

Zeng X, Han L, Singh SR, Liu H, Neumüller RA, Yan D, Hu Y, Liu Y, Liu W, Lin X, Hou SX.

Cell Rep. 2015 Feb 24;10(7):1226-38. doi: 10.1016/j.celrep.2015.01.051. Epub 2015 Feb 19.

9.

RNAi screening comes of age: improved techniques and complementary approaches.

Mohr SE, Smith JA, Shamu CE, Neumüller RA, Perrimon N.

Nat Rev Mol Cell Biol. 2014 Sep;15(9):591-600. doi: 10.1038/nrm3860. Review.

10.

Systematic screen of chemotherapeutics in Drosophila stem cell tumors.

Markstein M, Dettorre S, Cho J, Neumüller RA, Craig-Müller S, Perrimon N.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4530-5. doi: 10.1073/pnas.1401160111. Epub 2014 Mar 10.

11.

A regulatory network of Drosophila germline stem cell self-renewal.

Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, Cooley L, Perrimon N.

Dev Cell. 2014 Feb 24;28(4):459-73. doi: 10.1016/j.devcel.2014.01.020.

12.

Integrating protein-protein interaction networks with phenotypes reveals signs of interactions.

Vinayagam A, Zirin J, Roesel C, Hu Y, Yilmazel B, Samsonova AA, Neumüller RA, Mohr SE, Perrimon N.

Nat Methods. 2014 Jan;11(1):94-9. doi: 10.1038/nmeth.2733. Epub 2013 Nov 17.

13.

Conserved regulators of nucleolar size revealed by global phenotypic analyses.

Neumüller RA, Gross T, Samsonova AA, Vinayagam A, Buckner M, Founk K, Hu Y, Sharifpoor S, Rosebrock AP, Andrews B, Winston F, Perrimon N.

Sci Signal. 2013 Aug 20;6(289):ra70. doi: 10.1126/scisignal.2004145.

14.

Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes.

Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N.

Genetics. 2012 Mar;190(3):931-40. doi: 10.1534/genetics.111.136465. Epub 2011 Dec 14.

15.

Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi.

Neumüller RA, Richter C, Fischer A, Novatchkova M, Neumüller KG, Knoblich JA.

Cell Stem Cell. 2011 May 6;8(5):580-93. doi: 10.1016/j.stem.2011.02.022.

16.

Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila.

Neumüller RA, Perrimon N.

Wiley Interdiscip Rev Syst Biol Med. 2011 Jul-Aug;3(4):471-8. doi: 10.1002/wsbm.127. Epub 2010 Dec 31.

17.

Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer.

Neumüller RA, Knoblich JA.

Genes Dev. 2009 Dec 1;23(23):2675-99. doi: 10.1101/gad.1850809. Review.

18.

Wicked views on stem cell news.

Neumüller RA, Knoblich JA.

Nat Cell Biol. 2009 Jun;11(6):678-9. doi: 10.1038/ncb0609-678. No abstract available.

PMID:
19488057
19.

Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling.

Benetka W, Mehlmer N, Maurer-Stroh S, Sammer M, Koranda M, Neumüller R, Betschinger J, Knoblich JA, Teige M, Eisenhaber F.

Cell Cycle. 2008 Dec;7(23):3709-19. Epub 2008 Dec 13. Erratum in: Cell Cycle. 2009 Feb 1;8(3):508-9.

PMID:
19029837
20.

Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.

Neumüller RA, Betschinger J, Fischer A, Bushati N, Poernbacher I, Mechtler K, Cohen SM, Knoblich JA.

Nature. 2008 Jul 10;454(7201):241-5. doi: 10.1038/nature07014. Epub 2008 Jun 4.

21.

The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division.

Bowman SK, Neumüller RA, Novatchkova M, Du Q, Knoblich JA.

Dev Cell. 2006 Jun;10(6):731-42.

22.

[Pelviscopy under epidural and general anaesthesia. Comparison of two methods].

Schulte-Steinberg O, Neumüller R.

Reg Anaesth. 1982 Jul;5(3):68-72. German.

PMID:
6812173

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