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Items: 47

1.

Prognostic Value of a Novel and Established High-Sensitivity Troponin I Assay in Patients Presenting with Suspected Myocardial Infarction.

Sörensen NA, Ludwig S, Makarova N, Neumann JT, Lehmacher J, Hartikainen TS, Haller PM, Keller T, Blankenberg S, Westermann D, Zeller T, Schofer N.

Biomolecules. 2019 Sep 9;9(9). pii: E469. doi: 10.3390/biom9090469.

2.

Machine Learning to Predict the Likelihood of Acute Myocardial Infarction.

Than MP, Pickering JW, Sandoval Y, Shah ASV, Tsanas A, Apple FS, Blankenberg S, Cullen L, Mueller C, Neumann JT, Twerenbold R, Westermann D, Beshiri A, Mills NL; MI3 collaborative.

Circulation. 2019 Aug 16. doi: 10.1161/CIRCULATIONAHA.119.041980. [Epub ahead of print]

3.

Effect of renal denervation procedure on left ventricular mass, myocardial strain and diastolic function by CMR on a 12-month follow-up.

Tahir E, Koops A, Warncke ML, Starekova J, Neumann JT, Waldeyer C, Avanesov M, Lund GK, Fischer R, Adam G, Blankenberg S, Wenzel UO, Brunner FJ.

Jpn J Radiol. 2019 Sep;37(9):642-650. doi: 10.1007/s11604-019-00854-y. Epub 2019 Jul 12.

PMID:
31301000
4.

Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.

Neumann JT, Twerenbold R, Ojeda F, Sörensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jørgensen T, Söderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renné T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S.

N Engl J Med. 2019 Jun 27;380(26):2529-2540. doi: 10.1056/NEJMoa1803377.

PMID:
31242362
5.

Comparative Analysis of Circulating Noncoding RNAs Versus Protein Biomarkers in the Detection of Myocardial Injury.

Schulte C, Barwari T, Joshi A, Theofilatos K, Zampetaki A, Barallobre-Barreiro J, Singh B, Sörensen NA, Neumann JT, Zeller T, Westermann D, Blankenberg S, Marber M, Liebetrau C, Mayr M.

Circ Res. 2019 Jul 19;125(3):328-340. doi: 10.1161/CIRCRESAHA.119.314937. Epub 2019 Jun 4.

6.

Predictive value of soluble urokinase-type plasminogen activator receptor for mortality in patients with suspected myocardial infarction.

Sörensen NA, Nikorowitsch J, Neumann JT, Rübsamen N, Goßling A, Hartikainen TS, Blankenberg S, Westermann D, Zeller T, Karakas M.

Clin Res Cardiol. 2019 Apr 16. doi: 10.1007/s00392-019-01475-1. [Epub ahead of print]

PMID:
30989318
7.

Diagnostic Value of Soluble Urokinase-Type Plasminogen Activator Receptor in Addition to High-Sensitivity Troponin I in Early Diagnosis of Acute Myocardial Infarction.

Sörensen NA, Dönmez G, Neumann JT, Nikorowitsch J, Rübsamen N, Blankenberg S, Westermann D, Zeller T, Karakas M.

Biomolecules. 2019 Mar 18;9(3). pii: E108. doi: 10.3390/biom9030108.

8.

More evidence for high-sensitivity troponin assays.

Neumann JT, Westermann D.

Heart. 2019 Apr;105(8):587-588. doi: 10.1136/heartjnl-2018-314280. Epub 2018 Dec 31. No abstract available.

PMID:
30598457
9.

Venoarterial Extracorporeal Membrane Oxygenation for Cardiopulmonary Support.

Becher PM, Schrage B, Sinning CR, Schmack B, Fluschnik N, Schwarzl M, Waldeyer C, Lindner D, Seiffert M, Neumann JT, Bernhardt AM, Zeymer U, Thiele H, Reichenspurner H, Blankenberg S, Twerenbold R, Westermann D.

Circulation. 2018 Nov 13;138(20):2298-2300. doi: 10.1161/CIRCULATIONAHA.118.036691. No abstract available.

PMID:
30571518
10.

Reply: Hospital Charges Associated With Inpatient Troponin Testing.

Twerenbold R, Neumann JT, Blankenberg S, Westermann D, Mueller C.

J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2941. doi: 10.1016/j.jacc.2018.09.054. No abstract available.

PMID:
30522660
11.

Evaluation of a new ultra-sensitivity troponin I assay in patients with suspected myocardial infarction.

Neumann JT, Sörensen NA, Rübsamen N, Ojeda F, Schock A, Seddighizadeh P, Zeller T, Westermann D, Blankenberg S.

Int J Cardiol. 2019 May 15;283:35-40. doi: 10.1016/j.ijcard.2018.12.001. Epub 2018 Dec 5.

PMID:
30528623
12.

Palmitic acid methyl ester is a novel neuroprotective agent against cardiac arrest.

Lee RH, Couto E Silva A, Possoit HE, Lerner FM, Chen PY, Azizbayeva R, Citadin CT, Wu CY, Neumann JT, Lin HW.

Prostaglandins Leukot Essent Fatty Acids. 2019 Aug;147:6-14. doi: 10.1016/j.plefa.2018.11.011. Epub 2018 Nov 23.

PMID:
30514597
13.

Cardiac Troponins for the Diagnosis of Acute Myocardial Infarction in Chronic Kidney Disease.

Kraus D, von Jeinsen B, Tzikas S, Palapies L, Zeller T, Bickel C, Fette G, Lackner KJ, Drechsler C, Neumann JT, Baldus S, Blankenberg S, Münzel T, Wanner C, Zeiher AM, Keller T.

J Am Heart Assoc. 2018 Oct 2;7(19):e008032. doi: 10.1161/JAHA.117.008032.

14.

Right bundle branch block in patients with suspected myocardial infarction.

Neumann JT, Sörensen NA, Rübsamen N, Ojeda F, Schäfer S, Keller T, Blankenberg S, Clemmensen P, Westermann D.

Eur Heart J Acute Cardiovasc Care. 2019 Mar;8(2):161-166. doi: 10.1177/2048872618809700. Epub 2018 Oct 26.

PMID:
30362813
15.

Diagnosing myocardial infarction: a highly sensitive issue.

Blankenberg S, Neumann JT, Westermann D.

Lancet. 2018 Sep 15;392(10151):893-894. doi: 10.1016/S0140-6736(18)31996-2. Epub 2018 Aug 28. No abstract available.

16.

Impact of age on the performance of the ESC 0/1h-algorithms for early diagnosis of myocardial infarction.

Boeddinghaus J, Nestelberger T, Twerenbold R, Neumann JT, Lindahl B, Giannitsis E, Sörensen NA, Badertscher P, Jann JE, Wussler D, Puelacher C, Rubini Giménez M, Wildi K, Strebel I, Du Fay de Lavallaz J, Selman F, Sabti Z, Kozhuharov N, Potlukova E, Rentsch K, Miró Ò, Martin-Sanchez FJ, Morawiec B, Parenica J, Lohrmann J, Kloos W, Buser A, Geigy N, Keller DI, Osswald S, Reichlin T, Westermann D, Blankenberg S, Mueller C; APACE, BACC, and TRAPID-AMI Investigators.

Eur Heart J. 2018 Nov 7;39(42):3780-3794. doi: 10.1093/eurheartj/ehy514.

PMID:
30169752
17.

Precursor proadrenomedullin influences cardiomyocyte survival and local inflammation related to myocardial infarction.

Hinrichs S, Scherschel K, Krüger S, Neumann JT, Schwarzl M, Yan I, Warnke S, Ojeda FM, Zeller T, Karakas M, Keller T, Meyer C, Blankenberg S, Westermann D, Lindner D.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8727-E8736. doi: 10.1073/pnas.1721635115. Epub 2018 Aug 30.

18.

Clinical chemistry score versus high-sensitivity cardiac troponin I and T tests alone to identify patients at low or high risk for myocardial infarction or death at presentation to the emergency department.

Kavsak PA, Neumann JT, Cullen L, Than M, Shortt C, Greenslade JH, Pickering JW, Ojeda F, Ma J, Clayton N, Sherbino J, Hill SA, McQueen M, Westermann D, Sörensen NA, Parsonage WA, Griffith L, Mehta SR, Devereaux PJ, Richards M, Troughton R, Pemberton C, Aldous S, Blankenberg S, Worster A.

CMAJ. 2018 Aug 20;190(33):E974-E984. doi: 10.1503/cmaj.180144.

19.

Prospective Validation of the 0/1-h Algorithm for Early Diagnosis of Myocardial Infarction.

Twerenbold R, Neumann JT, Sörensen NA, Ojeda F, Karakas M, Boeddinghaus J, Nestelberger T, Badertscher P, Rubini Giménez M, Puelacher C, Wildi K, Kozhuharov N, Breitenbuecher D, Biskup E, du Fay de Lavallaz J, Flores D, Wussler D, Miró Ò, Martín Sánchez FJ, Morawiec B, Parenica J, Geigy N, Keller DI, Zeller T, Reichlin T, Blankenberg S, Westermann D, Mueller C.

J Am Coll Cardiol. 2018 Aug 7;72(6):620-632. doi: 10.1016/j.jacc.2018.05.040.

20.

Relations of Sex to Diagnosis and Outcomes in Acute Coronary Syndrome.

Sörensen NA, Neumann JT, Ojeda F, Schäfer S, Magnussen C, Keller T, Lackner KJ, Zeller T, Karakas M, Münzel T, Blankenberg S, Westermann D, Schnabel RB.

J Am Heart Assoc. 2018 Mar 10;7(6). pii: e007297. doi: 10.1161/JAHA.117.007297.

21.

Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest.

Wu CYC, Lerner FM, Couto E Silva A, Possoit HE, Hsieh TH, Neumann JT, Minagar A, Lin HW, Lee RHC.

J Vis Exp. 2018 Jan 5;(131). doi: 10.3791/56694.

22.

Discrimination of patients with type 2 myocardial infarction.

Neumann JT, Sörensen NA, Rübsamen N, Ojeda F, Renné T, Qaderi V, Teltrop E, Kramer S, Quantius L, Zeller T, Karakas M, Blankenberg S, Westermann D.

Eur Heart J. 2017 Dec 14;38(47):3514-3520. doi: 10.1093/eurheartj/ehx457.

PMID:
29020401
23.

Cardiovascular Biomarkers in Hypertensive Patients with Medical Treatment-Results from the Randomized TEAMSTA Protect I Trial.

Jagodzinski A, Neumann JT, Ojeda F, Sörensen NA, Wild P, Münzel T, Zeller T, Westermann D, Blankenberg S.

Clin Chem. 2017 Dec;63(12):1877-1885. doi: 10.1373/clinchem.2017.275289. Epub 2017 Sep 13.

24.

Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure.

Zeller T, Schurmann C, Schramm K, Müller C, Kwon S, Wild PS, Teumer A, Herrington D, Schillert A, Iacoviello L, Kratzer A, Jagodzinski A, Karakas M, Ding J, Neumann JT, Kuulasmaa K, Gieger C, Kacprowski T, Schnabel RB, Roden M, Wahl S, Rotter JI, Ojeda F, Carstensen-Kirberg M, Tregouet DA, Dörr M, Meitinger T, Lackner KJ, Wolf P, Felix SB, Landmesser U, Costanzo S, Ziegler A, Liu Y, Völker U, Palmas W, Prokisch H, Guo X, Herder C, Blankenberg S, Homuth G.

Hypertension. 2017 Oct;70(4):743-750. doi: 10.1161/HYPERTENSIONAHA.117.09458. Epub 2017 Aug 7.

25.

High-sensitivity assays for troponin in patients with cardiac disease.

Westermann D, Neumann JT, Sörensen NA, Blankenberg S.

Nat Rev Cardiol. 2017 Aug;14(8):472-483. doi: 10.1038/nrcardio.2017.48. Epub 2017 Apr 6. Review.

PMID:
28383022
26.

Early diagnosis of acute myocardial infarction using high-sensitivity troponin I.

Neumann JT, Sörensen NA, Ojeda F, Renné T, Schnabel RB, Zeller T, Karakas M, Blankenberg S, Westermann D.

PLoS One. 2017 Mar 23;12(3):e0174288. doi: 10.1371/journal.pone.0174288. eCollection 2017.

27.

Challenging the 99th percentile: A lower troponin cutoff leads to low mortality of chest pain patients.

Sörensen NA, Neumann JT, Ojeda F, Schwemer T, Renné T, Schnabel RB, Zeller T, Karakas M, Blankenberg S, Westermann D.

Int J Cardiol. 2017 Apr 1;232:289-293. doi: 10.1016/j.ijcard.2016.12.167. Epub 2016 Dec 27.

PMID:
28087181
28.

Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I.

Neumann JT, Sörensen NA, Ojeda F, Schwemer T, Lehmacher J, Gönner S, Jarsetz N, Keller T, Schaefer S, Renné T, Landmesser U, Clemmensen P, Makarova N, Schnabel RB, Zeller T, Karakas M, Pickering JW, Than M, Parsonage W, Greenslade J, Cullen L, Westermann D, Blankenberg S.

Clin Chem. 2017 Jan;63(1):394-402. doi: 10.1373/clinchem.2016.262659. Epub 2016 Nov 30.

29.

Interruption of perivascular sympathetic nerves of cerebral arteries offers neuroprotection against ischemia.

Lee RH, Couto E Silva A, Lerner FM, Wilkins CS, Valido SE, Klein DD, Wu CY, Neumann JT, Della-Morte D, Koslow SH, Minagar A, Lin HW.

Am J Physiol Heart Circ Physiol. 2017 Jan 1;312(1):H182-H188. doi: 10.1152/ajpheart.00482.2016. Epub 2016 Nov 18.

30.

Diagnosis of Myocardial Infarction Using a High-Sensitivity Troponin I 1-Hour Algorithm.

Neumann JT, Sörensen NA, Schwemer T, Ojeda F, Bourry R, Sciacca V, Schaefer S, Waldeyer C, Sinning C, Renné T, Than M, Parsonage W, Wildi K, Makarova N, Schnabel RB, Landmesser U, Mueller C, Cullen L, Greenslade J, Zeller T, Blankenberg S, Karakas M, Westermann D.

JAMA Cardiol. 2016 Jul 1;1(4):397-404. doi: 10.1001/jamacardio.2016.0695.

PMID:
27438315
31.

Effects of renal denervation on heart failure biomarkers and blood pressure in patients with resistant hypertension.

Neumann JT, Ewen S, Mortensen K, Nef H, Zeller T, Ojeda F, Sydow K, Mahfoud F, Böhm M, Hamm C, Dörr O, Blankenberg S.

Biomark Med. 2016 Aug;10(8):841-51. doi: 10.2217/bmm-2016-0098.

PMID:
27428075
32.

Be more sensitive, please - using cardiac troponin assays for diagnosing AMI.

Neumann JT, Blankenberg S, Westermann D.

Heart. 2016 Aug 15;102(16):1251-2. doi: 10.1136/heartjnl-2016-309484. Epub 2016 Jun 20. No abstract available.

PMID:
27325589
33.

Biomarker response and therapy prediction in renal denervation therapy - the role of MR-proadrenomedullin in a multicenter approach.

Neumann JT, Schwerg M, Dörr O, Mortensen K, Franzen K, Zeller T, Ojeda F, Blankenberg S, Hamm C, Nef H, Stangl V, Möckel M, Sydow K.

Biomarkers. 2017 May - Jun;22(3-4):225-231. doi: 10.3109/1354750X.2016.1172112. Epub 2016 May 6.

PMID:
27153479
34.

Biomarkers in the triage of chest pain: are we making progress?

Neumann JT, Sörensen NA, Westermann D.

Biomark Med. 2016;10(4):345-7. doi: 10.2217/bmm.16.7. Epub 2016 Mar 22. No abstract available.

35.

Resveratrol Preconditioning Induces a Novel Extended Window of Ischemic Tolerance in the Mouse Brain.

Koronowski KB, Dave KR, Saul I, Camarena V, Thompson JW, Neumann JT, Young JI, Perez-Pinzon MA.

Stroke. 2015 Aug;46(8):2293-8. doi: 10.1161/STROKEAHA.115.009876. Epub 2015 Jul 9.

36.

Effect of cardiac arrest on cognitive impairment and hippocampal plasticity in middle-aged rats.

Cohan CH, Neumann JT, Dave KR, Alekseyenko A, Binkert M, Stransky K, Lin HW, Barnes CA, Wright CB, Perez-Pinzon MA.

PLoS One. 2015 May 1;10(5):e0124918. doi: 10.1371/journal.pone.0124918. eCollection 2015.

37.

Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection.

Neumann JT, Thompson JW, Raval AP, Cohan CH, Koronowski KB, Perez-Pinzon MA.

J Cereb Blood Flow Metab. 2015 Jan;35(1):121-30. doi: 10.1038/jcbfm.2014.185. Epub 2014 Nov 5.

38.

Protein kinase C epsilon regulates mitochondrial pools of Nampt and NAD following resveratrol and ischemic preconditioning in the rat cortex.

Morris-Blanco KC, Cohan CH, Neumann JT, Sick TJ, Perez-Pinzon MA.

J Cereb Blood Flow Metab. 2014 Jun;34(6):1024-32. doi: 10.1038/jcbfm.2014.51. Epub 2014 Mar 26.

39.

Comparison of three troponins as predictors of future cardiovascular events--prospective results from the FINRISK and BiomaCaRE studies.

Neumann JT, Havulinna AS, Zeller T, Appelbaum S, Kunnas T, Nikkari S, Jousilahti P, Blankenberg S, Sydow K, Salomaa V.

PLoS One. 2014 Mar 4;9(3):e90063. doi: 10.1371/journal.pone.0090063. eCollection 2014.

40.

Protein kinase C delta modulates endothelial nitric oxide synthase after cardiac arrest.

Lin HW, Gresia VL, Stradecki HM, Alekseyenko A, Dezfulian C, Neumann JT, Dave KR, Perez-Pinzon MA.

J Cereb Blood Flow Metab. 2014 Apr;34(4):613-20. doi: 10.1038/jcbfm.2013.232. Epub 2014 Jan 22.

41.

Fatty acid methyl esters and Solutol HS 15 confer neuroprotection after focal and global cerebral ischemia.

Lin HW, Saul I, Gresia VL, Neumann JT, Dave KR, Perez-Pinzon MA.

Transl Stroke Res. 2014 Feb;5(1):109-17. doi: 10.1007/s12975-013-0276-z. Epub 2013 Aug 6.

42.

Neutrophils amplify autoimmune central nervous system infiltrates by maturing local APCs.

Steinbach K, Piedavent M, Bauer S, Neumann JT, Friese MA.

J Immunol. 2013 Nov 1;191(9):4531-9. doi: 10.4049/jimmunol.1202613. Epub 2013 Sep 23.

43.

Association of MR-proadrenomedullin with cardiovascular risk factors and subclinical cardiovascular disease.

Neumann JT, Tzikas S, Funke-Kaiser A, Wilde S, Appelbaum S, Keller T, Ojeda-Echevarria F, Zeller T, Zwiener I, Sinning CR, Jagodzinski A, Schnabel RB, Lackner KJ, Münzel T, Blankenberg S, Wild PS, Sydow K.

Atherosclerosis. 2013 Jun;228(2):451-9. doi: 10.1016/j.atherosclerosis.2013.03.006. Epub 2013 Mar 19.

PMID:
23562132
44.

Global cerebral ischemia: synaptic and cognitive dysfunction.

Neumann JT, Cohan CH, Dave KR, Wright CB, Perez-Pinzon MA.

Curr Drug Targets. 2013 Jan 1;14(1):20-35. Review.

45.

Coupled gating of skeletal muscle ryanodine receptors is modulated by Ca2+, Mg2+, and ATP.

Porta M, Diaz-Sylvester PL, Neumann JT, Escobar AL, Fleischer S, Copello JA.

Am J Physiol Cell Physiol. 2012 Sep 15;303(6):C682-97. doi: 10.1152/ajpcell.00150.2012. Epub 2012 Jul 11.

46.

Cross-reactivity of ryanodine receptors with plasma membrane ion channel modulators.

Neumann JT, Copello JA.

Mol Pharmacol. 2011 Sep;80(3):509-17. doi: 10.1124/mol.111.071167. Epub 2011 Jun 10.

47.

CGP-37157 inhibits the sarcoplasmic reticulum Ca²+ ATPase and activates ryanodine receptor channels in striated muscle.

Neumann JT, Diaz-Sylvester PL, Fleischer S, Copello JA.

Mol Pharmacol. 2011 Jan;79(1):141-7. doi: 10.1124/mol.110.067165. Epub 2010 Oct 5.

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