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Items: 29


Targeted in-vitro-stimulation reveals highly proliferative multi-virus-specific human central memory T cells as candidates for prophylactic T cell therapy.

Faist B, Schlott F, Stemberger C, Dennehy KM, Krackhardt A, Verbeek M, Grigoleit GU, Schiemann M, Hoffmann D, Dick A, Martin K, Hildebrandt M, Busch DH, Neuenhahn M.

PLoS One. 2019 Sep 30;14(9):e0223258. doi: 10.1371/journal.pone.0223258. eCollection 2019.


Characterization and clinical enrichment of HLA-C*07:02-restricted Cytomegalovirus-specific CD8+ T cells.

Schlott F, Steubl D, Ameres S, Moosmann A, Dreher S, Heemann U, Hösel V, Busch DH, Neuenhahn M.

PLoS One. 2018 Feb 28;13(2):e0193554. doi: 10.1371/journal.pone.0193554. eCollection 2018.


Primary Cytomegalovirus Infection in Seronegative Kidney Transplant Patients Is Associated with Protracted Cold Ischemic Time of Seropositive Donor Organs.

Schlott F, Steubl D, Hoffmann D, Matevossian E, Lutz J, Heemann U, Hösel V, Busch DH, Renders L, Neuenhahn M.

PLoS One. 2017 Jan 27;12(1):e0171035. doi: 10.1371/journal.pone.0171035. eCollection 2017.


Transfer of minimally manipulated CMV-specific T cells from stem cell or third-party donors to treat CMV infection after allo-HSCT.

Neuenhahn M, Albrecht J, Odendahl M, Schlott F, Dössinger G, Schiemann M, Lakshmipathi S, Martin K, Bunjes D, Harsdorf S, Weissinger EM, Menzel H, Verbeek M, Uharek L, Kröger N, Wagner E, Kobbe G, Schroeder T, Schmitt M, Held G, Herr W, Germeroth L, Bonig H, Tonn T, Einsele H, Busch DH, Grigoleit GU.

Leukemia. 2017 Oct;31(10):2161-2171. doi: 10.1038/leu.2017.16. Epub 2017 Jan 16.


Presentation of a Conserved Adenoviral Epitope on HLA-C*0702 Allows Evasion of Natural Killer but Not T Cell Responses.

Keib A, Günther PS, Faist B, Halenius A, Busch DH, Neuenhahn M, Jahn G, Dennehy KM.

Viral Immunol. 2017 Apr;30(3):149-156. doi: 10.1089/vim.2016.0145. Epub 2017 Jan 13.


Comparison of 1,3-β-d-glucan with galactomannan in serum and bronchoalveolar fluid for the detection of Aspergillus species in immunosuppressed mechanical ventilated critically ill patients.

Lahmer T, Neuenhahn M, Held J, Rasch S, Schmid RM, Huber W.

J Crit Care. 2016 Dec;36:259-264. doi: 10.1016/j.jcrc.2016.06.026. Epub 2016 Jul 9.


Identification of a Novel Immunodominant HLA-B*07: 02-restricted Adenoviral Peptide Epitope and Its Potential in Adoptive Transfer Immunotherapy.

Günther PS, Peper JK, Faist B, Kayser S, Hartl L, Feuchtinger T, Jahn G, Neuenhahn M, Busch DH, Stevanović S, Dennehy KM.

J Immunother. 2015 Sep;38(7):267-75. doi: 10.1097/CJI.0000000000000087.


Clinical-scale isolation of 'minimally manipulated' cytomegalovirus-specific donor lymphocytes for the treatment of refractory cytomegalovirus disease.

Odendahl M, Grigoleit GU, Bönig H, Neuenhahn M, Albrecht J, Anderl F, Germeroth L, Schmitz M, Bornhäuser M, Einsele H, Seifried E, Busch DH, Tonn T.

Cytotherapy. 2014 Sep;16(9):1245-56. doi: 10.1016/j.jcyt.2014.05.023.


Lowest numbers of primary CD8(+) T cells can reconstitute protective immunity upon adoptive immunotherapy.

Stemberger C, Graef P, Odendahl M, Albrecht J, Dössinger G, Anderl F, Buchholz VR, Gasteiger G, Schiemann M, Grigoleit GU, Schuster FR, Borkhardt A, Versluys B, Tonn T, Seifried E, Einsele H, Germeroth L, Busch DH, Neuenhahn M.

Blood. 2014 Jul 24;124(4):628-37. doi: 10.1182/blood-2013-12-547349. Epub 2014 May 22.


Overnight resting of PBMC changes functional signatures of antigen specific T- cell responses: impact for immune monitoring within clinical trials.

Kutscher S, Dembek CJ, Deckert S, Russo C, Körber N, Bogner JR, Geisler F, Umgelter A, Neuenhahn M, Albrecht J, Cosma A, Protzer U, Bauer T.

PLoS One. 2013 Oct 11;8(10):e76215. doi: 10.1371/journal.pone.0076215. eCollection 2013.


Acute hypophysitis and hypopituitarism in early syphilitic meningitis in a HIV-infected patient: a case report.

Spinner CD, Noe S, Schwerdtfeger C, Todorova A, Gaa J, Schmid RM, Busch DH, Neuenhahn M.

BMC Infect Dis. 2013 Oct 17;13:481. doi: 10.1186/1471-2334-13-481.


TCR-ligand koff rate correlates with the protective capacity of antigen-specific CD8+ T cells for adoptive transfer.

Nauerth M, Weißbrich B, Knall R, Franz T, Dössinger G, Bet J, Paszkiewicz PJ, Pfeifer L, Bunse M, Uckert W, Holtappels R, Gillert-Marien D, Neuenhahn M, Krackhardt A, Reddehase MJ, Riddell SR, Busch DH.

Sci Transl Med. 2013 Jul 3;5(192):192ra87. doi: 10.1126/scitranslmed.3005958.


Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion.

Ameres S, Mautner J, Schlott F, Neuenhahn M, Busch DH, Plachter B, Moosmann A.

PLoS Pathog. 2013;9(5):e1003383. doi: 10.1371/journal.ppat.1003383. Epub 2013 May 23.


MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy.

Dössinger G, Bunse M, Bet J, Albrecht J, Paszkiewicz PJ, Weißbrich B, Schiedewitz I, Henkel L, Schiemann M, Neuenhahn M, Uckert W, Busch DH.

PLoS One. 2013 Apr 26;8(4):e61384. doi: 10.1371/journal.pone.0061384. Print 2013.


Whole-body anatomy of human T cells.

Neuenhahn M, Busch DH.

Immunity. 2013 Jan 24;38(1):10-2. doi: 10.1016/j.immuni.2013.01.006.


Novel serial positive enrichment technology enables clinical multiparameter cell sorting.

Stemberger C, Dreher S, Tschulik C, Piossek C, Bet J, Yamamoto TN, Schiemann M, Neuenhahn M, Martin K, Schlapschy M, Skerra A, Schmidt T, Edinger M, Riddell SR, Germeroth L, Busch DH.

PLoS One. 2012;7(4):e35798. doi: 10.1371/journal.pone.0035798. Epub 2012 Apr 24.


A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3.

Verschoor A, Neuenhahn M, Navarini AA, Graef P, Plaumann A, Seidlmeier A, Nieswandt B, Massberg S, Zinkernagel RM, Hengartner H, Busch DH.

Nat Immunol. 2011 Oct 30;12(12):1194-201. doi: 10.1038/ni.2140.


CD8+ T cell differentiation in the aging immune system: until the last clone standing.

Buchholz VR, Neuenhahn M, Busch DH.

Curr Opin Immunol. 2011 Aug;23(4):549-54. doi: 10.1016/j.coi.2011.05.002. Epub 2011 Jun 12. Review.


DCs in mouse models of intracellular bacterial infection.

Neuenhahn M, Schiemann M, Busch DH.

Methods Mol Biol. 2010;595:319-29. doi: 10.1007/978-1-60761-421-0_21.


The quest for CD8+ memory stem cells.

Neuenhahn M, Busch DH.

Immunity. 2009 Nov 20;31(5):702-4. doi: 10.1016/j.immuni.2009.10.002.


Stem cell-like plasticity of naïve and distinct memory CD8+ T cell subsets.

Stemberger C, Neuenhahn M, Gebhardt FE, Schiemann M, Buchholz VR, Busch DH.

Semin Immunol. 2009 Apr;21(2):62-8. doi: 10.1016/j.smim.2009.02.004. Epub 2009 Mar 9. Review.


5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.

Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya SS, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Häcker G, Neuenhahn M, Busch D, Ruland J, Rothenfusser S, Prinz M, Hornung V, Endres S, Tüting T, Hartmann G.

Nat Med. 2008 Nov;14(11):1256-63. doi: 10.1038/nm.1887. Epub 2008 Nov 2.


Decreased susceptibility of mice to infection with Listeria monocytogenes in the absence of interleukin-18.

Lochner M, Kastenmüller K, Neuenhahn M, Weighardt H, Busch DH, Reindl W, Förster I.

Infect Immun. 2008 Sep;76(9):3881-90. doi: 10.1128/IAI.01651-07. Epub 2008 Jun 23.


Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cell-mediated immunity.

Heit A, Gebhardt F, Lahl K, Neuenhahn M, Schmitz F, Anderl F, Wagner H, Sparwasser T, Busch DH, Kastenmüller K.

Eur J Immunol. 2008 Jun;38(6):1585-97. doi: 10.1002/eji.200737966.


Origin of CD8+ effector and memory T cell subsets.

Stemberger C, Neuenhahn M, Buchholz VR, Busch DH.

Cell Mol Immunol. 2007 Dec;4(6):399-405. Review.


Unique functions of splenic CD8alpha+ dendritic cells during infection with intracellular pathogens.

Neuenhahn M, Busch DH.

Immunol Lett. 2007 Dec 15;114(2):66-72. Epub 2007 Oct 12. Review.


NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

Greten FR, Arkan MC, Bollrath J, Hsu LC, Goode J, Miething C, Göktuna SI, Neuenhahn M, Fierer J, Paxian S, Van Rooijen N, Xu Y, O'Cain T, Jaffee BB, Busch DH, Duyster J, Schmid RM, Eckmann L, Karin M.

Cell. 2007 Sep 7;130(5):918-31.


CD8alpha+ dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen.

Neuenhahn M, Kerksiek KM, Nauerth M, Suhre MH, Schiemann M, Gebhardt FE, Stemberger C, Panthel K, Schröder S, Chakraborty T, Jung S, Hochrein H, Rüssmann H, Brocker T, Busch DH.

Immunity. 2006 Oct;25(4):619-30. Epub 2006 Oct 5.


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