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Items: 1 to 50 of 81

1.

Microbial synthesis of the type I polyketide 6-methylsalicylate with Corynebacterium glutamicum.

Kallscheuer N, Kage H, Milke L, Nett M, Marienhagen J.

Appl Microbiol Biotechnol. 2019 Dec;103(23-24):9619-9631. doi: 10.1007/s00253-019-10121-9. Epub 2019 Nov 4.

PMID:
31686146
2.

Myxochelin- and Pseudochelin-Derived Lipoxygenase Inhibitors from a Genetically Engineered Myxococcus xanthus Strain.

Sester A, Winand L, Pace S, Hiller W, Werz O, Nett M.

J Nat Prod. 2019 Sep 27;82(9):2544-2549. doi: 10.1021/acs.jnatprod.9b00403. Epub 2019 Aug 29.

PMID:
31465225
3.

Genomics-inspired discovery of massiliachelin, an agrochelin epimer from Massilia sp. NR 4-1.

Diettrich J, Kage H, Nett M.

Beilstein J Org Chem. 2019 Jun 13;15:1298-1303. doi: 10.3762/bjoc.15.128. eCollection 2019.

4.

Cross-Chemistry Leads to Product Diversity from Atromentin Synthetases in Aspergilli from Section Nigri.

Geib E, Baldeweg F, Doerfer M, Nett M, Brock M.

Cell Chem Biol. 2019 Feb 21;26(2):223-234.e6. doi: 10.1016/j.chembiol.2018.10.021. Epub 2018 Dec 6.

PMID:
30527997
5.

Algae induce siderophore biosynthesis in the freshwater bacterium Cupriavidus necator H16.

Kurth C, Wasmuth I, Wichard T, Pohnert G, Nett M.

Biometals. 2019 Feb;32(1):77-88. doi: 10.1007/s10534-018-0159-6. Epub 2018 Nov 24.

PMID:
30474772
6.

Engineering Pseudochelin Production in Myxococcus xanthus.

Korp J, Winand L, Sester A, Nett M.

Appl Environ Microbiol. 2018 Oct 30;84(22). pii: e01789-18. doi: 10.1128/AEM.01789-18. Print 2018 Nov 15.

7.

A genomics perspective on natural product biosynthesis in plant pathogenic bacteria.

Baldeweg F, Hoffmeister D, Nett M.

Nat Prod Rep. 2019 Feb 20;36(2):307-325. doi: 10.1039/c8np00025e. Review.

PMID:
30063232
8.

Herpetopanone, a diterpene from Herpetosiphon aurantiacus discovered by isotope labeling.

Pan X, Domin N, Schieferdecker S, Kage H, Roth M, Nett M.

Beilstein J Org Chem. 2017 Nov 17;13:2458-2465. doi: 10.3762/bjoc.13.242. eCollection 2017.

9.

Structure of Ralsolamycin, the Interkingdom Morphogen from the Crop Plant Pathogen Ralstonia solanacearum.

Baldeweg F, Kage H, Schieferdecker S, Allen C, Hoffmeister D, Nett M.

Org Lett. 2017 Sep 15;19(18):4868-4871. doi: 10.1021/acs.orglett.7b02329. Epub 2017 Aug 28.

PMID:
28846435
10.

Herpetosiphon gulosus sp. nov., a filamentous predatory bacterium isolated from sandy soil and Herpetosiphon giganteus sp. nov., nom. rev.

Pan X, Kage H, Martin K, Nett M.

Int J Syst Evol Microbiol. 2017 Jul;67(7):2476-2481. doi: 10.1099/ijsem.0.002141. Epub 2017 Jul 26.

PMID:
28741992
11.

Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase.

Brandt P, García-Altares M, Nett M, Hertweck C, Hoffmeister D.

Angew Chem Int Ed Engl. 2017 May 15;56(21):5937-5941. doi: 10.1002/anie.201700767. Epub 2017 Apr 25.

PMID:
28440038
12.

Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus.

Valiante V, Mattern DJ, Schüffler A, Horn F, Walther G, Scherlach K, Petzke L, Dickhaut J, Guthke R, Hertweck C, Nett M, Thines E, Brakhage AA.

ACS Chem Biol. 2017 May 19;12(5):1227-1234. doi: 10.1021/acschembio.7b00003. Epub 2017 Mar 15.

PMID:
28233494
13.

A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis.

Braga D, Hoffmeister D, Nett M.

Beilstein J Org Chem. 2016 Dec 16;12:2766-2770. doi: 10.3762/bjoc.12.274. eCollection 2016.

14.

Zincophorin - biosynthesis in Streptomyces griseus and antibiotic properties.

Walther E, Boldt S, Kage H, Lauterbach T, Martin K, Roth M, Hertweck C, Sauerbrei A, Schmidtke M, Nett M.

GMS Infect Dis. 2016 Nov 28;4:Doc08. doi: 10.3205/id000026. eCollection 2016.

15.

Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation.

Schieferdecker S, König S, Pace S, Werz O, Nett M.

ChemMedChem. 2017 Jan 5;12(1):23-27. doi: 10.1002/cmdc.201600536. Epub 2016 Nov 29.

PMID:
27875023
16.

Unraveling the predator-prey relationship of Cupriavidus necator and Bacillus subtilis.

Seccareccia I, Kovács ÁT, Gallegos-Monterrosa R, Nett M.

Microbiol Res. 2016 Nov;192:231-238. doi: 10.1016/j.micres.2016.07.007. Epub 2016 Aug 3.

17.

Siderophores as molecular tools in medical and environmental applications.

Kurth C, Kage H, Nett M.

Org Biomol Chem. 2016 Sep 21;14(35):8212-27. doi: 10.1039/c6ob01400c. Epub 2016 Aug 5. Review.

PMID:
27492756
18.

An Iterative O-Methyltransferase Catalyzes 1,11-Dimethylation of Aspergillus fumigatus Fumaric Acid Amides.

Kalb D, Heinekamp T, Schieferdecker S, Nett M, Brakhage AA, Hoffmeister D.

Chembiochem. 2016 Oct 4;17(19):1813-1817. doi: 10.1002/cbic.201600293. Epub 2016 Aug 18.

PMID:
27442960
19.

Antibiotics from predatory bacteria.

Korp J, Vela Gurovic MS, Nett M.

Beilstein J Org Chem. 2016 Mar 30;12:594-607. doi: 10.3762/bjoc.12.58. eCollection 2016. Review.

20.

The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo.

Schaible AM, Filosa R, Krauth V, Temml V, Pace S, Garscha U, Liening S, Weinigel C, Rummler S, Schieferdecker S, Nett M, Peduto A, Collarile S, Scuotto M, Roviezzo F, Spaziano G, de Rosa M, Stuppner H, Schuster D, D'Agostino B, Werz O.

Biochem Pharmacol. 2016 Jul 15;112:60-71. doi: 10.1016/j.bcp.2016.04.019. Epub 2016 May 5.

PMID:
27157409
21.

Unexpected Metabolic Versatility in a Combined Fungal Fomannoxin/Vibralactone Biosynthesis.

Schwenk D, Brandt P, Blanchette RA, Nett M, Hoffmeister D.

J Nat Prod. 2016 May 27;79(5):1407-14. doi: 10.1021/acs.jnatprod.6b00147. Epub 2016 Apr 22.

PMID:
27104866
22.

Variochelins, Lipopeptide Siderophores from Variovorax boronicumulans Discovered by Genome Mining.

Kurth C, Schieferdecker S, Athanasopoulou K, Seccareccia I, Nett M.

J Nat Prod. 2016 Apr 22;79(4):865-72. doi: 10.1021/acs.jnatprod.5b00932. Epub 2016 Mar 29.

PMID:
27023373
23.

Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase.

Kage H, Riva E, Parascandolo JS, Kreutzer MF, Tosin M, Nett M.

Org Biomol Chem. 2015 Dec 21;13(47):11414-7. doi: 10.1039/c5ob02009c. Epub 2015 Oct 28.

PMID:
26507693
24.

Biosynthetic Origin of the Antibiotic Pseudopyronines A and B in Pseudomonas putida BW11M1.

Bauer JS, Ghequire MG, Nett M, Josten M, Sahl HG, De Mot R, Gross H.

Chembiochem. 2015 Nov;16(17):2491-7. doi: 10.1002/cbic.201500413. Epub 2015 Oct 28.

PMID:
26507104
25.

Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors.

Korp J, König S, Schieferdecker S, Dahse HM, König GM, Werz O, Nett M.

Chembiochem. 2015 Nov;16(17):2445-50. doi: 10.1002/cbic.201500446. Epub 2015 Oct 13.

PMID:
26416255
26.

Rank-Based Similarity Search: Reducing the Dimensional Dependence.

Houle ME, Nett M.

IEEE Trans Pattern Anal Mach Intell. 2015 Jan;37(1):136-50. doi: 10.1109/TPAMI.2014.2343223.

PMID:
26353214
27.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

28.

Quantitative Analysis of Lysobacter Predation.

Seccareccia I, Kost C, Nett M.

Appl Environ Microbiol. 2015 Oct;81(20):7098-105. doi: 10.1128/AEM.01781-15. Epub 2015 Jul 31.

29.

Dandamycin and chandrananimycin E, benzoxazines from Streptomyces griseus.

Barnes EC, Bezerra-Gomes P, Nett M, Hertweck C.

J Antibiot (Tokyo). 2015 Jul;68(7):463-8. doi: 10.1038/ja.2015.10. Epub 2015 Feb 18.

PMID:
25690358
30.

Myxochelins target human 5-lipoxygenase.

Schieferdecker S, König S, Koeberle A, Dahse HM, Werz O, Nett M.

J Nat Prod. 2015 Feb 27;78(2):335-8. doi: 10.1021/np500909b. Epub 2015 Feb 16.

PMID:
25686392
31.

Injury-induced biosynthesis of methyl-branched polyene pigments in a white-rotting basidiomycete.

Schwenk D, Nett M, Dahse HM, Horn U, Blanchette RA, Hoffmeister D.

J Nat Prod. 2014 Dec 26;77(12):2658-63. doi: 10.1021/np500552a. Epub 2014 Nov 24.

PMID:
25420175
32.

Genome mining: concept and strategies for natural product discovery.

Nett M.

Prog Chem Org Nat Prod. 2014;99:199-245. Review. No abstract available.

PMID:
25296440
33.

Structure and biosynthetic assembly of gulmirecins, macrolide antibiotics from the predatory bacterium Pyxidicoccus fallax.

Schieferdecker S, König S, Weigel C, Dahse HM, Werz O, Nett M.

Chemistry. 2014 Nov 24;20(48):15933-40. doi: 10.1002/chem.201404291. Epub 2014 Oct 6.

PMID:
25287056
34.

Ralfuranone Is Produced by an Alternative Aryl-Substituted γ-Lactone Biosynthetic Route in Ralstonia solanacearum.

Pauly J, Nett M, Hoffmeister D.

J Nat Prod. 2014 Aug 22;77(8):1967-71. doi: 10.1021/np500263r.

PMID:
25033087
35.

New myxothiazols from the predatory bacterium Myxococcus fulvus.

Schieferdecker S, Exner TE, Gross H, Roth M, Nett M.

J Antibiot (Tokyo). 2014 Jul;67(7):519-25. doi: 10.1038/ja.2014.31. Epub 2014 Apr 2.

PMID:
24690915
36.

Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA.

Otzen C, Bardl B, Jacobsen ID, Nett M, Brock M.

J Biol Chem. 2014 Mar 21;289(12):8151-69. doi: 10.1074/jbc.M113.517672. Epub 2014 Feb 4.

37.

Precursor-directed biosynthesis of micacocidin derivatives with activity against Mycoplasma pneumoniae.

Kreutzer MF, Kage H, Herrmann J, Pauly J, Hermenau R, Müller R, Hoffmeister D, Nett M.

Org Biomol Chem. 2014 Jan 7;12(1):113-8. doi: 10.1039/c3ob41839a. Epub 2013 Nov 8.

PMID:
24202877
38.

Ralfuranone thioether production by the plant pathogen Ralstonia solanacearum.

Pauly J, Spiteller D, Linz J, Jacobs J, Allen C, Nett M, Hoffmeister D.

Chembiochem. 2013 Nov 4;14(16):2169-78. doi: 10.1002/cbic.201300364. Epub 2013 Sep 17.

PMID:
24106142
39.

An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin.

Kage H, Kreutzer MF, Wackler B, Hoffmeister D, Nett M.

Chem Biol. 2013 Jun 20;20(6):764-71. doi: 10.1016/j.chembiol.2013.04.010.

40.

Micromonospora schwarzwaldensis sp. nov., a producer of telomycin, isolated from soil.

Vela Gurovic MS, Müller S, Domin N, Seccareccia I, Nietzsche S, Martin K, Nett M.

Int J Syst Evol Microbiol. 2013 Oct;63(Pt 10):3812-7. doi: 10.1099/ijs.0.051623-0. Epub 2013 May 10.

PMID:
23667141
41.

Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica.

Kersten RD, Lane AL, Nett M, Richter TK, Duggan BM, Dorrestein PC, Moore BS.

Chembiochem. 2013 May 27;14(8):955-62. doi: 10.1002/cbic.201300147. Epub 2013 May 3.

42.

A gene cluster responsible for biosynthesis of phomenoic acid in the plant pathogenic fungus, Leptosphaeria maculans.

Elliott CE, Callahan DL, Schwenk D, Nett M, Hoffmeister D, Howlett BJ.

Fungal Genet Biol. 2013 Apr;53:50-8. doi: 10.1016/j.fgb.2013.01.008. Epub 2013 Feb 7.

PMID:
23396262
43.

Blood loss and transfusion rates following patellofemoral arthroplasty.

Courtney J, Liebelt D, Nett MP, Cushner FD.

Orthop Clin North Am. 2012 Nov;43(5):e44-7. doi: 10.1016/j.ocl.2012.07.007. Epub 2012 Sep 25. Review.

PMID:
23102421
44.

Genomics-driven discovery of taiwachelin, a lipopeptide siderophore from Cupriavidus taiwanensis.

Kreutzer MF, Nett M.

Org Biomol Chem. 2012 Dec 21;10(47):9338-43. doi: 10.1039/c2ob26296g. Epub 2012 Sep 12.

PMID:
22972004
45.

Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)).

Kiss H, Nett M, Domin N, Martin K, Maresca JA, Copeland A, Lapidus A, Lucas S, Berry KW, Glavina Del Rio T, Dalin E, Tice H, Pitluck S, Richardson P, Bruce D, Goodwin L, Han C, Detter JC, Schmutz J, Brettin T, Land M, Hauser L, Kyrpides NC, Ivanova N, Göker M, Woyke T, Klenk HP, Bryant DA.

Stand Genomic Sci. 2011 Dec 31;5(3):356-70. doi: 10.4056/sigs.2194987. Epub 2011 Dec 23.

46.

Structure and biosynthetic assembly of cupriachelin, a photoreactive siderophore from the bioplastic producer Cupriavidus necator H16.

Kreutzer MF, Kage H, Nett M.

J Am Chem Soc. 2012 Mar 21;134(11):5415-22. doi: 10.1021/ja300620z. Epub 2012 Mar 13.

PMID:
22381697
47.

4-Hydroxyphenylglycine biosynthesis in Herpetosiphon aurantiacus: a case of gene duplication and catalytic divergence.

Kastner S, Müller S, Natesan L, König GM, Guthke R, Nett M.

Arch Microbiol. 2012 Jun;194(6):557-66. doi: 10.1007/s00203-012-0789-y. Epub 2012 Feb 4.

PMID:
22307823
48.

Farinamycin, a quinazoline from Streptomyces griseus.

Nett M, Hertweck C.

J Nat Prod. 2011 Oct 28;74(10):2265-8. doi: 10.1021/np2002513. Epub 2011 Sep 22.

PMID:
21939253
49.

Biosynthesis of a complex yersiniabactin-like natural product via the mic locus in phytopathogen Ralstonia solanacearum.

Kreutzer MF, Kage H, Gebhardt P, Wackler B, Saluz HP, Hoffmeister D, Nett M.

Appl Environ Microbiol. 2011 Sep;77(17):6117-24. doi: 10.1128/AEM.05198-11. Epub 2011 Jul 1.

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