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Items: 1 to 50 of 800

1.

Predictive value of ex-vivo drug-inhibited cytokine production for clinical response to biologic DMARD therapy in rheumatoid arthritis.

Tweehuysen L, den Broeder AA, Schraa K, Netea MG, van den Hoogen FHJ, Joosten LAB.

Clin Exp Rheumatol. 2019 Feb 7. [Epub ahead of print]

PMID:
30767874
2.

Metformin alters human host responses to Mycobacterium tuberculosis in healthy subjects.

Lachmandas E, Eckold C, Böhme J, Koeken VACM, Marzuki MB, Blok B, Arts RJW, Chen J, Teng KWW, Ratter J, Smolders EJ, van den Heuvel C, Stienstra R, Dockrell HM, Newell E, Netea MG, Singhal A, Cliff JM, van Crevel R.

J Infect Dis. 2019 Feb 12. doi: 10.1093/infdis/jiz064. [Epub ahead of print]

PMID:
30753544
3.

Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression.

Cleophas MCP, Crişan TO, Klück V, Hoogerbrugge N, Netea-Maier RT, Dinarello CA, Netea MG, Joosten LAB.

Arthritis Res Ther. 2019 Feb 6;21(1):50. doi: 10.1186/s13075-019-1834-x.

4.

Opposite effects of Vaccinia and modified Vaccinia Ankara on trained immunity.

Blok BA, Jensen KJ, Aaby P, Fomsgaard A, van Crevel R, Benn CS, Netea MG.

Eur J Clin Microbiol Infect Dis. 2019 Mar;38(3):449-456. doi: 10.1007/s10096-018-03449-z. Epub 2019 Feb 5.

PMID:
30719592
5.

Maternal Priming: Bacillus Calmette-Guérin (BCG) Vaccine Scarring in Mothers Enhances the Survival of Their Child With a BCG Vaccine Scar.

Berendsen MLT, Øland CB, Bles P, Jensen AKG, Kofoed PE, Whittle H, De Bree C, Netea MG, Martins C, Benn CS, Aaby P.

J Pediatric Infect Dis Soc. 2019 Feb 3. doi: 10.1093/jpids/piy142. [Epub ahead of print]

PMID:
30715451
6.

Immune cell characteristics and cytokine responses in adult HIV-negative tuberculous meningitis: an observational cohort study.

van Laarhoven A, Dian S, van Dorp S, Purnama F, Koeken VACM, Diandini E, Utami F, Livia R, Apriani L, Ardiansyah E, Ter Horst R, Netea MG, Achmad TH, Hill PC, Ruslami R, Alisjahbana B, Ussher JE, Indrati A, Verrall A, Ganiem AR, van Crevel R.

Sci Rep. 2019 Jan 29;9(1):884. doi: 10.1038/s41598-018-36696-3.

7.

Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males.

Cleophas MCP, Ratter JM, Bekkering S, Quintin J, Schraa K, Stroes ES, Netea MG, Joosten LAB.

Sci Rep. 2019 Jan 28;9(1):775. doi: 10.1038/s41598-018-37246-7.

8.

Cytokine profiles in patients with Q fever fatigue syndrome.

Raijmakers RPH, Koeken VACM, Jansen AFM, Keijmel SP, Roerink ME, Joosten LAB, Netea MG, van der Meer JWM, Bleeker-Rovers CP.

J Infect. 2019 Jan 23. pii: S0163-4453(19)30027-1. doi: 10.1016/j.jinf.2019.01.006. [Epub ahead of print]

PMID:
30684502
9.

Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome.

Sloot YJE, Rabold K, Netea MG, Smit JWA, Hoogerbrugge N, Netea-Maier RT.

Oncogene. 2019 Jan 22. doi: 10.1038/s41388-019-0685-x. [Epub ahead of print]

PMID:
30670777
10.

The fecal and mucosal microbiome in acute appendicitis patients: an observational study.

Peeters T, Penders J, Smeekens SP, Galazzo G, Houben B, Netea MG, Savelkoul PH, Gyssens IC.

Future Microbiol. 2019 Jan 21. doi: 10.2217/fmb-2018-0203. [Epub ahead of print]

PMID:
30663346
11.

Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens.

Netea MG, Schlitzer A, Placek K, Joosten LAB, Schultze JL.

Cell Host Microbe. 2019 Jan 9;25(1):13-26. doi: 10.1016/j.chom.2018.12.006. Review.

PMID:
30629914
12.

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations.

Sánchez-Ramón S, Conejero L, Netea MG, Sancho D, Palomares Ó, Subiza JL.

Front Immunol. 2018 Dec 17;9:2936. doi: 10.3389/fimmu.2018.02936. eCollection 2018. Review.

13.

Genetic variations in innate immunity genes affect response to Coxiella burnetii and are associated with susceptibility to chronic Q fever.

Jansen AFM, Schoffelen T, Bleeker-Rovers CP, Wever PC, Jaeger M, Oosting M, Adriaans A, Joosten LAB, Netea MG, van Deuren M, van de Vosse E.

Clin Microbiol Infect. 2019 Jan 4. pii: S1198-743X(18)30585-8. doi: 10.1016/j.cmi.2018.08.011. [Epub ahead of print]

PMID:
30616015
14.

T-Cell Lymphopenia in Patients with Advanced Thyroid Carcinoma Is Associated with Poor Prognosis.

Rabold K, Gielen PR, Kers-Rebel ED, Netea MG, Smit JWA, Adema GJ, Netea-Maier RT.

Oncologist. 2019 Jan 3. pii: theoncologist.2018-0422. doi: 10.1634/theoncologist.2018-0422. [Epub ahead of print]

PMID:
30606882
15.

Treatment With Acetylsalicylic Acid Reverses Endotoxin Tolerance in Humans In Vivo: A Randomized Placebo-Controlled Study.

Leijte GP, Kiers D, van der Heijden W, Jansen A, Gerretsen J, Boerrigter V, Netea MG, Kox M, Pickkers P.

Crit Care Med. 2018 Dec 21. doi: 10.1097/CCM.0000000000003630. [Epub ahead of print]

PMID:
30585832
16.

Trained Immunity Characteristics Are Associated With Progressive Cerebral Small Vessel Disease.

Noz MP, Ter Telgte A, Wiegertjes K, Joosten LAB, Netea MG, de Leeuw FE, Riksen NP.

Stroke. 2018 Dec;49(12):2910-2917. doi: 10.1161/STROKEAHA.118.023192.

PMID:
30571420
17.

DNA Synthesis Is Activated in Mosquitoes and Human Monocytes During the Induction of Innate Immune Memory.

Cime-Castillo J, Arts RJW, Vargas-Ponce de León V, Moreno-Torres R, Hernández-Martínez S, Recio-Totoro B, Claudio-Piedras F, Netea MG, Lanz-Mendoza H.

Front Immunol. 2018 Nov 30;9:2834. doi: 10.3389/fimmu.2018.02834. eCollection 2018.

18.

Intracellular Alarmins: Hidden dangers signals crucial for cancer, host defense and inflammatory processes.

Joosten LAB, Netea MG.

Semin Immunol. 2018 Aug;38:1-2. doi: 10.1016/j.smim.2018.10.007. Epub 2018 Oct 26. No abstract available.

PMID:
30554607
19.

The role of glutamine metabolism for host defense against Mycobacterium tuberculosis infection.

Koeken VACM, Lachmandas E, Riza A, Matzaraki V, Li Y, Kumar V, Oosting M, Joosten LAB, Netea MG, van Crevel R.

J Infect Dis. 2018 Dec 12. doi: 10.1093/infdis/jiy709. [Epub ahead of print]

PMID:
30541099
20.

PTEN Hamartoma Tumor Syndrome and Immune Dysregulation.

Eissing M, Ripken L, Schreibelt G, Westdorp H, Ligtenberg M, Netea-Maier R, Netea MG, de Vries IJM, Hoogerbrugge N.

Transl Oncol. 2019 Feb;12(2):361-367. doi: 10.1016/j.tranon.2018.11.003. Epub 2018 Nov 30. Review.

21.

Trained Immunity and Local Innate Immune Memory in the Lung.

Netea MG, Joosten LAB.

Cell. 2018 Nov 29;175(6):1463-1465. doi: 10.1016/j.cell.2018.11.007.

PMID:
30500533
22.

The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans.

Tunjungputri RN, Li Y, de Groot PG, Dinarello CA, Smeekens SP, Jaeger M, Doppenberg-Oosting M, Cruijsen M, Lemmers H, Toenhake-Dijkstra H, Aguirre-Gamboa R, Kumar V, Wijmenga C, Joosten LAB, Netea MG, van der Ven A, de Mast Q.

Thromb Haemost. 2018 Dec;118(12):2112-2125. doi: 10.1055/s-0038-1675603. Epub 2018 Nov 19.

PMID:
30453346
23.

H4:IC31 Vaccine or BCG Revaccination for Tuberculosis.

de Bree C, van Crevel R, Netea MG.

N Engl J Med. 2018 Nov 15;379(20):1969. doi: 10.1056/NEJMc1811046. No abstract available.

PMID:
30428296
24.

Increased NEFA levels reduce blood Mg2+ in hypertriacylglycerolaemic states via direct binding of NEFA to Mg2.

Kurstjens S, de Baaij JHF, Overmars-Bos C, van den Munckhof ICL, Garzero V, de Vries MA, Burggraaf B, van Diepen JA, Riksen NP, Rutten JHW, Netea MG, Castro Cabezas M, Bindels RJM, Ashcroft FM, Tack CJJ, Hoenderop JGJ.

Diabetologia. 2019 Feb;62(2):311-321. doi: 10.1007/s00125-018-4771-3. Epub 2018 Nov 13.

25.

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.

Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J.

Immunity. 2018 Nov 20;49(5):819-828.e6. doi: 10.1016/j.immuni.2018.09.008. Epub 2018 Nov 6.

PMID:
30413362
26.

Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling.

Pradhan A, Avelar GM, Bain JM, Childers DS, Larcombe DE, Netea MG, Shekhova E, Munro CA, Brown GD, Erwig LP, Gow NAR, Brown AJP.

MBio. 2018 Nov 6;9(6). pii: e01318-18. doi: 10.1128/mBio.01318-18.

27.

Phase I/II Trial of a Combination of Anti-CD3/CD7 Immunotoxins for Steroid-Refractory Acute Graft-versus-Host Disease.

Groth C, van Groningen LFJ, Matos TR, Bremmers ME, Preijers FWMB, Dolstra H, Reicherts C, Schaap NPM, van Hooren EHG, IntHout J, Masereeuw R, Netea MG, Levine JE, Morales G, Ferrara JL, Blijlevens NMA, van Oosterhout YVJM, Stelljes M, van der Velden WJFM.

Biol Blood Marrow Transplant. 2018 Nov 3. pii: S1083-8791(18)30691-8. doi: 10.1016/j.bbmt.2018.10.020. [Epub ahead of print]

PMID:
30399420
28.

Corrigendum: Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice.

de Bree LCJ, Marijnissen RJ, Kel JM, Rosendahl Huber SK, Aaby P, Benn CS, Wijnands MVW, Diavatopoulos DA, van Crevel R, Joosten LAB, Netea MG, Dulos J.

Front Immunol. 2018 Oct 25;9:2471. doi: 10.3389/fimmu.2018.02471. eCollection 2018.

29.

Author Correction: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome.

Zhernakova DV, Le TH, Kurilshikov A, Atanasovska B, Bonder MJ, Sanna S, Claringbould A, Võsa U, Deelen P, Franke L, de Boer RA, Kuipers F, Netea MG, Hofker MH, Wijmenga C, Zhernakova A, Fu J; LifeLines cohort study; BIOS consortium.

Nat Genet. 2018 Dec;50(12):1752. doi: 10.1038/s41588-018-0275-9.

PMID:
30341443
30.

Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus.

Stienstra R, Netea MG.

Trends Endocrinol Metab. 2018 Dec;29(12):813-814. doi: 10.1016/j.tem.2018.10.001. Epub 2018 Oct 13.

PMID:
30327169
31.

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.

Domínguez-Andrés J, Novakovic B, Li Y, Scicluna BP, Gresnigt MS, Arts RJW, Oosting M, Moorlag SJCFM, Groh LA, Zwaag J, Koch RM, Ter Horst R, Joosten LAB, Wijmenga C, Michelucci A, van der Poll T, Kox M, Pickkers P, Kumar V, Stunnenberg H, Netea MG.

Cell Metab. 2019 Jan 8;29(1):211-220.e5. doi: 10.1016/j.cmet.2018.09.003. Epub 2018 Oct 4.

PMID:
30293776
32.

Induction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G.

van Splunter M, van Osch TLJ, Brugman S, Savelkoul HFJ, Joosten LAB, Netea MG, van Neerven RJJ.

Nutrients. 2018 Sep 27;10(10). pii: E1378. doi: 10.3390/nu10101378.

33.

Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome.

Zhernakova DV, Le TH, Kurilshikov A, Atanasovska B, Bonder MJ, Sanna S, Claringbould A, Võsa U, Deelen P, Franke L, de Boer RA, Kuipers F, Netea MG, Hofker MH, Wijmenga C, Zhernakova A, Fu J; LifeLines cohort study; BIOS consortium.

Nat Genet. 2018 Nov;50(11):1524-1532. doi: 10.1038/s41588-018-0224-7. Epub 2018 Sep 24. Erratum in: Nat Genet. 2018 Oct 19;:.

PMID:
30250126
34.

Induction of innate immune memory: the role of cellular metabolism.

Domínguez-Andrés J, Joosten LA, Netea MG.

Curr Opin Immunol. 2018 Sep 18;56:10-16. doi: 10.1016/j.coi.2018.09.001. [Epub ahead of print] Review.

PMID:
30240964
35.

Getting to the marrow of trained immunity.

Groh L, Netea MG, Riksen NP, Keating ST.

Epigenomics. 2018 Sep;10(9):1151-1154. doi: 10.2217/epi-2018-0098. No abstract available.

PMID:
30238777
36.

Genetic variant in IL-32 is associated with the ex vivo cytokine production of anti-TNF treated PBMCs from rheumatoid arthritis patients.

Damen MSMA, Schraa K, Tweehuysen L, den Broeder AA, Netea MG, Popa CD, Joosten LAB.

Sci Rep. 2018 Sep 19;8(1):14050. doi: 10.1038/s41598-018-32485-0.

37.

Be aware, innate immune cells remember.

Riksen NP, Netea MG.

Aging (Albany NY). 2018 Sep 12;10(9):2218-2219. doi: 10.18632/aging.101552. No abstract available.

38.

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.

Truax AD, Chen L, Tam JW, Cheng N, Guo H, Koblansky AA, Chou WC, Wilson JE, Brickey WJ, Petrucelli A, Liu R, Cooper DE, Koenigsknecht MJ, Young VB, Netea MG, Stienstra R, Sartor RB, Montgomery SA, Coleman RA, Ting JP.

Cell Host Microbe. 2018 Sep 12;24(3):364-378.e6. doi: 10.1016/j.chom.2018.08.009.

PMID:
30212649
39.

T Cell Metabolism Has Evolved to Tolerate Tuberculosis.

Koeken VACM, van Crevel R, Netea MG.

Cell Metab. 2018 Sep 4;28(3):332-333. doi: 10.1016/j.cmet.2018.08.015.

PMID:
30184482
40.

The impact of sex hormones on BCG-induced trained immunity.

de Bree LCJ, Janssen R, Aaby P, van Crevel R, Joosten LAB, Benn CS, Netea MG.

J Leukoc Biol. 2018 Sep;104(3):573-578. doi: 10.1002/JLB.5MA0118-027R.

PMID:
30153369
41.

Role of gut microbiota in chronic low-grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies.

van den Munckhof ICL, Kurilshikov A, Ter Horst R, Riksen NP, Joosten LAB, Zhernakova A, Fu J, Keating ST, Netea MG, de Graaf J, Rutten JHW.

Obes Rev. 2018 Dec;19(12):1719-1734. doi: 10.1111/obr.12750. Epub 2018 Aug 24.

PMID:
30144260
42.

Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival.

McCall CE, Zabalawi M, Liu T, Martin A, Long DL, Buechler NL, Arts RJW, Netea M, Yoza BK, Stacpoole PW, Vachharajani V.

JCI Insight. 2018 Aug 9;3(15). pii: 99292. doi: 10.1172/jci.insight.99292. [Epub ahead of print]

43.

HDAC inhibitors modulate innate immune responses to micro-organisms relevant to chronic mucocutaneous candidiasis.

Rösler B, Wang X, Keating ST, Joosten LAB, Netea MG, van de Veerdonk FL.

Clin Exp Immunol. 2018 Nov;194(2):205-219. doi: 10.1111/cei.13192. Epub 2018 Oct 1.

PMID:
30069986
44.

Host Genetic Signatures of Susceptibility to Fungal Disease.

Campos CF, van de Veerdonk FL, Gonçalves SM, Cunha C, Netea MG, Carvalho A.

Curr Top Microbiol Immunol. 2018 Jul 25. doi: 10.1007/82_2018_113. [Epub ahead of print]

PMID:
30043341
45.

Non-specific effects of vaccines: Current evidence and potential implications.

de Bree LCJ, Koeken VACM, Joosten LAB, Aaby P, Benn CS, van Crevel R, Netea MG.

Semin Immunol. 2018 Oct;39:35-43. doi: 10.1016/j.smim.2018.06.002. Epub 2018 Jul 11. Review.

PMID:
30007489
46.

Long-term reprogramming of the innate immune system.

Dominguez-Andres J, Netea MG.

J Leukoc Biol. 2019 Feb;105(2):329-338. doi: 10.1002/JLB.MR0318-104R. Epub 2018 Jul 12. Review.

PMID:
29999546
47.

Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation.

Kiers D, Wielockx B, Peters E, van Eijk LT, Gerretsen J, John A, Janssen E, Groeneveld R, Peters M, Damen L, Meneses AM, Krüger A, Langereis JD, Zomer AL, Blackburn MR, Joosten LA, Netea MG, Riksen NP, van der Hoeven JG, Scheffer GJ, Eltzschig HK, Pickkers P, Kox M.

EBioMedicine. 2018 Jul;33:144-156. doi: 10.1016/j.ebiom.2018.06.021. Epub 2018 Jul 4.

48.

The causes and consequences of variation in human cytokine production in health.

Schirmer M, Kumar V, Netea MG, Xavier RJ.

Curr Opin Immunol. 2018 Oct;54:50-58. doi: 10.1016/j.coi.2018.05.012. Epub 2018 Jun 15. Review.

PMID:
29913309
49.

Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome.

Raijmakers RPH, Jansen AFM, Keijmel SP, Schoffelen T, Scholzen A, van der Meer JWM, Joosten LAB, Netea MG, van Deuren M, Bleeker-Rovers CP.

Eur J Clin Microbiol Infect Dis. 2018 Jul;37(7):1385-1391. doi: 10.1007/s10096-018-3265-z. Epub 2018 May 26.

50.

Antifungal immune responses: emerging host-pathogen interactions and translational implications.

Kumar V, van de Veerdonk FL, Netea MG.

Genome Med. 2018 May 25;10(1):39. doi: 10.1186/s13073-018-0553-2. Review.

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