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Items: 38

1.

Editorial overview: New pieces in the redox puzzle: oxidative and reductive transformations in biotechnology.

Vincent KA, Nestl BM.

Curr Opin Chem Biol. 2019 Apr;49:A1-A3. doi: 10.1016/j.cbpa.2019.02.008. Epub 2019 Mar 15. No abstract available.

PMID:
30885748
2.

Asymmetric Enzymatic Hydration of Unactivated, Aliphatic Alkenes.

Demming RM, Hammer SC, Nestl BM, Gergel S, Fademrecht S, Pleiss J, Hauer B.

Angew Chem Int Ed Engl. 2019 Jan 2;58(1):173-177. doi: 10.1002/anie.201810005. Epub 2018 Nov 30.

3.

New imine-reducing enzymes from β-hydroxyacid dehydrogenases by single amino acid substitutions.

Lenz M, Fademrecht S, Sharma M, Pleiss J, Grogan G, Nestl BM.

Protein Eng Des Sel. 2018 Apr 1;31(4):109-120. doi: 10.1093/protein/gzy006.

PMID:
29733377
4.

Biocatalyst Screening with a Twist: Application of Oxygen Sensors Integrated in Microchannels for Screening Whole Cell Biocatalyst Variants.

Fernandes AC, Halder JM, Nestl BM, Hauer B, Gernaey KV, Krühne U.

Bioengineering (Basel). 2018 Apr 9;5(2). pii: E30. doi: 10.3390/bioengineering5020030.

5.

Recent advances in imine reductase-catalyzed reactions.

Lenz M, Borlinghaus N, Weinmann L, Nestl BM.

World J Microbiol Biotechnol. 2017 Oct 11;33(11):199. doi: 10.1007/s11274-017-2365-8. Review.

PMID:
29022156
6.

Enzymatic Addition of Alcohols to Terpenes by Squalene Hopene Cyclase Variants.

Kühnel LC, Nestl BM, Hauer B.

Chembiochem. 2017 Nov 16;18(22):2222-2225. doi: 10.1002/cbic.201700449. Epub 2017 Oct 2.

PMID:
28898524
7.

Structural and functional insights into asymmetric enzymatic dehydration of alkenols.

Nestl BM, Geinitz C, Popa S, Rizek S, Haselbeck RJ, Stephen R, Noble MA, Fischer MP, Ralph EC, Hau HT, Man H, Omar M, Turkenburg JP, van Dien S, Culler SJ, Grogan G, Hauer B.

Nat Chem Biol. 2017 Mar;13(3):275-281. doi: 10.1038/nchembio.2271. Epub 2017 Jan 9.

8.

Asymmetric Ketone Reduction by Imine Reductases.

Lenz M, Meisner J, Quertinmont L, Lutz S, Kästner J, Nestl BM.

Chembiochem. 2017 Feb 1;18(3):253-256. doi: 10.1002/cbic.201600647. Epub 2016 Dec 30.

PMID:
27911981
9.
10.

Squalene-hopene cyclases-evolution, dynamics and catalytic scope.

Syrén PO, Henche S, Eichler A, Nestl BM, Hauer B.

Curr Opin Struct Biol. 2016 Dec;41:73-82. doi: 10.1016/j.sbi.2016.05.019. Epub 2016 Jun 20. Review.

PMID:
27336183
11.

Cultivation and purification of two stereoselective imine reductases from Streptosporangium roseum and Paenibacillus elgii.

Lenz M, Scheller PN, Richter SM, Hauer B, Nestl BM.

Protein Expr Purif. 2017 May;133:199-204. doi: 10.1016/j.pep.2016.05.003. Epub 2016 May 5.

PMID:
27157442
12.

Loop-Grafted Old Yellow Enzymes in the Bienzymatic Cascade Reduction of Allylic Alcohols.

Reich S, Nestl BM, Hauer B.

Chembiochem. 2016 Apr 1;17(7):561-5. doi: 10.1002/cbic.201500604. Epub 2016 Feb 23.

PMID:
27037735
13.

Identification of imine reductase-specific sequence motifs.

Fademrecht S, Scheller PN, Nestl BM, Hauer B, Pleiss J.

Proteins. 2016 May;84(5):600-10. doi: 10.1002/prot.25008. Epub 2016 Mar 6.

PMID:
26857686
14.

H2-driven biotransformation of n-octane to 1-octanol by a recombinant Pseudomonas putida strain co-synthesizing an O2-tolerant hydrogenase and a P450 monooxygenase.

Lonsdale TH, Lauterbach L, Honda Malca S, Nestl BM, Hauer B, Lenz O.

Chem Commun (Camb). 2015 Nov 21;51(90):16173-5. doi: 10.1039/c5cc06078h.

PMID:
26394141
15.

Engineering Rieske Non-Heme Iron Oxygenases for the Asymmetric Dihydroxylation of Alkenes.

Gally C, Nestl BM, Hauer B.

Angew Chem Int Ed Engl. 2015 Oct 26;54(44):12952-6. doi: 10.1002/anie.201506527. Epub 2015 Sep 9.

PMID:
26351244
16.

Activity of squalene-hopene cyclases in bicontinuous microemulsions.

Steudle AK, Nestl BM, Hauer B, Stubenrauch C.

Colloids Surf B Biointerfaces. 2015 Nov 1;135:735-41. doi: 10.1016/j.colsurfb.2015.08.034. Epub 2015 Aug 22.

PMID:
26340363
17.

Hydrolysis of hydrophobic esters in a bicontinuous microemulsion catalysed by lipase B from Candida antarctica.

Steudle AK, Subinya M, Nestl BM, Stubenrauch C.

Chemistry. 2015 Feb 2;21(6):2691-700. doi: 10.1002/chem.201405335. Epub 2014 Dec 15.

PMID:
25512180
18.

Squalene hopene cyclases are protonases for stereoselective Brønsted acid catalysis.

Hammer SC, Marjanovic A, Dominicus JM, Nestl BM, Hauer B.

Nat Chem Biol. 2015 Feb;11(2):121-6. doi: 10.1038/nchembio.1719. Epub 2014 Dec 15.

PMID:
25503928
19.

Biooxidation of n-butane to 1-butanol by engineered P450 monooxygenase under increased pressure.

Nebel BA, Scheps D, Honda Malca S, Nestl BM, Breuer M, Wagner HG, Breitscheidel B, Kratz D, Hauer B.

J Biotechnol. 2014 Dec 10;191:86-92. doi: 10.1016/j.jbiotec.2014.08.022. Epub 2014 Aug 26.

PMID:
25169664
20.

Enzyme toolbox: novel enantiocomplementary imine reductases.

Scheller PN, Fademrecht S, Hofelzer S, Pleiss J, Leipold F, Turner NJ, Nestl BM, Hauer B.

Chembiochem. 2014 Oct 13;15(15):2201-4. doi: 10.1002/cbic.201402213. Epub 2014 Aug 27.

PMID:
25163890
21.

Physicochemical aspects of lipase B from Candida antarctica in bicontinuous microemulsions.

Subinya M, Steudle AK, Nestl B, Nebel B, Hauer B, Stubenrauch C, Engelskirchen S.

Langmuir. 2014 Mar 25;30(11):2993-3000. doi: 10.1021/la4042088. Epub 2014 Mar 11.

PMID:
24564515
22.

New generation of biocatalysts for organic synthesis.

Nestl BM, Hammer SC, Nebel BA, Hauer B.

Angew Chem Int Ed Engl. 2014 Mar 17;53(12):3070-95. doi: 10.1002/anie.201302195. Epub 2014 Feb 12. Review.

PMID:
24520044
23.

Synthesis of ω-hydroxy dodecanoic acid based on an engineered CYP153A fusion construct.

Scheps D, Honda Malca S, Richter SM, Marisch K, Nestl BM, Hauer B.

Microb Biotechnol. 2013 Nov;6(6):694-707. doi: 10.1111/1751-7915.12073. Epub 2013 Aug 14.

24.

Synthesis of 9-oxononanoic acid, a precursor for biopolymers.

Otte KB, Kirtz M, Nestl BM, Hauer B.

ChemSusChem. 2013 Nov;6(11):2149-56. doi: 10.1002/cssc.201300183. Epub 2013 Aug 9.

PMID:
23934656
25.

Protein engineering: Chemistry gets the assist.

Nestl BM, Hauer B.

Nat Chem Biol. 2013 Aug;9(8):470-1. doi: 10.1038/nchembio.1291. Epub 2013 Jun 23.

PMID:
23792735
26.

Variations in the stability of NCR ene reductase by rational enzyme loop modulation.

Reich S, Kress N, Nestl BM, Hauer B.

J Struct Biol. 2014 Feb;185(2):228-33. doi: 10.1016/j.jsb.2013.04.004. Epub 2013 Apr 17.

PMID:
23602815
27.

Squalene hopene cyclases: highly promiscuous and evolvable catalysts for stereoselective CC and CX bond formation.

Hammer SC, Syrén PO, Seitz M, Nestl BM, Hauer B.

Curr Opin Chem Biol. 2013 Apr;17(2):293-300. doi: 10.1016/j.cbpa.2013.01.016. Epub 2013 Feb 26. Review.

PMID:
23485581
28.

Synthesis of heterocyclic terpenoids by promiscuous squalene-hopene cyclases.

Seitz M, Syrén PO, Steiner L, Klebensberger J, Nestl BM, Hauer B.

Chembiochem. 2013 Mar 4;14(4):436-9. doi: 10.1002/cbic.201300018. Epub 2013 Feb 18.

PMID:
23418022
29.

Crystal structure determination and mutagenesis analysis of the ene reductase NCR.

Reich S, Hoeffken HW, Rosche B, Nestl BM, Hauer B.

Chembiochem. 2012 Nov 5;13(16):2400-7. doi: 10.1002/cbic.201200404. Epub 2012 Oct 2.

PMID:
23033175
30.

Bacterial CYP153A monooxygenases for the synthesis of omega-hydroxylated fatty acids.

Honda Malca S, Scheps D, Kühnel L, Venegas-Venegas E, Seifert A, Nestl BM, Hauer B.

Chem Commun (Camb). 2012 May 25;48(42):5115-7. doi: 10.1039/c2cc18103g. Epub 2012 Apr 19.

PMID:
22513828
31.

Regioselective ω-hydroxylation of medium-chain n-alkanes and primary alcohols by CYP153 enzymes from Mycobacterium marinum and Polaromonas sp. strain JS666.

Scheps D, Malca SH, Hoffmann H, Nestl BM, Hauer B.

Org Biomol Chem. 2011 Oct 7;9(19):6727-33. doi: 10.1039/c1ob05565h. Epub 2011 Aug 12.

PMID:
21837346
32.

Recent progress in industrial biocatalysis.

Nestl BM, Nebel BA, Hauer B.

Curr Opin Chem Biol. 2011 Apr;15(2):187-93. doi: 10.1016/j.cbpa.2010.11.019. Epub 2010 Dec 30. Review.

PMID:
21195018
33.

Emulation of racemase activity by employing a pair of stereocomplementary biocatalysts.

Gruber CC, Nestl BM, Gross J, Hildebrandt P, Bornscheuer UT, Faber K, Kroutil W.

Chemistry. 2007;13(29):8271-6.

PMID:
17639544
34.

Biocatalytic racemization of sec-alcohols and alpha-hydroxyketones using lyophilized microbial cells.

Nestl BM, Voss CV, Bodlenner A, Ellmer-Schaumberger U, Kroutil W, Faber K.

Appl Microbiol Biotechnol. 2007 Oct;76(5):1001-8. Epub 2007 Jul 13.

PMID:
17628797
35.

Biocatalytic approaches for the quantitative production of single stereoisomers from racemates.

Gadler P, Glueck SM, Kroutil W, Nestl BM, Larissegger-Schnell B, Ueberbacher BT, Wallner SR, Faber K.

Biochem Soc Trans. 2006 Apr;34(Pt 2):296-300. Review.

PMID:
16545098
36.

Highly enantioselective stereo-inverting sec-alkylsulfatase activity of hyperthermophilic Archaea.

Wallner SR, Nestl BM, Faber K.

Org Biomol Chem. 2005 Jul 21;3(14):2652-6. Epub 2005 Jun 21.

PMID:
15999201
37.

Biocatalytic racemization of aliphatic, arylaliphatic, and aromatic alpha-hydroxycarboxylic acids.

Glueck SM, Pirker M, Nestl BM, Ueberbacher BT, Larissegger-Schnell B, Csar K, Hauer B, Stuermer R, Kroutil W, Faber K.

J Org Chem. 2005 May 13;70(10):4028-32.

PMID:
15876092
38.

Highly enantioselective sec-alkyl sulfatase activity of Sulfolobus acidocaldarius DSM 639.

Wallner SR, Nestl BM, Faber K.

Org Lett. 2004 Dec 23;6(26):5009-10.

PMID:
15606122

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