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N-Terminal Truncated Myb with New Transcriptional Activity Produced Through Use of an Alternative MYB Promoter in Salivary Gland Adenoid Cystic Carcinoma.

Frerich CA, Sedam HN, Kang H, Mitani Y, El-Naggar AK, Ness SA.

Cancers (Basel). 2019 Dec 21;12(1). pii: E45. doi: 10.3390/cancers12010045.


Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia.

Sharma ND, Nickl CK, Kang H, Ornatowski W, Brown R, Ness SA, Loh ML, Mullighan CG, Winter SS, Hunger SP, Cannon JL, Matlawska-Wasowska K.

Cancer Sci. 2019 Jun;110(6):1931-1946. doi: 10.1111/cas.14021. Epub 2019 May 3.


Tumor Heterogeneity as a Predictor of Response to Neoadjuvant Chemotherapy in Locally Advanced Rectal Cancer.

Greenbaum A, Martin DR, Bocklage T, Lee JH, Ness SA, Rajput A.

Clin Colorectal Cancer. 2019 Jun;18(2):102-109. doi: 10.1016/j.clcc.2019.02.003. Epub 2019 Feb 13.


Transcriptomes define distinct subgroups of salivary gland adenoid cystic carcinoma with different driver mutations and outcomes.

Frerich CA, Brayer KJ, Painter BM, Kang H, Mitani Y, El-Naggar AK, Ness SA.

Oncotarget. 2017 Dec 23;9(7):7341-7358. doi: 10.18632/oncotarget.23641. eCollection 2018 Jan 26.


Editorial: Targeting MYB Oncogene Expression in Adenoid Cystic Carcinoma.

Ness SA.

J Natl Cancer Inst. 2017 Sep 1;109(9). doi: 10.1093/jnci/djx054. No abstract available.


Optimized approach for Ion Proton RNA sequencing reveals details of RNA splicing and editing features of the transcriptome.

Brown RB, Madrid NJ, Suzuki H, Ness SA.

PLoS One. 2017 May 1;12(5):e0176675. doi: 10.1371/journal.pone.0176675. eCollection 2017.


Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast.

Young CP, Hillyer C, Hokamp K, Fitzpatrick DJ, Konstantinov NK, Welty JS, Ness SA, Werner-Washburne M, Fleming AB, Osley MA.

BMC Genomics. 2017 Jan 26;18(1):107. doi: 10.1186/s12864-017-3509-9.


Mutant-Allele Tumor Heterogeneity Scores Correlate With Risk of Metastases in Colon Cancer.

Rajput A, Bocklage T, Greenbaum A, Lee JH, Ness SA.

Clin Colorectal Cancer. 2017 Sep;16(3):e165-e170. doi: 10.1016/j.clcc.2016.11.004. Epub 2016 Nov 23.


Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia.

Mayfield JR, Czuchlewski DR, Gale JM, Matlawska-Wasowska K, Vasef MA, Nickl C, Pickett G, Ness SA, Winter SS.

Pediatr Blood Cancer. 2017 May;64(5). doi: 10.1002/pbc.26328. Epub 2016 Nov 15.


MLL rearrangements impact outcome in HOXA-deregulated T-lineage acute lymphoblastic leukemia: a Children's Oncology Group Study.

Matlawska-Wasowska K, Kang H, Devidas M, Wen J, Harvey RC, Nickl CK, Ness SA, Rusch M, Li Y, Onozawa M, Martinez C, Wood BL, Asselin BL, Chen IM, Roberts KG, Baruchel A, Soulier J, Dombret H, Zhang J, Larson RS, Raetz EA, Carroll WL, Winick NJ, Aplan PD, Loh ML, Mullighan CG, Hunger SP, Heerema NA, Carroll AJ, Dunsmore KP, Winter SS.

Leukemia. 2016 Sep;30(9):1909-12. doi: 10.1038/leu.2016.60. Epub 2016 Mar 8. No abstract available.


Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma.

Brayer KJ, Frerich CA, Kang H, Ness SA.

Cancer Discov. 2016 Feb;6(2):176-87. doi: 10.1158/2159-8290.CD-15-0859. Epub 2015 Dec 2.


Situational awareness: regulation of the myb transcription factor in differentiation, the cell cycle and oncogenesis.

George OL, Ness SA.

Cancers (Basel). 2014 Oct 2;6(4):2049-71. doi: 10.3390/cancers6042049. Review.


Transdiaphragmatic hepatic and pulmonary abscess attributed to ileal diverticulitis in a horse.

Ruby R, Buckles E, Pinn T, Ness SA, Yeager AE, Ainsworth DM.

J Vet Intern Med. 2013 Nov-Dec;27(6):1633-6. doi: 10.1111/jvim.12205. Epub 2013 Oct 1. No abstract available.


RNA editing events in mitochondrial genes by ultra-deep sequencing methods: a comparison of cytoplasmic male sterile, fertile and restored genotypes in cotton.

Suzuki H, Yu J, Ness SA, O'Connell MA, Zhang J.

Mol Genet Genomics. 2013 Sep;288(9):445-57. doi: 10.1007/s00438-013-0764-6. Epub 2013 Jun 29.


Single molecule analysis of c-myb alternative splicing reveals novel classifiers for precursor B-ALL.

Zhou YE, O'Rourke JP, Edwards JS, Ness SA.

PLoS One. 2011;6(8):e22880. doi: 10.1371/journal.pone.0022880. Epub 2011 Aug 11.


GSI-I (Z-LLNle-CHO) inhibits ╬│-secretase and the proteosome to trigger cell death in precursor-B acute lymphoblastic leukemia.

Meng X, Matlawska-Wasowska K, Girodon F, Mazel T, Willman CL, Atlas S, Chen IM, Harvey RC, Hunger SP, Ness SA, Winter SS, Wilson BS.

Leukemia. 2011 Jul;25(7):1135-46. doi: 10.1038/leu.2011.50. Epub 2011 Apr 15.


Dramatic repositioning of c-Myb to different promoters during the cell cycle observed by combining cell sorting with chromatin immunoprecipitation.

Quintana AM, Zhou YE, Pena JJ, O'Rourke JP, Ness SA.

PLoS One. 2011 Feb 22;6(2):e17362. doi: 10.1371/journal.pone.0017362.


Identification and regulation of c-Myb target genes in MCF-7 cells.

Quintana AM, Liu F, O'Rourke JP, Ness SA.

BMC Cancer. 2011 Jan 25;11:30. doi: 10.1186/1471-2407-11-30.


Adult human CD133/1(+) kidney cells isolated from papilla integrate into developing kidney tubules.

Ward HH, Romero E, Welford A, Pickett G, Bacallao R, Gattone VH 2nd, Ness SA, Wandinger-Ness A, Roitbak T.

Biochim Biophys Acta. 2011 Oct;1812(10):1344-57. doi: 10.1016/j.bbadis.2011.01.010. Epub 2011 Jan 19.


Myb proteins: angels and demons in normal and transformed cells.

Zhou Y, Ness SA.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1109-31. Review.


Diagnostic accuracy of contrast echocardiography during adenosine stress for detection of abnormal myocardial perfusion: a prospective comparison with technetium-99 m sestamibi single-photon emission computed tomography.

Abdelmoneim SS, Bernier M, Dhoble A, Moir S, Hagen ME, Ness SA, Pellikka PA, Abdel-Kader SS, Mulvagh SL.

Heart Vessels. 2010 Mar;25(2):121-30. doi: 10.1007/s00380-009-1174-x. Epub 2010 Mar 26.


Assessment of myocardial perfusion during adenosine stress using real time three-dimensional and two-dimensional myocardial contrast echocardiography: comparison with single-photon emission computed tomography.

Abdelmoneim SS, Bernier M, Dhoble A, Moir S, Hagen ME, Ness SA, Abdel-Kader SS, Pellikka PA, Mulvagh SL.

Echocardiography. 2010 Apr;27(4):421-9. doi: 10.1111/j.1540-8175.2009.01026.x. Epub 2010 Mar 15.


Safety of contrast agent use during stress echocardiography in patients with elevated right ventricular systolic pressure: a cohort study.

Abdelmoneim SS, Bernier M, Scott CG, Dhoble A, Ness SA, Hagen ME, Moir S, McCully RB, Pellikka PA, Mulvagh SL.

Circ Cardiovasc Imaging. 2010 May;3(3):240-8. doi: 10.1161/CIRCIMAGING.109.895029. Epub 2010 Mar 16.


Microvascular function in Takotsubo cardiomyopathy with contrast echocardiography: prospective evaluation and review of literature.

Abdelmoneim SS, Mankad SV, Bernier M, Dhoble A, Hagen ME, Ness SA, Chandrasekaran K, Pellikka PA, Oh JK, Mulvagh SL.

J Am Soc Echocardiogr. 2009 Nov;22(11):1249-55. doi: 10.1016/j.echo.2009.07.012. Epub 2009 Sep 18. Review.


Safety of contrast agent use during stress echocardiography: a 4-year experience from a single-center cohort study of 26,774 patients.

Abdelmoneim SS, Bernier M, Scott CG, Dhoble A, Ness SA, Hagen ME, Moir S, McCully RB, Pellikka PA, Mulvagh SL.

JACC Cardiovasc Imaging. 2009 Sep;2(9):1048-56. doi: 10.1016/j.jcmg.2009.03.020.


Absolute myocardial blood flow determination using real-time myocardial contrast echocardiography during adenosine stress: comparison with single-photon emission computed tomography.

Abdelmoneim SS, Dhoble A, Bernier M, Moir S, Hagen ME, Ness SA, Abdel-Kader SS, Pellikka PA, Mulvagh SL.

Heart. 2009 Oct;95(20):1662-8. doi: 10.1136/hrt.2009.169268. Epub 2009 Jul 6.


Acute weight gain and diastolic dysfunction as a potent risk complex for post stem cell transplant atrial fibrillation.

Fatema K, Gertz MA, Barnes ME, Eisinger AD, Ness SA, Gersh BJ, Micallef IN, Seward JB, Cha SS, Bailey KR, Tsang TS.

Am J Hematol. 2009 Aug;84(8):499-503. doi: 10.1002/ajh.21459.


The SRD5A2 V89L polymorphism is associated with severity of disease in men with early onset prostate cancer.

Scariano JK, Treat E, Alba F, Nelson H, Ness SA, Smith AY.

Prostate. 2008 Dec 1;68(16):1798-805. doi: 10.1002/pros.20842.


Alternative RNA splicing produces multiple forms of c-Myb with unique transcriptional activities.

O'Rourke JP, Ness SA.

Mol Cell Biol. 2008 Mar;28(6):2091-101. doi: 10.1128/MCB.01870-07. Epub 2008 Jan 14.


Microarray analysis: basic strategies for successful experiments.

Ness SA.

Mol Biotechnol. 2007 Jul;36(3):205-19. Review.


Mip/LIN-9 regulates the expression of B-Myb and the induction of cyclin A, cyclin B, and CDK1.

Pilkinton M, Sandoval R, Song J, Ness SA, Colamonici OR.

J Biol Chem. 2007 Jan 5;282(1):168-75. Epub 2006 Nov 10.


Basic microarray analysis: strategies for successful experiments.

Ness SA.

Methods Mol Biol. 2006;316:13-33. Review.


Identification of a novel human tissue factor splice variant that is upregulated in tumor cells.

Chand HS, Ness SA, Kisiel W.

Int J Cancer. 2006 Apr 1;118(7):1713-20.


Oncogenic mutations cause dramatic, qualitative changes in the transcriptional activity of c-Myb.

Liu F, Lei W, O'Rourke JP, Ness SA.

Oncogene. 2006 Feb 2;25(5):795-805.


Positive and negative regulation of c-Myb by cyclin D1, cyclin-dependent kinases, and p27 Kip1.

Lei W, Liu F, Ness SA.

Blood. 2005 May 15;105(10):3855-61. Epub 2005 Feb 1.


Positive and negative determinants of target gene specificity in myb transcription factors.

Lei W, Rushton JJ, Davis LM, Liu F, Ness SA.

J Biol Chem. 2004 Jul 9;279(28):29519-27. Epub 2004 Apr 21.


A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells.

Roitbak T, Ward CJ, Harris PC, Bacallao R, Ness SA, Wandinger-Ness A.

Mol Biol Cell. 2004 Mar;15(3):1334-46. Epub 2004 Jan 12.


Myb protein specificity: evidence of a context-specific transcription factor code.

Ness SA.

Blood Cells Mol Dis. 2003 Sep-Oct;31(2):192-200.


Pim-1 phosphorylates the DNA binding domain of c-Myb.

Winn LM, Lei W, Ness SA.

Cell Cycle. 2003 May-Jun;2(3):258-62.


Distinct changes in gene expression induced by A-Myb, B-Myb and c-Myb proteins.

Rushton JJ, Davis LM, Lei W, Mo X, Leutz A, Ness SA.

Oncogene. 2003 Jan 16;22(2):308-13.


The MHC class II-associated chicken invariant chain shares functional properties with its mammalian homologs.

Bremnes B, Rode M, Gedde-Dahl M, Nordeng TW, Jacobsen J, Ness SA, Bakke O.

Exp Cell Res. 2000 Sep 15;259(2):360-9.


Myb binding proteins: regulators and cohorts in transformation.

Ness SA.

Oncogene. 1999 May 13;18(19):3039-46. Review.


Pim-1 kinase and p100 cooperate to enhance c-Myb activity.

Leverson JD, Koskinen PJ, Orrico FC, Rainio EM, Jalkanen KJ, Dash AB, Eisenman RN, Ness SA.

Mol Cell. 1998 Oct;2(4):417-25.


The Myb oncoprotein: regulating a regulator.

Ness SA.

Biochim Biophys Acta. 1996 Dec 9;1288(3):F123-39. No abstract available.


The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb.

Dash AB, Orrico FC, Ness SA.

Genes Dev. 1996 Aug 1;10(15):1858-69.


Gene regulation by NF-M and Myb during differentiation and leukemic transformation.

Kowenz-Leutz E, Ansieau S, Twamley G, Ness SA, Leutz A.

Immunobiology. 1995 Jul;193(2-4):356-62. Review. No abstract available.


C/EBP beta regulation of the tumor necrosis factor alpha gene.

Pope RM, Leutz A, Ness SA.

J Clin Invest. 1994 Oct;94(4):1449-55.


Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation.

Ness SA, Engel JD.

Curr Opin Genet Dev. 1994 Oct;4(5):718-24. Review.


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