Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 160

1.

Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium.

Oshida K, Vasani N, Jones C, Moore T, Hester S, Nesnow S, Auerbach S, Geter DR, Aleksunes LM, Thomas RS, Applegate D, Klaassen CD, Corton JC.

Nucl Recept Signal. 2015 Apr 27;13:e002. doi: 10.1621/nrs.13002. eCollection 2015.

2.

Concordance of transcriptional and apical benchmark dose levels for conazole-induced liver effects in mice.

Bhat VS, Hester SD, Nesnow S, Eastmond DA.

Toxicol Sci. 2013 Nov;136(1):205-15. doi: 10.1093/toxsci/kft182. Epub 2013 Aug 22.

PMID:
23970803
3.

Integration of toxicological approaches with "omic" and related technologies to elucidate mechanisms of carcinogenic action: propiconazole, an example.

Nesnow S.

Cancer Lett. 2013 Jun 28;334(1):20-7. doi: 10.1016/j.canlet.2012.11.003. Epub 2012 Nov 23. Review.

PMID:
23178453
4.

Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation.

Murphy LA, Moore T, Nesnow S.

Toxicol Appl Pharmacol. 2012 Apr 15;260(2):146-54. doi: 10.1016/j.taap.2012.02.003. Epub 2012 Feb 14.

PMID:
22361350
5.

The hepatocarcinogenic conazoles: cyproconazole, epoxiconazole, and propiconazole induce a common set of toxicological and transcriptional responses.

Hester S, Moore T, Padgett WT, Murphy L, Wood CE, Nesnow S.

Toxicol Sci. 2012 May;127(1):54-65. doi: 10.1093/toxsci/kfs086. Epub 2012 Feb 14.

PMID:
22334560
6.

Propiconazole increases reactive oxygen species levels in mouse hepatic cells in culture and in mouse liver by a cytochrome P450 enzyme mediated process.

Nesnow S, Grindstaff RD, Lambert G, Padgett WT, Bruno M, Ge Y, Chen PJ, Wood CE, Murphy L.

Chem Biol Interact. 2011 Oct 15;194(1):79-89. doi: 10.1016/j.cbi.2011.08.002. Epub 2011 Aug 16.

PMID:
21864511
7.

Propiconazole induces alterations in the hepatic metabolome of mice: relevance to propiconazole-induced hepatocarcinogenesis.

Nesnow S, Padgett WT, Moore T.

Toxicol Sci. 2011 Apr;120(2):297-309. doi: 10.1093/toxsci/kfr012. Epub 2011 Jan 27.

PMID:
21278054
8.

Lack of contribution of covalent benzo[a]pyrene-7,8-quinone-DNA adducts in benzo[a]pyrene-induced mouse lung tumorigenesis.

Nesnow S, Nelson G, Padgett WT, George MH, Moore T, King LC, Adams LD, Ross JA.

Chem Biol Interact. 2010 Jul 30;186(2):157-65. doi: 10.1016/j.cbi.2010.03.037. Epub 2010 Mar 25.

PMID:
20346927
9.

Proteomic analysis of propiconazole responses in mouse liver: comparison of genomic and proteomic profiles.

Ortiz PA, Bruno ME, Moore T, Nesnow S, Winnik W, Ge Y.

J Proteome Res. 2010 Mar 5;9(3):1268-78. doi: 10.1021/pr900755q.

PMID:
20095644
10.

Protein carbonyl formation in response to propiconazole-induced oxidative stress.

Bruno M, Moore T, Nesnow S, Ge Y.

J Proteome Res. 2009 Apr;8(4):2070-8. doi: 10.1021/pr801061r.

PMID:
19714882
11.

Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression.

Nesnow S, Ward W, Moore T, Ren H, Hester SD.

Toxicol Sci. 2009 Jul;110(1):68-83. doi: 10.1093/toxsci/kfp076. Epub 2009 Apr 10.

PMID:
19363144
12.

Mutagenicity, stable DNA adducts, and abasic sites induced in Salmonella by phenanthro[3,4-b]- and phenanthro[4,3-b]thiophenes, sulfur analogs of benzo[c]phenanthrene.

Swartz CD, King LC, Nesnow S, Umbach DM, Kumar S, Sikka H, Demarini DM.

Mutat Res. 2009 Feb 10;661(1-2):47-56. doi: 10.1016/j.mrfmmm.2008.11.001. Epub 2008 Nov 12. Erratum in: Mutat Res. 2010 Oct 13;692(1-2):66. Sikka, Harish [added].

13.

Three conazoles increase hepatic microsomal retinoic acid metabolism and decrease mouse hepatic retinoic acid levels in vivo.

Chen PJ, Padgett WT, Moore T, Winnik W, Lambert GR, Thai SF, Hester SD, Nesnow S.

Toxicol Appl Pharmacol. 2009 Jan 15;234(2):143-55. doi: 10.1016/j.taap.2008.10.004. Epub 2008 Oct 29.

PMID:
19010342
14.

Cytotoxic effects of propiconazole and its metabolites in mouse and human hepatoma cells and primary mouse hepatocytes.

Chen PJ, Moore T, Nesnow S.

Toxicol In Vitro. 2008 Sep;22(6):1476-83. doi: 10.1016/j.tiv.2008.05.001. Epub 2008 May 13.

PMID:
18585002
15.

Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide.

Hester SD, Nesnow S.

Toxicol Appl Pharmacol. 2008 Mar 15;227(3):357-69. doi: 10.1016/j.taap.2007.10.030. Epub 2007 Nov 28.

PMID:
18164361
16.

Induction of cytochrome P450 enzymes in rat liver by two conazoles, myclobutanil and triadimefon.

Sun G, Grindstaff RD, Thai SF, Lambert GR, Tully DB, Dix DJ, Nesnow S.

Xenobiotica. 2007 Feb;37(2):180-93.

PMID:
17484520
17.

Toxicity profiles in rats treated with tumorigenic and nontumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.

Wolf DC, Allen JW, George MH, Hester SD, Sun G, Moore T, Thai SF, Delker D, Winkfield E, Leavitt S, Nelson G, Roop BC, Jones C, Thibodeaux J, Nesnow S.

Toxicol Pathol. 2006;34(7):895-902.

PMID:
17178690
19.
20.

Toxicity profiles in mice treated with hepatotumorigenic and non-hepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.

Allen JW, Wolf DC, George MH, Hester SD, Sun G, Thai SF, Delker DA, Moore T, Jones C, Nelson G, Roop BC, Leavitt S, Winkfield E, Ward WO, Nesnow S.

Toxicol Pathol. 2006;34(7):853-62.

PMID:
17178687
21.

Characterization of naphtho[1,2-a]pyrene and naphtho[1,2-e]pyrene DNA adducts in C3H10T1/2 fibroblasts.

Nelson G, Ross JA, Pimentel M, Desai D, Sharma AK, Amin S, Nesnow S.

Cancer Lett. 2007 Mar 18;247(2):309-17. Epub 2006 Jun 30.

PMID:
16814461
22.

Benzo[a]pyrene-7,8-quinone-3'-mononucleotide adduct standards for 32P postlabeling analyses: detection of benzo[a]pyrene-7,8-quinone-calf thymus DNA adducts.

Balu N, Padgett WT, Nelson GB, Lambert GR, Ross JA, Nesnow S.

Anal Biochem. 2006 Aug 15;355(2):213-23. Epub 2006 Jun 5.

PMID:
16797471
23.

Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides.

Goetz AK, Bao W, Ren H, Schmid JE, Tully DB, Wood C, Rockett JC, Narotsky MG, Sun G, Lambert GR, Thai SF, Wolf DC, Nesnow S, Dix DJ.

Toxicol Appl Pharmacol. 2006 Sep 15;215(3):274-84. Epub 2006 May 26.

PMID:
16730040
24.

Fluconazole-induced hepatic cytochrome P450 gene expression and enzymatic activities in rats and mice.

Sun G, Thai SF, Lambert GR, Wolf DC, Tully DB, Goetz AK, George MH, Grindstaff RD, Dix DJ, Nesnow S.

Toxicol Lett. 2006 Jun 20;164(1):44-53. Epub 2006 Jan 6.

PMID:
16406388
25.

Role of cell signaling in B[a]P-induced apoptosis: characterization of unspecific effects of cell signaling inhibitors and apoptotic effects of B[a]P metabolites.

Solhaug A, Øvrebø S, Mollerup S, Låg M, Schwarze PE, Nesnow S, Holme JA.

Chem Biol Interact. 2005 Jan 15;151(2):101-19.

PMID:
15698582
26.

Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene.

El-Bayoumy K, Sharma AK, Lin JM, Krzeminski J, Boyiri T, King LC, Lambert G, Padgett W, Nesnow S, Amin S.

Chem Res Toxicol. 2004 Dec;17(12):1591-9.

PMID:
15606134
27.

Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver.

Sun G, Thai SF, Tully DB, Lambert GR, Goetz AK, Wolf DC, Dix DJ, Nesnow S.

Toxicol Lett. 2005 Feb 15;155(2):277-87.

PMID:
15603923
28.

Identification and quantitation of benzo[a]pyrene-derived DNA adducts formed at low adduction level in mice lung tissue.

Banasiewicz M, Nelson G, Swank A, Grubor N, Ross J, Nesnow S, Köfeler H, Small GJ, Jankowiak R.

Anal Biochem. 2004 Nov 15;334(2):390-400.

PMID:
15494147
29.

Identification and characterization of novel stable deoxyguanosine and deoxyadenosine adducts of benzo[a]pyrene-7,8-quinone from reactions at physiological pH.

Balu N, Padgett WT, Lambert GR, Swank AE, Richard AM, Nesnow S.

Chem Res Toxicol. 2004 Jun;17(6):827-38.

PMID:
15206904
30.

DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species.

Nesnow S, Roop BC, Lambert G, Kadiiska M, Mason RP, Cullen WR, Mass MJ.

Chem Res Toxicol. 2002 Dec;15(12):1627-34.

PMID:
12482246
31.

Comparison of the genotoxic activities of the K-region dihydrodiol of benzo[a]pyrene with benzo[a]pyrene in mammalian cells: morphological cell transformation; DNA damage; and stable covalent DNA adducts.

Nesnow S, Davis C, Nelson GB, Lambert G, Padgett W, Pimentel M, Tennant AH, Kligerman AD, Ross JA.

Mutat Res. 2002 Nov 26;521(1-2):91-102.

PMID:
12438007
32.

Synthesis, in vitro metabolism, cell transformation, mutagenicity, and DNA adduction of dibenzo[c,mno]chrysene.

Desai D, Sharma AK, Lin JM, Krzeminski J, Pimentel M, El-Bayoumy K, Nesnow S, Amin S.

Chem Res Toxicol. 2002 Jul;15(7):964-71.

PMID:
12119008
33.

An evaluation of the mutagenicity, metabolism, and DNA adduct formation of 5-nitrobenzo[b]naphtho[2,1-d]thiophene.

King LC, Kohan MJ, Brooks L, Nelson GB, Ross JA, Allison J, Adams L, Desai D, Amin S, Padgett W, Lambert GR, Richard AM, Nesnow S.

Chem Res Toxicol. 2001 Jun;14(6):661-71.

PMID:
11409936
34.

Biotransformation of trans-4,5-dihydroxy-4,5-dihydrobenzo[a]pyrene to benzo[a]pyrene bis-diols and DNA adducts by induced rat liver microsomes.

Padgett WT, Davis C, Lambert G, Nelson GB, Ross JA, Yacopucci M, Nesnow S.

Chem Res Toxicol. 2000 Nov;13(11):1125-34.

PMID:
11087434
36.

Thirteenth Aspen Cancer Conference: workshop on mechanisms of toxicity and carcinogenesis.

Nesnow S, Cavanee W, Gilmer TM, Kaufman DG, Slaga TJ, Hohman R, Bishop JM, Poirier MC, Harris CC, Trump BF, Yuspa SH, Pfeifer AM, Sherman MI, Tennant R.

Mol Carcinog. 1999 Jun;25(2):99-106. No abstract available.

PMID:
10365911
37.

Quantitative analysis of alachlor protein adducts by gas chromatography-mass spectrometry.

Lambert GR, Padgett WT, George MH, Kitchin KT, Nesnow S.

Anal Biochem. 1999 Mar 15;268(2):289-96.

PMID:
10075819
38.

Polycyclic aromatic hydrocarbons: correlations between DNA adducts and ras oncogene mutations.

Ross JA, Nesnow S.

Mutat Res. 1999 Mar 8;424(1-2):155-66. Review.

PMID:
10064858
39.

Lung tumorigenic interactions in strain A/J mice of five environmental polycyclic aromatic hydrocarbons.

Nesnow S, Mass MJ, Ross JA, Galati AJ, Lambert GR, Gennings C, Carter WH Jr, Stoner GD.

Environ Health Perspect. 1998 Dec;106 Suppl 6:1337-46.

41.

Mechanistic relationships between DNA adducts, oncogene mutations, and lung tumorigenesis in strain A mice.

Nesnow S, Ross JA, Mass MJ, Stoner GD.

Exp Lung Res. 1998 Jul-Aug;24(4):395-405.

PMID:
9659573
42.

Twelfth Aspen Cancer Conference: mechanisms of toxicity and carcinogenesis.

Nesnow S, Harris CC, Trump BF, Mendelsohn ML, Dellarco V, Gilmer TM, Cavanee W, Tennant R.

Mol Carcinog. 1998 May;22(1):1-8. No abstract available.

PMID:
9609095
43.
44.

Dibenzo[a,l]pyrene-induced DNA adduction, tumorigenicity, and Ki-ras oncogene mutations in strain A/J mouse lung.

Prahalad AK, Ross JA, Nelson GB, Roop BC, King LC, Nesnow S, Mass MJ.

Carcinogenesis. 1997 Oct;18(10):1955-63.

PMID:
9364006
45.

Benzo[b]fluoranthene: tumorigenicity in strain A/J mouse lungs, DNA adducts and mutations in the Ki-ras oncogene.

Mass MJ, Abu-Shakra A, Roop BC, Nelson G, Galati AJ, Stoner GD, Nesnow S, Ross JA.

Carcinogenesis. 1996 Aug;17(8):1701-4.

PMID:
8761429
46.

Biotransformation of the cyclopenta-fused polycyclic aromatic hydrocarbon benz[j]aceanthrylene in isolated rat liver cell: identification of nine new metabolites.

Nyholm SH, Alexander J, Lundanes E, Frandsen H, Andersson R, Grivas S, Nesnow S, Holme JA.

Carcinogenesis. 1996 May;17(5):1111-20.

PMID:
8640921
48.

4-Ipomeanol and 2-aminoanthracene cytotoxicity in C3H/10T1/2 cells expressing rabbit cytochrome P450 4B1.

Smith PB, Tiano HF, Nesnow S, Boyd MR, Philpot RM, Langenbach R.

Biochem Pharmacol. 1995 Nov 9;50(10):1567-75.

PMID:
7503758
49.

Adenomas induced by polycyclic aromatic hydrocarbons in strain A/J mouse lung correlate with time-integrated DNA adduct levels.

Ross JA, Nelson GB, Wilson KH, Rabinowitz JR, Galati A, Stoner GD, Nesnow S, Mass MJ.

Cancer Res. 1995 Mar 1;55(5):1039-44.

50.

Synthesis and characterization of adducts of alachlor and 2-chloro-N-(2,6-diethylphenyl)acetamide with 2'-deoxyguanosine, thymidine, and their 3'-monophosphates.

Nesnow S, Agarwal SC, Padgett WT, Lambert GR, Boone P, Richard AM.

Chem Res Toxicol. 1995 Mar;8(2):209-17.

PMID:
7766803

Supplemental Content

Loading ...
Support Center