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Hyicin 4244, the first sactibiotic described in staphylococci, exhibits an anti-staphylococcal biofilm activity.

Duarte AFS, Ceotto-Vigoder H, Barrias ES, Souto-Padrón TCBS, Nes IF, Bastos MDCF.

Int J Antimicrob Agents. 2018 Mar;51(3):349-356. doi: 10.1016/j.ijantimicag.2017.06.025. Epub 2017 Jul 10.


Purification and characterization of two new cell-bound bioactive compounds produced by wild Lactococcus lactis strain.

Saraiva MAF, Brede DA, Nes IF, Baracat-Pereira MC, de Queiroz MV, de Moraes CA.

FEMS Microbiol Lett. 2017 Jul 3;364(12). doi: 10.1093/femsle/fnx130.


The Leaderless Bacteriocin Enterocin K1 Is Highly Potent against Enterococcus faecium: A Study on Structure, Target Spectrum and Receptor.

Ovchinnikov KV, Kristiansen PE, Straume D, Jensen MS, Aleksandrzak-Piekarczyk T, Nes IF, Diep DB.

Front Microbiol. 2017 May 3;8:774. doi: 10.3389/fmicb.2017.00774. eCollection 2017.


The prevalence of Listeria monocytogenes and Staphylococcus aureus and their virulence genes in bulk tank milk in Kosovo.

Mehmeti I, Bytyqi H, Muji S, Nes IF, Diep DB.

J Infect Dev Ctries. 2017 Mar 31;11(3):247-254. doi: 10.3855/jidc.8256.


Antimicrobial resistance levels amongst staphylococci isolated from clinical cases of bovine mastitis in Kosovo.

Mehmeti I, Behluli B, Mestani M, Ademi A, Nes IF, Diep DB.

J Infect Dev Ctries. 2016 Oct 31;10(10):1081-1087. doi: 10.3855/jidc.7912.


Draft Genome Sequence of the Bacteriocinogenic Strain Enterococcus faecalis DBH18, Isolated from Mallard Ducks (Anas platyrhynchos).

Arbulu S, Jimenez JJ, Borrero J, Sánchez J, Frantzen C, Herranz C, Nes IF, Cintas LM, Diep DB, Hernández PE.

Genome Announc. 2016 Jul 14;4(4). pii: e00663-16. doi: 10.1128/genomeA.00663-16.


Novel Group of Leaderless Multipeptide Bacteriocins from Gram-Positive Bacteria.

Ovchinnikov KV, Chi H, Mehmeti I, Holo H, Nes IF, Diep DB.

Appl Environ Microbiol. 2016 Aug 15;82(17):5216-24. doi: 10.1128/AEM.01094-16. Print 2016 Sep 1.


Efficient Inactivation of Multi-Antibiotics Resistant Nosocomial Enterococci by Purified Hiracin Bacteriocin.

Hassan M, Brede DA, Diep DB, Nes IF, Lotfipour F, Hojabri Z.

Adv Pharm Bull. 2015 Sep;5(3):393-401. doi: 10.15171/apb.2015.054. Epub 2015 Sep 19.


Cloning strategies for heterologous expression of the bacteriocin enterocin A by Lactobacillus sakei Lb790, Lb. plantarum NC8 and Lb. casei CECT475.

Jiménez JJ, Diep DB, Borrero J, Gútiez L, Arbulu S, Nes IF, Herranz C, Cintas LM, Hernández PE.

Microb Cell Fact. 2015 Oct 15;14:166. doi: 10.1186/s12934-015-0346-x.


Draft Genome Sequence of Lactobacillus kunkeei AR114 Isolated from Honey Bee Gut.

Porcellato D, Frantzen C, Rangberg A, Umu OC, Gabrielsen C, Nes IF, Amdam GV, Diep DB.

Genome Announc. 2015 Mar 19;3(2). pii: e00144-15. doi: 10.1128/genomeA.00144-15.


A genomic virulence reference map of Enterococcus faecalis reveals an important contribution of phage03-like elements in nosocomial genetic lineages to pathogenicity in a Caenorhabditis elegans infection model.

La Rosa SL, Snipen LG, Murray BE, Willems RJ, Gilmore MS, Diep DB, Nes IF, Brede DA.

Infect Immun. 2015 May;83(5):2156-67. doi: 10.1128/IAI.02801-14. Epub 2015 Mar 16.


The fsr Quorum-Sensing System and Cognate Gelatinase Orchestrate the Expression and Processing of Proprotein EF_1097 into the Mature Antimicrobial Peptide Enterocin O16.

Dundar H, Brede DA, La Rosa SL, El-Gendy AO, Diep DB, Nes IF.

J Bacteriol. 2015 Jul;197(13):2112-2121. doi: 10.1128/JB.02513-14. Epub 2015 Mar 2.


Circular bacteriocins: biosynthesis and mode of action.

Gabrielsen C, Brede DA, Nes IF, Diep DB.

Appl Environ Microbiol. 2014 Nov;80(22):6854-62. doi: 10.1128/AEM.02284-14. Epub 2014 Aug 29. Review.


Defining the structure and receptor binding domain of the leaderless bacteriocin LsbB.

Ovchinnikov KV, Kristiansen PE, Uzelac G, Topisirovic L, Kojic M, Nissen-Meyer J, Nes IF, Diep DB.

J Biol Chem. 2014 Aug 22;289(34):23838-45. doi: 10.1074/jbc.M114.579698. Epub 2014 Jul 3.


Sensitivity to the two-peptide bacteriocin lactococcin G is dependent on UppP, an enzyme involved in cell-wall synthesis.

Kjos M, Oppegård C, Diep DB, Nes IF, Veening JW, Nissen-Meyer J, Kristensen T.

Mol Microbiol. 2014 Jun;92(6):1177-87. doi: 10.1111/mmi.12632. Epub 2014 May 23.


Transcriptomic and functional analysis of NaCl-induced stress in Enterococcus faecalis.

Solheim M, La Rosa SL, Mathisen T, Snipen LG, Nes IF, Brede DA.

PLoS One. 2014 Apr 22;9(4):e94571. doi: 10.1371/journal.pone.0094571. eCollection 2014.


Transcriptional and Post Transcriptional Control of Enterococcal Gene Regulation.

DebRoy S, Gao P, Garsin DA, Harvey BR, Kos V, Nes IF, Solheim M.

In: Gilmore MS, Clewell DB, Ike Y, Shankar N, editors. Enterococci: From Commensals to Leading Causes of Drug Resistant Infection [Internet]. Boston: Massachusetts Eye and Ear Infirmary; 2014-.
2014 Feb 12.


Functional genetic analysis of the GarML gene cluster in Lactococcus garvieae DCC43 gives new insights into circular bacteriocin biosynthesis.

Gabrielsen C, Brede DA, Salehian Z, Nes IF, Diep DB.

J Bacteriol. 2014 Mar;196(5):911-9. doi: 10.1128/JB.01115-13. Epub 2013 Dec 13.


Immunity to the Staphylococcus aureus leaderless four-peptide bacteriocin aureocin A70 is conferred by AurI, an integral membrane protein.

Coelho ML, Coutinho BG, Cabral da Silva Santos O, Nes IF, Bastos Mdo C.

Res Microbiol. 2014 Jan;165(1):50-9. doi: 10.1016/j.resmic.2013.11.001. Epub 2013 Nov 14.


A Zn-dependent metallopeptidase is responsible for sensitivity to LsbB, a class II leaderless bacteriocin of Lactococcus lactis subsp. lactis BGMN1-5.

Uzelac G, Kojic M, Lozo J, Aleksandrzak-Piekarczyk T, Gabrielsen C, Kristensen T, Nes IF, Diep DB, Topisirovic L.

J Bacteriol. 2013 Dec;195(24):5614-21. doi: 10.1128/JB.00859-13. Epub 2013 Oct 11.


Potential applications of gut microbiota to control human physiology.

Umu OC, Oostindjer M, Pope PB, Svihus B, Egelandsdal B, Nes IF, Diep DB.

Antonie Van Leeuwenhoek. 2013 Nov;104(5):609-18. doi: 10.1007/s10482-013-0008-0. Epub 2013 Aug 23. Review.


Cloning, production, and functional expression of the bacteriocin sakacin A (SakA) and two SakA-derived chimeras in lactic acid bacteria (LAB) and the yeasts Pichia pastoris and Kluyveromyces lactis.

Jiménez JJ, Borrero J, Diep DB, Gútiez L, Nes IF, Herranz C, Cintas LM, Hernández PE.

J Ind Microbiol Biotechnol. 2013 Sep;40(9):977-93. doi: 10.1007/s10295-013-1302-6. Epub 2013 Jun 22.


Enterococcus faecalis grows on ascorbic acid.

Mehmeti I, Solheim M, Nes IF, Holo H.

Appl Environ Microbiol. 2013 Aug;79(15):4756-8. doi: 10.1128/AEM.00228-13. Epub 2013 May 24.


Genome sequence of the bacteriocin-producing strain Lactococcus garvieae DCC43.

Gabrielsen C, Brede DA, Hernández PE, Nes IF, Diep DB.

J Bacteriol. 2012 Dec;194(24):6976-7. doi: 10.1128/JB.01864-12.


Bacteriocin production, antibiotic susceptibility and prevalence of haemolytic and gelatinase activity in faecal lactic acid bacteria isolated from healthy Ethiopian infants.

Birri DJ, Brede DA, Tessema GT, Nes IF.

Microb Ecol. 2013 Feb;65(2):504-16. doi: 10.1007/s00248-012-0134-7. Epub 2012 Nov 27.


Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian KD, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJ, Rebuffat S, Ross RP, Sahl HG, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Süssmuth RD, Tagg JR, Tang GL, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA.

Nat Prod Rep. 2013 Jan;30(1):108-60. doi: 10.1039/c2np20085f. Review.


Novel Podoviridae family bacteriophage infecting Weissella cibaria isolated from Kimchi.

Kleppen HP, Holo H, Jeon SR, Nes IF, Yoon SS.

Appl Environ Microbiol. 2012 Oct;78(20):7299-308. Epub 2012 Aug 10.


Construction and application of a luxABCDE reporter system for real-time monitoring of Enterococcus faecalis gene expression and growth.

La Rosa SL, Diep DB, Nes IF, Brede DA.

Appl Environ Microbiol. 2012 Oct;78(19):7003-11. doi: 10.1128/AEM.02018-12. Epub 2012 Jul 27.


Characterization of a Leuconostoc bacteriophage infecting flavor producers of cheese starter cultures.

Kleppen HP, Nes IF, Holo H.

Appl Environ Microbiol. 2012 Sep;78(18):6769-72. doi: 10.1128/AEM.00562-12. Epub 2012 Jul 13.


Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance.

Hassan M, Kjos M, Nes IF, Diep DB, Lotfipour F.

J Appl Microbiol. 2012 Oct;113(4):723-36. doi: 10.1111/j.1365-2672.2012.05338.x. Epub 2012 Jun 8. Review.


Prevalence of bacteriocin activities and bacteriocin-encoding genes in enterococcal clinical isolates in Iran.

Hassan M, Diep DB, Javadzadeh Y, Dastmalchi S, Nes IF, Sharifi Y, Yari S, Farajnia S, Lotfipour F.

Can J Microbiol. 2012 Apr;58(4):359-68. doi: 10.1139/w11-136. Epub 2012 Mar 13.


The maltose ABC transporter in Lactococcus lactis facilitates high-level sensitivity to the circular bacteriocin garvicin ML.

Gabrielsen C, Brede DA, Hernández PE, Nes IF, Diep DB.

Antimicrob Agents Chemother. 2012 Jun;56(6):2908-15. doi: 10.1128/AAC.00314-12. Epub 2012 Mar 12.


Genes involved in immunity to and secretion of aureocin A53, an atypical class II bacteriocin produced by Staphylococcus aureus A53.

Nascimento Jdos S, Coelho ML, Ceotto H, Potter A, Fleming LR, Salehian Z, Nes IF, Bastos Mdo C.

J Bacteriol. 2012 Feb;194(4):875-83. doi: 10.1128/JB.06203-11. Epub 2011 Dec 9.


Salivaricin D, a novel intrinsically trypsin-resistant lantibiotic from Streptococcus salivarius 5M6c isolated from a healthy infant.

Birri DJ, Brede DA, Nes IF.

Appl Environ Microbiol. 2012 Jan;78(2):402-10. doi: 10.1128/AEM.06588-11. Epub 2011 Nov 18.


Growth rate-dependent control in Enterococcus faecalis: effects on the transcriptome and proteome, and strong regulation of lactate dehydrogenase.

Mehmeti I, Faergestad EM, Bekker M, Snipen L, Nes IF, Holo H.

Appl Environ Microbiol. 2012 Jan;78(1):170-6. doi: 10.1128/AEM.06604-11. Epub 2011 Oct 28.


Hyicin 3682, a bioactive peptide produced by Staphylococcus hyicus 3682 with potential applications for food preservation.

Fagundes PC, Ceotto H, Potter A, Vasconcelos de Paiva Brito MA, Brede D, Nes IF, Bastos Mdo C.

Res Microbiol. 2011 Dec;162(10):1052-9. doi: 10.1016/j.resmic.2011.10.002. Epub 2011 Oct 10.


Target recognition, resistance, immunity and genome mining of class II bacteriocins from Gram-positive bacteria.

Kjos M, Borrero J, Opsata M, Birri DJ, Holo H, Cintas LM, Snipen L, Hernández PE, Nes IF, Diep DB.

Microbiology. 2011 Dec;157(Pt 12):3256-67. doi: 10.1099/mic.0.052571-0. Epub 2011 Oct 6. Review.


Mechanisms of resistance to bacteriocins targeting the mannose phosphotransferase system.

Kjos M, Nes IF, Diep DB.

Appl Environ Microbiol. 2011 May;77(10):3335-42. doi: 10.1128/AEM.02602-10. Epub 2011 Mar 18.


Complete genome sequence of the commensal Enterococcus faecalis 62, isolated from a healthy Norwegian infant.

Brede DA, Snipen LG, Ussery DW, Nederbragt AJ, Nes IF.

J Bacteriol. 2011 May;193(9):2377-8. doi: 10.1128/JB.00183-11. Epub 2011 Mar 11.


Comparative genomics of Lactobacillus sakei with emphasis on strains from meat.

Nyquist OL, McLeod A, Brede DA, Snipen L, Aakra Å, Nes IF.

Mol Genet Genomics. 2011 Apr;285(4):297-311. doi: 10.1007/s00438-011-0608-1. Epub 2011 Mar 3.


Transcriptome, proteome, and metabolite analyses of a lactate dehydrogenase-negative mutant of Enterococcus faecalis V583.

Mehmeti I, Jönsson M, Fergestad EM, Mathiesen G, Nes IF, Holo H.

Appl Environ Microbiol. 2011 Apr;77(7):2406-13. doi: 10.1128/AEM.02485-10. Epub 2011 Feb 4.


Wide-Inhibitory Spectra Bacteriocins Produced by Lactobacillus gasseri K7.

Zorič Peternel M, Čanžek Majhenič A, Holo H, Nes IF, Salehian Z, Berlec A, Rogelj I.

Probiotics Antimicrob Proteins. 2010 Dec;2(4):233-40. doi: 10.1007/s12602-010-9044-5.


Characterization of garvicin ML, a novel circular bacteriocin produced by Lactococcus garvieae DCC43, isolated from mallard ducks (Anas platyrhynchos).

Borrero J, Brede DA, Skaugen M, Diep DB, Herranz C, Nes IF, Cintas LM, Hernández PE.

Appl Environ Microbiol. 2011 Jan;77(1):369-73. doi: 10.1128/AEM.01173-10. Epub 2010 Nov 5.


The unconventional antimicrobial peptides of the classical propionibacteria.

Faye T, Holo H, Langsrud T, Nes IF, Brede DA.

Appl Microbiol Biotechnol. 2011 Feb;89(3):549-54. doi: 10.1007/s00253-010-2967-7. Epub 2010 Oct 31. Review.


An extracellular loop of the mannose phosphotransferase system component IIC is responsible for specific targeting by class IIa bacteriocins.

Kjos M, Salehian Z, Nes IF, Diep DB.

J Bacteriol. 2010 Nov;192(22):5906-13. doi: 10.1128/JB.00777-10. Epub 2010 Sep 24.


Specific degradation of the mucus adhesion-promoting protein (MapA) of Lactobacillus reuteri to an antimicrobial peptide.

Bøhle LA, Brede DA, Diep DB, Holo H, Nes IF.

Appl Environ Microbiol. 2010 Nov;76(21):7306-9. doi: 10.1128/AEM.01423-10. Epub 2010 Sep 10.

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