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Critical Evaluation of Photo-cross-linking Parameters for the Implementation of Efficient DNA-Encoded Chemical Library Selections.

Sannino A, Gironda-Martínez A, Gorre ÉMD, Prati L, Piazzi J, Scheuermann J, Neri D, Donckele EJ, Samain F.

ACS Comb Sci. 2020 Mar 6. doi: 10.1021/acscombsci.0c00023. [Epub ahead of print]


A universal reporter cell line for bioactivity evaluation of engineered cytokine products.

Mock J, Pellegrino C, Neri D.

Sci Rep. 2020 Feb 24;10(1):3234. doi: 10.1038/s41598-020-60182-4.


Prevalence, Population Diversity and Antimicrobial Resistance of Campylobacter coli Isolated in Italian Swine at Slaughterhouse.

Di Donato G, Marotta F, Nuvoloni R, Zilli K, Neri D, Di Sabatino D, Calistri P, Di Giannatale E.

Microorganisms. 2020 Feb 7;8(2). pii: E222. doi: 10.3390/microorganisms8020222.


Feeding practices of low birth weight Brazilian infants and associated factors.

Ortelan N, Neri DA, Benicio MHD.

Rev Saude Publica. 2020 Jan 31;54:14. doi: 10.11606/s1518-8787.2020054001028. eCollection 2020. English, Portuguese.


Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection.

Kräutler NJ, Yermanos A, Pedrioli A, Welten SPM, Lorgé D, Greczmiel U, Bartsch I, Scheuermann J, Kiefer JD, Eyer K, Menzel U, Greiff V, Neri D, Stadler T, Reddy ST, Oxenius A.

Cell Rep. 2020 Jan 28;30(4):997-1012.e6. doi: 10.1016/j.celrep.2019.12.088.


A novel human monoclonal antibody specific to the A33 glycoprotein recognizes colorectal cancer and inhibits metastasis.

Murer P, Plüss L, Neri D.

MAbs. 2020 Jan-Dec;12(1):1714371. doi: 10.1080/19420862.2020.1714371.


Thermotolerant Campylobacter spp. in chicken and bovine meat in Italy: Prevalence, level of contamination and molecular characterization of isolates.

Di Giannatale E, Calistri P, Di Donato G, Decastelli L, Goffredo E, Adriano D, Mancini ME, Galleggiante A, Neri D, Antoci S, Marfoglia C, Marotta F, Nuvoloni R, Migliorati G.

PLoS One. 2019 Dec 6;14(12):e0225957. doi: 10.1371/journal.pone.0225957. eCollection 2019.


Targeted enhancement of the therapeutic window of L19-TNF by transient and selective inhibition of RIPK1-signaling cascade.

Dakhel S, Ongaro T, Gouyou B, Matasci M, Villa A, Neri D, Cazzamalli S.

Oncotarget. 2019 Nov 19;10(62):6678-6690. doi: 10.18632/oncotarget.27320. eCollection 2019 Nov 19.


A Novel Fully-Human Potency-Matched Dual Cytokine-Antibody Fusion Protein Targets Carbonic Anhydrase IX in Renal Cell Carcinomas.

De Luca R, Gouyou B, Ongaro T, Villa A, Ziffels B, Sannino A, Buttinoni G, Galeazzi S, Mazzacuva M, Neri D.

Front Oncol. 2019 Nov 13;9:1228. doi: 10.3389/fonc.2019.01228. eCollection 2019.


Comparative evaluation of bolus and fractionated administration modalities for two antibody-cytokine fusions in immunocompetent tumor-bearing mice.

Puca E, De Luca R, Seehusen F, Rodriguez JMM, Neri D.

J Control Release. 2020 Jan 10;317:282-290. doi: 10.1016/j.jconrel.2019.11.036. Epub 2019 Nov 29.


DNA-Compatible Diazo-Transfer Reaction in Aqueous Media Suitable for DNA-Encoded Chemical Library Synthesis.

Gironda-Martínez A, Neri D, Samain F, Donckele EJ.

Org Lett. 2019 Dec 6;21(23):9555-9558. doi: 10.1021/acs.orglett.9b03726. Epub 2019 Nov 20.


Correction: Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry.

Marotta F, Garofolo G, Di Marcantonio L, Di Serafino G, Neri D, Romantini R, Sacchini L, Alessiani A, Di Donato G, Nuvoloni R, Janowicz A, Di Giannatale E.

PLoS One. 2019 Nov 7;14(11):e0225231. doi: 10.1371/journal.pone.0225231. eCollection 2019.


Automated and enhanced extraction of a small molecule-drug conjugate using an enzyme-inhibitor interaction based SPME tool followed by direct analysis by ESI-MS.

Ghiasikhou S, Cazzamalli S, Scheuermann J, Neri D, Zenobi R.

Anal Bioanal Chem. 2019 Nov;411(28):7387-7398. doi: 10.1007/s00216-019-02165-7. Epub 2019 Oct 30.


Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry.

Marotta F, Garofolo G, di Marcantonio L, Di Serafino G, Neri D, Romantini R, Sacchini L, Alessiani A, Di Donato G, Nuvoloni R, Janowicz A, Di Giannatale E.

PLoS One. 2019 Oct 11;14(10):e0223804. doi: 10.1371/journal.pone.0223804. eCollection 2019. Erratum in: PLoS One. 2019 Nov 7;14(11):e0225231.


A phase II study of the L19IL2 immunocytokine in combination with dacarbazine in advanced metastatic melanoma patients.

Weide B, Eigentler T, Catania C, Ascierto PA, Cascinu S, Becker JC, Hauschild A, Romanini A, Danielli R, Dummer R, Trefzer U, Elia G, Neri D, Garbe C.

Cancer Immunol Immunother. 2019 Sep;68(9):1547-1559. doi: 10.1007/s00262-019-02383-z. Epub 2019 Sep 3.


Erratum: In Vivo Antitumor Activity of a Novel Acetazolamide-Cryptophycin Conjugate for the Treatment of Renal Cell Carcinoma.

Cazzamalli S, Figueras E, Pethő L, Borbély A, Steinkühler C, Neri D, Sewald N.

ACS Omega. 2018 Dec 5;3(12):16743. doi: 10.1021/acsomega.8b03183. eCollection 2018 Dec 31.


The antibody-based delivery of interleukin-12 to solid tumors boosts NK and CD8+ T cell activity and synergizes with immune checkpoint inhibitors.

Puca E, Probst P, Stringhini M, Murer P, Pellegrini G, Cazzamalli S, Hutmacher C, Gouyou B, Wulhfard S, Matasci M, Villa A, Neri D.

Int J Cancer. 2020 May 1;146(9):2518-2530. doi: 10.1002/ijc.32603. Epub 2019 Aug 28.


Videolaparoscopic microwave ablation in patients with HCC at a European high-volume center: Results of 815 procedures.

Cillo U, Bertacco A, Fasolo E, Carandina R, Vitale A, Zanus G, Gringeri E, D'Amico F, Bassi D, Neri D, Dadduzio V, Farinati F, Aliberti C.

J Surg Oncol. 2019 Nov;120(6):956-965. doi: 10.1002/jso.25651. Epub 2019 Aug 1.


Consumption of ultra-processed foods and its association with added sugar content in the diets of US children, NHANES 2009-2014.

Neri D, Martinez-Steele E, Monteiro CA, Levy RB.

Pediatr Obes. 2019 Dec;14(12):e12563. doi: 10.1111/ijpo.12563. Epub 2019 Jul 30.


Design and characterisation of a novel interleukin-15 receptor alpha fusion protein and analysis of interleukin-15 complexation.

Schmid AS, Neri D.

PLoS One. 2019 Jul 26;14(7):e0219313. doi: 10.1371/journal.pone.0219313. eCollection 2019.


Development of a novel fully-human anti-CD123 antibody to target acute myeloid leukemia.

Hutmacher C, Volta L, Rinaldi F, Murer P, Myburgh R, Manz MG, Neri D.

Leuk Res. 2019 Sep;84:106178. doi: 10.1016/j.leukres.2019.106178. Epub 2019 Jun 27.


Antibody-Based Delivery of Cytokine Payloads to Carbonic Anhydrase IX Leads to Cancer Cures in Immunocompetent Tumor-Bearing Mice.

Ziffels B, Stringhini M, Probst P, Fugmann T, Sturm T, Neri D.

Mol Cancer Ther. 2019 Sep;18(9):1544-1554. doi: 10.1158/1535-7163.MCT-18-1301. Epub 2019 Jun 18.


Research on food-related chronic diseases in Latin America and the Caribbean: Are we building the evidence for gender-equitable approaches?

Ludwick T, Neri D.

Rev Panam Salud Publica. 2019 Jun 7;43:e43. doi: 10.26633/RPSP.2019.43. eCollection 2019.


Dietary share of ultra-processed foods and metabolic syndrome in the US adult population.

Martínez Steele E, Juul F, Neri D, Rauber F, Monteiro CA.

Prev Med. 2019 Aug;125:40-48. doi: 10.1016/j.ypmed.2019.05.004. Epub 2019 May 9.


ALCAM Mediates DC Migration Through Afferent Lymphatics and Promotes Allospecific Immune Reactions.

Willrodt AH, Salabarria AC, Schineis P, Ignatova D, Hunter MC, Vranova M, Golding-Ochsenbein AM, Sigmund E, Romagna A, Strassberger V, Fabbi M, Ferrini S, Cursiefen C, Neri D, Guenova E, Bock F, Halin C.

Front Immunol. 2019 Apr 12;10:759. doi: 10.3389/fimmu.2019.00759. eCollection 2019.


Third Trimester Vitamin D Status Is Associated With Birth Outcomes and Linear Growth of HIV-Exposed Uninfected Infants in the United States.

Sudfeld CR, Jacobson DL, Rueda NM, Neri D, Mendez AJ, Butler L, Siminski S, Hendricks KM, Mellins CA, Duggan CP, Miller TL; Pediatric HIV/AIDS Cohort Study.

J Acquir Immune Defic Syndr. 2019 Jul 1;81(3):336-344. doi: 10.1097/QAI.0000000000002041.


Antibody-cytokine fusion proteins: A novel class of biopharmaceuticals for the therapy of cancer and of chronic inflammation.

Murer P, Neri D.

N Biotechnol. 2019 Sep 25;52:42-53. doi: 10.1016/j.nbt.2019.04.002. Epub 2019 Apr 13. Review.


Association between watching TV whilst eating and children's consumption of ultraprocessed foods in United Kingdom.

Martines RM, Machado PP, Neri DA, Levy RB, Rauber F.

Matern Child Nutr. 2019 Oct;15(4):e12819. doi: 10.1111/mcn.12819. Epub 2019 May 23.


A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes.

Yuen LH, Dana S, Liu Y, Bloom SI, Thorsell AG, Neri D, Donato AJ, Kireev D, Schüler H, Franzini RM.

J Am Chem Soc. 2019 Apr 3;141(13):5169-5181. doi: 10.1021/jacs.8b08039. Epub 2019 Mar 19.


A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia.

Akkapeddi P, Fragoso R, Hixon JA, Ramalho AS, Oliveira ML, Carvalho T, Gloger A, Matasci M, Corzana F, Durum SK, Neri D, Bernardes GJL, Barata JT.

Leukemia. 2019 Sep;33(9):2155-2168. doi: 10.1038/s41375-019-0434-8. Epub 2019 Mar 8.


Antibody-Cytokine Fusions: Versatile Products for the Modulation of Anticancer Immunity.

Neri D.

Cancer Immunol Res. 2019 Mar;7(3):348-354. doi: 10.1158/2326-6066.CIR-18-0622. Review.


Advances in antibody engineering for rheumatic diseases.

Schmid AS, Neri D.

Nat Rev Rheumatol. 2019 Apr;15(4):197-207. doi: 10.1038/s41584-019-0188-8. Review.


Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Activation of NK and CD8+ T Cells.

Hutmacher C, Gonzalo Núñez N, Liuzzi AR, Becher B, Neri D.

Cancer Immunol Res. 2019 Apr;7(4):572-583. doi: 10.1158/2326-6066.CIR-18-0566. Epub 2019 Feb 19.


Ultra-processed foods: what they are and how to identify them.

Monteiro CA, Cannon G, Levy RB, Moubarac JC, Louzada ML, Rauber F, Khandpur N, Cediel G, Neri D, Martinez-Steele E, Baraldi LG, Jaime PC.

Public Health Nutr. 2019 Apr;22(5):936-941. doi: 10.1017/S1368980018003762. Epub 2019 Feb 12.


A novel anti-cancer L19-interleukin-12 fusion protein with an optimized peptide linker efficiently localizes in vivo at the site of tumors.

Ongaro T, Matasci M, Cazzamalli S, Gouyou B, De Luca R, Neri D, Villa A.

J Biotechnol. 2019 Feb 10;291:17-25. doi: 10.1016/j.jbiotec.2018.12.004. Epub 2018 Dec 23.


Targeted delivery of calreticulin to ED-A fibronectin leads to tumor-growth retardation.

Ziffels B, Grötsch A, Al-Bayati L, Neri D.

J Biotechnol. 2019 Jan 20;290:53-58. doi: 10.1016/j.jbiotec.2018.12.007. Epub 2018 Dec 20.


F8-IL10: A New Potential Antirheumatic Drug Evaluated by a PET-Guided Translational Approach.

Bruijnen STG, Chandrupatla DMSH, Giovanonni L, Neri D, Vugts DJ, Huisman MC, Hoekstra OS, Musters RJP, Lammertsma AA, van Dongen GAMS, Jansen G, Molthoff CFM, van der Laken CJ.

Mol Pharm. 2019 Jan 7;16(1):273-281. doi: 10.1021/acs.molpharmaceut.8b00982. Epub 2018 Dec 24.


Quantitative Assessment of Affinity Selection Performance by Using DNA-Encoded Chemical Libraries.

Sannino A, Gabriele E, Bigatti M, Mulatto S, Piazzi J, Scheuermann J, Neri D, Donckele EJ, Samain F.

Chembiochem. 2019 Apr 1;20(7):955-962. doi: 10.1002/cbic.201800766. Epub 2019 Feb 20.


Targeted Delivery of TNF Potentiates the Antibody-Dependent Cell-Mediated Cytotoxicity of an Anti-Melanoma Immunoglobulin.

Murer P, Kiefer JD, Plüss L, Matasci M, Blümich SL, Stringhini M, Neri D.

J Invest Dermatol. 2019 Jun;139(6):1339-1348. doi: 10.1016/j.jid.2018.11.028. Epub 2018 Dec 10.


In Vivo Antitumor Activity of a Novel Acetazolamide-Cryptophycin Conjugate for the Treatment of Renal Cell Carcinomas.

Cazzamalli S, Figueras E, Pethő L, Borbély A, Steinkühler C, Neri D, Sewald N.

ACS Omega. 2018 Nov 30;3(11):14726-14731. doi: 10.1021/acsomega.8b02350. Epub 2018 Nov 2. Erratum in: ACS Omega. 2018 Dec 05;3(12):16743.


Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation.

Schwager S, Renner S, Hemmerle T, Karaman S, Proulx ST, Fetz R, Golding-Ochsenbein AM, Probst P, Halin C, Neri D, Detmar M.

JCI Insight. 2018 Dec 6;3(23). pii: 124850. doi: 10.1172/jci.insight.124850.


Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues.

Dal Corso A, Catalano M, Schmid A, Scheuermann J, Neri D.

Angew Chem Int Ed Engl. 2018 Dec 21;57(52):17178-17182. doi: 10.1002/anie.201811650. Epub 2018 Nov 26.



Lourenço ASN, Neri DA, Konstantyner T, Palma D, Oliveira FLC.

Rev Paul Pediatr. 2018 Jul-Sep;36(3):292-300. doi: 10.1590/1984-0462/;2018;36;3;00012. Portuguese, English.


Antibody-based Delivery of TNF to the Tumor Neovasculature Potentiates the Therapeutic Activity of a Peptide Anticancer Vaccine.

Probst P, Stringhini M, Ritz D, Fugmann T, Neri D.

Clin Cancer Res. 2019 Jan 15;25(2):698-709. doi: 10.1158/1078-0432.CCR-18-1728. Epub 2018 Oct 16.


Staphylococcal Enterotoxins Dose-Dependently Modulate the Generation of Myeloid-Derived Suppressor Cells.

Stoll H, Ost M, Singh A, Mehling R, Neri D, Schäfer I, Velic A, Macek B, Kretschmer D, Weidenmaier C, Hector A, Handgretinger R, Götz F, Peschel A, Hartl D, Rieber N.

Front Cell Infect Microbiol. 2018 Sep 13;8:321. doi: 10.3389/fcimb.2018.00321. eCollection 2018.


Antibody-cytokine fusion proteins: Biopharmaceuticals with immunomodulatory properties for cancer therapy.

Hutmacher C, Neri D.

Adv Drug Deliv Rev. 2019 Feb 15;141:67-91. doi: 10.1016/j.addr.2018.09.002. Epub 2018 Sep 7. Review.


Human T cells modulate myeloid-derived suppressor cells through a TNF-α-mediated mechanism.

Bauswein M, Singh A, Ralhan A, Neri D, Fuchs K, Blanz KD, Schäfer I, Hector A, Handgretinger R, Hartl D, Rieber N.

Immunol Lett. 2018 Oct;202:31-37. doi: 10.1016/j.imlet.2018.07.010. Epub 2018 Aug 1.


The Tagging Procedure of Visible Implant Elastomers Influences Zebrafish Individual and Social Behavior.

Ruberto T, Clément RJG, Spinello C, Neri D, Macrì S, Porfiri M.

Zebrafish. 2018 Oct;15(5):433-444. doi: 10.1089/zeb.2018.1616. Epub 2018 Aug 2.


A severe outbreak of listeriosis in central Italy with a rare pulsotype associated with processed pork products.

Duranti A, Sabbatucci M, Blasi G, Acciari VA, Ancora M, Bella A, Busani L, Centorame P, Cammà C, Conti F, De Medici D, Di Domenico M, Di Marzio V, Filippini G, Fiore A, Fisichella S, Gattuso A, Gianfranceschi M, Graziani C, Guidi F, Marcacci M, Marfoglia C, Neri D, Orsini M, Ottaviani D, Petruzzelli A, Pezzotti P, Rizzo C, Ruolo A, Scavia G, Scuota S, Tagliavento G, Tibaldi A, Tonucci F, Torresi M, Migliorati G, Pomilio F.

J Med Microbiol. 2018 Sep;67(9):1351-1360. doi: 10.1099/jmm.0.000785. Epub 2018 Jul 19.


A novel dual-cytokine-antibody fusion protein for the treatment of CD38-positive malignancies.

De Luca R, Kachel P, Kropivsek K, Snijder B, Manz MG, Neri D.

Protein Eng Des Sel. 2018 May 1;31(5):173-179. doi: 10.1093/protein/gzy015.

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