Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 171


The Role of the Voltage-Gated Potassium Channel Proteins Kv8.2 and Kv2.1 in Vision and Retinal Disease: Insights from the Study of Mouse Gene Knock-Out Mutations.

Hart NS, Mountford JK, Voigt V, Fuller-Carter P, Barth M, Nerbonne JM, Hunt DM, Carvalho LS.

eNeuro. 2019 Feb 25;6(1). pii: ENEURO.0032-19.2019. doi: 10.1523/ENEURO.0032-19.2019. eCollection 2019 Jan-Feb.


Regional differences in the expression of tetrodotoxin-sensitive inward Ca2+ and outward Cs+/K+ currents in mouse and human ventricles.

Wang W, Mellor RL, Nerbonne JM, Balke CW.

Channels (Austin). 2019 Dec;13(1):72-87. doi: 10.1080/19336950.2019.1568146.


Regional Differences in mRNA and lncRNA Expression Profiles in Non-Failing Human Atria and Ventricles.

Johnson EK, Matkovich SJ, Nerbonne JM.

Sci Rep. 2018 Sep 17;8(1):13919. doi: 10.1038/s41598-018-32154-2.


Circulating long noncoding RNA DKFZP434I0714 predicts adverse cardiovascular outcomes in patients with end-stage renal disease.

Lai CF, Chen YT, Gu J, Nerbonne JM, Lin CH, Yang KC.

Int J Cardiol. 2019 Feb 15;277:212-219. doi: 10.1016/j.ijcard.2018.08.013. Epub 2018 Aug 7.


Voltage-gated sodium currents in cerebellar Purkinje neurons: functional and molecular diversity.

Ransdell JL, Nerbonne JM.

Cell Mol Life Sci. 2018 Oct;75(19):3495-3505. doi: 10.1007/s00018-018-2868-y. Epub 2018 Jul 7. Review.


Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation.

Shih YC, Chen CL, Zhang Y, Mellor RL, Kanter EM, Fang Y, Wang HC, Hung CT, Nong JY, Chen HJ, Lee TH, Tseng YS, Chen CN, Wu CC, Lin SL, Yamada KA, Nerbonne JM, Yang KC.

Circ Res. 2018 Apr 13;122(8):1052-1068. doi: 10.1161/CIRCRESAHA.117.312130. Epub 2018 Mar 13.


Differential Expression and Remodeling of Transient Outward Potassium Currents in Human Left Ventricles.

Johnson EK, Springer SJ, Wang W, Dranoff EJ, Zhang Y, Kanter EM, Yamada KA, Nerbonne JM.

Circ Arrhythm Electrophysiol. 2018 Jan;11(1):e005914. doi: 10.1161/CIRCEP.117.005914.


C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation.

Burel S, Coyan FC, Lorenzini M, Meyer MR, Lichti CF, Brown JH, Loussouarn G, Charpentier F, Nerbonne JM, Townsend RR, Maier LS, Marionneau C.

J Biol Chem. 2017 Oct 20;292(42):17431-17448. doi: 10.1074/jbc.M117.787788. Epub 2017 Sep 7.


Loss of Navβ4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance.

Ransdell JL, Dranoff E, Lau B, Lo WL, Donermeyer DL, Allen PM, Nerbonne JM.

Cell Rep. 2017 Aug 8;20(6):1502. doi: 10.1016/j.celrep.2017.07.072. No abstract available.


Mechanisms of noncovalent β subunit regulation of NaV channel gating.

Zhu W, Voelker TL, Varga Z, Schubert AR, Nerbonne JM, Silva JR.

J Gen Physiol. 2017 Jul 18. pii: jgp.201711802. doi: 10.1085/jgp.201711802. [Epub ahead of print]


Acute Knockdown of Kv4.1 Regulates Repetitive Firing Rates and Clock Gene Expression in the Suprachiasmatic Nucleus and Daily Rhythms in Locomotor Behavior.

Hermanstyne TO, Granados-Fuentes D, Mellor RL, Herzog ED, Nerbonne JM.

eNeuro. 2017 May 23;4(3). pii: ENEURO.0377-16.2017. doi: 10.1523/ENEURO.0377-16.2017. eCollection 2017 May-Jun.


Loss of Navβ4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance.

Ransdell JL, Dranoff E, Lau B, Lo WL, Donermeyer DL, Allen PM, Nerbonne JM.

Cell Rep. 2017 Apr 18;19(3):532-544. doi: 10.1016/j.celrep.2017.03.068. Erratum in: Cell Rep. 2017 Aug 8;20(6):1502.


Early remodeling of repolarizing K+ currents in the αMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

Hueneke R, Adenwala A, Mellor RL, Seidman JG, Seidman CE, Nerbonne JM.

J Mol Cell Cardiol. 2017 Feb;103:93-101. doi: 10.1016/j.yjmcc.2017.01.006. Epub 2017 Jan 13.


Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics.

Chiamvimonvat N, Chen-Izu Y, Clancy CE, Deschenes I, Dobrev D, Heijman J, Izu L, Qu Z, Ripplinger CM, Vandenberg JI, Weiss JN, Koren G, Banyasz T, Grandi E, Sanguinetti MC, Bers DM, Nerbonne JM.

J Physiol. 2017 Apr 1;595(7):2229-2252. doi: 10.1113/JP272883. Epub 2017 Jan 5. Review.


Training the Next Generation of Translational Cardiovascular Investigators: Is the Pipeline Half Full or Half Empty?

Nerbonne JM, Mann DL.

JACC Basic Transl Sci. 2016 Oct 31;1(6):554-556. doi: 10.1016/j.jacbts.2016.08.003. eCollection 2016 Oct. No abstract available.


Notch-Mediated Epigenetic Regulation of Voltage-Gated Potassium Currents.

Khandekar A, Springer S, Wang W, Hicks S, Weinheimer C, Diaz-Trelles R, Nerbonne JM, Rentschler S.

Circ Res. 2016 Dec 9;119(12):1324-1338. doi: 10.1161/CIRCRESAHA.116.309877. Epub 2016 Oct 3.


Molecular Basis of Functional Myocardial Potassium Channel Diversity.

Nerbonne JM.

Card Electrophysiol Clin. 2016 Jun;8(2):257-73. doi: 10.1016/j.ccep.2016.01.001. Epub 2016 Mar 24. Review.


Proteomic analysis of native cerebellar iFGF14 complexes.

Bosch MK, Nerbonne JM, Townsend RR, Miyazaki H, Nukina N, Ornitz DM, Marionneau C.

Channels (Austin). 2016 Jul 3;10(4):297-312. doi: 10.1080/19336950.2016.1153203. Epub 2016 Feb 18.


Cardiac Mechano-Gated Ion Channels and Arrhythmias.

Peyronnet R, Nerbonne JM, Kohl P.

Circ Res. 2016 Jan 22;118(2):311-29. doi: 10.1161/CIRCRESAHA.115.305043. Review.


Distinct Firing Properties of Vasoactive Intestinal Peptide-Expressing Neurons in the Suprachiasmatic Nucleus.

Hermanstyne TO, Simms CL, Carrasquillo Y, Herzog ED, Nerbonne JM.

J Biol Rhythms. 2016 Feb;31(1):57-67. doi: 10.1177/0748730415619745. Epub 2015 Dec 27.


Mechanisms contributing to myocardial potassium channel diversity, regulation and remodeling.

Yang KC, Nerbonne JM.

Trends Cardiovasc Med. 2016 Apr;26(3):209-18. doi: 10.1016/j.tcm.2015.07.002. Epub 2015 Jul 17. Review.


IA Channels Encoded by Kv1.4 and Kv4.2 Regulate Circadian Period of PER2 Expression in the Suprachiasmatic Nucleus.

Granados-Fuentes D, Hermanstyne TO, Carrasquillo Y, Nerbonne JM, Herzog ED.

J Biol Rhythms. 2015 Oct;30(5):396-407. doi: 10.1177/0748730415593377. Epub 2015 Jul 6.


Intracellular FGF14 (iFGF14) Is Required for Spontaneous and Evoked Firing in Cerebellar Purkinje Neurons and for Motor Coordination and Balance.

Bosch MK, Carrasquillo Y, Ransdell JL, Kanakamedala A, Ornitz DM, Nerbonne JM.

J Neurosci. 2015 Apr 29;35(17):6752-69. doi: 10.1523/JNEUROSCI.2663-14.2015.


Generation of human striatal neurons by microRNA-dependent direct conversion of fibroblasts.

Victor MB, Richner M, Hermanstyne TO, Ransdell JL, Sobieski C, Deng PY, Klyachko VA, Nerbonne JM, Yoo AS.

Neuron. 2014 Oct 22;84(2):311-23. doi: 10.1016/j.neuron.2014.10.016. Epub 2014 Oct 22.


Dual transgene expression in murine cerebellar Purkinje neurons by viral transduction in vivo.

Bosch MK, Nerbonne JM, Ornitz DM.

PLoS One. 2014 Aug 5;9(8):e104062. doi: 10.1371/journal.pone.0104062. eCollection 2014.


Characterization of SEMA3A-encoded semaphorin as a naturally occurring Kv4.3 protein inhibitor and its contribution to Brugada syndrome.

Boczek NJ, Ye D, Johnson EK, Wang W, Crotti L, Tester DJ, Dagradi F, Mizusawa Y, Torchio M, Alders M, Giudicessi JR, Wilde AA, Schwartz PJ, Nerbonne JM, Ackerman MJ.

Circ Res. 2014 Aug 1;115(4):460-9. doi: 10.1161/CIRCRESAHA.115.303657. Epub 2014 Jun 24.


Mouse models of arrhythmogenic cardiovascular disease: challenges and opportunities.

Nerbonne JM.

Curr Opin Pharmacol. 2014 Apr;15:107-14. doi: 10.1016/j.coph.2014.02.003. Epub 2014 Mar 13. Review.


Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.

Speca DJ, Ogata G, Mandikian D, Bishop HI, Wiler SW, Eum K, Wenzel HJ, Doisy ET, Matt L, Campi KL, Golub MS, Nerbonne JM, Hell JW, Trainor BC, Sack JT, Schwartzkroin PA, Trimmer JS.

Genes Brain Behav. 2014 Apr;13(4):394-408. doi: 10.1111/gbb.12120. Epub 2014 Mar 7.


Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support.

Yang KC, Yamada KA, Patel AY, Topkara VK, George I, Cheema FH, Ewald GA, Mann DL, Nerbonne JM.

Circulation. 2014 Mar 4;129(9):1009-21. doi: 10.1161/CIRCULATIONAHA.113.003863. Epub 2014 Jan 15.


A fully implantable pacemaker for the mouse: from battery to wireless power.

Laughner JI, Marrus SB, Zellmer ER, Weinheimer CJ, MacEwan MR, Cui SX, Nerbonne JM, Efimov IR.

PLoS One. 2013 Oct 23;8(10):e76291. doi: 10.1371/journal.pone.0076291. eCollection 2013.


Distinct balance of excitation and inhibition in an interareal feedforward and feedback circuit of mouse visual cortex.

Yang W, Carrasquillo Y, Hooks BM, Nerbonne JM, Burkhalter A.

J Neurosci. 2013 Oct 30;33(44):17373-84. doi: 10.1523/JNEUROSCI.2515-13.2013.


IA channels: diverse regulatory mechanisms.

Carrasquillo Y, Nerbonne JM.

Neuroscientist. 2014 Apr;20(2):104-11. doi: 10.1177/1073858413504003. Epub 2013 Oct 8. Review.


FGF14 localization and organization of the axon initial segment.

Xiao M, Bosch MK, Nerbonne JM, Ornitz DM.

Mol Cell Neurosci. 2013 Sep;56:393-403. doi: 10.1016/j.mcn.2013.07.008. Epub 2013 Jul 26.


How to build an integrated biobank: the Washington University Translational Cardiovascular Biobank & Repository experience.

Yamada KA, Patel AY, Ewald GA, Whitehead DS, Pasque MK, Silvestry SC, Janks DL, Mann DL, Nerbonne JM.

Clin Transl Sci. 2013 Jun;6(3):226-31. doi: 10.1111/cts.12032. Epub 2013 Apr 18.


Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents.

Foeger NC, Wang W, Mellor RL, Nerbonne JM.

J Physiol. 2013 Sep 1;591(17):4149-66. doi: 10.1113/jphysiol.2013.255836. Epub 2013 May 27.


Gender differences in electrophysiological gene expression in failing and non-failing human hearts.

Ambrosi CM, Yamada KA, Nerbonne JM, Efimov IR.

PLoS One. 2013;8(1):e54635. doi: 10.1371/journal.pone.0054635. Epub 2013 Jan 23.


Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites.

Marionneau C, Lichti CF, Lindenbaum P, Charpentier F, Nerbonne JM, Townsend RR, Mérot J.

J Proteome Res. 2012 Dec 7;11(12):5994-6007. doi: 10.1021/pr300702c. Epub 2012 Nov 9.


CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting.

Pietka TA, Sulkin MS, Kuda O, Wang W, Zhou D, Yamada KA, Yang K, Su X, Gross RW, Nerbonne JM, Efimov IR, Abumrad NA.

J Biol Chem. 2012 Nov 9;287(46):38901-12. doi: 10.1074/jbc.M112.413609. Epub 2012 Sep 27.


Kv4.2 potassium channels segregate to extrasynaptic domains and influence intrasynaptic NMDA receptor NR2B subunit expression.

Kaufmann WA, Matsui K, Jeromin A, Nerbonne JM, Ferraguti F.

Brain Struct Funct. 2013 Sep;218(5):1115-32. doi: 10.1007/s00429-012-0450-1. Epub 2012 Aug 30.


Exercise training and PI3Kα-induced electrical remodeling is independent of cellular hypertrophy and Akt signaling.

Yang KC, Tseng YT, Nerbonne JM.

J Mol Cell Cardiol. 2012 Oct;53(4):532-41. doi: 10.1016/j.yjmcc.2012.07.004. Epub 2012 Jul 21.


I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity.

Granados-Fuentes D, Norris AJ, Carrasquillo Y, Nerbonne JM, Herzog ED.

J Neurosci. 2012 Jul 18;32(29):10045-52. doi: 10.1523/JNEUROSCI.0174-12.2012.


Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk.

Chen Y, Csordás G, Jowdy C, Schneider TG, Csordás N, Wang W, Liu Y, Kohlhaas M, Meiser M, Bergem S, Nerbonne JM, Dorn GW 2nd, Maack C.

Circ Res. 2012 Sep 14;111(7):863-75. doi: 10.1161/CIRCRESAHA.112.266585. Epub 2012 Jul 9.


A-type K+ channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons.

Carrasquillo Y, Burkhalter A, Nerbonne JM.

J Physiol. 2012 Aug 15;590(16):3877-90. doi: 10.1113/jphysiol.2012.229013. Epub 2012 May 21.


Combined deep microRNA and mRNA sequencing identifies protective transcriptomal signature of enhanced PI3Kα signaling in cardiac hypertrophy.

Yang KC, Ku YC, Lovett M, Nerbonne JM.

J Mol Cell Cardiol. 2012 Jul;53(1):101-12. doi: 10.1016/j.yjmcc.2012.04.012. Epub 2012 May 11.


The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.

Marionneau C, Carrasquillo Y, Norris AJ, Townsend RR, Isom LL, Link AJ, Nerbonne JM.

J Neurosci. 2012 Apr 25;32(17):5716-27. doi: 10.1523/JNEUROSCI.6450-11.2012.


ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling.

Liu F, Kang I, Park C, Chang LW, Wang W, Lee D, Lim DS, Vittet D, Nerbonne JM, Choi K.

Blood. 2012 Apr 5;119(14):3295-305. doi: 10.1182/blood-2012-01-403766. Epub 2012 Feb 17.


Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilization.

Foeger NC, Norris AJ, Wren LM, Nerbonne JM.

J Biol Chem. 2012 Mar 16;287(12):9640-50. doi: 10.1074/jbc.M111.324574. Epub 2012 Feb 6.


Characterization of a novel, dominant negative KCNJ2 mutation associated with Andersen-Tawil syndrome.

Marrus SB, Cuculich PS, Wang W, Nerbonne JM.

Channels (Austin). 2011 Nov-Dec;5(6):500-9. doi: 10.4161/chan.5.6.18524. Epub 2011 Nov 1.


Enhanced cardiac PI3Kα signalling mitigates arrhythmogenic electrical remodelling in pathological hypertrophy and heart failure.

Yang KC, Jay PY, McMullen JR, Nerbonne JM.

Cardiovasc Res. 2012 Feb 1;93(2):252-62. doi: 10.1093/cvr/cvr283. Epub 2011 Oct 27.


Loss-of-function DNA sequence variant in the CLCNKA chloride channel implicates the cardio-renal axis in interindividual heart failure risk variation.

Cappola TP, Matkovich SJ, Wang W, van Booven D, Li M, Wang X, Qu L, Sweitzer NK, Fang JC, Reilly MP, Hakonarson H, Nerbonne JM, Dorn GW 2nd.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2456-61. doi: 10.1073/pnas.1017494108. Epub 2011 Jan 19.

Supplemental Content

Loading ...
Support Center