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Items: 1 to 50 of 378

1.

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome.

Bondu S, Alary AS, Lefèvre C, Houy A, Jung G, Lefebvre T, Rombaut D, Boussaid I, Bousta A, Guillonneau F, Perrier P, Alsafadi S, Wassef M, Margueron R, Rousseau A, Droin N, Cagnard N, Kaltenbach S, Winter S, Kubasch AS, Bouscary D, Santini V, Toma A, Hunault M, Stamatoullas A, Gyan E, Cluzeau T, Platzbecker U, Adès L, Puy H, Stern MH, Karim Z, Mayeux P, Nemeth E, Park S, Ganz T, Kautz L, Kosmider O, Fontenay M.

Sci Transl Med. 2019 Jul 10;11(500). pii: eaav5467. doi: 10.1126/scitranslmed.aav5467.

PMID:
31292266
2.

Circulating Relaxin-1 Level Is a Surrogate Marker of Myocardial Fibrosis in HFrEF.

Simon J, Nemeth E, Nemes A, Husveth-Toth M, Radovits T, Foldes G, Kiss L, Bagyura Z, Skopal J, Merkely B, Gara E.

Front Physiol. 2019 Jun 4;10:690. doi: 10.3389/fphys.2019.00690. eCollection 2019.

3.

Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence.

Daiello LA, Racine AM, Yun Gou R, Marcantonio ER, Xie Z, Kunze LJ, Vlassakov KV, Inouye SK, Jones RN, Alsop D, Travison T, Arnold S, Cooper Z, Dickerson B, Fong T, Metzger E, Pascual-Leone A, Schmitt EM, Shafi M, Cavallari M, Dai W, Dillon ST, McElhaney J, Guttmann C, Hshieh T, Kuchel G, Libermann T, Ngo L, Press D, Saczynski J, Vasunilashorn S, O'Connor M, Kimchi E, Strauss J, Wong B, Belkin M, Ayres D, Callery M, Pomposelli F, Wright J, Schermerhorn M, Abrantes T, Albuquerque A, Bertrand S, Brown A, Callahan A, D'Aquila M, Dowal S, Fox M, Gallagher J, Anna Gersten R, Hodara A, Helfand B, Inloes J, Kettell J, Kuczmarska A, Nee J, Nemeth E, Ochsner L, Palihnich K, Parisi K, Puelle M, Rastegar S, Vella M, Xu G, Bryan M, Guess J, Enghorn D, Gross A, Gou Y, Habtemariam D, Isaza I, Kosar C, Rockett C, Tommet D, Gruen T, Ross M, Tasker K, Gee J, Kolanowski A, Pisani M, de Rooij S, Rogers S, Studenski S, Stern Y, Whittemore A, Gottlieb G, Orav J, Sperling R; SAGES Study Group*.

Anesthesiology. 2019 Sep;131(3):477-491. doi: 10.1097/ALN.0000000000002729.

PMID:
31166241
4.

To induce or not to induce: the fight over hepcidin regulation.

Sangkhae V, Nemeth E.

Haematologica. 2019 Jun;104(6):1093-1095. doi: 10.3324/haematol.2019.216960. No abstract available.

5.

Y-chromosomal connection between Hungarians and geographically distant populations of the Ural Mountain region and West Siberia.

Post H, Németh E, Klima L, Flores R, Fehér T, Türk A, Székely G, Sahakyan H, Mondal M, Montinaro F, Karmin M, Saag L, Yunusbayev B, Khusnutdinova EK, Metspalu E, Villems R, Tambets K, Rootsi S.

Sci Rep. 2019 May 24;9(1):7786. doi: 10.1038/s41598-019-44272-6.

6.

Treatment of Autosomal Dominant Hypocalcemia Type 1 With the Calcilytic NPSP795 (SHP635).

Roberts MS, Gafni RI, Brillante B, Guthrie LC, Streit J, Gash D, Gelb J, Krusinska E, Brennan SC, Schepelmann M, Riccardi D, Bin Khayat ME, Ward DT, Nemeth EF, Rosskamp R, Collins MT.

J Bone Miner Res. 2019 May 7. doi: 10.1002/jbmr.3747. [Epub ahead of print]

PMID:
31063613
7.

Single versus Split Dose of Iron Optimizes Hemoglobin Mass Gains at 2106 m Altitude.

Hall R, Peeling P, Nemeth E, Bergland D, McCluskey WTP, Stellingwerff T.

Med Sci Sports Exerc. 2019 Apr;51(4):751-759. doi: 10.1249/MSS.0000000000001847.

PMID:
30882751
8.

Iron in Lung Pathology.

Zhang V, Nemeth E, Kim A.

Pharmaceuticals (Basel). 2019 Feb 15;12(1). pii: E30. doi: 10.3390/ph12010030. Review.

9.

Umbilical Cord Serum Ferritin Concentration is Inversely Associated with Umbilical Cord Hemoglobin in Neonates Born to Adolescents Carrying Singletons and Women Carrying Multiples.

Delaney KM, Guillet R, Fleming RE, Ru Y, Pressman EK, Vermeylen F, Nemeth E, O'Brien KO.

J Nutr. 2019 Mar 1;149(3):406-415. doi: 10.1093/jn/nxy286.

PMID:
30770543
10.

The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation.

Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D.

Radiat Res. 2019 Apr;191(4):323-334. doi: 10.1667/RR15231.1. Epub 2019 Feb 7.

PMID:
30730284
11.

Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis.

Chen Q, Yang Y, Hou J, Shu Q, Yin Y, Fu W, Han F, Hou T, Zeng C, Nemeth E, Linzmeier R, Ganz T, Fang X.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3161-3170. doi: 10.1073/pnas.1812947116. Epub 2019 Feb 4.

12.

The genomic imprint of cancer therapies helps timing the formation of metastases.

Németh E, Krzystanek M, Reiniger L, Ribli D, Pipek O, Sztupinszki Z, Glasz T, Csabai I, Moldvay J, Szallasi Z, Szüts D.

Int J Cancer. 2019 Aug 1;145(3):694-704. doi: 10.1002/ijc.32159. Epub 2019 Feb 18.

PMID:
30694556
13.

[Evolution of the Hungarian adult heart transplantation program].

Hartyánszky I, Horkay F, Hüttl T, Fazekas L, Pólos M, Daróczi L, Heltai K, Sax B, Becker D, Németh E, Merkely B, Szabolcs Z.

Orv Hetil. 2018 Nov;159(46):1869-1875. doi: 10.1556/650.2018.31299. Hungarian.

PMID:
30450939
14.

[The Semmelweis University extracorporeal membrane oxygenation program - 5 years' results and perspectives].

Hartyánszky I, Koppányi Á, Szabolcs Z, Horkay F, Fazekas L, Hüttl T, Pólos M, Daróczi L, Kőszegi A, Benke K, Tóth R, Kovács P, Barabás JI, Németh E, Édes IF, Merkely B.

Orv Hetil. 2018 Nov;159(46):1876-1881. doi: 10.1556/650.2018.31298. Hungarian.

PMID:
30450938
15.

Single versus Split Dose of Iron Optimizes Haemoglobin Mass Gains at 2106 m Altitude.

Hall R, Peeling P, Nemeth E, Bergland D, McCluskey WTP, Stellingwerff T.

Med Sci Sports Exerc. 2018 Nov 14. doi: 10.1249/MSS.0000000000001847. [Epub ahead of print]

PMID:
30439788
16.

Iron homeostasis in pregnancy and spontaneous abortion.

Guo Y, Zhang N, Zhang D, Ren Q, Ganz T, Liu S, Nemeth E.

Am J Hematol. 2019 Feb;94(2):184-188. doi: 10.1002/ajh.25341. Epub 2018 Nov 26.

17.

Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload.

Schwartz AJ, Das NK, Ramakrishnan SK, Jain C, Jurkovic MT, Wu J, Nemeth E, Lakhal-Littleton S, Colacino JA, Shah YM.

J Clin Invest. 2019 Jan 2;129(1):336-348. doi: 10.1172/JCI122359. Epub 2018 Dec 10.

18.

Mechanisms responsible for reduced erythropoiesis during androgen deprivation therapy in men with prostate cancer.

Gagliano-Jucá T, Pencina KM, Ganz T, Travison TG, Kantoff PW, Nguyen PL, Taplin ME, Kibel AS, Li Z, Huang G, Edwards RR, Nemeth E, Basaria S.

Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1185-E1193. doi: 10.1152/ajpendo.00272.2018. Epub 2018 Oct 16.

PMID:
30325657
19.

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice.

Coffey R, Sardo U, Kautz L, Gabayan V, Nemeth E, Ganz T.

Physiol Rep. 2018 Sep;6(19):e13890. doi: 10.14814/phy2.13890.

20.

Calcium is an essential cofactor for metal efflux by the ferroportin transporter family.

Deshpande CN, Ruwe TA, Shawki A, Xin V, Vieth KR, Valore EV, Qiao B, Ganz T, Nemeth E, Mackenzie B, Jormakka M.

Nat Commun. 2018 Aug 6;9(1):3075. doi: 10.1038/s41467-018-05446-4.

21.

Retraction Note: Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells.

Ogura J, Babu E, Miyauchi S, Ramachandran S, Nemeth E, Bhutia YD, Ganapathy V.

Sci Rep. 2018 Jul 17;8(1):11021. doi: 10.1038/s41598-018-28645-x.

22.

Effects of erythropoietin on fibroblast growth factor 23 in mice and humans.

Hanudel MR, Eisenga MF, Rappaport M, Chua K, Qiao B, Jung G, Gabayan V, Gales B, Ramos G, de Jong MA, van Zanden JJ, de Borst MH, Bakker SJL, Nemeth E, Salusky IB, Gaillard CAJM, Ganz T.

Nephrol Dial Transplant. 2018 Jul 10. doi: 10.1093/ndt/gfy189. [Epub ahead of print]

PMID:
30007314
23.

Placental iron transport: The mechanism and regulatory circuits.

Sangkhae V, Nemeth E.

Free Radic Biol Med. 2019 Mar;133:254-261. doi: 10.1016/j.freeradbiomed.2018.07.001. Epub 2018 Jul 5. Review.

PMID:
29981833
24.

Acute thrombosis of the ascending aorta causing right ventricular failure: first manifestation of antiphospholipid syndrome.

Pólos M, Kovács A, Németh E, Merkely B.

Eur J Cardiothorac Surg. 2019 Feb 1;55(2):371-373. doi: 10.1093/ejcts/ezy218.

PMID:
29868867
25.

Response to Ivey-Miranda and Farrero-Torres "Is there dominance of free wall radial motion in global right ventricular function in heart transplant recipients or in all heart surgery patients?"

Kovács A, Lakatos B, Németh E, Merkely B.

Clin Transplant. 2018 Jul;32(7):e13286. doi: 10.1111/ctr.13286. Epub 2018 Jun 3. No abstract available.

PMID:
29862572
26.

[Perioperative use of levosimendan in cardiac surgery. Hungarian recommendation].

Szudi L, Székely L, Sápi E, Prodán Z, Szolnoky J, Csomós Á, Nyolczas N, Paulovich E, Németh E, Hartyánszky I, Zima E, Sax B, Bertalan A, Hejjel L, Bogáts G, Babik B, Gombocz K, Szerafin T, Koszta G, Molnár A.

Orv Hetil. 2018 Jun;159(22):870-877. doi: 10.1556/650.2018.31083. Hungarian.

PMID:
29806474
27.

Continuous cytokine haemoadsorption incorporated into a venoarterial ECMO circuit for the management of postcardiotomy cardiogenic and septic shock - a case report.

Nemeth E, Szigeti S, Varga T, Daroczi L, Barati Z, Merkely B, Gal J.

Perfusion. 2018 Oct;33(7):593-596. doi: 10.1177/0267659118777442. Epub 2018 May 19.

PMID:
29779449
28.

Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients.

Stefanova D, Raychev A, Deville J, Humphries R, Campeau S, Ruchala P, Nemeth E, Ganz T, Bulut Y.

Infect Immun. 2018 Jun 21;86(7). pii: e00253-18. doi: 10.1128/IAI.00253-18. Print 2018 Jul.

29.
30.

Discovery and Development of Calcimimetic and Calcilytic Compounds.

Nemeth EF, Van Wagenen BC, Balandrin MF.

Prog Med Chem. 2018;57(1):1-86. doi: 10.1016/bs.pmch.2017.12.001. Epub 2018 Mar 13. Review.

PMID:
29680147
31.

Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations.

Meznarich JA, Draper L, Christensen RD, Yaish HM, Luem ND, Pysher TJ, Jung G, Nemeth E, Ganz T, Ward DM.

Blood Cells Mol Dis. 2018 Jul;71:63-66. doi: 10.1016/j.bcmd.2018.03.002. Epub 2018 Mar 20.

32.

Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype.

Adams P, Altes A, Brissot P, Butzeck B, Cabantchik I, Cançado R, Distante S, Evans P, Evans R, Ganz T, Girelli D, Hultcrantz R, McLaren G, Marris B, Milman N, Nemeth E, Nielsen P, Pineau B, Piperno A, Porto G, Prince D, Ryan J, Sanchez M, Santos P, Swinkels D, Teixeira E, Toska K, Vanclooster A, White D; Contributors and Hemochromatosis International Taskforce.

Hepatol Int. 2018 Mar;12(2):83-86. doi: 10.1007/s12072-018-9855-0. Epub 2018 Mar 27.

33.

Intravenous Iron Does Not Augment the Hemoglobin Mass Response to Simulated Hypoxia.

Garvican-Lewis LA, Vuong VL, Govus AD, Peeling P, Jung G, Nemeth E, Hughes D, Lovell G, Eichner D, Gore CJ.

Med Sci Sports Exerc. 2018 Aug;50(8):1669-1678. doi: 10.1249/MSS.0000000000001608.

PMID:
29538179
34.

Hepcidin agonists as therapeutic tools.

Casu C, Nemeth E, Rivella S.

Blood. 2018 Apr 19;131(16):1790-1794. doi: 10.1182/blood-2017-11-737411. Epub 2018 Mar 9. Review.

35.
36.

Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease.

Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E.

Haematologica. 2018 Apr;103(4):e141-e142. doi: 10.3324/haematol.2017.181743. Epub 2018 Feb 1. No abstract available.

37.

Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells.

Ogura J, Babu E, Miyauchi S, Ramachandran S, Nemeth E, Bhutia YD, Ganapathy V.

Sci Rep. 2018 Feb 6;8(1):2519. doi: 10.1038/s41598-018-20620-w. Retraction in: Sci Rep. 2018 Jul 17;8(1):11021.

38.

Impact of intraoperative cytokine adsorption on outcome of patients undergoing orthotopic heart transplantation-an observational study.

Nemeth E, Kovacs E, Racz K, Soltesz A, Szigeti S, Kiss N, Csikos G, Koritsanszky KB, Berzsenyi V, Trembickij G, Fabry S, Prohaszka Z, Merkely B, Gal J.

Clin Transplant. 2018 Apr;32(4):e13211. doi: 10.1111/ctr.13211. Epub 2018 Feb 27. Erratum in: Clin Transplant. 2019 Jun;33(6):e13556.

PMID:
29377282
39.

The effects of putrescine are partly overlapping with osmotic stress processes in wheat.

Pál M, Majláth I, Németh E, Hamow KÁ, Szalai G, Rudnóy S, Balassa G, Janda T.

Plant Sci. 2018 Mar;268:67-76. doi: 10.1016/j.plantsci.2017.12.011. Epub 2018 Jan 6.

PMID:
29362086
40.

Dominance of free wall radial motion in global right ventricular function of heart transplant recipients.

Lakatos BK, Tokodi M, Assabiny A, Tősér Z, Kosztin A, Doronina A, Rácz K, Koritsánszky KB, Berzsenyi V, Németh E, Sax B, Kovács A, Merkely B.

Clin Transplant. 2018 Mar;32(3):e13192. doi: 10.1111/ctr.13192. Epub 2018 Jan 20.

PMID:
29315873
41.

Analysis of the vasculature by immunohistochemistry in paraffin-embedded brains.

Decker Y, Müller A, Németh E, Schulz-Schaeffer WJ, Fatar M, Menger MD, Liu Y, Fassbender K.

Brain Struct Funct. 2018 Mar;223(2):1001-1015. doi: 10.1007/s00429-017-1595-8. Epub 2017 Dec 19.

PMID:
29260371
42.

Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin.

Aschemeyer S, Qiao B, Stefanova D, Valore EV, Sek AC, Ruwe TA, Vieth KR, Jung G, Casu C, Rivella S, Jormakka M, Mackenzie B, Ganz T, Nemeth E.

Blood. 2018 Feb 22;131(8):899-910. doi: 10.1182/blood-2017-05-786590. Epub 2017 Dec 13.

43.

Chemical Approach to Biological Safety: Molecular-Level Control of an Integrated Zinc Finger Nuclease.

Németh E, Asaka MN, Kato K, Fábián Z, Oostenbrink C, Christensen HEM, Nagata K, Gyurcsik B.

Chembiochem. 2018 Jan 4;19(1):66-75. doi: 10.1002/cbic.201700420. Epub 2017 Dec 12.

PMID:
29077265
44.

Iron homeostasis during pregnancy.

Fisher AL, Nemeth E.

Am J Clin Nutr. 2017 Dec;106(Suppl 6):1567S-1574S. doi: 10.3945/ajcn.117.155812. Epub 2017 Oct 25. Review.

45.

Stress-induced changes of growth, yield and bioactive compounds in lemon balm cultivars.

Szabó K, Radácsi P, Rajhárt P, Ladányi M, Németh É.

Plant Physiol Biochem. 2017 Oct;119:170-177. doi: 10.1016/j.plaphy.2017.07.019. Epub 2017 Jul 22.

PMID:
28881276
46.

Influence of the postoperative inflammatory response on cognitive decline in elderly patients undergoing on-pump cardiac surgery: a controlled, prospective observational study.

Nemeth E, Vig K, Racz K, Koritsanszky KB, Ronkay KI, Hamvas FP, Borbély C, Eory A, Merkely B, Gal J.

BMC Anesthesiol. 2017 Aug 29;17(1):113. doi: 10.1186/s12871-017-0408-1.

47.

Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow.

Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, Sabbagh Y, Xu L, Srour EF, Alvarez MB, Kacena MA, Salusky IB, Ganz T, Nemeth E, White KE.

Haematologica. 2017 Nov;102(11):e427-e430. doi: 10.3324/haematol.2017.167882. Epub 2017 Aug 17. No abstract available.

48.

Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice.

McLachlan S, Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E, Vulpe CD.

Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1;313(5):G511-G523. doi: 10.1152/ajpgi.00307.2016. Epub 2017 Aug 10.

49.

Higher songs of city birds may not be an individual response to noise.

Zollinger SA, Slater PJB, Nemeth E, Brumm H.

Proc Biol Sci. 2017 Aug 16;284(1860). pii: 20170602. doi: 10.1098/rspb.2017.0602.

50.

Immunoassay for human serum erythroferrone.

Ganz T, Jung G, Naeim A, Ginzburg Y, Pakbaz Z, Walter PB, Kautz L, Nemeth E.

Blood. 2017 Sep 7;130(10):1243-1246. doi: 10.1182/blood-2017-04-777987. Epub 2017 Jul 24.

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