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Items: 1 to 50 of 199

1.

Pedro Brugada and Peter Schwartz share the Lefoulon-Delalande Foundation Scientific Prize 2019.

Alto K, Carpentier A, de Gaetano G, Gros F, Haissaguerre M, Lazdunski M, Nemer M, Noble D, Sabatini DD, Samuelsson B, Taylor DA.

Eur Heart J. 2019 Aug 21;40(32):2670. doi: 10.1093/eurheartj/ehz597. No abstract available.

PMID:
31433852
2.

Synthesis of Sialyl LewisX Glycomimetics Bearing a Bicyclic 3- O,4- C-Fused Galactopyranoside Scaffold.

Simard RD, Joyal M, Gillard L, Di Censo G, Maharsy W, Beauregard J, Colarusso P, Patel KD, Prévost M, Nemer M, Guindon Y.

J Org Chem. 2019 Jun 7;84(11):7372-7387. doi: 10.1021/acs.joc.9b01075. Epub 2019 May 23.

PMID:
31088084
3.

Effects of Neddylation and mTOR Inhibition in Acute Myelogenous Leukemia.

Guo N, Azadniv M, Coppage M, Nemer M, Mendler J, Becker M, Liesveld J.

Transl Oncol. 2019 Apr;12(4):602-613. doi: 10.1016/j.tranon.2019.01.001. Epub 2019 Jan 27.

4.

Canada's call.

Nemer M.

Science. 2018 May 25;360(6391):835. doi: 10.1126/science.aau1744. No abstract available.

PMID:
29798858
5.

GATA6 Regulates Aortic Valve Remodeling, and Its Haploinsufficiency Leads to Right-Left Type Bicuspid Aortic Valve.

Gharibeh L, Komati H, Bossé Y, Boodhwani M, Heydarpour M, Fortier M, Hassanzadeh R, Ngu J, Mathieu P, Body S, Nemer M; Bicuspid Aortic Valve Consortium.

Circulation. 2018 Sep 4;138(10):1025-1038. doi: 10.1161/CIRCULATIONAHA.117.029506.

PMID:
29567669
6.

Angiotensin II Overstimulation Leads to an Increased Susceptibility to Dilated Cardiomyopathy and Higher Mortality in Female Mice.

Mathieu S, El Khoury N, Rivard K, Paradis P, Nemer M, Fiset C.

Sci Rep. 2018 Jan 17;8(1):952. doi: 10.1038/s41598-018-19436-5.

7.

Epigenetic and Posttranscriptional Regulation of CD16 Expression during Human NK Cell Development.

Victor AR, Weigel C, Scoville SD, Chan WK, Chatman K, Nemer MM, Mao C, Young KA, Zhang J, Yu J, Freud AG, Oakes CC, Caligiuri MA.

J Immunol. 2018 Jan 15;200(2):565-572. doi: 10.4049/jimmunol.1701128. Epub 2017 Dec 11.

8.

Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies.

Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME.

Redox Biol. 2018 Apr;14:509-521. doi: 10.1016/j.redox.2017.10.019. Epub 2017 Oct 26.

9.

Criteria for drop generation in multiphase microfluidic devices.

Buttacci JD, Loewenberg M, Roberts CC, Nemer MB, Rao RR.

Phys Rev E. 2017 Jun;95(6-1):063103. doi: 10.1103/PhysRevE.95.063103. Epub 2017 Jun 6.

PMID:
28709301
10.

KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.

Darwich R, Li W, Yamak A, Komati H, Andelfinger G, Sun K, Nemer M.

Hum Mol Genet. 2017 Mar 1;26(5):942-954. doi: 10.1093/hmg/ddx009.

PMID:
28164238
11.

Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts.

Straubinger J, Boldt K, Kuret A, Deng L, Krattenmacher D, Bork N, Desch M, Feil R, Feil S, Nemer M, Ueffing M, Ruth P, Just S, Lukowski R.

FASEB J. 2017 Apr;31(4):1620-1638. doi: 10.1096/fj.201601186. Epub 2017 Jan 30.

PMID:
28138039
12.

Transcription factor PEX1 modulates extracellular matrix turnover through regulation of MMP-9 expression.

Jurado Acosta A, Rysä J, Szabo Z, Moilanen AM, Komati H, Nemer M, Ruskoaho H.

Cell Tissue Res. 2017 Feb;367(2):369-385. doi: 10.1007/s00441-016-2527-2. Epub 2016 Nov 8.

PMID:
27826738
13.

C1q-TNF-Related Protein-9 Promotes Cardiac Hypertrophy and Failure.

Appari M, Breitbart A, Brandes F, Szaroszyk M, Froese N, Korf-Klingebiel M, Mohammadi MM, Grund A, Scharf GM, Wang H, Zwadlo C, Fraccarollo D, Schrameck U, Nemer M, Wong GW, Katus HA, Wollert KC, Müller OJ, Bauersachs J, Heineke J.

Circ Res. 2017 Jan 6;120(1):66-77. doi: 10.1161/CIRCRESAHA.116.309398. Epub 2016 Nov 7.

PMID:
27821723
14.

The pathology and pathobiology of bicuspid aortic valve: State of the art and novel research perspectives.

Mathieu P, Bossé Y, Huggins GS, Della Corte A, Pibarot P, Michelena HI, Limongelli G, Boulanger MC, Evangelista A, Bédard E, Citro R, Body SC, Nemer M, Schoen FJ.

J Pathol Clin Res. 2015 Jun 24;1(4):195-206. doi: 10.1002/cjp2.21. eCollection 2015 Oct.

15.

Antibacterial activity of methylated egg white proteins against pathogenic G(+) and G(-) bacteria matching antibiotics.

Abdel-Shafi S, Osman A, Enan G, El-Nemer M, Sitohy M.

Springerplus. 2016 Jul 4;5(1):983. doi: 10.1186/s40064-016-2625-3. eCollection 2016.

16.

GATA5 mutation homozygosity linked to a double outlet right ventricle phenotype in a Lebanese patient.

Kassab K, Hariri H, Gharibeh L, Fahed AC, Zein M, El-Rassy I, Nemer M, El-Rassi I, Bitar F, Nemer G.

Mol Genet Genomic Med. 2015 Dec 20;4(2):160-71. doi: 10.1002/mgg3.190. eCollection 2016 Mar.

17.

Reduction in Na(+) current by angiotensin II is mediated by PKCα in mouse and human-induced pluripotent stem cell-derived cardiomyocytes.

Mathieu S, El Khoury N, Rivard K, Gélinas R, Goyette P, Paradis P, Nemer M, Fiset C.

Heart Rhythm. 2016 Jun;13(6):1346-54. doi: 10.1016/j.hrthm.2016.02.015. Epub 2016 Feb 24.

PMID:
26921763
18.

Nuclear Receptor-Like Structure and Interaction of Congenital Heart Disease-Associated Factors GATA4 and NKX2-5.

Kinnunen S, Välimäki M, Tölli M, Wohlfahrt G, Darwich R, Komati H, Nemer M, Ruskoaho H.

PLoS One. 2015 Dec 7;10(12):e0144145. doi: 10.1371/journal.pone.0144145. eCollection 2015.

19.

Endothelial Gata5 transcription factor regulates blood pressure.

Messaoudi S, He Y, Gutsol A, Wight A, Hébert RL, Vilmundarson RO, Makrigiannis AP, Chalmers J, Hamet P, Tremblay J, McPherson R, Stewart AFR, Touyz RM, Nemer M.

Nat Commun. 2015 Nov 30;6:8835. doi: 10.1038/ncomms9835.

20.

Repairing hearts with AKT.

Komati H, Nemer M.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13131-2. doi: 10.1073/pnas.1517489112. Epub 2015 Oct 19. No abstract available.

21.

Lung function and respiratory symptoms among female hairdressers in Palestine: a 5-year prospective study.

Nemer M, Kristensen P, Nijem K, Bjertness E, Skare Ø, Skogstad M.

BMJ Open. 2015 Oct 15;5(10):e007857. doi: 10.1136/bmjopen-2015-007857.

22.

Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling.

Straubinger J, Schöttle V, Bork N, Subramanian H, Dünnes S, Russwurm M, Gawaz M, Friebe A, Nemer M, Nikolaev VO, Lukowski R.

J Pharmacol Exp Ther. 2015 Sep;354(3):406-16. doi: 10.1124/jpet.115.226092. Epub 2015 Jul 8.

PMID:
26157043
23.

Identification of embryonic lethal genes in humans by autozygosity mapping and exome sequencing in consanguineous families.

Shamseldin HE, Tulbah M, Kurdi W, Nemer M, Alsahan N, Al Mardawi E, Khalifa O, Hashem A, Kurdi A, Babay Z, Bubshait DK, Ibrahim N, Abdulwahab F, Rahbeeni Z, Hashem M, Alkuraya FS.

Genome Biol. 2015 Jun 3;16:116. doi: 10.1186/s13059-015-0681-6.

24.

Guiding Cardiac Conduction With GATA.

Nemer M, Gharibeh L.

Circ Cardiovasc Genet. 2015 Apr;8(2):247-9. doi: 10.1161/CIRCGENETICS.115.001039. No abstract available.

PMID:
25901035
25.

Airway inflammation and ammonia exposure among female Palestinian hairdressers: a cross-sectional study.

Nemer M, Sikkeland LI, Kasem M, Kristensen P, Nijem K, Bjertness E, Skare Ø, Bakke B, Kongerud J, Skogstad M.

Occup Environ Med. 2015 Jun;72(6):428-34. doi: 10.1136/oemed-2014-102437. Epub 2015 Feb 4.

PMID:
25653315
26.

Novel exons in the tbx5 gene locus generate protein isoforms with distinct expression domains and function.

Yamak A, Georges RO, Sheikh-Hassani M, Morin M, Komati H, Nemer M.

J Biol Chem. 2015 Mar 13;290(11):6844-56. doi: 10.1074/jbc.M114.634451. Epub 2015 Jan 25.

27.

EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner.

Ma CX, Song YL, Xiao L, Xue LX, Li WJ, Laforest B, Komati H, Wang WP, Jia ZQ, Zhou CY, Zou Y, Nemer M, Zhang SF, Bai X, Wu H, Zang MX.

Cell Mol Life Sci. 2015 May;72(10):2005-22. doi: 10.1007/s00018-014-1795-9. Epub 2014 Dec 14.

PMID:
25504289
28.

Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate.

Aries A, Whitcomb J, Shao W, Komati H, Saleh M, Nemer M.

Cell Death Dis. 2014 Dec 11;5:e1566. doi: 10.1038/cddis.2014.524.

29.

Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4.

Gallagher JM, Yamak A, Kirilenko P, Black S, Bochtler M, Lefebvre C, Nemer M, Latinkić BV.

Mech Dev. 2014 Nov;134:31-41. doi: 10.1016/j.mod.2014.09.001. Epub 2014 Sep 21.

30.

Glutaredoxin-2 is required to control oxidative phosphorylation in cardiac muscle by mediating deglutathionylation reactions.

Mailloux RJ, Xuan JY, McBride S, Maharsy W, Thorn S, Holterman CE, Kennedy CR, Rippstein P, deKemp R, da Silva J, Nemer M, Lou M, Harper ME.

J Biol Chem. 2014 May 23;289(21):14812-28. doi: 10.1074/jbc.M114.550574. Epub 2014 Apr 12.

31.

Ageing is a risk factor in imatinib mesylate cardiotoxicity.

Maharsy W, Aries A, Mansour O, Komati H, Nemer M.

Eur J Heart Fail. 2014 Apr;16(4):367-76.

32.

Cyclin D2 is a GATA4 cofactor in cardiogenesis.

Yamak A, Latinkic BV, Dali R, Temsah R, Nemer M.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1415-20. doi: 10.1073/pnas.1312993111. Epub 2014 Jan 13.

33.

Respiratory function and chemical exposures among female hairdressers in Palestine.

Nemer M, Kristensen P, Nijem K, Bjertness E, Skogstad M.

Occup Med (Lond). 2013 Jan;63(1):73-6. doi: 10.1093/occmed/kqs190. Epub 2012 Nov 9.

PMID:
23144124
34.

Rare copy number variants contribute to congenital left-sided heart disease.

Hitz MP, Lemieux-Perreault LP, Marshall C, Feroz-Zada Y, Davies R, Yang SW, Lionel AC, D'Amours G, Lemyre E, Cullum R, Bigras JL, Thibeault M, Chetaille P, Montpetit A, Khairy P, Overduin B, Klaassen S, Hoodless P, Awadalla P, Hussin J, Idaghdour Y, Nemer M, Stewart AF, Boerkoel C, Scherer SW, Richter A, Dubé MP, Andelfinger G.

PLoS Genet. 2012 Sep;8(9):e1002903. doi: 10.1371/journal.pgen.1002903. Epub 2012 Sep 6. Erratum in: PLoS Genet. 2013 Mar;9(3). doi: 10.1371/annotation/8bc63544-9ed4-42ca-a830-e8058ab13bab. Awadalla, Philip [added]; Hussin, Julie [added]; Idaghdour, Youssef [added].

35.

Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts.

Yamak A, Temsah R, Maharsy W, Caron S, Paradis P, Aries A, Nemer M.

Am J Physiol Heart Circ Physiol. 2012 Oct 15;303(8):H1057-66. doi: 10.1152/ajpheart.00250.2012. Epub 2012 Aug 24.

36.

Genetic insights into bicuspid aortic valve formation.

Laforest B, Nemer M.

Cardiol Res Pract. 2012;2012:180297. doi: 10.1155/2012/180297. Epub 2012 Jun 4.

37.

Dissociation of cardiogenic and postnatal myocardial activities of GATA4.

Gallagher JM, Komati H, Roy E, Nemer M, Latinkić BV.

Mol Cell Biol. 2012 Jun;32(12):2214-23. doi: 10.1128/MCB.00218-12. Epub 2012 Apr 2.

38.

Comparison of monodisperse droplet generation in flow-focusing devices with hydrophilic and hydrophobic surfaces.

Roberts CC, Rao RR, Loewenberg M, Brooks CF, Galambos P, Grillet AM, Nemer MB.

Lab Chip. 2012 Apr 21;12(8):1540-7. doi: 10.1039/c2lc21197a. Epub 2012 Mar 8.

PMID:
22398953
39.

Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice.

Yasuda N, Akazawa H, Ito K, Shimizu I, Kudo-Sakamoto Y, Yabumoto C, Yano M, Yamamoto R, Ozasa Y, Minamino T, Naito AT, Oka T, Shiojima I, Tamura K, Umemura S, Paradis P, Nemer M, Komuro I.

Hypertension. 2012 Mar;59(3):627-33. doi: 10.1161/HYPERTENSIONAHA.111.175208. Epub 2012 Jan 30. Erratum in: Hypertension. 2012 May;59(5):e51. Paradis, Pierre [added].

PMID:
22291447
40.

T-box factors: insights into the evolutionary emergence of the complex heart.

Hariri F, Nemer M, Nemer G.

Ann Med. 2012 Nov;44(7):680-93. doi: 10.3109/07853890.2011.607468. Epub 2011 Sep 19. Review.

PMID:
21923612
41.

Overexpression of type 1 angiotensin II receptors impairs excitation-contraction coupling in the mouse heart.

Rivard K, Grandy SA, Douillette A, Paradis P, Nemer M, Allen BG, Fiset C.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H2018-27. doi: 10.1152/ajpheart.01092.2010. Epub 2011 Aug 19.

42.

GATA5 interacts with GATA4 and GATA6 in outflow tract development.

Laforest B, Nemer M.

Dev Biol. 2011 Oct 15;358(2):368-78. doi: 10.1016/j.ydbio.2011.07.037. Epub 2011 Aug 4.

43.

Tectal plate glioblastoma multiforme.

Nemer MD, Blight C, Yeung JT, Fram KM, Karim AS.

Surg Neurol Int. 2011;2:101. doi: 10.4103/2152-7806.83025. Epub 2011 Jul 18.

44.

Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec.

Dubé MP, Bigras JL, Thibeault M, Bureau N, Chetaille P, Richter A, Mercier J, Bellavance M, Rohlicek C, Rozen R, Nemer M, Khairy P, Gendron R, Andelfinger G.

Cardiol Young. 2011 Dec;21(6):654-64. doi: 10.1017/S1047951111000813. Epub 2011 Jul 4.

PMID:
21729494
45.

Loss of Gata5 in mice leads to bicuspid aortic valve.

Laforest B, Andelfinger G, Nemer M.

J Clin Invest. 2011 Jul;121(7):2876-87. doi: 10.1172/JCI44555.

46.

A hand for the epicardium.

Laforest B, Nemer M.

Circ Res. 2011 Apr 15;108(8):900-2. doi: 10.1161/CIRCRESAHA.111.243451. No abstract available.

PMID:
21493919
47.

ZFP260 is an inducer of cardiac hypertrophy and a nuclear mediator of endothelin-1 signaling.

Komati H, Maharsy W, Beauregard J, Hayek S, Nemer M.

J Biol Chem. 2011 Jan 14;286(2):1508-16. doi: 10.1074/jbc.M110.162966. Epub 2010 Nov 4.

48.

An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation.

Nadeau M, Georges RO, Laforest B, Yamak A, Lefebvre C, Beauregard J, Paradis P, Bruneau BG, Andelfinger G, Nemer M.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19356-61. doi: 10.1073/pnas.0914888107. Epub 2010 Oct 25.

49.

[Tbx5 and the heart adaptation to life on earth].

Nemer G, Nemer M.

Med Sci (Paris). 2010 Aug-Sep;26(8-9):699-700. doi: 10.1051/medsci/2010268-9699. French. No abstract available.

50.

Cardiac natriuretic peptides: from basic discovery to clinical practice.

Hayek S, Nemer M.

Cardiovasc Ther. 2011 Dec;29(6):362-76. doi: 10.1111/j.1755-5922.2010.00152.x. Epub 2010 Apr 23. Review.

PMID:
20433683

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