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Items: 1 to 50 of 225

1.

Prostate Cancer Epigenetics: From Basic Mechanisms to Clinical Implications.

Yegnasubramanian S, De Marzo AM, Nelson WG.

Cold Spring Harb Perspect Med. 2018 Jun 29. pii: a030445. doi: 10.1101/cshperspect.a030445. [Epub ahead of print]

PMID:
29959132
2.
3.

BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.

Zhu D, Osuka S, Zhang Z, Reichert ZR, Yang L, Kanemura Y, Jiang Y, You S, Zhang H, Devi NS, Bhattacharya D, Takano S, Gillespie GY, Macdonald T, Tan C, Nishikawa R, Nelson WG, Olson JJ, Van Meir EG.

Cancer Cell. 2018 Jun 11;33(6):1004-1016.e5. doi: 10.1016/j.ccell.2018.05.006.

PMID:
29894688
4.

Cost implications of PSA screening differ by age.

Rao K, Liang S, Cardamone M, Joshu CE, Marmen K, Bhavsar N, Nelson WG, Ballentine Carter H, Albert MC, Platz EA, Pollack CE.

BMC Urol. 2018 May 9;18(1):38. doi: 10.1186/s12894-018-0344-5.

5.

The structure of the nucleus in normal and neoplastic prostate cells: untangling the role of type 2 DNA topoisomerases.

Nelson WG, Haffner MC, Yegnasubramanian S.

Am J Clin Exp Urol. 2018 Apr 1;6(2):107-113. eCollection 2018. Review.

6.

Comprehensive Evaluation of Programmed Death-Ligand 1 Expression in Primary and Metastatic Prostate Cancer.

Haffner MC, Guner G, Taheri D, Netto GJ, Palsgrove DN, Zheng Q, Guedes LB, Kim K, Tsai H, Esopi DM, Lotan TL, Sharma R, Meeker AK, Chinnaiyan AM, Nelson WG, Yegnasubramanian S, Luo J, Mehra R, Antonarakis ES, Drake CG, De Marzo AM.

Am J Pathol. 2018 Jun;188(6):1478-1485. doi: 10.1016/j.ajpath.2018.02.014. Epub 2018 Mar 22.

PMID:
29577933
7.

Effects of microtopographic variation and macroalgal cover on morphometrics and survival of the annual form of eelgrass (Zostera marina).

Nelson WG, Sullivan G.

Aquat. Bot.. 2018 Feb 1;145:37-44. doi: 10.1016/j.aquabot.2017.11.008.

PMID:
29290642
8.

Macrophyte Community Response to Nitrogen Loading and Thermal Stressors in Rapidly Flushed Mesocosm Systems.

Kaldy JE, Brown CA, Nelson WG, Frazier M.

J Exp Mar Bio Ecol. 2017 Dec 1;497:107-119.

PMID:
29225370
9.

The inflammatory microenvironment and microbiome in prostate cancer development.

Sfanos KS, Yegnasubramanian S, Nelson WG, De Marzo AM.

Nat Rev Urol. 2018 Jan;15(1):11-24. doi: 10.1038/nrurol.2017.167. Epub 2017 Oct 31. Review.

PMID:
29089606
10.

Racial/Ethnic Differences in the Associations of Overall and Central Body Fatness with Circulating Hormones and Metabolic Factors in US Men.

Lopez DS, Rohrmann S, Peskoe SB, Joshu CE, Tsilidis KK, Selvin E, Dobs AS, Kanarek N, Canfield S, Nelson WG, Platz EA.

Int J Endocrinol Metab. 2017 Apr 22;15(2):e44926. doi: 10.5812/ijem.44926. eCollection 2017 Apr.

11.

A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts.

Platz EA, Kulac I, Barber JR, Drake CG, Joshu CE, Nelson WG, Lucia MS, Klein EA, Lippman SM, Parnes HL, Thompson IM, Goodman PJ, Tangen CM, De Marzo AM.

Cancer Epidemiol Biomarkers Prev. 2017 Oct;26(10):1549-1557. doi: 10.1158/1055-9965.EPI-17-0503. Epub 2017 Jul 28.

12.

AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination.

Haffner MC, Esopi DM, Chaux A, Gürel M, Ghosh S, Vaghasia AM, Tsai H, Kim K, Castagna N, Lam H, Hicks J, Wyhs N, Biswal Shinohara D, Hurley PJ, Simons BW, Schaeffer EM, Lotan TL, Isaacs WB, Netto GJ, De Marzo AM, Nelson WG, An SS, Yegnasubramanian S.

Nat Commun. 2017 Jul 26;8(1):142. doi: 10.1038/s41467-017-00084-8.

13.

Insight into infection-mediated prostate damage: Contrasting patterns of C-reactive protein and prostate-specific antigen levels during infection.

Milbrandt M, Winter AC, Nevin RL, Pakpahan R, Bradwin G, De Marzo AM, Elliott DJ, Gaydos CA, Isaacs WB, Nelson WG, Rifai N, Sokoll LJ, Zenilman JM, Platz EA, Sutcliffe S.

Prostate. 2017 May;77(13):1325-1334. doi: 10.1002/pros.23392. Epub 2017 Jul 12.

14.

Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations.

Mattox AK, Wang Y, Springer S, Cohen JD, Yegnasubramanian S, Nelson WG, Kinzler KW, Vogelstein B, Papadopoulos N.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4733-4738. doi: 10.1073/pnas.1701382114. Epub 2017 Apr 17.

15.

Improving the Physical Examination-Reply.

Nelson WG, Rosen A, Pronovost PJ.

JAMA. 2016 Oct 4;316(13):1410-1411. doi: 10.1001/jama.2016.12236. No abstract available.

PMID:
27701657
16.

Reengineering the Physical Examination for the New Millennium?

Nelson WG, Rosen A, Pronovost PJ.

JAMA. 2016 Jun 14;315(22):2391-2. doi: 10.1001/jama.2016.4470. No abstract available.

PMID:
27299614
17.

Simultaneous quantitative determination of 5-aza-2'-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors.

Anders NM, Liu J, Wanjiku T, Giovinazzo H, Zhou J, Vaghasia A, Nelson WG, Yegnasubramanian S, Rudek MA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jun 1;1022:38-45. doi: 10.1016/j.jchromb.2016.03.029. Epub 2016 Mar 21.

18.

Association between serum 25-hydroxyvitamin D and serum sex steroid hormones among men in NHANES.

Anic GM, Albanes D, Rohrmann S, Kanarek N, Nelson WG, Bradwin G, Rifai N, McGlynn KA, Platz EA, Mondul AM.

Clin Endocrinol (Oxf). 2016 Aug;85(2):258-66. doi: 10.1111/cen.13062. Epub 2016 Apr 6.

19.

Androgen Deprivation Followed by Acute Androgen Stimulation Selectively Sensitizes AR-Positive Prostate Cancer Cells to Ionizing Radiation.

Hedayati M, Haffner MC, Coulter JB, Raval RR, Zhang Y, Zhou H, Mian O, Knight EJ, Razavi N, Dalrymple S, Isaacs JT, Santos A, Hales R, Nelson WG, Yegnasubramanian S, DeWeese TL.

Clin Cancer Res. 2016 Jul 1;22(13):3310-3319. doi: 10.1158/1078-0432.CCR-15-1147. Epub 2016 Feb 1.

20.

Premalignancy in Prostate Cancer: Rethinking What we Know.

De Marzo AM, Haffner MC, Lotan TL, Yegnasubramanian S, Nelson WG.

Cancer Prev Res (Phila). 2016 Aug;9(8):648-56. doi: 10.1158/1940-6207.CAPR-15-0431. Epub 2016 Jan 26. Review.

21.

Global 5-Hydroxymethylcytosine Levels Are Profoundly Reduced in Multiple Genitourinary Malignancies.

Munari E, Chaux A, Vaghasia AM, Taheri D, Karram S, Bezerra SM, Gonzalez Roibon N, Nelson WG, Yegnasubramanian S, Netto GJ, Haffner MC.

PLoS One. 2016 Jan 19;11(1):e0146302. doi: 10.1371/journal.pone.0146302. eCollection 2016.

22.

Commentary on Huggins and Hodges: "Studies on Prostatic Cancer".

Nelson WG.

Cancer Res. 2016 Jan 15;76(2):186-7. doi: 10.1158/0008-5472.CAN-15-3172. No abstract available.

23.

Inflammation in Benign Prostate Tissue and Prostate Cancer in the Finasteride Arm of the Prostate Cancer Prevention Trial.

Murtola TJ, Gurel B, Umbehr M, Lucia MS, Thompson IM Jr, Goodman PJ, Kristal AR, Parnes HL, Lippman SM, Sutcliffe S, Peskoe SB, Barber JR, Drake CG, Nelson WG, De Marzo AM, Platz EA.

Cancer Epidemiol Biomarkers Prev. 2016 Mar;25(3):463-9. doi: 10.1158/1055-9965.EPI-15-0987. Epub 2015 Dec 29.

24.

Infectious mononucleosis, other infections and prostate-specific antigen concentration as a marker of prostate involvement during infection.

Sutcliffe S, Nevin RL, Pakpahan R, Elliott DJ, Langston ME, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Walsh PC, Zenilman JM, Cersovsky SB, Platz EA.

Int J Cancer. 2016 May 1;138(9):2221-30. doi: 10.1002/ijc.29966. Epub 2016 Jan 21.

25.

GSTP1 Loss results in accumulation of oxidative DNA base damage and promotes prostate cancer cell survival following exposure to protracted oxidative stress.

Mian OY, Khattab MH, Hedayati M, Coulter J, Abubaker-Sharif B, Schwaninger JM, Veeraswamy RK, Brooks JD, Hopkins L, Shinohara DB, Cornblatt B, Nelson WG, Yegnasubramanian S, DeWeese TL.

Prostate. 2016 Feb;76(2):199-206. doi: 10.1002/pros.23111. Epub 2015 Oct 8.

26.

Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization.

Haffner MC, Weier C, Xu MM, Vaghasia A, Gürel B, Gümüşkaya B, Esopi DM, Fedor H, Tan HL, Kulac I, Hicks J, Isaacs WB, Lotan TL, Nelson WG, Yegnasubramanian S, De Marzo AM.

J Pathol. 2016 Jan;238(1):31-41. doi: 10.1002/path.4628. Epub 2015 Oct 14.

27.

Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)-Induced Cancer at Multiple Sites.

Sfanos KS, Canene-Adams K, Hempel H, Yu SH, Simons BW, Schaeffer AJ, Schaeffer EM, Nelson WG, De Marzo AM.

Cancer Prev Res (Phila). 2015 Aug;8(8):683-92. doi: 10.1158/1940-6207.CAPR-15-0090. Epub 2015 May 19.

28.

Intraprostatic inflammation is positively associated with serum PSA in men with PSA <4 ng ml(-1), normal DRE and negative for prostate cancer.

Umbehr MH, Gurel B, Murtola TJ, Sutcliffe S, Peskoe SB, Tangen CM, Goodman PJ, Thompson IM, Lippman SM, Lucia MS, Parnes HL, Drake CG, Nelson WG, De Marzo AM, Platz EA.

Prostate Cancer Prostatic Dis. 2015 Sep;18(3):264-9. doi: 10.1038/pcan.2015.19. Epub 2015 May 5.

29.

Circulating total testosterone and PSA concentrations in a nationally representative sample of men without a diagnosis of prostate cancer.

Peskoe SB, Joshu CE, Rohrmann S, McGlynn KA, Nyante SJ, Bradwin G, Dobs AS, Kanarek N, Nelson WG, Platz EA.

Prostate. 2015 Aug 1;75(11):1167-76. doi: 10.1002/pros.22998. Epub 2015 Apr 28.

30.

A method to identify estuarine water quality exceedances associated with ocean conditions.

Brown CA, Nelson WG.

Environ Monit Assess. 2015 Mar;187(3):133. doi: 10.1007/s10661-015-4347-3. Epub 2015 Feb 21.

PMID:
25701470
31.

A panel of DNA methylation markers reveals extensive methylation in histologically benign prostate biopsy cores from cancer patients.

Brikun I, Nusskern D, Gillen D, Lynn A, Murtagh D, Feczko J, Nelson WG, Freije D.

Biomark Res. 2014 Dec 12;2(1):25. doi: 10.1186/s40364-014-0025-9. eCollection 2014.

32.

Prospective study of human herpesvirus type 8 serostatus and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial.

Sutcliffe S, Till C, Jenkins FJ, Gaydos CA, Goodman PJ, Hoque AM, Hsing AW, Thompson IM, Nelson WG, De Marzo AM, Platz EA.

Cancer Causes Control. 2015 Jan;26(1):35-44. doi: 10.1007/s10552-014-0480-5. Epub 2014 Oct 31.

33.

Association of serum inorganic phosphate with sex steroid hormones and vitamin D in a nationally representative sample of men.

Wulaningsih W, Van Hemelrijck M, Michaelsson K, Kanarek N, Nelson WG, Ix JH, Platz EA, Rohrmann S.

Andrology. 2014 Nov;2(6):967-76. doi: 10.1111/andr.285. Epub 2014 Oct 1.

34.

Epigenetic DNA methylation of antioxidative stress regulator NRF2 in human prostate cancer.

Khor TO, Fuentes F, Shu L, Paredes-Gonzalez X, Yang AY, Liu Y, Smiraglia DJ, Yegnasubramanian S, Nelson WG, Kong AN.

Cancer Prev Res (Phila). 2014 Dec;7(12):1186-97. doi: 10.1158/1940-6207.CAPR-14-0127. Epub 2014 Sep 29.

35.

Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial.

Gurel B, Lucia MS, Thompson IM Jr, Goodman PJ, Tangen CM, Kristal AR, Parnes HL, Hoque A, Lippman SM, Sutcliffe S, Peskoe SB, Drake CG, Nelson WG, De Marzo AM, Platz EA.

Cancer Epidemiol Biomarkers Prev. 2014 May;23(5):847-56. doi: 10.1158/1055-9965.EPI-13-1126. Epub 2014 Apr 18.

36.

Racial variation in sex steroid hormone concentration in black and white men: a meta-analysis.

Richard A, Rohrmann S, Zhang L, Eichholzer M, Basaria S, Selvin E, Dobs AS, Kanarek N, Menke A, Nelson WG, Platz EA.

Andrology. 2014 May;2(3):428-35. doi: 10.1111/j.2047-2927.2014.00206.x. Epub 2014 Mar 20.

37.

Time-Resolved Fluorescence Resonance Energy Transfer Assay for Discovery of Small-Molecule Inhibitors of Methyl-CpG Binding Domain Protein 2.

Wyhs N, Walker D, Giovinazzo H, Yegnasubramanian S, Nelson WG.

J Biomol Screen. 2014 Aug;19(7):1060-9. doi: 10.1177/1087057114526433. Epub 2014 Mar 7.

38.

The association between circulating high-sensitivity C-reactive protein concentration and pathologic measures of colonic inflammation.

Joshu CE, Tsilidis KK, Peskoe SB, Giardiello FM, Dluzniewski PJ, Nelson WG, Iacobuzio-Donahue CA, Platz EA.

Cancer Causes Control. 2014 Apr;25(4):409-18. doi: 10.1007/s10552-014-0343-0. Epub 2014 Jan 17.

39.

Association between endogenous sex steroid hormones and insulin-like growth factor proteins in US men.

Papatheodorou SI, Rohrmann S, Lopez DS, Bradwin G, Joshu CE, Kanarek N, Nelson WG, Rifai N, Platz EA, Tsilidis KK.

Cancer Causes Control. 2014 Mar;25(3):353-63. doi: 10.1007/s10552-013-0336-4. Epub 2014 Jan 7.

40.

Dietary chemoprevention of PhIP induced carcinogenesis in male Fischer 344 rats with tomato and broccoli.

Canene-Adams K, Sfanos KS, Liang CT, Yegnasubramanian S, Nelson WG, Brayton C, De Marzo AM.

PLoS One. 2013 Nov 27;8(11):e79842. doi: 10.1371/journal.pone.0079842. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/1ac6412e-619f-4575-8b63-f5e16bd3252b. PLoS One. 2014;9(1). doi:10.1371/annotation/3fd9703c-a6d9-4715-9c93-cf5279ea4fa6.

41.

Tracking the clonal origin of lethal prostate cancer.

Haffner MC, Mosbruger T, Esopi DM, Fedor H, Heaphy CM, Walker DA, Adejola N, Gürel M, Hicks J, Meeker AK, Halushka MK, Simons JW, Isaacs WB, De Marzo AM, Nelson WG, Yegnasubramanian S.

J Clin Invest. 2013 Nov;123(11):4918-22. doi: 10.1172/JCI70354. Epub 2013 Oct 25.

42.

Association between endogenous sex steroid hormones and inflammatory biomarkers in US men.

Tsilidis KK, Rohrmann S, McGlynn KA, Nyante SJ, Lopez DS, Bradwin G, Feinleib M, Joshu CE, Kanarek N, Nelson WG, Selvin E, Platz EA.

Andrology. 2013 Nov;1(6):919-28. doi: 10.1111/j.2047-2927.2013.00129.x. Epub 2013 Sep 30.

43.

The diet as a cause of human prostate cancer.

Nelson WG, Demarzo AM, Yegnasubramanian S.

Cancer Treat Res. 2014;159:51-68. doi: 10.1007/978-3-642-38007-5_4. Review.

44.

Resistance emerges to second-generation antiandrogens in prostate cancer.

Nelson WG, Yegnasubramanian S.

Cancer Discov. 2013 Sep;3(9):971-4. doi: 10.1158/2159-8290.CD-13-0405.

45.

Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease.

Haffner MC, Pellakuru LG, Ghosh S, Lotan TL, Nelson WG, De Marzo AM, Yegnasubramanian S.

Cell Cycle. 2013 Jun 15;12(12):1835-41. doi: 10.4161/cc.25010. Epub 2013 May 15.

46.

Association of serum calcium with serum sex steroid hormones in men in NHANES III.

Van Hemelrijck M, Michaelsson K, Nelson WG, Kanarek N, Dobs A, Platz EA, Rohrmann S.

Aging Male. 2013 Dec;16(4):151-8. doi: 10.3109/13685538.2013.772133. Epub 2013 May 14.

47.

Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations.

Gerber JM, Gucwa JL, Esopi D, Gurel M, Haffner MC, Vala M, Nelson WG, Jones RJ, Yegnasubramanian S.

Oncotarget. 2013 May;4(5):715-28.

48.

Nucleotide resolution analysis of TMPRSS2 and ERG rearrangements in prostate cancer.

Weier C, Haffner MC, Mosbruger T, Esopi DM, Hicks J, Zheng Q, Fedor H, Isaacs WB, De Marzo AM, Nelson WG, Yegnasubramanian S.

J Pathol. 2013 Jun;230(2):174-83. doi: 10.1002/path.4186.

49.

A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes.

Shinohara DB, Vaghasia AM, Yu SH, Mak TN, Brüggemann H, Nelson WG, De Marzo AM, Yegnasubramanian S, Sfanos KS.

Prostate. 2013 Jun;73(9):1007-15. doi: 10.1002/pros.22648. Epub 2013 Feb 6.

50.

Racial/ethnic differences in serum sex steroid hormone concentrations in US adolescent males.

Lopez DS, Peskoe SB, Joshu CE, Dobs A, Feinleib M, Kanarek N, Nelson WG, Selvin E, Rohrmann S, Platz EA.

Cancer Causes Control. 2013 Apr;24(4):817-26. doi: 10.1007/s10552-013-0154-8. Epub 2013 Jan 25.

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