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Radiation-induced Amplification of TGFB1-induced Mesenchymal Stem Cell-mediated Sodium Iodide Symporter (NIS) Gene 131 I Therapy.

Schug C, Kitzberger C, Sievert W, Spellerberg R, Tutter M, Schmohl KA, Eberlein B, Biedermann T, Steiger K, Zach C, Schwaiger M, Multhoff G, Wagner E, Nelson PJ, Spitzweg C.

Clin Cancer Res. 2019 Jun 13. pii: clincanres.4092.2018. doi: 10.1158/1078-0432.CCR-18-4092. [Epub ahead of print]


Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging.

Muñoz DP, Yannone SM, Daemen A, Sun Y, Vakar-Lopez F, Kawahara M, Freund AM, Rodier F, Wu JD, Desprez PY, Raulet DH, Nelson PS, van 't Veer LJ, Campisi J, Coppé JP.

JCI Insight. 2019 Jun 11;5. pii: 124716. doi: 10.1172/jci.insight.124716.


Clinico-Neuropathological Findings in the Oldest Old from the Georgia Centenarian Study.

Tanprasertsuk J, Johnson EJ, Johnson MA, Poon LW, Nelson PT, Davey A, Martin P, Barbey AK, Barger K, Wang XD, Scott TM.

J Alzheimers Dis. 2019 Jun 4. doi: 10.3233/JAD-181110. [Epub ahead of print]


Skill-mix change in general practice: a qualitative comparison of three 'new' non-medical roles in English primary care.

Nelson PA, Bradley F, Martindale AM, McBride A, Hodgson D.

Br J Gen Pract. 2019 Jun 3. pii: bjgp19X704117. doi: 10.3399/bjgp19X704117. [Epub ahead of print]


Take 10: ten qualitative studies on under-researched groups and hard-to-reach issues in dermatology.

Nelson PA, Magin P, Thompson AR.

Br J Dermatol. 2019 Jun;180(6):1271-1273. doi: 10.1111/bjd.17885. No abstract available.


Publisher Correction: The long tail of oncogenic drivers in prostate cancer.

Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, Han GC, Coleman I, Montgomery B, Pritchard C, Morrissey C, Barbieri CE, Beltran H, Sboner A, Zafeiriou Z, Miranda S, Bielski CM, Penson AV, Tolonen C, Huang FW, Robinson D, Wu YM, Lonigro R, Garraway LA, Demichelis F, Kantoff PW, Taplin ME, Abida W, Taylor BS, Scher HI, Nelson PS, de Bono JS, Rubin MA, Sawyers CL, Chinnaiyan AM; PCF/SU2C International Prostate Cancer Dream Team, Schultz N, Van Allen EM.

Nat Genet. 2019 May 31. doi: 10.1038/s41588-019-0451-6. [Epub ahead of print]


Genomic distinctions between metastatic lower and upper tract urothelial carcinoma revealed through rapid autopsy.

Winters BR, De Sarkar N, Arora S, Bolouri H, Jana S, Vakar-Lopez F, Cheng HH, Schweizer MT, Yu EY, Grivas P, Lee JK, Kollath L, Holt SK, McFerrin L, Ha G, Nelson PS, Montgomery RB, Wright JL, Lam HM, Hsieh AC.

JCI Insight. 2019 May 30;5. pii: 128728. doi: 10.1172/jci.insight.128728.


Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene Mutations.

Schweizer MT, Antonarakis ES, Bismar TA, Guedes LB, Cheng HH, Tretiakova MS, Vakar-Lopez F, Klemfuss N, Konnick EQ, Mostaghel EA, Hsieh AC, Nelson PS, Yu EY, Montgomery RB, True LD, Epstein JI, Lotan TL, Pritchard CC.

JCO Precis Oncol. 2019;3. doi: 10.1200/PO.18.00327. Epub 2019 Apr 18.


Design of The PReferences for Open Versus Endovascular Repair of Abdominal Aortic Aneurysm (PROVE-AAA) Trial.

Columbo JA, Kang R, Spangler EL, Newhall K, Brooke BS, Dosluoglu H, Lee ES, Raffetto JD, Henke PK, Tang GS, Mureebe L, Kougias P, Johanning J, Arya S, Scali ST, Stone DH, Suckow BD, Orion K, Halpern V, O'Connell J, Inhat D, Nelson P, Tzeng E, Zhou W, Barry M, Sirovich B, Goodney PP; PROVE-AAA Study Team.

Ann Vasc Surg. 2019 May 7. pii: S0890-5096(19)30289-4. doi: 10.1016/j.avsg.2019.02.034. [Epub ahead of print] Review.


Spinal dural fistula and anterior spinal artery supply from the same segmental artery: Case report of volumetric T2 MRI diagnosis and rational endovascular treatment.

Shapiro M, Kister I, Raz E, Loh J, Young M, Goldman-Yassen A, Chancellor B, Nelson PK.

Interv Neuroradiol. 2019 May 9:1591019918825017. doi: 10.1177/1591019918825017. [Epub ahead of print]


Upregulation of Scavenger receptor B1 is required for steroidogenic and non-steroidogenic cholesterol metabolism in prostate cancer.

Gordon JA, Noble JW, Midha A, Derakhshan F, Wang G, Adomat HH, Tomlinson Guns ES, Lin YY, Ren S, Collins CC, Nelson PS, Morrisey C, Wasan KM, Cox ME.

Cancer Res. 2019 May 7. pii: canres.2529.2018. doi: 10.1158/0008-5472.CAN-18-2529. [Epub ahead of print]


Tetrac as an anti-angiogenic agent in cancer.

Schmohl KA, Nelson PJ, Spitzweg C.

Endocr Relat Cancer. 2019 Jun 1;26(6):R287-R304. doi: 10.1530/ERC-19-0058. Review.


Genomic correlates of clinical outcome in advanced prostate cancer.

Abida W, Cyrta J, Heller G, Prandi D, Armenia J, Coleman I, Cieslik M, Benelli M, Robinson D, Van Allen EM, Sboner A, Fedrizzi T, Mosquera JM, Robinson BD, De Sarkar N, Kunju LP, Tomlins S, Wu YM, Nava Rodrigues D, Loda M, Gopalan A, Reuter VE, Pritchard CC, Mateo J, Bianchini D, Miranda S, Carreira S, Rescigno P, Filipenko J, Vinson J, Montgomery RB, Beltran H, Heath EI, Scher HI, Kantoff PW, Taplin ME, Schultz N, deBono JS, Demichelis F, Nelson PS, Rubin MA, Chinnaiyan AM, Sawyers CL.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11428-11436. doi: 10.1073/pnas.1902651116. Epub 2019 May 6.


Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, Hokkanen SRK, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey AI, Makkinejad N, Montine TJ, Murayama S, Murray ME, Nag S, Rissman RA, Seeley WW, Sperling RA, White Iii CL, Yu L, Schneider JA.

Brain. 2019 Jun 1;142(6):1503-1527. doi: 10.1093/brain/awz099.


What really matters at the end: perspectives from a patient, a family member and an oncologist.

Koven R, Nelson P, Booth CM.

CMAJ. 2018 Apr 16;190(15):E473-E475. doi: 10.1503/cmaj.171285. No abstract available.


The role of surface charge and pH changes in tropical soils on sorption behaviour of per- and polyfluoroalkyl substances (PFASs).

Oliver DP, Li Y, Orr R, Nelson P, Barnes M, McLaughlin MJ, Kookana RS.

Sci Total Environ. 2019 Jul 10;673:197-206. doi: 10.1016/j.scitotenv.2019.04.055. Epub 2019 Apr 5.


Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms.

Wei X, Zhang L, Zhou Z, Kwon OJ, Zhang Y, Nguyen H, Dumpit R, True L, Nelson P, Dong B, Xue W, Birchmeier W, Taketo MM, Xu F, Creighton CJ, Ittmann MM, Xin L.

Cell Stem Cell. 2019 May 2;24(5):753-768.e6. doi: 10.1016/j.stem.2019.03.010. Epub 2019 Apr 11.


Core fucosylated glycan-dependent inhibitory effect of QSOX1-S on invasion and metastasis of hepatocellular carcinoma.

Zhang XF, Wang J, Jia HL, Zhu WW, Lu L, Ye QH, Nelson PJ, Qin Y, Gao DM, Zhou HJ, Qin LX.

Cell Death Discov. 2019 Apr 3;5:84. doi: 10.1038/s41420-019-0164-8. eCollection 2019.


Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer.

Li S, Fong KW, Gritsina G, Zhang A, Zhao JC, Kim J, Sharp A, Yuan W, Aversa C, Yang XJ, Nelson PS, Feng FY, Chinnaiyan AM, de Bono JS, Morrissey C, Rettig MB, Yu J.

Cancer Res. 2019 May 15;79(10):2580-2592. doi: 10.1158/0008-5472.CAN-18-2812. Epub 2019 Apr 5.


Association of prostate cancer SLCO gene expression with Gleason grade and alterations following androgen deprivation therapy.

Alsinnawi M, Zhang A, Bianchi-Frias D, Burns J, Cho E, Zhang X, Sowalsky A, Ye H, Slee AE, True L, Porter C, Taplin ME, Balk S, Nelson PS, Montgomery RB, Mostaghel EA.

Prostate Cancer Prostatic Dis. 2019 Mar 19. doi: 10.1038/s41391-019-0141-6. [Epub ahead of print]


Listener Factors Explain Little Variability in Self-Adjusted Hearing Aid Gain.

Perry TT, Nelson PB, Van Tasell DJ.

Trends Hear. 2019 Jan-Dec;23:2331216519837124. doi: 10.1177/2331216519837124.


A PDE3A Promoter Polymorphism Regulates cAMP-Induced Transcriptional Activity in Failing Human Myocardium.

Sucharov CC, Nakano SJ, Slavov D, Schwisow JA, Rodriguez E, Nunley K, Medway A, Stafford N, Nelson P, McKinsey TA, Movsesian M, Minobe W, Carroll IA, Taylor MRG, Bristow MR.

J Am Coll Cardiol. 2019 Mar 19;73(10):1173-1184. doi: 10.1016/j.jacc.2018.12.053.


Mechanisms of Localization and Speech Perception with Colocated and Spatially Separated Noise and Speech Maskers Under Single-Sided Deafness with a Cochlear Implant.

Dirks C, Nelson PB, Sladen DP, Oxenham AJ.

Ear Hear. 2019 Mar 7. doi: 10.1097/AUD.0000000000000708. [Epub ahead of print]


Clinical determinants for successful circulating tumor DNA analysis in prostate cancer.

Schweizer MT, Gulati R, Beightol M, Konnick EQ, Cheng HH, Klemfuss N, De Sarkar N, Yu EY, Montgomery RB, Nelson PS, Pritchard CC.

Prostate. 2019 May;79(7):701-708. doi: 10.1002/pros.23778. Epub 2019 Mar 13.


Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis.

Abner EL, Nelson PT, Jicha GA, Cooper GE, Fardo DW, Schmitt FA, Kryscio RJ.

J Alzheimers Dis. 2019;68(2):625-633. doi: 10.3233/JAD-181119.


Corrigendum to "Targeting cancer stem cells and their niche: Perspectives for future therapeutic targets and strategies" [Semin. Cancer Biol. (2018) (August) pii: S1044-579X(18)30045-2, 139-155].

Zhao Y, Dong Q, Li J, Zhang K, Qin J, Zhao J, Sun Q, Wang Z, Wartmann T, Jauch KW, Nelson PJ, Qin L, Bruns C.

Semin Cancer Biol. 2019 Mar 5. pii: S1044-579X(18)30179-2. doi: 10.1016/j.semcancer.2018.12.001. [Epub ahead of print] No abstract available.


Diagnosis and relining techniques for delayed type IIIB endoleaks with the second-generation AFX endograft.

Lemmon G, Barleben A, Nelson P, Garrett HE Jr.

J Vasc Surg Cases Innov Tech. 2019 Feb 15;5(1):51-53. doi: 10.1016/j.jvscit.2018.10.006. eCollection 2019 Mar.


Treatment of advanced gastrointestinal cancer with genetically modified autologous mesenchymal stem cells: Results from the phase 1/2 TREAT-ME-1 trial.

von Einem JC, Guenther C, Volk HD, Grütz G, Hirsch D, Salat C, Stoetzer O, Nelson PJ, Michl M, Modest DP, Holch JW, Angele M, Bruns C, Niess H, Heinemann V.

Int J Cancer. 2019 Feb 23. doi: 10.1002/ijc.32230. [Epub ahead of print]


ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer.

Cato L, de Tribolet-Hardy J, Lee I, Rottenberg JT, Coleman I, Melchers D, Houtman R, Xiao T, Li W, Uo T, Sun S, Kuznik NC, Göppert B, Ozgun F, van Royen ME, Houtsmuller AB, Vadhi R, Rao PK, Li L, Balk SP, Den RB, Trock BJ, Karnes RJ, Jenkins RB, Klein EA, Davicioni E, Gruhl FJ, Long HW, Liu XS, Cato ACB, Lack NA, Nelson PS, Plymate SR, Groner AC, Brown M.

Cancer Cell. 2019 Mar 18;35(3):401-413.e6. doi: 10.1016/j.ccell.2019.01.008. Epub 2019 Feb 14.


Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy.

Chornenkyy Y, Fardo DW, Nelson PT.

Lab Invest. 2019 Feb 11. doi: 10.1038/s41374-019-0196-y. [Epub ahead of print] Review.


Infection risk in endovascular neurointerventions: a comparative analysis of 549 cases with and without prophylactic antibiotic use.

Burkhardt JK, Tanweer O, Litao M, Sharma P, Raz E, Shapiro M, Nelson PK, Riina HA.

J Neurosurg. 2019 Feb 8:1-5. doi: 10.3171/2018.10.JNS182540. [Epub ahead of print]


EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis.

Zhao Y, Ding L, Wang D, Ye Z, He Y, Ma L, Zhu R, Pan Y, Wu Q, Pang K, Hou X, Weroha SJ, Han C, Coleman R, Coleman I, Karnes RJ, Zhang J, Nelson PS, Wang L, Huang H.

EMBO J. 2019 Mar 1;38(5). pii: e99599. doi: 10.15252/embj.201899599. Epub 2019 Feb 5.


Hippocampal Sclerosis, Argyrophilic Grain Disease, and Primary Age-Related Tauopathy.

Jicha GA, Nelson PT.

Continuum (Minneap Minn). 2019 Feb;25(1):208-233. doi: 10.1212/CON.0000000000000697.


TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels.

Nelson PT, Gal Z, Wang WX, Niedowicz DM, Artiushin SC, Wycoff S, Wei A, Jicha GA, Fardo DW.

Neurobiol Dis. 2019 May;125:67-76. doi: 10.1016/j.nbd.2019.01.013. Epub 2019 Jan 23.


Radial Artery Access for Treatment of Posterior Circulation Aneurysms Using the Pipeline Embolization Device: Case Series.

Raz E, Shapiro M, Buciuc R, Nelson PK, Nossek E.

Oper Neurosurg (Hagerstown). 2019 Jan 22. doi: 10.1093/ons/opy378. [Epub ahead of print]


Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy.

Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, Ghajar CM.

Nat Cell Biol. 2019 Feb;21(2):238-250. doi: 10.1038/s41556-018-0267-0. Epub 2019 Jan 21.


Performance of PCA3 and TMPRSS2:ERG urinary biomarkers in prediction of biopsy outcome in the Canary Prostate Active Surveillance Study (PASS).

Newcomb LF, Zheng Y, Faino AV, Bianchi-Frias D, Cooperberg MR, Brown MD, Brooks JD, Dash A, Fabrizio MD, Gleave ME, Liss M, Morgan TM, Thompson IM, Wagner AA, Carroll PR, Nelson PS, Lin DW.

Prostate Cancer Prostatic Dis. 2019 Jan 21. doi: 10.1038/s41391-018-0124-z. [Epub ahead of print]


Research mentoring and scientist identity: insights from undergraduates and their mentors.

Robnett RD, Nelson PA, Zurbriggen EL, Crosby FJ, Chemers MM.

Int J STEM Educ. 2018;5(1):41. doi: 10.1186/s40594-018-0139-y. Epub 2018 Nov 30.


Balloon-assisted tracking technique to overcome intracranial stenosis during thrombectomy for stroke.

Burkhardt JK, Shapiro M, Tanweer O, Litao M, Chancellor B, Raz E, Riina HA, Nelson PK.

J Neurointerv Surg. 2019 Mar;11(3):e1. doi: 10.1136/neurintsurg-2018-014275.rep. Epub 2018 Dec 22.


Balloon-assisted tracking technique to overcome intracranial stenosis during thrombectomy for stroke.

Burkhardt JK, Shapiro M, Tanweer O, Litao M, Chancellor B, Raz E, Riina HA, Nelson PK.

BMJ Case Rep. 2018 Dec 10;11(1). pii: e014275. doi: 10.1136/bcr-2018-014275.


Traumatic brain injury is highly associated with self-reported childhood trauma within a juvenile offender cohort.

Schofield PW, Mason R, Nelson PK, Kenny D, Butler T.

Brain Inj. 2019;33(4):412-418. doi: 10.1080/02699052.2018.1552020. Epub 2018 Dec 2.


Glimepiride Administered in Chow Reversibly Impairs Glucose Tolerance in Mice.

Niedowicz DM, Özcan S, Nelson PT.

J Diabetes Res. 2018 Oct 29;2018:1251345. doi: 10.1155/2018/1251345. eCollection 2018.


Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease.

Dong X, Liao Z, Gritsch D, Hadzhiev Y, Bai Y, Locascio JJ, Guennewig B, Liu G, Blauwendraat C, Wang T, Adler CH, Hedreen JC, Faull RLM, Frosch MP, Nelson PT, Rizzu P, Cooper AA, Heutink P, Beach TG, Mattick JS, Müller F, Scherzer CR.

Nat Neurosci. 2019 Jan;22(1):144-147. doi: 10.1038/s41593-018-0277-z.


ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.

Rotinen M, You S, Yang J, Coetzee SG, Reis-Sobreiro M, Huang WC, Huang F, Pan X, Yáñez A, Hazelett DJ, Chu CY, Steadman K, Morrissey CM, Nelson PS, Corey E, Chung LWK, Freedland SJ, Di Vizio D, Garraway IP, Murali R, Knudsen BS, Freeman MR.

Nat Med. 2018 Dec;24(12):1887-1898. doi: 10.1038/s41591-018-0241-1. Epub 2018 Nov 26.


Racial Disparities in Endovascular Aortic Aneurysm Repair.

Tanious A, Karunathilake N, Toro J, Abu-Hanna A, Boitano LT, Fawcett T, Graves B, Nelson P.

Ann Vasc Surg. 2019 Apr;56:46-51. doi: 10.1016/j.avsg.2018.11.002. Epub 2018 Nov 23.


Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.

Katsumata Y, Nelson PT, Estus S; Alzheimer's Disease Neuroimaging Initiative (ADNI), Fardo DW.

Neurobiol Aging. 2019 Feb;74:135-146. doi: 10.1016/j.neurobiolaging.2018.10.017. Epub 2018 Oct 23.


Toward Better Understanding of Flow Diversion in Bifurcation Aneurysms.

Shapiro M, Shapiro A, Raz E, Becske T, Riina H, Nelson PK.

AJNR Am J Neuroradiol. 2018 Dec;39(12):2278-2283. doi: 10.3174/ajnr.A5874. Epub 2018 Nov 15.


Aortic Arch Variants: A Practical Guide to Safe and Timely Catheterization.

Shapiro M, Raz E, Nelson PK.

Interv Neurol. 2018 Oct;7(6):544-555. doi: 10.1159/000491940. Epub 2018 Sep 13.


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