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Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization.

Yang L, So JY, Skrypek N, Yang HH, Merchant AS, Nelson GW, Chen WD, Ishii H, Chen JM, Hu G, Achyut BR, Yoon EC, Han L, Huang C, Cam MC, Zhao K, Lee MP.

Cancer Res. 2020 Apr 7. pii: canres.3339.2019. doi: 10.1158/0008-5472.CAN-19-3339. [Epub ahead of print]


NPHS2 V260E Is a Frequent Cause of Steroid-Resistant Nephrotic Syndrome in Black South African Children.

Asharam K, Bhimma R, David VA, Coovadia HM, Qulu WP, Naicker T, Gillies CE, Vega-Warner V, Johnson RC, Limou S, Kopp JB, Sampson M, Nelson GW, Winkler CA.

Kidney Int Rep. 2018 Jul 29;3(6):1354-1362. doi: 10.1016/j.ekir.2018.07.017. eCollection 2018 Nov.


Fetal-Not Maternal-APOL1 Genotype Associated with Risk for Preeclampsia in Those with African Ancestry.

Reidy KJ, Hjorten RC, Simpson CL, Rosenberg AZ, Rosenblum SD, Kovesdy CP, Tylavsky FA, Myrie J, Ruiz BL, Haque S, Mozhui K, Nelson GW, David VA, Yang X, Suzuki M, Jacob J, Reznik SE, Kaskel FJ, Kopp JB, Winkler CA, Davis RL.

Am J Hum Genet. 2018 Sep 6;103(3):367-376. doi: 10.1016/j.ajhg.2018.08.002. Epub 2018 Aug 30.


A mouse recapitulating APOL1-associated kidney disease.

Winkler CA, Nelson GW.

Nat Med. 2017 Apr 7;23(4):411-412. doi: 10.1038/nm.4318. No abstract available.


A conducting polymer with enhanced electronic stability applied in cardiac models.

Mawad D, Mansfield C, Lauto A, Perbellini F, Nelson GW, Tonkin J, Bello SO, Carrad DJ, Micolich AP, Mahat MM, Furman J, Payne D, Lyon AR, Gooding JJ, Harding SE, Terracciano CM, Stevens MM.

Sci Adv. 2016 Nov 30;2(11):e1601007. doi: 10.1126/sciadv.1601007. eCollection 2016 Nov.


Novel Modifications to Carbon-Based Electrodes to Improve the Electrochemical Detection of Dopamine.

Jiang L, Nelson GW, Abda J, Foord JS.

ACS Appl Mater Interfaces. 2016 Oct 26;8(42):28338-28348. doi: 10.1021/acsami.6b03879. Epub 2016 Jul 15.


Cellulose-Derived Supercapacitors from the Carbonisation of Filter Paper.

Jiang L, Nelson GW, Kim H, Sim IN, Han SO, Foord JS.

ChemistryOpen. 2015 Oct;4(5):586-9. doi: 10.1002/open.201500150. Epub 2015 Jul 29.


Surface Characterization and in situ Protein Adsorption Studies on Carbene-Modified Polymers.

Nelson GW, Parker EM, Singh K, Blanford CF, Moloney MG, Foord JS.

Langmuir. 2015 Oct 13;31(40):11086-96. doi: 10.1021/acs.langmuir.5b01644. Epub 2015 Oct 3.


Interfacial electron-shuttling processes across KolliphorEL monolayer grafted electrodes.

Nekoueian K, Hotchen CE, Amiri M, Sillanpää M, Nelson GW, Foord JS, Holdway P, Buchard A, Parker SC, Marken F.

ACS Appl Mater Interfaces. 2015 Jul 22;7(28):15458-65. doi: 10.1021/acsami.5b03654. Epub 2015 Jul 9.


Sequencing rare and common APOL1 coding variants to determine kidney disease risk.

Limou S, Nelson GW, Lecordier L, An P, O'hUigin CS, David VA, Binns-Roemer EA, Guiblet WM, Oleksyk TK, Pays E, Kopp JB, Winkler CA.

Kidney Int. 2015 Oct;88(4):754-63. doi: 10.1038/ki.2015.151. Epub 2015 May 20.


ALDsuite: Dense marker MALD using principal components of ancestral linkage disequilibrium.

Johnson RC, Nelson GW, Zagury JF, Winkler CA.

BMC Genet. 2015 Mar 7;16:23. doi: 10.1186/s12863-015-0179-y.


APOL1 toxin, innate immunity, and kidney injury.

Limou S, Dummer PD, Nelson GW, Kopp JB, Winkler CA.

Kidney Int. 2015 Jul;88(1):28-34. doi: 10.1038/ki.2015.109. Epub 2015 Apr 8. Review.


Amplified electron transfer at poly-ethylene-glycol (PEG) grafted electrodes.

Hotchen CE, Maybury IJ, Nelson GW, Foord JS, Holdway P, Marken F.

Phys Chem Chem Phys. 2015 May 7;17(17):11260-8. doi: 10.1039/c5cp01244a.


APOL1 Risk Variants Are Strongly Associated with HIV-Associated Nephropathy in Black South Africans.

Kasembeli AN, Duarte R, Ramsay M, Mosiane P, Dickens C, Dix-Peek T, Limou S, Sezgin E, Nelson GW, Fogo AB, Goetsch S, Kopp JB, Winkler CA, Naicker S.

J Am Soc Nephrol. 2015 Nov;26(11):2882-90. doi: 10.1681/ASN.2014050469. Epub 2015 Mar 18.


APOL1 kidney risk alleles: population genetics and disease associations.

Limou S, Nelson GW, Kopp JB, Winkler CA.

Adv Chronic Kidney Dis. 2014 Sep;21(5):426-33. doi: 10.1053/j.ackd.2014.06.005. Review.


Hydrothermal conversion of one-photon-fluorescent poly(4-vinylpyridine) into two-photon-fluorescent carbon nanodots.

Lawrence K, Xia F, Arrowsmith RL, Ge H, Nelson GW, Foord JS, Felipe-Sotelo M, Evans ND, Mitchels JM, Flower SE, Botchway SW, Wolverson D, Aliev GN, James TD, Pascu SI, Marken F.

Langmuir. 2014 Oct 7;30(39):11746-52. doi: 10.1021/la404866s. Epub 2014 Mar 21.


F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

Schwarz J, Astermark J, Menius ED, Carrington M, Donfield SM, Gomperts ED, Nelson GW, Oldenburg J, Pavlova A, Shapiro AD, Winkler CA, Berntorp E; Hemophilia Inhibitor Genetics Study Combined Cohort.

Haemophilia. 2013 Jan;19(1):113-8. doi: 10.1111/hae.12004. Epub 2012 Sep 7.


Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans.

Lipkowitz MS, Freedman BI, Langefeld CD, Comeau ME, Bowden DW, Kao WH, Astor BC, Bottinger EP, Iyengar SK, Klotman PE, Freedman RG, Zhang W, Parekh RS, Choi MJ, Nelson GW, Winkler CA, Kopp JB; SK Investigators.

Kidney Int. 2013 Jan;83(1):114-20. doi: 10.1038/ki.2012.263. Epub 2012 Jul 25.


HIV-associated nephropathy patients with and without apolipoprotein L1 gene variants have similar clinical and pathological characteristics.

Atta MG, Estrella MM, Kuperman M, Foy MC, Fine DM, Racusen LC, Lucas GM, Nelson GW, Warner AC, Winkler CA, Kopp JB.

Kidney Int. 2012 Aug;82(3):338-43. doi: 10.1038/ki.2012.111. Epub 2012 Apr 11.


Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia.

An P, Li R, Wang JM, Yoshimura T, Takahashi M, Samudralal R, O'Brien SJ, Phair J, Goedert JJ, Kirk GD, Troyer JL, Sezgin E, Buchbinder SP, Donfield S, Nelson GW, Winkler CA.

PLoS Genet. 2011 Oct;7(10):e1002328. doi: 10.1371/journal.pgen.1002328. Epub 2011 Oct 27.


APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy.

Kopp JB, Nelson GW, Sampath K, Johnson RC, Genovese G, An P, Friedman D, Briggs W, Dart R, Korbet S, Mokrzycki MH, Kimmel PL, Limou S, Ahuja TS, Berns JS, Fryc J, Simon EE, Smith MC, Trachtman H, Michel DM, Schelling JR, Vlahov D, Pollak M, Winkler CA.

J Am Soc Nephrol. 2011 Nov;22(11):2129-37. doi: 10.1681/ASN.2011040388. Epub 2011 Oct 13.


Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans.

Freedman BI, Langefeld CD, Lu L, Divers J, Comeau ME, Kopp JB, Winkler CA, Nelson GW, Johnson RC, Palmer ND, Hicks PJ, Bostrom MA, Cooke JN, McDonough CW, Bowden DW.

PLoS Genet. 2011 Jun;7(6):e1002150. doi: 10.1371/journal.pgen.1002150. Epub 2011 Jun 16.


Genome-wide association study implicates PARD3B-based AIDS restriction.

Troyer JL, Nelson GW, Lautenberger JA, Chinn L, McIntosh C, Johnson RC, Sezgin E, Kessing B, Malasky M, Hendrickson SL, Li G, Pontius J, Tang M, An P, Winkler CA, Limou S, Le Clerc S, Delaneau O, Zagury JF, Schuitemaker H, van Manen D, Bream JH, Gomperts ED, Buchbinder S, Goedert JJ, Kirk GD, O'Brien SJ.

J Infect Dis. 2011 May 15;203(10):1491-502. doi: 10.1093/infdis/jir046.


Enhanced TiO2 surface electrochemistry with carbonised layer-by-layer cellulose-PDDA composite films.

Vuorema A, Shariki S, Sillanpää M, Thielemans W, Nelson GW, Foord JS, Dale SE, Bending S, Marken F.

Phys Chem Chem Phys. 2011 May 28;13(20):9857-62. doi: 10.1039/c1cp20532c. Epub 2011 Apr 18.


Accounting for multiple comparisons in a genome-wide association study (GWAS).

Johnson RC, Nelson GW, Troyer JL, Lautenberger JA, Kessing BD, Winkler CA, O'Brien SJ.

BMC Genomics. 2010 Dec 22;11:724. doi: 10.1186/1471-2164-11-724.


MYH9 genetic variants associated with glomerular disease: what is the role for genetic testing?

Kopp JB, Winkler CA, Nelson GW.

Semin Nephrol. 2010 Jul;30(4):409-17. doi: 10.1016/j.semnephrol.2010.06.007.


The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans.

Freedman BI, Kopp JB, Langefeld CD, Genovese G, Friedman DJ, Nelson GW, Winkler CA, Bowden DW, Pollak MR.

J Am Soc Nephrol. 2010 Sep;21(9):1422-6. doi: 10.1681/ASN.2010070730. Epub 2010 Aug 5. Review.


Association of trypanolytic ApoL1 variants with kidney disease in African Americans.

Genovese G, Friedman DJ, Ross MD, Lecordier L, Uzureau P, Freedman BI, Bowden DW, Langefeld CD, Oleksyk TK, Uscinski Knob AL, Bernhardy AJ, Hicks PJ, Nelson GW, Vanhollebeke B, Winkler CA, Kopp JB, Pays E, Pollak MR.

Science. 2010 Aug 13;329(5993):841-5. doi: 10.1126/science.1193032. Epub 2010 Jul 15.


Worldwide distribution of the MYH9 kidney disease susceptibility alleles and haplotypes: evidence of historical selection in Africa.

Oleksyk TK, Nelson GW, An P, Kopp JB, Winkler CA.

PLoS One. 2010 Jul 9;5(7):e11474. doi: 10.1371/journal.pone.0011474.


Admixture mapping comes of age.

Winkler CA, Nelson GW, Smith MW.

Annu Rev Genomics Hum Genet. 2010;11:65-89. doi: 10.1146/annurev-genom-082509-141523. Review.


The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.

Freedman BI, Edberg JC, Comeau ME, Murea M, Bowden DW, Divers J, Alarcón GS, Brown EE, McGwin G Jr, Kopp JB, Winkler CA, Nelson GW, Illei G, Petri M, Ramsey-Goldman R, Reveille JD, Vilá LM, Langefeld CD, Kimberly RP; PROFILE Study Group.

Am J Nephrol. 2010;32(1):66-72. doi: 10.1159/000314688. Epub 2010 Jun 7.


Carbon nanoparticle surface functionalisation: converting negatively charged sulfonate to positively charged sulfonamide.

Watkins JD, Lawrence R, Taylor JE, Bull SD, Nelson GW, Foord JS, Wolverson D, Rassaei L, Evans ND, Gascon SA, Marken F.

Phys Chem Chem Phys. 2010 May 14;12(18):4872-8. doi: 10.1039/b927434k. Epub 2010 Mar 17.


Characterization of covalently bonded proteins on poly(methyl methacrylate) by X-ray photoelectron spectroscopy.

Nelson GW, Perry M, He SM, Zechel DL, Horton JH.

Colloids Surf B Biointerfaces. 2010 Jun 15;78(1):61-8. doi: 10.1016/j.colsurfb.2010.02.012. Epub 2010 Feb 18.


African ancestry allelic variation at the MYH9 gene contributes to increased susceptibility to non-diabetic end-stage kidney disease in Hispanic Americans.

Behar DM, Rosset S, Tzur S, Selig S, Yudkovsky G, Bercovici S, Kopp JB, Winkler CA, Nelson GW, Wasser WG, Skorecki K.

Hum Mol Genet. 2010 May 1;19(9):1816-27. doi: 10.1093/hmg/ddq040. Epub 2010 Feb 9.


Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15.

Nelson GW, Freedman BI, Bowden DW, Langefeld CD, An P, Hicks PJ, Bostrom MA, Johnson RC, Kopp JB, Winkler CA.

Hum Mol Genet. 2010 May 1;19(9):1805-15. doi: 10.1093/hmg/ddq039. Epub 2010 Feb 2.


Multistage genomewide association study identifies a locus at 1q41 associated with rate of HIV-1 disease progression to clinical AIDS.

Herbeck JT, Gottlieb GS, Winkler CA, Nelson GW, An P, Maust BS, Wong KG, Troyer JL, Goedert JJ, Kessing BD, Detels R, Wolinsky SM, Martinson J, Buchbinder S, Kirk GD, Jacobson LP, Margolick JB, Kaslow RA, O'Brien SJ, Mullins JI.

J Infect Dis. 2010 Feb 15;201(4):618-26. doi: 10.1086/649842.


Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD.

Freedman BI, Hicks PJ, Bostrom MA, Comeau ME, Divers J, Bleyer AJ, Kopp JB, Winkler CA, Nelson GW, Langefeld CD, Bowden DW.

Nephrol Dial Transplant. 2009 Nov;24(11):3366-71. doi: 10.1093/ndt/gfp316. Epub 2009 Jun 30.


Lack of Duffy antigen receptor for chemokines: no influence on HIV disease progression in an African treatment-naive population.

Julg B, Reddy S, van der Stok M, Kulkarni S, Qi Y, Bass S, Gold B, Nalls MA, Nelson GW, Walker BD, Carrington M, Ndung'u T.

Cell Host Microbe. 2009 May 8;5(5):413-5; author reply 418-9. doi: 10.1016/j.chom.2009.04.009. No abstract available.


Expression of Duffy antigen receptor for chemokines (DARC) has no effect on HIV-1 acquisition or progression to AIDS in African Americans.

Winkler CA, An P, Johnson R, Nelson GW, Kirk G.

Cell Host Microbe. 2009 May 8;5(5):411-3; author reply 418-9. doi: 10.1016/j.chom.2009.04.010. No abstract available.


Evaluation of nonviral risk factors for nasopharyngeal carcinoma in a high-risk population of Southern China.

Guo X, Johnson RC, Deng H, Liao J, Guan L, Nelson GW, Tang M, Zheng Y, de The G, O'Brien SJ, Winkler CA, Zeng Y.

Int J Cancer. 2009 Jun 15;124(12):2942-7. doi: 10.1002/ijc.24293.


Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans.

Freedman BI, Hicks PJ, Bostrom MA, Cunningham ME, Liu Y, Divers J, Kopp JB, Winkler CA, Nelson GW, Langefeld CD, Bowden DW.

Kidney Int. 2009 Apr;75(7):736-45. doi: 10.1038/ki.2008.701. Epub 2009 Jan 28.


Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with albuminuria in hypertensive African Americans: the HyperGEN study.

Freedman BI, Kopp JB, Winkler CA, Nelson GW, Rao DC, Eckfeldt JH, Leppert MF, Hicks PJ, Divers J, Langefeld CD, Hunt SC.

Am J Nephrol. 2009;29(6):626-32. doi: 10.1159/000194791. Epub 2009 Jan 20.


MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis.

Kopp JB, Smith MW, Nelson GW, Johnson RC, Freedman BI, Bowden DW, Oleksyk T, McKenzie LM, Kajiyama H, Ahuja TS, Berns JS, Briggs W, Cho ME, Dart RA, Kimmel PL, Korbet SM, Michel DM, Mokrzycki MH, Schelling JR, Simon E, Trachtman H, Vlahov D, Winkler CA.

Nat Genet. 2008 Oct;40(10):1175-84. doi: 10.1038/ng.226. Epub 2008 Sep 14.


GSTM1 and GSTT1 gene deletions and the risk for nasopharyngeal carcinoma in Han Chinese.

Guo X, O'Brien SJ, Zeng Y, Nelson GW, Winkler CA.

Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1760-3. doi: 10.1158/1055-9965.EPI-08-0149.


Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survival.

Hendrickson SL, Jacobson LP, Nelson GW, Phair JP, Lautenberger J, Johnson RC, Kingsley L, Margolick JB, Detels R, Goedert JJ, O'Brien SJ.

J Acquir Immune Defic Syndr. 2008 Jul 1;48(3):263-71. doi: 10.1097/QAI.0b013e31816fdc5f.


Detecting AIDS restriction genes: from candidate genes to genome-wide association discovery.

Hutcheson HB, Lautenberger JA, Nelson GW, Pontius JU, Kessing BD, Winkler CA, Smith MW, Johnson R, Stephens R, Phair J, Goedert JJ, Donfield S, O'Brien SJ.

Vaccine. 2008 Jun 6;26(24):2951-65. doi: 10.1016/j.vaccine.2007.12.054. Epub 2008 Feb 1.


Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection.

Javanbakht H, An P, Gold B, Petersen DC, O'Huigin C, Nelson GW, O'Brien SJ, Kirk GD, Detels R, Buchbinder S, Donfield S, Shulenin S, Song B, Perron MJ, Stremlau M, Sodroski J, Dean M, Winkler C.

Virology. 2006 Oct 10;354(1):15-27. Epub 2006 Aug 2.


Genetic factors leading to chronic Epstein-Barr virus infection and nasopharyngeal carcinoma in South East China: study design, methods and feasibility.

Guo XC, Scott K, Liu Y, Dean M, David V, Nelson GW, Johnson RC, Dilks HH, Lautenberger J, Kessing B, Martenson J, Guan L, Sun S, Deng H, Zheng Y, de The G, Liao J, Zeng Y, O'Brien SJ, Winkler CA.

Hum Genomics. 2006 Jun;2(6):365-75.


Using mutual information to measure the impact of multiple genetic factors on AIDS.

Nelson GW, O'Brien SJ.

J Acquir Immune Defic Syndr. 2006 Jul;42(3):347-54.


Haemophilia Inhibitor Genetics Study - evaluation of a model for studies of complex diseases using linkage and association methods.

Berntorp E, Astermark J, Donfield SM, Nelson GW, Oldenburg J, Shapiro AD, Dimichele DM, Ewenstein BM, Gomperts ED, Winkler CA; Hemophilia Inhibitor Genetics Study.

Haemophilia. 2005 Jul;11(4):427-9. No abstract available.


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