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Items: 22

1.

PD-L1- and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease.

Galea R, Nel HJ, Talekar M, Liu X, Ooi JD, Huynh M, Hadjigol S, Robson KJ, Ting YT, Cole S, Cochlin K, Hitchcock S, Zeng B, Yekollu S, Boks M, Goh N, Roberts H, Rossjohn J, Reid HH, Boyd BJ, Malaviya R, Shealy DJ, Baker DG, Madakamutil L, Kitching AR, O'Sullivan BJ, Thomas R.

JCI Insight. 2019 Sep 19;4(18). pii: 126025. doi: 10.1172/jci.insight.126025.

2.

Regulation of Tolerogenic Features on Dexamethasone-Modulated MPLA-Activated Dendritic Cells by MYC.

García-González PA, Maggi J, Schinnerling K, Sepúlveda-Gutiérrez A, Soto L, Neira O, Mehdi AM, Nel HJ, Pesce B, Aravena O, Molina MC, Catalán D, Thomas R, Verdugo RA, Aguillón JC.

Front Immunol. 2019 May 28;10:1171. doi: 10.3389/fimmu.2019.01171. eCollection 2019.

3.

Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles.

Chen AC, Pena OM, Nel HJ, Yerkovich ST, Chang AB, Baines KJ, Gibson PG, Petsky HL, Pizzutto SJ, Hodge S, Masters IB, Buntain HL, Upham JW.

Pediatr Pulmonol. 2018 May;53(5):575-582. doi: 10.1002/ppul.23984. Epub 2018 Mar 24.

PMID:
29575797
4.

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development.

Jansen DTSL, Ramnoruth N, Loh KL, Rossjohn J, Reid HH, Nel HJ, Thomas R.

Front Immunol. 2018 Jan 22;9:8. doi: 10.3389/fimmu.2018.00008. eCollection 2018.

5.

Dexamethasone and Monophosphoryl Lipid A Induce a Distinctive Profile on Monocyte-Derived Dendritic Cells through Transcriptional Modulation of Genes Associated With Essential Processes of the Immune Response.

García-González PA, Schinnerling K, Sepúlveda-Gutiérrez A, Maggi J, Mehdi AM, Nel HJ, Pesce B, Larrondo ML, Aravena O, Molina MC, Catalán D, Thomas R, Verdugo RA, Aguillón JC.

Front Immunol. 2017 Oct 23;8:1350. doi: 10.3389/fimmu.2017.01350. eCollection 2017.

6.

CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin.

Overgaard NH, Cruz JL, Bridge JA, Nel HJ, Frazer IH, La Gruta NL, Blumenthal A, Steptoe RJ, Wells JW.

J Leukoc Biol. 2017 Sep;102(3):837-844. doi: 10.1189/jlb.1AB0217-065R. Epub 2017 Jun 21.

PMID:
28637895
7.

Treatment with Dexamethasone and Monophosphoryl Lipid A Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers Tolerogenic Features.

García-González PA, Schinnerling K, Sepúlveda-Gutiérrez A, Maggi J, Hoyos L, Morales RA, Mehdi AM, Nel HJ, Soto L, Pesce B, Molina MC, Cuchacovich M, Larrondo ML, Neira Ó, Catalán DF, Hilkens CM, Thomas R, Verdugo RA, Aguillón JC.

Front Immunol. 2016 Oct 25;7:458. eCollection 2016.

8.

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients.

Benham H, Nel HJ, Law SC, Mehdi AM, Street S, Ramnoruth N, Pahau H, Lee BT, Ng J, Brunck ME, Hyde C, Trouw LA, Dudek NL, Purcell AW, O'Sullivan BJ, Connolly JE, Paul SK, Lê Cao KA, Thomas R.

Sci Transl Med. 2015 Jun 3;7(290):290ra87. doi: 10.1126/scitranslmed.aaa9301.

PMID:
26041704
9.

Mycobacterium bovis BCG infection severely delays Trichuris muris expulsion and co-infection suppresses immune responsiveness to both pathogens.

Nel HJ, du Plessis N, Kleynhans L, Loxton AG, van Helden PD, Walzl G.

BMC Microbiol. 2014 Jan 17;14:9. doi: 10.1186/1471-2180-14-9.

10.

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis.

Scally SW, Petersen J, Law SC, Dudek NL, Nel HJ, Loh KL, Wijeyewickrema LC, Eckle SB, van Heemst J, Pike RN, McCluskey J, Toes RE, La Gruta NL, Purcell AW, Reid HH, Thomas R, Rossjohn J.

J Exp Med. 2013 Nov 18;210(12):2569-82. doi: 10.1084/jem.20131241. Epub 2013 Nov 4.

11.

Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.

Knosp CA, Schiering C, Spence S, Carroll HP, Nel HJ, Osbourn M, Jackson R, Lyubomska O, Malissen B, Ingram R, Fitzgerald DC, Powrie F, Fallon PG, Johnston JA, Kissenpfennig A.

J Immunol. 2013 Apr 1;190(7):3235-45. doi: 10.4049/jimmunol.1201396. Epub 2013 Mar 1.

12.

Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis.

Scalfone LK, Nel HJ, Gagliardo LF, Cameron JL, Al-Shokri S, Leifer CA, Fallon PG, Appleton JA.

Infect Immun. 2013 Apr;81(4):1354-63. doi: 10.1128/IAI.01307-12. Epub 2013 Feb 12.

13.

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles.

Law SC, Street S, Yu CH, Capini C, Ramnoruth S, Nel HJ, van Gorp E, Hyde C, Lau K, Pahau H, Purcell AW, Thomas R.

Arthritis Res Ther. 2012 May 17;14(3):R118. doi: 10.1186/ar3848.

14.

Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses.

Viejo-Borbolla A, Martinez-Martín N, Nel HJ, Rueda P, Martín R, Blanco S, Arenzana-Seisdedos F, Thelen M, Fallon PG, Alcamí A.

PLoS Pathog. 2012 Feb;8(2):e1002497. doi: 10.1371/journal.ppat.1002497. Epub 2012 Feb 2.

15.

A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins.

Ryan A, Lynch M, Smith SM, Amu S, Nel HJ, McCoy CE, Dowling JK, Draper E, O'Reilly V, McCarthy C, O'Brien J, Ní Eidhin D, O'Connell MJ, Keogh B, Morton CO, Rogers TR, Fallon PG, O'Neill LA, Kelleher D, Loscher CE.

PLoS Pathog. 2011 Jun;7(6):e1002076. doi: 10.1371/journal.ppat.1002076. Epub 2011 Jun 30.

16.

SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses.

Knosp CA, Carroll HP, Elliott J, Saunders SP, Nel HJ, Amu S, Pratt JC, Spence S, Doran E, Cooke N, Jackson R, Swift J, Fitzgerald DC, Heaney LG, Fallon PG, Kissenpfennig A, Johnston JA.

J Exp Med. 2011 Jul 4;208(7):1523-31. doi: 10.1084/jem.20101167. Epub 2011 Jun 6.

17.

Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice.

Nel HJ, Hams E, Saunders SP, Mangan NE, Smith P, Atzberger A, Flavell RA, Akira S, McKenzie AN, Fallon PG.

J Immunol. 2011 Apr 15;186(8):4631-9. doi: 10.4049/jimmunol.1002995. Epub 2011 Mar 11.

18.

Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis.

Downer EJ, Clifford E, Gran B, Nel HJ, Fallon PG, Moynagh PN.

J Biol Chem. 2011 Mar 25;286(12):10316-28. doi: 10.1074/jbc.M110.188599. Epub 2011 Jan 18.

19.

Helminth-derived immunomodulatory molecules.

Adisakwattana P, Saunders SP, Nel HJ, Fallon PG.

Adv Exp Med Biol. 2009;666:95-107. Review.

PMID:
20054978
20.

Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation.

Ni Ainle F, Preston RJ, Jenkins PV, Nel HJ, Johnson JA, Smith OP, White B, Fallon PG, O'Donnell JS.

Blood. 2009 Aug 20;114(8):1658-65. doi: 10.1182/blood-2009-05-222109. Epub 2009 Jun 16.

PMID:
19531655
21.

Association between tuberculosis and a polymorphic NFkappaB binding site in the interferon gamma gene.

Rossouw M, Nel HJ, Cooke GS, van Helden PD, Hoal EG.

Lancet. 2003 May 31;361(9372):1871-2.

PMID:
12788577
22.

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