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Items: 34

1.

Association of FTO Gene Variant (rs8050136) with Type 2 Diabetes and Markers of Obesity, Glycaemic Control and Inflammation.

Bego T, Čaušević A, Dujić T, Malenica M, Velija-Asimi Z, Prnjavorac B, Marc J, Nekvindová J, Palička V, Semiz S.

J Med Biochem. 2019 Mar 3;38(2):153-163. doi: 10.2478/jomb-2018-0023. eCollection 2019 Apr.

2.

Irinotecan toxicity during treatment of metastatic colorectal cancer: focus on pharmacogenomics and personalized medicine.

Paulík A, Nekvindová J, Filip PS.

Tumori. 2018 Dec 5:300891618811283. doi: 10.1177/0300891618811283. [Epub ahead of print]

PMID:
30514181
3.

Are haplotypes in a single methotrexate pathway more predictive for response in rheumatoid arthritis than in different pathways?

Soukup T, Barvik I, Nekvindova J, Veleta T, Kubena AA, Duintjer Tebbens J, Pavek P, Dosedel M.

Pharmacogenomics. 2018 Apr;19(5):379-381. doi: 10.2217/pgs-2016-0182. Epub 2018 Mar 26.

PMID:
29577811
4.

The plausible association of MTHFR and ADORA2A polymorphisms with nodules in rheumatoid arthritis patients treated with methotrexate.

Soukup T, Dosedel M, Nekvindova J, Antonin Kubena A, Tacheci I, Duintjer Tebbens J, Vlcek J, Bradna P, Barvik I, Pavek P.

Pharmacogenet Genomics. 2017 Feb;27(2):43-50. doi: 10.1097/FPC.0000000000000256.

PMID:
27846189
5.

Aberrant methylation of tumour suppressor genes WT1, GATA5 and PAX5 in hepatocellular carcinoma.

Mžik M, Chmelařová M, John S, Laco J, Slabý O, Kiss I, Bohovicová L, Palička V, Nekvindová J.

Clin Chem Lab Med. 2016 Dec 1;54(12):1971-1980. doi: 10.1515/cclm-2015-1198.

PMID:
27171388
6.

Methotrexate impact on radiographic progression in biologic-treated rheumatoid arthritis under clinical remission: A case report on monozygotic Caucasian twins.

Soukup T, Nekvindova J, Dosedel M, Brtkova J, Toms J, Bastecka D, Bradna P, Vlcek J, Pavek P.

Int J Immunopathol Pharmacol. 2016 Dec;29(4):790-795. Epub 2016 Oct 21.

7.

Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells.

Lauková J, Kozubík A, Hofmanová J, Nekvindová J, Sova P, Moyer MP, Ehrmann J, Hyršlová Vaculová A.

PLoS One. 2015 Oct 22;10(10):e0141020. doi: 10.1371/journal.pone.0141020. eCollection 2015.

8.

Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma.

Besse L, Sedlarikova L, Kryukov F, Nekvindova J, Radova L, Slaby O, Kuglik P, Almasi M, Penka M, Krejci M, Adam Z, Pour L, Sevcikova S, Hajek R.

PLoS One. 2015 Sep 21;10(9):e0137294. doi: 10.1371/journal.pone.0137294. eCollection 2015.

9.

Cervical microbiota in women with preterm prelabor rupture of membranes.

Kacerovsky M, Vrbacky F, Kutova R, Pliskova L, Andrys C, Musilova I, Menon R, Lamont R, Nekvindova J.

PLoS One. 2015 May 20;10(5):e0126884. doi: 10.1371/journal.pone.0126884. eCollection 2015.

10.

Genetic polymorphisms in metabolic pathways of leflunomide in the treatment of rheumatoid arthritis.

Soukup T, Dosedel M, Nekvindova J, Toms J, Vlcek J, Pavek P.

Clin Exp Rheumatol. 2015 May-Jun;33(3):426-32. Epub 2015 Jan 29. Review.

PMID:
25664505
11.

The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients.

Soukup T, Dosedel M, Pavek P, Nekvindova J, Barvik I, Bubancova I, Bradna P, Kubena AA, Carazo AF, Veleta T, Vlcek J.

Rheumatol Int. 2015 Jul;35(7):1149-61. doi: 10.1007/s00296-015-3219-z. Epub 2015 Jan 25.

PMID:
25618758
12.

Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia.

Kubiczkova Besse L, Sedlarikova L, Kryukov F, Nekvindova J, Radova L, Almasi M, Pelcova J, Minarik J, Pika T, Pikalova Z, Scudla V, Krejci M, Adam Z, Pour L, Hajek R, Sevcikova S.

Am J Hematol. 2015 Mar;90(3):E51-2. doi: 10.1002/ajh.23910. Epub 2015 Jan 16. No abstract available.

13.

Risk Score based on microRNA expression signature is independent prognostic classifier of glioblastoma patients.

Sana J, Radova L, Lakomy R, Kren L, Fadrus P, Smrcka M, Besse A, Nekvindova J, Hermanova M, Jancalek R, Svoboda M, Hajduch M, Slampa P, Vyzula R, Slaby O.

Carcinogenesis. 2014 Dec;35(12):2756-62. doi: 10.1093/carcin/bgu212. Epub 2014 Oct 16.

PMID:
25322872
14.

[MicroRNAs and kidneys].

Stříteská J, Nekvindová J, Cerný V, Palička V.

Cas Lek Cesk. 2014;153(4):187-92. Review. Czech.

PMID:
25199544
15.

Prognostic relevance of angiopoietin-2, fibroblast growth factor-2 and endoglin mRNA expressions in chronic lymphocytic leukemia.

Vrbacky F, Nekvindova J, Rezacova V, Simkovic M, Motyckova M, Belada D, Painuly U, Jiruchova Z, Maly J, Krejsek J, Zak P, Cervinka M, Smolej L.

Neoplasma. 2014;61(5):585-92. doi: 10.4149/neo_2014_071.

PMID:
25030442
16.

Acyclic nucleoside phosphonates: a study on cytochrome P450 gene expression.

Nekvindova J, Contreras JA, Juvan P, Fon Tacer K, Anzenbacher P, Zidek Z, Kopecna Zapletalova M, Rozman D, Anzenbacherova E.

Xenobiotica. 2014 Aug;44(8):708-15. doi: 10.3109/00498254.2014.895880. Epub 2014 Mar 5.

PMID:
24593268
17.

Circulating serum microRNAs as novel diagnostic and prognostic biomarkers for multiple myeloma and monoclonal gammopathy of undetermined significance.

Kubiczkova L, Kryukov F, Slaby O, Dementyeva E, Jarkovsky J, Nekvindova J, Radova L, Greslikova H, Kuglik P, Vetesnikova E, Pour L, Adam Z, Sevcikova S, Hajek R.

Haematologica. 2014 Mar;99(3):511-8. doi: 10.3324/haematol.2013.093500. Epub 2013 Nov 15.

18.

Extension of microRNA expression pattern associated with high-risk neuroblastoma.

Bienertova-Vasku J, Mazanek P, Hezova R, Curdova A, Nekvindova J, Kren L, Sterba J, Slaby O.

Tumour Biol. 2013 Aug;34(4):2315-9. doi: 10.1007/s13277-013-0777-0. Epub 2013 Jun 20.

PMID:
23784455
19.

Methylation analysis of tumour suppressor genes in ovarian cancer using MS-MLPA.

Chmelařová M, Křepinská E, Spaček J, Laco J, Nekvindová J, Palička V.

Folia Biol (Praha). 2012;58(6):246-50.

20.

MicroRNA expression profile associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients.

Svoboda M, Sana J, Fabian P, Kocakova I, Gombosova J, Nekvindova J, Radova L, Vyzula R, Slaby O.

Radiat Oncol. 2012 Nov 20;7:195. doi: 10.1186/1748-717X-7-195.

21.

MiR-210 expression in tumor tissue and in vitro effects of its silencing in renal cell carcinoma.

Redova M, Poprach A, Besse A, Iliev R, Nekvindova J, Lakomy R, Radova L, Svoboda M, Dolezel J, Vyzula R, Slaby O.

Tumour Biol. 2013 Feb;34(1):481-91. doi: 10.1007/s13277-012-0573-2. Epub 2012 Nov 13.

PMID:
23150176
22.

Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients.

Slaby O, Redova M, Poprach A, Nekvindova J, Iliev R, Radova L, Lakomy R, Svoboda M, Vyzula R.

Genes Chromosomes Cancer. 2012 Jul;51(7):707-16. doi: 10.1002/gcc.21957. Epub 2012 Apr 10.

PMID:
22492545
23.

Biologic importance and prognostic significance of selected clinicopathological parameters in patients with oral and oropharyngeal squamous cell carcinoma, with emphasis on smoking, protein p16(INK4a) expression, and HPV status.

Laco J, Nekvindova J, Novakova V, Celakovsky P, Dolezalova H, Tucek L, Vosmikova H, Vosmik M, Neskudlova T, Cermakova E, Hacova M, Sobande FA, Ryska A.

Neoplasma. 2012;59(4):398-408. doi: 10.4149/neo_2012_052.

PMID:
22489695
24.

Identification and functional screening of microRNAs highly deregulated in colorectal cancer.

Faltejskova P, Svoboda M, Srutova K, Mlcochova J, Besse A, Nekvindova J, Radova L, Fabian P, Slaba K, Kiss I, Vyzula R, Slaby O.

J Cell Mol Med. 2012 Nov;16(11):2655-66. doi: 10.1111/j.1582-4934.2012.01579.x.

25.

Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma.

Redova M, Poprach A, Nekvindova J, Iliev R, Radova L, Lakomy R, Svoboda M, Vyzula R, Slaby O.

J Transl Med. 2012 Mar 22;10:55. doi: 10.1186/1479-5876-10-55.

26.

The role of high-risk human papillomavirus infection in oral and oropharyngeal squamous cell carcinoma in non-smoking and non-drinking patients: a clinicopathological and molecular study of 46 cases.

Laco J, Vosmikova H, Novakova V, Celakovsky P, Dolezalova H, Tucek L, Nekvindova J, Vosmik M, Cermakova E, Ryska A.

Virchows Arch. 2011 Feb;458(2):179-87. doi: 10.1007/s00428-010-1037-y. Epub 2011 Jan 11.

PMID:
21221634
27.

Colorectal cancer-specific cytochrome P450 2W1: intracellular localization, glycosylation, and catalytic activity.

Gomez A, Nekvindova J, Travica S, Lee MY, Johansson I, Edler D, Mkrtchian S, Ingelman-Sundberg M.

Mol Pharmacol. 2010 Dec;78(6):1004-11. doi: 10.1124/mol.110.067652. Epub 2010 Aug 30.

PMID:
20805301
28.

IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways.

Wang J, Hu Y, Nekvindova J, Ingelman-Sundberg M, Neve EP.

Biochem Pharmacol. 2010 Nov 15;80(10):1592-600. doi: 10.1016/j.bcp.2010.08.005. Epub 2010 Aug 17.

PMID:
20723539
29.

The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression.

Mwinyi J, Hofmann Y, Pedersen RS, Nekvindová J, Cavaco I, Mkrtchian S, Ingelman-Sundberg M.

Life Sci. 2010 May 8;86(19-20):699-706. doi: 10.1016/j.lfs.2010.02.021. Epub 2010 Mar 4.

PMID:
20206639
30.

New insights into the regulation of CYP2C9 gene expression: the role of the transcription factor GATA-4.

Mwinyi J, Nekvindová J, Cavaco I, Hofmann Y, Pedersen RS, Landman E, Mkrtchian S, Ingelman-Sundberg M.

Drug Metab Dispos. 2010 Mar;38(3):415-21. doi: 10.1124/dmd.109.029405. Epub 2009 Dec 7.

PMID:
19995889
31.

Interactions of food and dietary supplements with drug metabolising cytochrome P450 enzymes.

Nekvindová J, Anzenbacher P.

Ceska Slov Farm. 2007 Jul;56(4):165-73. Review.

PMID:
17969314
32.

In vivo study of the effect of antiviral acyclic nucleotide phosphonate (R)-9-[2-(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and its prodrug tenofovir disoproxil fumarate on rat microsomal cytochrome P450.

Anzenbacherová E, Anzenbacher P, Zídek Z, Buchar E, Kmonícková E, Potmesil P, Nekvindová J, Veinlichová A, Holý A.

Physiol Res. 2008;57(5):761-7. Epub 2007 Oct 11.

33.

Inhibition of human liver microsomal cytochrome P450 activities by adefovir and tenofovir.

Nekvindová J, Masek V, Veinlichová A, Anzenbacherová E, Anzenbacher P, Zídek Z, Holý A.

Xenobiotica. 2006 Dec;36(12):1165-77.

PMID:
17162464
34.

Experimental approaches to studies on drug metabolism and drug interactions in man: interaction of acyclic nucleoside phosphonates with human liver cytochromes P450 and flavin-containing monooxygenase 3.

Matal J, Orság J, Nekvindová J, Anzenbacherová E, Veinlichová A, Anzenbacher P, Zídek Z, Holý A.

Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:27-30.

PMID:
17159773

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