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Items: 13

1.

A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors.

Moores SL, Chiu ML, Bushey BS, Chevalier K, Luistro L, Dorn K, Brezski RJ, Haytko P, Kelly T, Wu SJ, Martin PL, Neijssen J, Parren PW, Schuurman J, Attar RM, Laquerre S, Lorenzi MV, Anderson GM.

Cancer Res. 2016 Jul 1;76(13):3942-53. doi: 10.1158/0008-5472.CAN-15-2833. Epub 2016 May 23.

2.

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.

Labrijn AF, Meesters JI, de Goeij BE, van den Bremer ET, Neijssen J, van Kampen MD, Strumane K, Verploegen S, Kundu A, Gramer MJ, van Berkel PH, van de Winkel JG, Schuurman J, Parren PW.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5145-50. doi: 10.1073/pnas.1220145110. Epub 2013 Mar 11.

3.

Species-specific determinants in the IgG CH3 domain enable Fab-arm exchange by affecting the noncovalent CH3-CH3 interaction strength.

Labrijn AF, Rispens T, Meesters J, Rose RJ, den Bleker TH, Loverix S, van den Bremer ET, Neijssen J, Vink T, Lasters I, Aalberse RC, Heck AJ, van de Winkel JG, Schuurman J, Parren PW.

J Immunol. 2011 Sep 15;187(6):3238-46. doi: 10.4049/jimmunol.1003336. Epub 2011 Aug 12.

4.

Direct antigen presentation and gap junction mediated cross-presentation during apoptosis.

Pang B, Neijssen J, Qiao X, Janssen L, Janssen H, Lippuner C, Neefjes J.

J Immunol. 2009 Jul 15;183(2):1083-90. doi: 10.4049/jimmunol.0900861. Epub 2009 Jun 24.

5.

Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections.

Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL.

J Immunol. 2008 Feb 1;180(3):1704-12.

6.

Gap junction-mediated intercellular communication in the immune system.

Neijssen J, Pang B, Neefjes J.

Prog Biophys Mol Biol. 2007 May-Jun;94(1-2):207-18. Epub 2007 Mar 15. Review.

PMID:
17467043
7.

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy.

Reits EA, Hodge JW, Herberts CA, Groothuis TA, Chakraborty M, Wansley EK, Camphausen K, Luiten RM, de Ru AH, Neijssen J, Griekspoor A, Mesman E, Verreck FA, Spits H, Schlom J, van Veelen P, Neefjes JJ.

J Exp Med. 2006 May 15;203(5):1259-71. Epub 2006 Apr 24.

8.

Cutting edge: HLA-B27 acquires many N-terminal dibasic peptides: coupling cytosolic peptide stability to antigen presentation.

Herberts CA, Neijssen JJ, de Haan J, Janssen L, Drijfhout JW, Reits EA, Neefjes JJ.

J Immunol. 2006 Mar 1;176(5):2697-701.

9.

Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation.

Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL.

J Immunol. 2005 Nov 15;175(10):6605-14.

10.

MHC class I alleles and their exploration of the antigen-processing machinery.

Groothuis TA, Griekspoor AC, Neijssen JJ, Herberts CA, Neefjes JJ.

Immunol Rev. 2005 Oct;207:60-76. Review.

PMID:
16181327
11.

Cross-presentation by intercellular peptide transfer through gap junctions.

Neijssen J, Herberts C, Drijfhout JW, Reits E, Janssen L, Neefjes J.

Nature. 2005 Mar 3;434(7029):83-8.

12.

A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation.

Reits E, Neijssen J, Herberts C, Benckhuijsen W, Janssen L, Drijfhout JW, Neefjes J.

Immunity. 2004 Apr;20(4):495-506.

13.

Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

Reits E, Griekspoor A, Neijssen J, Groothuis T, Jalink K, van Veelen P, Janssen H, Calafat J, Drijfhout JW, Neefjes J.

Immunity. 2003 Jan;18(1):97-108.

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