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Items: 1 to 50 of 109

1.

Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.

Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard BG, Neidhart M, Stroes ESG, Catapano AL, Bekkering S.

Eur Heart J. 2018 Oct 7;39(38):3521-3527. doi: 10.1093/eurheartj/ehx581.

2.

SAVE-AMD: Safety of VEGF Inhibitors in Age-Related Macular Degeneration.

Enseleit F, Michels S, Sudano I, Stahel M, Zweifel S, Schlager O, Becker M, Winnik S, Nägele M, Flammer AJ, Neidhart M, Graf N, Matter CM, Seifert B, Lüscher TF, Ruschitzka F.

Ophthalmologica. 2017;238(4):205-216. doi: 10.1159/000478665. Epub 2017 Sep 2.

3.

Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.

Tykocinski LO, Lauffer AM, Bohnen A, Kaul NC, Krienke S, Tretter T, Adam I, Mohapatra SR, Saikali P, Löhning M, Neidhart M, Gay S, Oezen I, Platten M, Opitz CA, Lorenz HM.

J Immunol. 2017 Apr 15;198(8):3109-3117. doi: 10.4049/jimmunol.1600600. Epub 2017 Mar 6.

4.

Expression and Regulation of PIWIL-Proteins and PIWI-Interacting RNAs in Rheumatoid Arthritis.

Pleštilová L, Neidhart M, Russo G, Frank-Bertoncelj M, Ospelt C, Ciurea A, Kolling C, Gay RE, Michel BA, Vencovský J, Gay S, Jüngel A.

PLoS One. 2016 Nov 28;11(11):e0166920. doi: 10.1371/journal.pone.0166920. eCollection 2016.

5.

MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts.

Gaur N, Karouzakis E, Glück S, Bagdonas E, Jüngel A, Michel BA, Gay RE, Gay S, Frank-Bertoncelj M, Neidhart M.

RMD Open. 2016 Oct 14;2(2):e000299. eCollection 2016.

6.

Epigenome analysis reveals TBX5 as a novel transcription factor involved in the activation of rheumatoid arthritis synovial fibroblasts.

Karouzakis E, Trenkmann M, Gay RE, Michel BA, Gay S, Neidhart M.

J Immunol. 2014 Nov 15;193(10):4945-51. doi: 10.4049/jimmunol.1400066. Epub 2014 Oct 15.

7.

Clinical criteria replenish high-sensitive troponin and inflammatory markers in the stratification of patients with suspected acute coronary syndrome.

Stähli BE, Yonekawa K, Altwegg LA, Wyss C, Hof D, Fischbacher P, Brauchlin A, Schulthess G, Krayenbühl PA, von Eckardstein A, Hersberger M, Neidhart M, Gay S, Novopashenny I, Wolters R, Frank M, Wischnewsky MB, Lüscher TF, Maier W.

PLoS One. 2014 Jun 3;9(6):e98626. doi: 10.1371/journal.pone.0098626. eCollection 2014.

8.

The metastasis-associated protein S100A4 promotes the inflammatory response of mononuclear cells via the TLR4 signalling pathway in rheumatoid arthritis.

Cerezo LA, Remáková M, Tomčik M, Gay S, Neidhart M, Lukanidin E, Pavelka K, Grigorian M, Vencovský J, Šenolt L.

Rheumatology (Oxford). 2014 Aug;53(8):1520-6. doi: 10.1093/rheumatology/keu031. Epub 2014 Mar 18.

9.

Inhibition of spermidine/spermine N1-acetyltransferase activity: a new therapeutic concept in rheumatoid arthritis.

Neidhart M, Karouzakis E, Jüngel A, Gay RE, Gay S.

Arthritis Rheumatol. 2014 Jul;66(7):1723-33. doi: 10.1002/art.38574.

10.

Genetics: a new interpretation of genetic studies in RA.

Neidhart M, Karouzakis E.

Nat Rev Rheumatol. 2014 Apr;10(4):199-200. doi: 10.1038/nrrheum.2014.21. Epub 2014 Feb 25.

PMID:
24567061
11.

Exposure to mimivirus collagen promotes arthritis.

Shah N, Hülsmeier AJ, Hochhold N, Neidhart M, Gay S, Hennet T.

J Virol. 2014 Jan;88(2):838-45. doi: 10.1128/JVI.03141-13. Epub 2013 Oct 30.

12.

Citrullination enhances the pro-inflammatory response to fibrin in rheumatoid arthritis synovial fibroblasts.

Sanchez-Pernaute O, Filkova M, Gabucio A, Klein M, Maciejewska-Rodrigues H, Ospelt C, Brentano F, Michel BA, Gay RE, Herrero-Beaumont G, Gay S, Neidhart M, Juengel A.

Ann Rheum Dis. 2013 Aug;72(8):1400-6. doi: 10.1136/annrheumdis-2012-201906. Epub 2012 Dec 12.

PMID:
23234648
13.

Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis.

Cooksley-Decasper S, Reiser H, Thommen DS, Biedermann B, Neidhart M, Gawinecka J, Cathomas G, Franzeck FC, Wyss C, Klingenberg R, Nanni P, Roschitzki B, Matter C, Wolint P, Emmert MY, Husmann M, Amann-Vesti B, Maier W, Gay S, Lüscher TF, von Eckardstein A, Hof D.

PLoS One. 2012;7(10):e47985. doi: 10.1371/journal.pone.0047985. Epub 2012 Oct 24.

14.

Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice.

Kesel N, Köhler D, Herich L, Laudien M, Holl-Ulrich K, Jüngel A, Neidhart M, Gay S, Gay RE, Csernok E, Lamprecht P, Gross WL, Schumacher U, Ullrich S.

Am J Pathol. 2012 May;180(5):2144-55. doi: 10.1016/j.ajpath.2012.01.021. Epub 2012 Mar 23.

PMID:
22449947
15.

Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study.

Enseleit F, Sudano I, Périat D, Winnik S, Wolfrum M, Flammer AJ, Fröhlich GM, Kaiser P, Hirt A, Haile SR, Krasniqi N, Matter CM, Uhlenhut K, Högger P, Neidhart M, Lüscher TF, Ruschitzka F, Noll G.

Eur Heart J. 2012 Jul;33(13):1589-97. doi: 10.1093/eurheartj/ehr482. Epub 2012 Jan 11.

16.

Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

Karouzakis E, Gay RE, Gay S, Neidhart M.

Arthritis Rheum. 2012 Jun;64(6):1809-17. doi: 10.1002/art.34340. Epub 2011 Dec 14.

17.

Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance.

Niederer F, Trenkmann M, Ospelt C, Karouzakis E, Neidhart M, Stanczyk J, Kolling C, Gay RE, Detmar M, Gay S, Jüngel A, Kyburz D.

Arthritis Rheum. 2012 Jun;64(6):1771-9. doi: 10.1002/art.34334. Epub 2011 Dec 12.

18.

Myeloid related proteins activate Toll-like receptor 4 in human acute coronary syndromes.

Yonekawa K, Neidhart M, Altwegg LA, Wyss CA, Corti R, Vogl T, Grigorian M, Gay S, Lüscher TF, Maier W.

Atherosclerosis. 2011 Oct;218(2):486-92. doi: 10.1016/j.atherosclerosis.2011.06.020. Epub 2011 Jun 17.

PMID:
21782178
19.

DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts.

Karouzakis E, Rengel Y, Jüngel A, Kolling C, Gay RE, Michel BA, Tak PP, Gay S, Neidhart M, Ospelt C.

Genes Immun. 2011 Dec;12(8):643-52. doi: 10.1038/gene.2011.45. Epub 2011 Jul 14.

20.

The metastasis promoting protein S100A4 is increased in idiopathic inflammatory myopathies.

Cerezo LA, Kuncová K, Mann H, Tomcík M, Zámecník J, Lukanidin E, Neidhart M, Gay S, Grigorian M, Vencovsky J, Senolt L.

Rheumatology (Oxford). 2011 Oct;50(10):1766-72. doi: 10.1093/rheumatology/ker218. Epub 2011 Jun 28.

21.

Epigenetic deregulation in rheumatoid arthritis.

Karouzakis E, Gay RE, Gay S, Neidhart M.

Adv Exp Med Biol. 2011;711:137-49. Review.

PMID:
21627047
22.

Acetaminophen increases blood pressure in patients with coronary artery disease.

Sudano I, Flammer AJ, Périat D, Enseleit F, Hermann M, Wolfrum M, Hirt A, Kaiser P, Hurlimann D, Neidhart M, Gay S, Holzmeister J, Nussberger J, Mocharla P, Landmesser U, Haile SR, Corti R, Vanhoutte PM, Lüscher TF, Noll G, Ruschitzka F.

Circulation. 2010 Nov 2;122(18):1789-96. doi: 10.1161/CIRCULATIONAHA.110.956490. Epub 2010 Oct 18.

PMID:
20956208
23.

Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts.

Neidhart M, Karouzakis E, Schumann GG, Gay RE, Gay S.

Arthritis Rheum. 2010 Sep;62(9):2673-9. doi: 10.1002/art.27567.

24.

Cellular actors, Toll-like receptors, and local cytokine profile in acute coronary syndromes.

Wyss CA, Neidhart M, Altwegg L, Spanaus KS, Yonekawa K, Wischnewsky MB, Corti R, Kucher N, Roffi M, Eberli FR, Amann-Vesti B, Gay S, von Eckardstein A, Lüscher TF, Maier W.

Eur Heart J. 2010 Jun;31(12):1457-69. doi: 10.1093/eurheartj/ehq084. Epub 2010 May 6.

25.

Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression.

Maciejewska-Rodrigues H, Karouzakis E, Strietholt S, Hemmatazad H, Neidhart M, Ospelt C, Gay RE, Michel BA, Pap T, Gay S, Jüngel A.

J Autoimmun. 2010 Aug;35(1):15-22. doi: 10.1016/j.jaut.2009.12.010. Epub 2010 Jan 15.

26.

Functional autoantibodies against serpin E2 in rheumatoid arthritis.

Maciejewska-Rodrigues H, Al-Shamisi M, Hemmatazad H, Ospelt C, Bouton MC, Jäger D, Cope AP, Charles P, Plant D, Distler JH, Gay RE, Michel BA, Knuth A, Neidhart M, Gay S, Jüngel A.

Arthritis Rheum. 2010 Jan;62(1):93-104. doi: 10.1002/art.25038.

27.

DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

Karouzakis E, Gay RE, Michel BA, Gay S, Neidhart M.

Arthritis Rheum. 2009 Dec;60(12):3613-22. doi: 10.1002/art.25018.

28.

Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis.

Oslejsková L, Grigorian M, Hulejová H, Vencovsky J, Pavelka K, Klingelhöfer J, Gay S, Neidhart M, Brabcová H, Suchy D, Senolt L.

Rheumatology (Oxford). 2009 Dec;48(12):1590-4. doi: 10.1093/rheumatology/kep316. Epub 2009 Oct 14.

29.

Correlation of intravascular ultrasound findings with histopathological analysis of thrombus aspirates in patients with very late drug-eluting stent thrombosis.

Cook S, Ladich E, Nakazawa G, Eshtehardi P, Neidhart M, Vogel R, Togni M, Wenaweser P, Billinger M, Seiler C, Gay S, Meier B, Pichler WJ, Jüni P, Virmani R, Windecker S.

Circulation. 2009 Aug 4;120(5):391-9. doi: 10.1161/CIRCULATIONAHA.109.854398. Epub 2009 Jul 20.

PMID:
19620501
30.

Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis.

Jüngel A, Ospelt C, Lesch M, Thiel M, Sunyer T, Schorr O, Michel BA, Gay RE, Kolling C, Flory C, Gay S, Neidhart M.

Ann Rheum Dis. 2010 May;69(5):898-902. doi: 10.1136/ard.2008.106021. Epub 2009 Jun 3.

31.

Epigenetic control in rheumatoid arthritis synovial fibroblasts.

Karouzakis E, Gay RE, Gay S, Neidhart M.

Nat Rev Rheumatol. 2009 May;5(5):266-72. doi: 10.1038/nrrheum.2009.55. Review.

32.

Expression of cathepsin K and matrix metalloproteinase 1 indicate persistent osteodestructive activity in long-standing ankylosing spondylitis.

Neidhart M, Baraliakos X, Seemayer C, Zelder C, Gay RE, Michel BA, Boehm H, Gay S, Braun J.

Ann Rheum Dis. 2009 Aug;68(8):1334-9. doi: 10.1136/ard.2008.092494. Epub 2008 Aug 4.

33.

Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis.

Flammer AJ, Sudano I, Hermann F, Gay S, Forster A, Neidhart M, Künzler P, Enseleit F, Périat D, Hermann M, Nussberger J, Luscher TF, Corti R, Noll G, Ruschitzka F.

Circulation. 2008 Apr 29;117(17):2262-9. doi: 10.1161/CIRCULATIONAHA.107.734384. Epub 2008 Apr 21.

PMID:
18427133
34.

Epigenetic clues to rheumatoid arthritis.

Sánchez-Pernaute O, Ospelt C, Neidhart M, Gay S.

J Autoimmun. 2008 Feb-Mar;30(1-2):12-20. Epub 2007 Dec 26. Review.

PMID:
18155418
35.

The metastasis associated protein S100A4: a potential novel link to inflammation and consequent aggressive behaviour of rheumatoid arthritis synovial fibroblasts.

Oslejsková L, Grigorian M, Gay S, Neidhart M, Senolt L.

Ann Rheum Dis. 2008 Nov;67(11):1499-504. Epub 2007 Dec 4. Review.

PMID:
18056757
36.

Subtractive hybridization.

Distler JH, Distler O, Neidhart M, Gay S.

Methods Mol Med. 2007;135:77-90.

PMID:
17951653
37.

In situ hybridization of synovial tissue.

Kuchen S, Seemayer CA, Neidhart M, Gay RE, Gay S.

Methods Mol Med. 2007;135:65-75.

PMID:
17951652
38.

The dual inhibitor of lipoxygenase and cyclooxygenase ML3000 decreases the expression of CXCR3 ligands.

Ospelt C, Kurowska-Stolarska M, Neidhart M, Michel BA, Gay RE, Laufer S, Gay S.

Ann Rheum Dis. 2008 Apr;67(4):524-9. Epub 2007 Jul 31.

39.

Myeloid-related protein 8/14 complex is released by monocytes and granulocytes at the site of coronary occlusion: a novel, early, and sensitive marker of acute coronary syndromes.

Altwegg LA, Neidhart M, Hersberger M, Müller S, Eberli FR, Corti R, Roffi M, Sütsch G, Gay S, von Eckardstein A, Wischnewsky MB, Lüscher TF, Maier W.

Eur Heart J. 2007 Apr;28(8):941-8. Epub 2007 Mar 26.

PMID:
17387139
40.

Effect of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension.

Flammer AJ, Hermann F, Wiesli P, Schwegler B, Chenevard R, Hürlimann D, Sudano I, Gay S, Neidhart M, Riesen W, Ruschitzka F, Lüscher TF, Noll G, Lehmann R.

J Hypertens. 2007 Apr;25(4):785-91.

PMID:
17351370
41.

Up-regulation of metastasis-promoting S100A4 (Mts-1) in rheumatoid arthritis: putative involvement in the pathogenesis of rheumatoid arthritis.

Klingelhöfer J, Senolt L, Baslund B, Nielsen GH, Skibshøj I, Pavelka K, Neidhart M, Gay S, Ambartsumian N, Hansen BS, Petersen J, Lukanidin E, Grigorian M.

Arthritis Rheum. 2007 Mar;56(3):779-89.

42.

S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases.

Senolt L, Grigorian M, Lukanidin E, Simmen B, Michel BA, Pavelka K, Gay RE, Gay S, Neidhart M.

Ann Rheum Dis. 2006 Dec;65(12):1645-8.

43.

Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis.

Müller-Ladner U, Pap T, Gay RE, Neidhart M, Gay S.

Nat Clin Pract Rheumatol. 2005 Dec;1(2):102-10. Review.

PMID:
16932639
44.

Molecular and cellular basis of rheumatoid joint destruction.

Karouzakis E, Neidhart M, Gay RE, Gay S.

Immunol Lett. 2006 Jul 15;106(1):8-13. Epub 2006 May 24. Review.

PMID:
16824621
45.

S100A4 (Mts1): is there any relation to the pathogenesis of rheumatoid arthritis?

Senolt L, Grigorian M, Lukanidin E, Michel BA, Gay RE, Gay S, Pavelka K, Neidhart M.

Autoimmun Rev. 2006 Feb;5(2):129-31. Epub 2005 Oct 3. Review.

PMID:
16431343
46.

Trichostatin A sensitises rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis.

Jüngel A, Baresova V, Ospelt C, Simmen BR, Michel BA, Gay RE, Gay S, Seemayer CA, Neidhart M.

Ann Rheum Dis. 2006 Jul;65(7):910-2. Epub 2005 Nov 10.

47.

Deficient expression of interleukin-10 receptor alpha chain in rheumatoid arthritis synovium: limitation of animal models of inflammation.

Neidhart M, Jüngel A, Ospelt C, Michel BA, Gay RE, Gay S.

Arthritis Rheum. 2005 Oct;52(10):3315-8. No abstract available.

48.

Gene analysis for exploring the effects of drugs in rheumatoid arthritis.

Ospelt C, Neidhart M, Gay RE, Gay S.

Arthritis Rheum. 2005 Aug;52(8):2248-56. Review. No abstract available.

49.

Inflammatory markers at the site of ruptured plaque in acute myocardial infarction: locally increased interleukin-6 and serum amyloid A but decreased C-reactive protein.

Maier W, Altwegg LA, Corti R, Gay S, Hersberger M, Maly FE, Sütsch G, Roffi M, Neidhart M, Eberli FR, Tanner FC, Gobbi S, von Eckardstein A, Lüscher TF.

Circulation. 2005 Mar 22;111(11):1355-61. Epub 2005 Mar 7.

PMID:
15753219
50.

Simvastatin improves endothelial function in patients with rheumatoid arthritis.

Hermann F, Forster A, Chenevard R, Enseleit F, Hürlimann D, Corti R, Spieker LE, Frey D, Hermann M, Riesen W, Neidhart M, Michel BA, Hellermann JP, Gay RE, Lüscher TF, Gay S, Noll G, Ruschitzka F.

J Am Coll Cardiol. 2005 Feb 1;45(3):461-4. No abstract available.

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