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Items: 1 to 50 of 141

1.

Functional Analysis of Brain-Engrafted Monocytes After Microglia Ablation in Mouse Models.

Varvel NH, Ransohoff RM, Neher JJ.

Methods Mol Biol. 2019;2034:293-301. doi: 10.1007/978-1-4939-9658-2_22.

PMID:
31392694
2.

Long-Term In Vivo Imaging of Individual Microglial Cells.

Skodras AA, Hefendehl JK, Neher JJ.

Methods Mol Biol. 2019;2034:177-189. doi: 10.1007/978-1-4939-9658-2_13.

PMID:
31392685
3.

Priming Microglia for Innate Immune Memory in the Brain.

Neher JJ, Cunningham C.

Trends Immunol. 2019 Apr;40(4):358-374. doi: 10.1016/j.it.2019.02.001. Epub 2019 Mar 1. Review.

PMID:
30833177
4.

Inflammatory mechanisms in neurodegeneration.

Nichols MR, St-Pierre MK, Wendeln AC, Makoni NJ, Gouwens LK, Garrad EC, Sohrabi M, Neher JJ, Tremblay ME, Combs CK.

J Neurochem. 2019 Jun;149(5):562-581. doi: 10.1111/jnc.14674. Epub 2019 Mar 27. Review.

PMID:
30702751
5.

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.

Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, Tahirovic S, Herms J, Willem M, Pettkus N, Butovsky O, Bartenstein P, Edbauer D, Rominger A, Ertürk A, Grathwohl SA, Neher JJ, Holtzman DM, Meyer-Luehmann M, Haass C.

Nat Neurosci. 2019 Feb;22(2):191-204. doi: 10.1038/s41593-018-0296-9. Epub 2019 Jan 7.

6.

What medical therapies work for gastroparesis?

Wells O, Warcola A, Neher J, Safranek S.

J Fam Pract. 2018 Nov;67(11):720-722. No abstract available.

PMID:
30481252
7.

Clinical Inquiries. How effectively do ACE inhibitors and ARBs prevent migraines?

Morris B, Neher J, Safranek S.

J Fam Pract. 2018 Oct;67(10):652-654. Review. No abstract available.

PMID:
30423002
8.

Morphological changes, nitric oxide production, and phagocytosis are triggered in vitro in microglia by bloodstream forms of Trypanosoma brucei.

Figarella K, Uzcategui NL, Mogk S, Wild K, Fallier-Becker P, Neher JJ, Duszenko M.

Sci Rep. 2018 Oct 9;8(1):15002. doi: 10.1038/s41598-018-33395-x.

9.

Clinical Inquiries. Do statins alter the risk or progression of dementia?

Lang T, Clifton J, Neher J, Safranek S.

J Fam Pract. 2018 Sep;67(9):578-579. No abstract available.

PMID:
30216400
10.

Stage 1 Registered Report: Effect of deficient phagocytosis on neuronal survival and neurological outcome after temporary middle cerebral artery occlusion (tMCAo).

Emmrich JV, Neher JJ, Boehm-Sturm P, Endres M, Dirnagl U, Harms C.

Version 3. F1000Res. 2017 Oct 12 [revised 2018 Jan 1];6:1827. doi: 10.12688/f1000research.12537.3. eCollection 2017.

11.

Clinical Inquiries: How effective and safe is fecal microbial transplant in preventing C difficile recurrence?

Meyers S, Shih J, Neher JO, Safranek S.

J Fam Pract. 2018 Jun;67(6):386-388.

PMID:
29879241
12.

Innate immune memory in the brain shapes neurological disease hallmarks.

Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, Wagner J, Häsler LM, Wild K, Skodras A, Blank T, Staszewski O, Datta M, Centeno TP, Capece V, Islam MR, Kerimoglu C, Staufenbiel M, Schultze JL, Beyer M, Prinz M, Jucker M, Fischer A, Neher JJ.

Nature. 2018 Apr;556(7701):332-338. doi: 10.1038/s41586-018-0023-4. Epub 2018 Apr 11.

13.

Clinical Inquiries: Which interventions are effective in managing parental vaccine refusal?

Brelsford D, Knutzen E, Neher JO, Safranek S.

J Fam Pract. 2017 Dec;66(12):E12-E14. Review.

PMID:
29202149
14.

Patient Willingness to Have Tests to Guide Antibiotic Use for Respiratory Tract Infections: From the WWAMI Region Practice and Research Network (WPRN).

Schwartz M, Hardy V, Keppel GA, Alto W, Hornecker J, Robitaille B, Neher J, Holmes J, Dirac MA, Cole AM, Thompson M.

J Am Board Fam Med. 2017 Sep-Oct;30(5):645-656. doi: 10.3122/jabfm.2017.05.170087.

15.

Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging.

Füger P, Hefendehl JK, Veeraraghavalu K, Wendeln AC, Schlosser C, Obermüller U, Wegenast-Braun BM, Neher JJ, Martus P, Kohsaka S, Thunemann M, Feil R, Sisodia SS, Skodras A, Jucker M.

Nat Neurosci. 2017 Oct;20(10):1371-1376. doi: 10.1038/nn.4631. Epub 2017 Aug 28.

PMID:
28846081
16.

Treatment for Calcaneal Apophysitis.

Uvelli K, Neher JO, Safranek S.

Am Fam Physician. 2017 Jul 15;96(2):126-127. Review. No abstract available.

17.

Erratum: Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota.

Harach T, Marungruang N, Duthilleul N, Cheatham V, Mc Coy KD, Frisoni G, Neher JJ, Fåk F, Jucker M, Lasser T, Bolmont T.

Sci Rep. 2017 Jul 10;7:46856. doi: 10.1038/srep46856.

18.

Clinical Inquiry: Do pedometers increase activity and improve health outcomes?

Schock D, Neher JO, Safranek S.

J Fam Pract. 2017 Jan;66(1):48-53.

PMID:
28188319
19.

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota.

Harach T, Marungruang N, Duthilleul N, Cheatham V, Mc Coy KD, Frisoni G, Neher JJ, Fåk F, Jucker M, Lasser T, Bolmont T.

Sci Rep. 2017 Feb 8;7:41802. doi: 10.1038/srep41802. Erratum in: Sci Rep. 2017 Jul 10;7:46856.

20.

Clinical Inquiries: Does breastfeeding affect the risk of childhood obesity?

Gunnell L, Neher J, Safranek S.

J Fam Pract. 2016 Dec;65(12):931-932. Review.

PMID:
28149981
21.

Qualitative study of primary care clinicians' views on point-of-care testing for C-reactive protein for acute respiratory tract infections in family medicine.

Hardy V, Thompson M, Keppel GA, Alto W, Dirac MA, Neher J, Sanford C, Hornecker J, Cole A.

BMJ Open. 2017 Jan 25;7(1):e012503. doi: 10.1136/bmjopen-2016-012503.

22.

Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus.

Varvel NH, Neher JJ, Bosch A, Wang W, Ransohoff RM, Miller RJ, Dingledine R.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5665-74. doi: 10.1073/pnas.1604263113. Epub 2016 Sep 6.

23.

Conversion of Synthetic Aβ to In Vivo Active Seeds and Amyloid Plaque Formation in a Hippocampal Slice Culture Model.

Novotny R, Langer F, Mahler J, Skodras A, Vlachos A, Wegenast-Braun BM, Kaeser SA, Neher JJ, Eisele YS, Pietrowski MJ, Nilsson KP, Deller T, Staufenbiel M, Heimrich B, Jucker M.

J Neurosci. 2016 May 4;36(18):5084-93. doi: 10.1523/JNEUROSCI.0258-16.2016.

24.

Clinical Inquiry: Is arthroscopic subacromial decompression effective for shoulder impingement?

Ashbaugh A, Neher JO, Safranek S.

J Fam Pract. 2015 Nov;64(11):732-43. No abstract available.

PMID:
26697537
25.

Borderlands.

Neher JO.

Fam Med. 2015 Nov-Dec;47(10):811-2. No abstract available.

26.

Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease.

Varvel NH, Grathwohl SA, Degenhardt K, Resch C, Bosch A, Jucker M, Neher JJ.

J Exp Med. 2015 Oct 19;212(11):1803-9. doi: 10.1084/jem.20150478. Epub 2015 Oct 12.

27.

The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice.

Brelstaff J, Ossola B, Neher JJ, Klingstedt T, Nilsson KP, Goedert M, Spillantini MG, Tolkovsky AM.

Front Neurosci. 2015 May 29;9:184. doi: 10.3389/fnins.2015.00184. eCollection 2015.

28.

Clinical Inquiry: Do statins increase the risk of developing diabetes?

Parker K, Dohr K, Neher JO, Kelsberg G, St Anna L.

J Fam Pract. 2015 Apr;64(4):245-6. Review.

PMID:
25973456
29.

Clinical Inquiry: What therapies alleviate symptoms of polycystic ovary syndrome?

Moreno LE, Bonnell A, Neher JO, Safranek S.

J Fam Pract. 2015 Apr;64(4):247-9. Review.

PMID:
25973451
30.

FPIN's Clinical Inquiries. Treatments for sciatica.

Stephenson A, Kelsberg G, Neher JO, St Anna L.

Am Fam Physician. 2015 May 1;91(9):612-3, 615A, 615B. No abstract available.

31.

FPIN's Clinical Inquiries. Obesity and joint injuries in children.

Sundin BA, Moreno E, Neher JO, St Anna L.

Am Fam Physician. 2015 Mar 1;91(5):320, 322. No abstract available.

32.

Clinical inquiry: is red-yeast rice a safe and effective alternative to statins?

Chen HH, Neher J, Safranek S.

J Fam Pract. 2015 Feb;64(2):128-35.

PMID:
25671533
33.

Regional distribution of selective neuronal loss and microglial activation across the MCA territory after transient focal ischemia: quantitative versus semiquantitative systematic immunohistochemical assessment.

Emmrich JV, Ejaz S, Neher JJ, Williamson DJ, Baron JC.

J Cereb Blood Flow Metab. 2015 Jan;35(1):20-7. doi: 10.1038/jcbfm.2014.181. Epub 2014 Oct 29.

34.

Cardiovascular effects of NSAIDs.

Sherve K, Gerard CJ, Neher JO, St Anna L.

Am Fam Physician. 2014 Aug 15;90(4):Online. Review. No abstract available.

35.

Clinical inquiry: How do hydrochlorothiazide and chlorthalidone compare for treating hypertension?

Kildare L, Jones T, Neher JO, St Anna L.

J Fam Pract. 2014 Apr;63(4):227-8. Review. No abstract available.

PMID:
24905126
36.

Inhibition of UDP/P2Y6 purinergic signaling prevents phagocytosis of viable neurons by activated microglia in vitro and in vivo.

Neher JJ, Neniskyte U, Hornik T, Brown GC.

Glia. 2014 Sep;62(9):1463-75. doi: 10.1002/glia.22693. Epub 2014 May 19.

37.

Microglial phagocytosis of live neurons.

Brown GC, Neher JJ.

Nat Rev Neurosci. 2014 Apr;15(4):209-16. doi: 10.1038/nrn3710. Review.

PMID:
24646669
38.

Clinical inquiries. What is the best imaging method for patients with a presumed acute stroke?

Sadeghi R, Neher J, Safranek S.

J Fam Pract. 2014 Jan;63(1):36-7. Review. No abstract available. Erratum in: J Fam Pract. 2014 Sep;63(9):492. St. Anna, Leilani [Deleted] and Safranek, Sarah [Added].

PMID:
24475467
39.

Clinical Inquiry: Does metformin prevent diabetes in at-risk adults?

Mangahas T, Huang G, Neher J, Safranek S.

J Fam Pract. 2013 Aug;62(8):436-7. Review. No abstract available.

PMID:
24143338
40.

Phagocytosis executes delayed neuronal death after focal brain ischemia.

Neher JJ, Emmrich JV, Fricker M, Mander PK, Théry C, Brown GC.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):E4098-107. doi: 10.1073/pnas.1308679110. Epub 2013 Oct 7.

41.

Clinical Inquiry. Do dietary choices alone alter the risk of developing metabolic syndrome?

Carey J, Neher J, St Anna L.

J Fam Pract. 2013 Sep;62(9):507-19. No abstract available.

PMID:
24080561
42.

Homeostatic and injury-induced microglia behavior in the aging brain.

Hefendehl JK, Neher JJ, Sühs RB, Kohsaka S, Skodras A, Jucker M.

Aging Cell. 2014 Feb;13(1):60-9. doi: 10.1111/acel.12149. Epub 2013 Sep 18.

43.

Rotenone induces neuronal death by microglial phagocytosis of neurons.

Emmrich JV, Hornik TC, Neher JJ, Brown GC.

FEBS J. 2013 Oct;280(20):5030-8. doi: 10.1111/febs.12401. Epub 2013 Jul 10.

44.

Clinical Inquiry: Do venlafaxine and gabapentin control hot flashes in women with a history of breast cancer?

Sarkissian A, Neher JO, Singh R, St Anna L.

J Fam Pract. 2012 Dec;61(12):759-72. Review.

PMID:
23313996
45.

Probability and the black cloud.

Neher JO.

Fam Med. 2012 Oct;44(9):654-5. No abstract available.

46.

Clinical Inquiry. Multivitamins for healthy children: what are the true benefits?

Schouweiler H, Neher JO, St Anna L.

J Fam Pract. 2012 Aug;61(8):508a-b. Review.

PMID:
22871661
47.

Eaten alive! Cell death by primary phagocytosis: 'phagoptosis'.

Brown GC, Neher JJ.

Trends Biochem Sci. 2012 Aug;37(8):325-32. doi: 10.1016/j.tibs.2012.05.002. Epub 2012 Jun 7. Review.

PMID:
22682109
48.

Clinical Inquiry. What drugs are effective for periodic limb movement disorder?

Lee YA, Huynh P, Neher JO, Safranek S.

J Fam Pract. 2012 May;61(5):296-8. Review. No abstract available.

PMID:
22577635
49.

Clinical Inquiry. Medication vs radioablation for Graves' disease: how do they compare?

Ford J, Neher JO, Safranek S.

J Fam Pract. 2012 May;61(5):294-5. Review. No abstract available.

PMID:
22577634
50.

Clinical Inquiry. How does smoking in the home affect children with asthma?

Neogi T, Neher JO, Safranek S.

J Fam Pract. 2012 May;61(5):292-3. Review. No abstract available.

PMID:
22577633

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