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Items: 30

1.

VOLARE: visual analysis of disease-associated microbiome-immune system interplay.

Siebert JC, Neff CP, Schneider JM, Regner EH, Ohri N, Kuhn KA, Palmer BE, Lozupone CA, Görg C.

BMC Bioinformatics. 2019 Aug 20;20(1):432. doi: 10.1186/s12859-019-3021-0.

2.

Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection.

Li SX, Sen S, Schneider JM, Xiong KN, Nusbacher NM, Moreno-Huizar N, Shaffer M, Armstrong AJS, Severs E, Kuhn K, Neff CP, McCarter M, Campbell T, Lozupone CA, Palmer BE.

PLoS Pathog. 2019 Apr 4;15(4):e1007611. doi: 10.1371/journal.ppat.1007611. eCollection 2019 Apr.

3.

Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function.

Jones D, Como CN, Jing L, Blackmon A, Neff CP, Krueger O, Bubak AN, Palmer BE, Koelle DM, Nagel MA.

PLoS Pathog. 2019 Mar 14;15(3):e1007650. doi: 10.1371/journal.ppat.1007650. eCollection 2019 Mar.

4.

Role for nuclear interleukin-37 in the suppression of innate immunity.

Li S, Amo-Aparicio J, Neff CP, Tengesdal IW, Azam T, Palmer BE, López-Vales R, Bufler P, Dinarello CA.

Proc Natl Acad Sci U S A. 2019 Feb 21. pii: 201821111. doi: 10.1073/pnas.1821111116. [Epub ahead of print]

PMID:
30792349
5.

Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression.

Jin Y, Roberts GHL, Ferrara TM, Ben S, van Geel N, Wolkerstorfer A, Ezzedine K, Siebert J, Neff CP, Palmer BE, Santorico SA, Spritz RA.

Nat Commun. 2019 Jan 23;10(1):391. doi: 10.1038/s41467-019-08337-4.

6.

Upregulation of Chitinase 1 in Alveolar Macrophages of HIV-Infected Smokers.

Logue EC, Neff CP, Mack DG, Martin AK, Fiorillo S, Lavelle J, Vandivier RW, Campbell TB, Palmer BE, Fontenot AP.

J Immunol. 2019 Mar 1;202(5):1363-1372. doi: 10.4049/jimmunol.1801105. Epub 2019 Jan 21.

PMID:
30665939
7.

Fecal Microbiota Composition Drives Immune Activation in HIV-infected Individuals.

Neff CP, Krueger O, Xiong K, Arif S, Nusbacher N, Schneider JM, Cunningham AW, Armstrong A, Li S, McCarter MD, Campbell TB, Lozupone CA, Palmer BE.

EBioMedicine. 2018 Apr;30:192-202. doi: 10.1016/j.ebiom.2018.03.024. Epub 2018 Mar 26.

8.

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.

Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1530-E1539. doi: 10.1073/pnas.1716095115. Epub 2018 Jan 29.

9.

Varicella zoster virus-infected cerebrovascular cells produce a proinflammatory environment.

Jones D, Neff CP, Palmer BE, Stenmark K, Nagel MA.

Neurol Neuroimmunol Neuroinflamm. 2017 Jul 13;4(5):e382. doi: 10.1212/NXI.0000000000000382. eCollection 2017 Sep.

10.

A humanized mouse model for HIV-2 infection and efficacy testing of a single-pill triple-drug combination anti-retroviral therapy.

Hu S, Neff CP, Kumar DM, Habu Y, Akkina SR, Seki T, Akkina R.

Virology. 2017 Jan 15;501:115-118. doi: 10.1016/j.virol.2016.11.013. Epub 2016 Nov 30.

11.

Diverse Intestinal Bacteria Contain Putative Zwitterionic Capsular Polysaccharides with Anti-inflammatory Properties.

Neff CP, Rhodes ME, Arnolds KL, Collins CB, Donnelly J, Nusbacher N, Jedlicka P, Schneider JM, McCarter MD, Shaffer M, Mazmanian SK, Palmer BE, Lozupone CA.

Cell Host Microbe. 2016 Oct 12;20(4):535-547. doi: 10.1016/j.chom.2016.09.002. Epub 2016 Sep 29.

12.

Varicella-Zoster Virus Downregulates Programmed Death Ligand 1 and Major Histocompatibility Complex Class I in Human Brain Vascular Adventitial Fibroblasts, Perineurial Cells, and Lung Fibroblasts.

Jones D, Blackmon A, Neff CP, Palmer BE, Gilden D, Badani H, Nagel MA.

J Virol. 2016 Nov 14;90(23):10527-10534. doi: 10.1128/JVI.01546-16. Print 2016 Dec 1.

13.

Programmed Death 1 Expression on CD4+ T Cells Predicts Mortality after Allogeneic Stem Cell Transplantation.

Schade H, Sen S, Neff CP, Freed BM, Gao D, Gutman JA, Palmer BE.

Biol Blood Marrow Transplant. 2016 Dec;22(12):2172-2179. doi: 10.1016/j.bbmt.2016.08.007. Epub 2016 Aug 9.

14.

Complexities of Gut Microbiome Dysbiosis in the Context of HIV Infection and Antiretroviral Therapy.

Li SX, Armstrong A, Neff CP, Shaffer M, Lozupone CA, Palmer BE.

Clin Pharmacol Ther. 2016 Jun;99(6):600-11. doi: 10.1002/cpt.363. Epub 2016 Apr 16. Review.

15.

MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo.

Cavalli G, Hayashi M, Jin Y, Yorgov D, Santorico SA, Holcomb C, Rastrou M, Erlich H, Tengesdal IW, Dagna L, Neff CP, Palmer BE, Spritz RA, Dinarello CA.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1363-8. doi: 10.1073/pnas.1523482113. Epub 2016 Jan 19.

16.

Correction: PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing.

Akhmetzyanova I, Drabczyk M, Neff CP, Gibbert K, Dietze KK, Werner T, Liu J, Chen L, Lang KS, Palmer BE, Dittmer U, Zelinskyy G.

PLoS Pathog. 2015 Dec 18;11(12):e1005364. doi: 10.1371/journal.ppat.1005364. eCollection 2015 Dec. No abstract available.

17.

PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing.

Akhmetzyanova I, Drabczyk M, Neff CP, Gibbert K, Dietze KK, Werner T, Liu J, Chen L, Lang KS, Palmer BE, Dittmer U, Zelinskyy G.

PLoS Pathog. 2015 Oct 20;11(10):e1005224. doi: 10.1371/journal.ppat.1005224. eCollection 2015 Oct. Erratum in: PLoS Pathog. 2015 Dec;11(12):e1005364.

18.

Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.

Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA.

Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2497-502. doi: 10.1073/pnas.1424626112. Epub 2015 Feb 5.

19.

Lymphocytic alveolitis is associated with the accumulation of functionally impaired HIV-specific T cells in the lung of antiretroviral therapy-naive subjects.

Neff CP, Chain JL, MaWhinney S, Martin AK, Linderman DJ, Flores SC, Campbell TB, Palmer BE, Fontenot AP.

Am J Respir Crit Care Med. 2015 Feb 15;191(4):464-73. doi: 10.1164/rccm.201408-1521OC.

20.

HIV-induced alteration in gut microbiota: driving factors, consequences, and effects of antiretroviral therapy.

Lozupone CA, Rhodes ME, Neff CP, Fontenot AP, Campbell TB, Palmer BE.

Gut Microbes. 2014 Jul 1;5(4):562-70. doi: 10.4161/gmic.32132. Epub 2014 Jul 31. Review.

PMID:
25078714
21.

In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice.

Palmer BE, Neff CP, Lecureux J, Ehler A, Dsouza M, Remling-Mulder L, Korman AJ, Fontenot AP, Akkina R.

J Immunol. 2013 Jan 1;190(1):211-9. doi: 10.4049/jimmunol.1201108. Epub 2012 Dec 3.

22.

Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge.

Zhou J, Neff CP, Swiderski P, Li H, Smith DD, Aboellail T, Remling-Mulder L, Akkina R, Rossi JJ.

Mol Ther. 2013 Jan;21(1):192-200. doi: 10.1038/mt.2012.226. Epub 2012 Nov 20.

23.

Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model.

Veselinovic M, Neff CP, Mulder LR, Akkina R.

Virology. 2012 Oct 25;432(2):505-10. doi: 10.1016/j.virol.2012.06.025. Epub 2012 Jul 24.

24.

Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice.

Zhou J, Neff CP, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, Liang Z, Peng L, Akkina R, Rossi JJ.

Mol Ther. 2011 Dec;19(12):2228-38. doi: 10.1038/mt.2011.207. Epub 2011 Sep 27.

25.

Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes.

Akkina R, Berges BK, Palmer BE, Remling L, Neff CP, Kuruvilla J, Connick E, Folkvord J, Gagliardi K, Kassu A, Akkina SR.

PLoS One. 2011;6(6):e20169. doi: 10.1371/journal.pone.0020169. Epub 2011 Jun 14.

26.

A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice.

Neff CP, Kurisu T, Ndolo T, Fox K, Akkina R.

PLoS One. 2011;6(6):e20209. doi: 10.1371/journal.pone.0020209. Epub 2011 Jun 1.

27.

An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice.

Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, Smith DD, Swiderski P, Rossi JJ, Akkina R.

Sci Transl Med. 2011 Jan 19;3(66):66ra6. doi: 10.1126/scitranslmed.3001581.

28.

Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model.

Neff CP, Ndolo T, Tandon A, Habu Y, Akkina R.

PLoS One. 2010 Dec 21;5(12):e15257. doi: 10.1371/journal.pone.0015257.

29.

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells.

Zhou J, Swiderski P, Li H, Zhang J, Neff CP, Akkina R, Rossi JJ.

Nucleic Acids Res. 2009 May;37(9):3094-109. doi: 10.1093/nar/gkp185. Epub 2009 Mar 21.

30.

The 3' untranslated region of sindbis virus represses deadenylation of viral transcripts in mosquito and Mammalian cells.

Garneau NL, Sokoloski KJ, Opyrchal M, Neff CP, Wilusz CJ, Wilusz J.

J Virol. 2008 Jan;82(2):880-92. Epub 2007 Oct 31.

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