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Items: 1 to 50 of 125

1.

Breast cancer brain metastases show increased levels of genomic aberration based homologous recombination deficiency scores relative to their corresponding primary tumors.

Diossy M, Reiniger L, Sztupinszki Z, Krzystanek M, Timms KM, Neff C, Solimeno C, Pruss D, Eklund AC, Tóth E, Kiss O, Rusz O, Cserni G, Zombori T, Székely B, Tímár J, Csabai I, Szallasi Z.

Ann Oncol. 2018 Jun 18. doi: 10.1093/annonc/mdy216. [Epub ahead of print]

PMID:
29917049
2.

Using the PDQ-39 in routine care for Parkinson's disease.

Neff C, Wang MC, Martel H.

Parkinsonism Relat Disord. 2018 May 17. pii: S1353-8020(18)30251-7. doi: 10.1016/j.parkreldis.2018.05.019. [Epub ahead of print]

PMID:
29853294
3.

Biomarker Assessment of HR Deficiency, Tumor BRCA1/2 Mutations, and CCNE1 Copy Number in Ovarian Cancer: Associations with Clinical Outcome Following Platinum Monotherapy.

Stronach EA, Paul J, Timms KM, Hughes E, Brown K, Neff C, Perry M, Gutin A, El-Bahrawy M, Steel JH, Liu X, Lewsley LA, Siddiqui N, Gabra H, Lanchbury JS, Brown R.

Mol Cancer Res. 2018 Jul;16(7):1103-1111. doi: 10.1158/1541-7786.MCR-18-0034. Epub 2018 May 3.

PMID:
29724815
4.

Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects.

Sonntag KC, Song B, Lee N, Jung JH, Cha Y, Leblanc P, Neff C, Kong SW, Carter BS, Schweitzer J, Kim KS.

Prog Neurobiol. 2018 Apr 11. pii: S0301-0082(17)30104-1. doi: 10.1016/j.pneurobio.2018.04.005. [Epub ahead of print] Review.

PMID:
29653250
5.

Fecal Microbiota Composition Drives Immune Activation in HIV-infected Individuals.

Neff CP, Krueger O, Xiong K, Arif S, Nusbacher N, Schneider JM, Cunningham AW, Armstrong A, Li S, McCarter MD, Campbell TB, Lozupone CA, Palmer BE.

EBioMedicine. 2018 Apr;30:192-202. doi: 10.1016/j.ebiom.2018.03.024. Epub 2018 Mar 26.

6.

Associations between anxiolytic medications and ventral hernia repair.

Neff C, Totten C, Plymale M, Oyler DR, Davenport D, Roth JS.

Hernia. 2018 Mar 28. doi: 10.1007/s10029-018-1766-4. [Epub ahead of print]

PMID:
29594842
7.

Binding Specificities of Nanobody•Membrane Protein Complexes Obtained from Chemical Cross-Linking and High-Mass MALDI Mass Spectrometry.

Köhler M, Neff C, Perez C, Brunner C, Pardon E, Steyaert J, Schneider G, Locher KP, Zenobi R.

Anal Chem. 2018 Apr 17;90(8):5306-5313. doi: 10.1021/acs.analchem.8b00236. Epub 2018 Apr 4.

PMID:
29562137
8.

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.

Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1530-E1539. doi: 10.1073/pnas.1716095115. Epub 2018 Jan 29.

9.

Homologous recombination deficiency (HRD) status predicts response to standard neoadjuvant chemotherapy in patients with triple-negative or BRCA1/2 mutation-associated breast cancer.

Telli ML, Hellyer J, Audeh W, Jensen KC, Bose S, Timms KM, Gutin A, Abkevich V, Peterson RN, Neff C, Hughes E, Sangale Z, Jones J, Hartman AR, Chang PJ, Vinayak S, Wenstrup R, Ford JM.

Breast Cancer Res Treat. 2018 Apr;168(3):625-630. doi: 10.1007/s10549-017-4624-7. Epub 2017 Dec 23.

PMID:
29275435
10.

Varicella zoster virus-infected cerebrovascular cells produce a proinflammatory environment.

Jones D, Neff CP, Palmer BE, Stenmark K, Nagel MA.

Neurol Neuroimmunol Neuroinflamm. 2017 Jul 13;4(5):e382. doi: 10.1212/NXI.0000000000000382. eCollection 2017 Sep.

11.

Social considerations of inflammatory bowel disease in Southern Israel.

Taylor J, Neff C.

BMJ Case Rep. 2017 Jul 17;2017. pii: bcr-2017-219941. doi: 10.1136/bcr-2017-219941.

PMID:
28716774
12.

A humanized mouse model for HIV-2 infection and efficacy testing of a single-pill triple-drug combination anti-retroviral therapy.

Hu S, Neff CP, Kumar DM, Habu Y, Akkina SR, Seki T, Akkina R.

Virology. 2017 Jan 15;501:115-118. doi: 10.1016/j.virol.2016.11.013. Epub 2016 Nov 30.

13.

Diverse Intestinal Bacteria Contain Putative Zwitterionic Capsular Polysaccharides with Anti-inflammatory Properties.

Neff CP, Rhodes ME, Arnolds KL, Collins CB, Donnelly J, Nusbacher N, Jedlicka P, Schneider JM, McCarter MD, Shaffer M, Mazmanian SK, Palmer BE, Lozupone CA.

Cell Host Microbe. 2016 Oct 12;20(4):535-547. doi: 10.1016/j.chom.2016.09.002. Epub 2016 Sep 29.

14.
15.

Intratumor Heterogeneity of Homologous Recombination Deficiency in Primary Breast Cancer.

von Wahlde MK, Timms KM, Chagpar A, Wali VB, Jiang T, Bossuyt V, Saglam O, Reid J, Gutin A, Neff C, Lanchbury JS, Hatzis C, Hofstatter E, Pusztai L.

Clin Cancer Res. 2017 Mar 1;23(5):1193-1199. doi: 10.1158/1078-0432.CCR-16-0889. Epub 2016 Sep 6.

16.

Programmed Death 1 Expression on CD4+ T Cells Predicts Mortality after Allogeneic Stem Cell Transplantation.

Schade H, Sen S, Neff CP, Freed BM, Gao D, Gutman JA, Palmer BE.

Biol Blood Marrow Transplant. 2016 Dec;22(12):2172-2179. doi: 10.1016/j.bbmt.2016.08.007. Epub 2016 Aug 9.

17.

STUDIES OF MOLECULAR CHANGES IN INTERVERTEBRAL DISC DEGENERATION IN ANIMAL MODEL.

de Campos MF, de Oliveira CP, Neff CB, Correa OM, Pinhal MA, Rodrigues LM.

Acta Ortop Bras. 2016 Jan-Feb;24(1):16-21. doi: 10.1590/1413-785220162401152960.

18.

Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer.

Telli ML, Timms KM, Reid J, Hennessy B, Mills GB, Jensen KC, Szallasi Z, Barry WT, Winer EP, Tung NM, Isakoff SJ, Ryan PD, Greene-Colozzi A, Gutin A, Sangale Z, Iliev D, Neff C, Abkevich V, Jones JT, Lanchbury JS, Hartman AR, Garber JE, Ford JM, Silver DP, Richardson AL.

Clin Cancer Res. 2016 Aug 1;22(15):3764-73. doi: 10.1158/1078-0432.CCR-15-2477. Epub 2016 Mar 8.

19.

Complexities of Gut Microbiome Dysbiosis in the Context of HIV Infection and Antiretroviral Therapy.

Li SX, Armstrong A, Neff CP, Shaffer M, Lozupone CA, Palmer BE.

Clin Pharmacol Ther. 2016 Jun;99(6):600-11. doi: 10.1002/cpt.363. Epub 2016 Apr 16. Review.

20.

MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo.

Cavalli G, Hayashi M, Jin Y, Yorgov D, Santorico SA, Holcomb C, Rastrou M, Erlich H, Tengesdal IW, Dagna L, Neff CP, Palmer BE, Spritz RA, Dinarello CA.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1363-8. doi: 10.1073/pnas.1523482113. Epub 2016 Jan 19.

21.

Correction: PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing.

Akhmetzyanova I, Drabczyk M, Neff CP, Gibbert K, Dietze KK, Werner T, Liu J, Chen L, Lang KS, Palmer BE, Dittmer U, Zelinskyy G.

PLoS Pathog. 2015 Dec 18;11(12):e1005364. doi: 10.1371/journal.ppat.1005364. eCollection 2015 Dec. No abstract available.

22.

PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing.

Akhmetzyanova I, Drabczyk M, Neff CP, Gibbert K, Dietze KK, Werner T, Liu J, Chen L, Lang KS, Palmer BE, Dittmer U, Zelinskyy G.

PLoS Pathog. 2015 Oct 20;11(10):e1005224. doi: 10.1371/journal.ppat.1005224. eCollection 2015 Oct. Erratum in: PLoS Pathog. 2015 Dec;11(12):e1005364.

23.

FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice.

Stemmer K, Zani F, Habegger KM, Neff C, Kotzbeck P, Bauer M, Yalamanchilli S, Azad A, Lehti M, Martins PJ, Müller TD, Pfluger PT, Seeley RJ.

Diabetologia. 2015 Oct;58(10):2414-23. doi: 10.1007/s00125-015-3668-7. Epub 2015 Jun 23.

24.

Auxin Import and Local Auxin Biosynthesis Are Required for Mitotic Divisions, Cell Expansion and Cell Specification during Female Gametophyte Development in Arabidopsis thaliana.

Panoli A, Martin MV, Alandete-Saez M, Simon M, Neff C, Swarup R, Bellido A, Yuan L, Pagnussat GC, Sundaresan V.

PLoS One. 2015 May 13;10(5):e0126164. doi: 10.1371/journal.pone.0126164. eCollection 2015.

25.

Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.

Li S, Neff CP, Barber K, Hong J, Luo Y, Azam T, Palmer BE, Fujita M, Garlanda C, Mantovani A, Kim S, Dinarello CA.

Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2497-502. doi: 10.1073/pnas.1424626112. Epub 2015 Feb 5.

26.

Lymphocytic alveolitis is associated with the accumulation of functionally impaired HIV-specific T cells in the lung of antiretroviral therapy-naive subjects.

Neff CP, Chain JL, MaWhinney S, Martin AK, Linderman DJ, Flores SC, Campbell TB, Palmer BE, Fontenot AP.

Am J Respir Crit Care Med. 2015 Feb 15;191(4):464-73. doi: 10.1164/rccm.201408-1521OC.

27.

Association of BRCA1/2 defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes.

Timms KM, Abkevich V, Hughes E, Neff C, Reid J, Morris B, Kalva S, Potter J, Tran TV, Chen J, Iliev D, Sangale Z, Tikishvili E, Perry M, Zharkikh A, Gutin A, Lanchbury JS.

Breast Cancer Res. 2014 Dec 5;16(6):475. doi: 10.1186/s13058-014-0475-x.

28.

Thermoneutral housing is a critical factor for immune function and diet-induced obesity in C57BL/6 nude mice.

Stemmer K, Kotzbeck P, Zani F, Bauer M, Neff C, Müller TD, Pfluger PT, Seeley RJ, Divanovic S.

Int J Obes (Lond). 2015 May;39(5):791-7. doi: 10.1038/ijo.2014.187. Epub 2014 Oct 28.

29.

HIV-induced alteration in gut microbiota: driving factors, consequences, and effects of antiretroviral therapy.

Lozupone CA, Rhodes ME, Neff CP, Fontenot AP, Campbell TB, Palmer BE.

Gut Microbes. 2014 Jul 1;5(4):562-70. doi: 10.4161/gmic.32132. Epub 2014 Jul 31. Review.

PMID:
25078714
30.

Roux-en-Y gastric bypass surgery but not vertical sleeve gastrectomy decreases bone mass in male rats.

Stemmer K, Bielohuby M, Grayson BE, Begg DP, Chambers AP, Neff C, Woods SC, Erben RG, Tschöp MH, Bidlingmaier M, Clemens TL, Seeley RJ.

Endocrinology. 2013 Jun;154(6):2015-24. doi: 10.1210/en.2012-2130. Epub 2013 Apr 3. Erratum in: Endocrinology. 2016 May;157(5):2196.

31.

The rise of repeal: policy entrepreneurship and Don't Ask, Don't Tell.

Neff CL, Edgell LR.

J Homosex. 2013;60(2-3):232-49. doi: 10.1080/00918369.2013.744669.

PMID:
23414271
32.

In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice.

Palmer BE, Neff CP, Lecureux J, Ehler A, Dsouza M, Remling-Mulder L, Korman AJ, Fontenot AP, Akkina R.

J Immunol. 2013 Jan 1;190(1):211-9. doi: 10.4049/jimmunol.1201108. Epub 2012 Dec 3.

33.

Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge.

Zhou J, Neff CP, Swiderski P, Li H, Smith DD, Aboellail T, Remling-Mulder L, Akkina R, Rossi JJ.

Mol Ther. 2013 Jan;21(1):192-200. doi: 10.1038/mt.2012.226. Epub 2012 Nov 20.

34.

Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model.

Veselinovic M, Neff CP, Mulder LR, Akkina R.

Virology. 2012 Oct 25;432(2):505-10. doi: 10.1016/j.virol.2012.06.025. Epub 2012 Jul 24.

35.

Glycosiderophores: synthesis of tris-hydroxamate siderophores based on a galactose or glycero central scaffold, Fe(III) complexation studies.

Neff C, Bellot F, Waern JB, Lambert F, Brandel J, Serratrice G, Gaboriau F, Policar C.

J Inorg Biochem. 2012 Jul;112:59-67. doi: 10.1016/j.jinorgbio.2012.02.030. Epub 2012 Mar 7.

PMID:
22551986
36.

Father involvement, paternal sensitivity, and father-child attachment security in the first 3 years.

Brown GL, Mangelsdorf SC, Neff C.

J Fam Psychol. 2012 Jun;26(3):421-30. doi: 10.1037/a0027836. Epub 2012 Apr 2.

37.

Pancreatic islet allograft in spleen with immunosuppression with cyclosporine. Experimental model in dogs.

Waisberg J, Neff CB, Waisberg DR, Germini D, Gonçalves JE, Zanotto A, Speranzini MB.

Acta Cir Bras. 2011;26 Suppl 2:57-64.

38.

Comparison of uniatrial and biatrial radiofrequency ablation procedures in atrial fibrillation: initial results.

Breda JR, Breda AS, Ragognette RG, Machado LN, Neff CB, de Matos LL, Meneghine A, Pires AC.

Heart Surg Forum. 2011 Oct;14(5):E271-5. doi: 10.1532/HSF98.20101119.

PMID:
21997647
39.

Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice.

Zhou J, Neff CP, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, Liang Z, Peng L, Akkina R, Rossi JJ.

Mol Ther. 2011 Dec;19(12):2228-38. doi: 10.1038/mt.2011.207. Epub 2011 Sep 27.

40.

The role of the Toronto Girls' Home, 1863-1910.

Neff C.

J Fam Hist. 2011;36(3):286-315.

PMID:
21898964
41.

Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes.

Akkina R, Berges BK, Palmer BE, Remling L, Neff CP, Kuruvilla J, Connick E, Folkvord J, Gagliardi K, Kassu A, Akkina SR.

PLoS One. 2011;6(6):e20169. doi: 10.1371/journal.pone.0020169. Epub 2011 Jun 14.

42.

A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice.

Neff CP, Kurisu T, Ndolo T, Fox K, Akkina R.

PLoS One. 2011;6(6):e20209. doi: 10.1371/journal.pone.0020209. Epub 2011 Jun 1.

43.

An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice.

Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, Smith DD, Swiderski P, Rossi JJ, Akkina R.

Sci Transl Med. 2011 Jan 19;3(66):66ra6. doi: 10.1126/scitranslmed.3001581.

44.

Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model.

Neff CP, Ndolo T, Tandon A, Habu Y, Akkina R.

PLoS One. 2010 Dec 21;5(12):e15257. doi: 10.1371/journal.pone.0015257.

45.

The human-bacterial pathogen protein interaction networks of Bacillus anthracis, Francisella tularensis, and Yersinia pestis.

Dyer MD, Neff C, Dufford M, Rivera CG, Shattuck D, Bassaganya-Riera J, Murali TM, Sobral BW.

PLoS One. 2010 Aug 9;5(8):e12089. doi: 10.1371/journal.pone.0012089.

46.

Oxidative stress and endothelial dysfunction in aortas of aged spontaneously hypertensive rats by NOX1/2 is reversed by NADPH oxidase inhibition.

Wind S, Beuerlein K, Armitage ME, Taye A, Kumar AH, Janowitz D, Neff C, Shah AM, Wingler K, Schmidt HH.

Hypertension. 2010 Sep;56(3):490-7. doi: 10.1161/HYPERTENSIONAHA.109.149187. Epub 2010 Jul 6.

47.

Observed and Reported Supportive Coparenting as Predictors of Infant-Mother and Infant-Father Attachment Security.

Brown GL, Schoppe-Sullivan SJ, Mangelsdorf SC, Neff C.

Early Child Dev Care. 2010;180(1-2):121-137.

48.

Parental beliefs, infant temperament, and marital quality: associations with infant-mother and infant-father attachment.

Wong MS, Mangelsdorf SC, Brown GL, Neff C, Schoppe-Sullivan SJ.

J Fam Psychol. 2009 Dec;23(6):828-38. doi: 10.1037/a0016491.

49.

Suggestive evidence on chromosomes 2 and 19 for HTR1A-independent linkage of genes to major depression.

Abkevich V, Neff CD, Potter J, Riley R, Shattuck D, Katz DA.

Neurogenetics. 2010 May;11(2):271-2. doi: 10.1007/s10048-009-0222-0. Epub 2009 Oct 8. No abstract available.

PMID:
19813033
50.

The myxoma virus m-t5 ankyrin repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cells.

Werden SJ, Lanchbury J, Shattuck D, Neff C, Dufford M, McFadden G.

J Virol. 2009 Dec;83(23):12068-83. doi: 10.1128/JVI.00963-09. Epub 2009 Sep 23.

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