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Turbulent Flow Promotes Cleavage of VWF (von Willebrand Factor) by ADAMTS13 (A Disintegrin and Metalloproteinase With a Thrombospondin Type-1 Motif, Member 13).

Bortot M, Ashworth K, Sharifi A, Walker F, Crawford NC, Neeves KB, Bark D Jr, Di Paola J.

Arterioscler Thromb Vasc Biol. 2019 Jul 11:ATVBAHA119312814. doi: 10.1161/ATVBAHA.119.312814. [Epub ahead of print]


ac/dc Magnetic Fields for Enhanced Translation of Colloidal Microwheels.

Disharoon D, Neeves KB, Marr DWM.

Langmuir. 2019 Mar 5;35(9):3455-3460. doi: 10.1021/acs.langmuir.8b04084. Epub 2019 Feb 19.


A local and global sensitivity analysis of a mathematical model of coagulation and platelet deposition under flow.

Link KG, Stobb MT, Di Paola J, Neeves KB, Fogelson AL, Sindi SS, Leiderman K.

PLoS One. 2018 Jul 26;13(7):e0200917. doi: 10.1371/journal.pone.0200917. eCollection 2018.


Platelets Drive Thrombus Propagation in a Hematocrit and Glycoprotein VI-Dependent Manner in an In Vitro Venous Thrombosis Model.

Lehmann M, Schoeman RM, Krohl PJ, Wallbank AM, Samaniuk JR, Jandrot-Perrus M, Neeves KB.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1052-1062. doi: 10.1161/ATVBAHA.118.310731. Epub 2018 Feb 22.


Evaluation of a microfluidic flow assay to screen for von Willebrand disease and low von Willebrand factor levels.

Lehmann M, Ashworth K, Manco-Johnson M, Di Paola J, Neeves KB, Ng CJ.

J Thromb Haemost. 2018 Jan;16(1):104-115. doi: 10.1111/jth.13881. Epub 2017 Nov 23.


The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis.

Branchford BR, Stalker TJ, Law L, Acevedo G, Sather S, Brzezinski C, Wilson KM, Minson K, Lee-Sherick AB, Davizon-Castillo P, Ng C, Zhang W, Neeves KB, Lentz SR, Wang X, Frye SV, Shelton Earp H 3rd, DeRyckere D, Brass LF, Graham DK, Di Paola JA.

J Thromb Haemost. 2018 Feb;16(2):352-363. doi: 10.1111/jth.13875. Epub 2018 Jan 12.


Enhanced Fibrinolysis with Magnetically Powered Colloidal Microwheels.

Tasci TO, Disharoon D, Schoeman RM, Rana K, Herson PS, Marr DWM, Neeves KB.

Small. 2017 Sep;13(36). doi: 10.1002/smll.201700954. Epub 2017 Jul 18.


Flow chamber and microfluidic approaches for measuring thrombus formation in genetic bleeding disorders.

Schoeman RM, Lehmann M, Neeves KB.

Platelets. 2017 Jul;28(5):463-471. doi: 10.1080/09537104.2017.1306042. Epub 2017 May 22. Review.


A microfluidic model of hemostasis sensitive to platelet function and coagulation.

Schoeman RM, Rana K, Danes N, Lehmann M, Di Paola JA, Fogelson AL, Leiderman K, Neeves KB.

Cell Mol Bioeng. 2017 Feb;10(1):3-15. doi: 10.1007/s12195-016-0469-0. Epub 2016 Oct 24.


Magnetic Microlassos for Reversible Cargo Capture, Transport, and Release.

Yang T, Tasci TO, Neeves KB, Wu N, Marr DWM.

Langmuir. 2017 Jun 13;33(23):5932-5937. doi: 10.1021/acs.langmuir.7b00357. Epub 2017 Mar 27.


Elevated hematocrit enhances platelet accumulation following vascular injury.

Walton BL, Lehmann M, Skorczewski T, Holle LA, Beckman JD, Cribb JA, Mooberry MJ, Wufsus AR, Cooley BC, Homeister JW, Pawlinski R, Falvo MR, Key NS, Fogelson AL, Neeves KB, Wolberg AS.

Blood. 2017 May 4;129(18):2537-2546. doi: 10.1182/blood-2016-10-746479. Epub 2017 Mar 1.


Ask1 regulates murine platelet granule secretion, thromboxane A2 generation, and thrombus formation.

Naik MU, Patel P, Derstine R, Turaga R, Chen X, Golla K, Neeves KB, Ichijo H, Naik UP.

Blood. 2017 Mar 2;129(9):1197-1209. doi: 10.1182/blood-2016-07-729780. Epub 2016 Dec 27.


Non reciprocal skewed rolling of a colloidal wheel due to induced chirality.

Maier FJ, Lachner T, Vilfan A, Tasci TO, Neeves KB, Marr DW, Fischer TM.

Soft Matter. 2016 Nov 23;12(46):9314-9320.


Bead-Based Microfluidic Sediment Analogues: Fabrication and Colloid Transport.

Guo Y, Huang J, Xiao F, Yin X, Chun J, Um W, Neeves KB, Wu N.

Langmuir. 2016 Sep 13;32(36):9342-50. doi: 10.1021/acs.langmuir.6b02184. Epub 2016 Sep 1.


Blood flow and mass transfer regulation of coagulation.

Rana K, Neeves KB.

Blood Rev. 2016 Sep;30(5):357-68. doi: 10.1016/j.blre.2016.04.004. Epub 2016 Apr 29. Review.


Dimensional analysis and scaling relevant to flow models of thrombus formation: communication from the SSC of the ISTH.

McCarty OJ, Ku D, Sugimoto M, King MR, Cosemans JM, Neeves KB; Subcommittee on Biorheology.

J Thromb Haemost. 2016 Mar;14(3):619-22. doi: 10.1111/jth.13241. Epub 2016 Feb 16. No abstract available.


Surface-enabled propulsion and control of colloidal microwheels.

Tasci TO, Herson PS, Neeves KB, Marr DW.

Nat Commun. 2016 Jan 4;7:10225. doi: 10.1038/ncomms10225.


On-chip recalcification of citrated whole blood using a microfluidic herringbone mixer.

Lehmann M, Wallbank AM, Dennis KA, Wufsus AR, Davis KM, Rana K, Neeves KB.

Biomicrofluidics. 2015 Nov 18;9(6):064106. doi: 10.1063/1.4935863. eCollection 2015 Nov.


In microfluidico: Recreating in vivo hemodynamics using miniaturized devices.

Zhu S, Herbig BA, Li R, Colace TV, Muthard RW, Neeves KB, Diamond SL.

Biorheology. 2015;52(5-6):303-18. doi: 10.3233/BIR-15065. Review.


High-throughput linear optical stretcher for mechanical characterization of blood cells.

Roth KB, Neeves KB, Squier J, Marr DW.

Cytometry A. 2016 Apr;89(4):391-7. doi: 10.1002/cyto.a.22794. Epub 2015 Nov 13.


Physiochemical artifacts in FeCl3 thrombosis models.

Neeves KB.

Blood. 2015 Aug 6;126(6):700-1. doi: 10.1182/blood-2015-05-644708.


Fluid Mechanics of Blood Clot Formation.

Fogelson AL, Neeves KB.

Annu Rev Fluid Mech. 2015 Jan 1;47:377-403.


A vascular injury model using focal heat-induced activation of endothelial cells.

Sylman JL, Artzer DT, Rana K, Neeves KB.

Integr Biol (Camb). 2015 Jul;7(7):801-14. doi: 10.1039/c5ib00108k.


Microfluidic technology as an emerging clinical tool to evaluate thrombosis and hemostasis.

Branchford BR, Ng CJ, Neeves KB, Di Paola J.

Thromb Res. 2015 Jul;136(1):13-9. doi: 10.1016/j.thromres.2015.05.012. Epub 2015 May 21. Review.


Imaging of a linear diode bar for an optical cell stretcher.

Roth KB, Neeves KB, Squier J, Marr DW.

Biomed Opt Express. 2015 Feb 11;6(3):807-14. doi: 10.1364/BOE.6.000807. eCollection 2015 Mar 1.


Platelet bioreactor-on-a-chip.

Thon JN, Mazutis L, Wu S, Sylman JL, Ehrlicher A, Machlus KR, Feng Q, Lu S, Lanza R, Neeves KB, Weitz DA, Italiano JE Jr.

Blood. 2014 Sep 18;124(12):1857-67.


Elastic behavior and platelet retraction in low- and high-density fibrin gels.

Wufsus AR, Rana K, Brown A, Dorgan JR, Liberatore MW, Neeves KB.

Biophys J. 2015 Jan 6;108(1):173-83. doi: 10.1016/j.bpj.2014.11.007.


Down in a hole: a new laser ablation model of hemostasis.

Neeves KB.

J Thromb Haemost. 2015 Mar;13(3):414-6. doi: 10.1111/jth.12820. Epub 2015 Jan 9. No abstract available.


A combined microfluidic-microstencil method for patterning biomolecules and cells.

Rana K, Timmer BJ, Neeves KB.

Biomicrofluidics. 2014 Sep 19;8(5):056502. doi: 10.1063/1.4896231. eCollection 2014 Sep.


In vitro cell culture model for toxic inhaled chemical testing.

Ahmad S, Ahmad A, Neeves KB, Hendry-Hofer T, Loader JE, White CW, Veress L.

J Vis Exp. 2014 May 8;(87). doi: 10.3791/51539.


Thrombin generation and fibrin formation under flow on biomimetic tissue factor-rich surfaces.

Onasoga-Jarvis AA, Puls TJ, O'Brien SK, Kuang L, Liang HJ, Neeves KB.

J Thromb Haemost. 2014;12(3):373-82. doi: 10.1111/jth.12491.


Flow-dependent thrombin and fibrin generation in vitro: opportunities for standardization: communication from SSC of the ISTH.

Neeves KB, McCarty OJ, Reininger AJ, Sugimoto M, King MR; Biorheology Subcommittee of the SSC of the ISTH.

J Thromb Haemost. 2014;12(3):418-20. doi: 10.1111/jth.12482. No abstract available.


The effect of factor VIII deficiencies and replacement and bypass therapies on thrombus formation under venous flow conditions in microfluidic and computational models.

Onasoga-Jarvis AA, Leiderman K, Fogelson AL, Wang M, Manco-Johnson MJ, Di Paola JA, Neeves KB.

PLoS One. 2013 Nov 13;8(11):e78732. doi: 10.1371/journal.pone.0078732. eCollection 2013.


The use of microfluidics in hemostasis: clinical diagnostics and biomimetic models of vascular injury.

Neeves KB, Onasoga AA, Wufsus AR.

Curr Opin Hematol. 2013 Sep;20(5):417-23. doi: 10.1097/MOH.0b013e3283642186. Review.


The hydraulic permeability of blood clots as a function of fibrin and platelet density.

Wufsus AR, Macera NE, Neeves KB.

Biophys J. 2013 Apr 16;104(8):1812-23. doi: 10.1016/j.bpj.2013.02.055.


Transport limitations of nitric oxide inhibition of platelet aggregation under flow.

Sylman JL, Lantvit SM, Vedepo MC, Reynolds MM, Neeves KB.

Ann Biomed Eng. 2013 Oct;41(10):2193-205. doi: 10.1007/s10439-013-0803-9. Epub 2013 Apr 6.


Measuring cell mechanics by optical alignment compression cytometry.

Roth KB, Eggleton CD, Neeves KB, Marr DW.

Lab Chip. 2013 Apr 21;13(8):1571-7. doi: 10.1039/c3lc41253a.


Optic imaging of single and two-phase pressure-driven flows in nano-scale channels.

Wu Q, Ok JT, Sun Y, Retterer ST, Neeves KB, Yin X, Bai B, Ma Y.

Lab Chip. 2013 Mar 21;13(6):1165-71. doi: 10.1039/c2lc41259d.


Sources of variability in platelet accumulation on type 1 fibrillar collagen in microfluidic flow assays.

Neeves KB, Onasoga AA, Hansen RR, Lilly JJ, Venckunaite D, Sumner MB, Irish AT, Brodsky G, Manco-Johnson MJ, Di Paola JA.

PLoS One. 2013;8(1):e54680. doi: 10.1371/journal.pone.0054680. Epub 2013 Jan 23.


Collagen-induced thrombosis in large vessels using native prothrombotic substrates.

Neeves KB.

Thromb Res. 2013 Jan;131(1):1-2. doi: 10.1016/j.thromres.2012.11.007. Epub 2012 Nov 20. No abstract available.


Tissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2.

Ahmad S, Ahmad A, Rancourt RC, Neeves KB, Loader JE, Hendry-Hofer T, Di Paola J, Reynolds SD, White CW.

Am J Respir Cell Mol Biol. 2013 Jan;48(1):94-104. doi: 10.1165/rcmb.2012-0189OC. Epub 2012 Oct 11.


High content evaluation of shear dependent platelet function in a microfluidic flow assay.

Hansen RR, Wufsus AR, Barton ST, Onasoga AA, Johnson-Paben RM, Neeves KB.

Ann Biomed Eng. 2013 Feb;41(2):250-62. doi: 10.1007/s10439-012-0658-5. Epub 2012 Sep 22.


Effect of viscoelasticity on the analysis of single-molecule force spectroscopy on live cells.

Gupta VK, Neeves KB, Eggleton CD.

Biophys J. 2012 Jul 3;103(1):137-45. doi: 10.1016/j.bpj.2012.05.044.


Catch me if you can: isolating circulating tumor cells from flowing blood.

Neeves KB.

Clin Chem. 2012 May;58(5):803-4. doi: 10.1373/clinchem.2012.182600. Epub 2012 Feb 21. No abstract available.


Single- and two-phase flow in microfluidic porous media analogs based on Voronoi tessellation.

Wu M, Xiao F, Johnson-Paben RM, Retterer ST, Yin X, Neeves KB.

Lab Chip. 2012 Jan 21;12(2):253-61. doi: 10.1039/c1lc20838a. Epub 2011 Nov 17.


Real-time imaging of perivascular transport of nanoparticles during convection-enhanced delivery in the rat cortex.

Foley CP, Nishimura N, Neeves KB, Schaffer CB, Olbricht WL.

Ann Biomed Eng. 2012 Feb;40(2):292-303. doi: 10.1007/s10439-011-0440-0. Epub 2011 Oct 19.


Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure.

Ahmad S, Raemy DO, Loader JE, Kailey JM, Neeves KB, White CW, Ahmad A, Gehr P, Rothen-Rutishauser BM.

J Aerosol Med Pulm Drug Deliv. 2012 Feb;25(1):7-15. doi: 10.1089/jamp.2011.0889. Epub 2011 Oct 18.


Characterization of collagen thin films for von Willebrand factor binding and platelet adhesion.

Hansen RR, Tipnis AA, White-Adams TC, Di Paola JA, Neeves KB.

Langmuir. 2011 Nov 15;27(22):13648-58. doi: 10.1021/la2023727. Epub 2011 Oct 19.


Microfluidic probes in the treatment of brain-related diseases.

Olbricht WL, Neeves KB, Foley CP.

Drug News Perspect. 2010 Oct;23(8):491-7. doi: 10.1358/dnp.2010.23.8.1489887. Review.


Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D.

Wannemacher KM, Zhu L, Jiang H, Fong KP, Stalker TJ, Lee D, Tran AN, Neeves KB, Maloney S, Kumanogoh A, Kikutani H, Hammer DA, Diamond SL, Brass LF.

Blood. 2010 Dec 16;116(25):5707-15. doi: 10.1182/blood-2010-04-279943. Epub 2010 Sep 20.

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