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Detection of RNA modifications by HPLC analysis and competitive ELISA.

Nees G, Kaufmann A, Bauer S.

Methods Mol Biol. 2014;1169:3-14. doi: 10.1007/978-1-4939-0882-0_1.


TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification.

Oldenburg M, Krüger A, Ferstl R, Kaufmann A, Nees G, Sigmund A, Bathke B, Lauterbach H, Suter M, Dreher S, Koedel U, Akira S, Kawai T, Buer J, Wagner H, Bauer S, Hochrein H, Kirschning CJ.

Science. 2012 Aug 31;337(6098):1111-5. doi: 10.1126/science.1220363. Epub 2012 Jul 19.


The 2'-O-methylation status of a single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition.

Jöckel S, Nees G, Sommer R, Zhao Y, Cherkasov D, Hori H, Ehm G, Schnare M, Nain M, Kaufmann A, Bauer S.

J Exp Med. 2012 Feb 13;209(2):235-41. doi: 10.1084/jem.20111075. Epub 2012 Feb 6.

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