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Items: 18

1.

Myeloid Kdm6b deficiency results in advanced atherosclerosis.

Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen CPPA, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ.

Atherosclerosis. 2018 Aug;275:156-165. doi: 10.1016/j.atherosclerosis.2018.05.052. Epub 2018 Jun 1.

2.

Repressing the repressor: Ezh2 mediates macrophage activation.

Neele AE, de Winther MPJ.

J Exp Med. 2018 May 7;215(5):1269-1271. doi: 10.1084/jem.20180479. Epub 2018 Apr 24.

PMID:
29691302
3.

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets.

van der Tuin SJL, Li Z, Berbée JFP, Verkouter I, Ringnalda LE, Neele AE, van Klinken JB, Rensen SS, Fu J, de Winther MPJ, Groen AK, Rensen PCN, Willems van Dijk K, Wang Y.

J Am Heart Assoc. 2018 Mar 10;7(6). pii: e008105. doi: 10.1161/JAHA.117.008105.

4.

High miR-124-3p expression identifies smoking individuals susceptible to atherosclerosis.

de Ronde MWJ, Kok MGM, Moerland PD, Van den Bossche J, Neele AE, Halliani A, van der Made I, de Winther MPJ, Meijers JCM, Creemers EE, Pinto-Sietsma SJ.

Atherosclerosis. 2017 Aug;263:377-384. doi: 10.1016/j.atherosclerosis.2017.03.045. Epub 2017 Apr 5.

5.

PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia.

Bernelot Moens SJ, Neele AE, Kroon J, van der Valk FM, Van den Bossche J, Hoeksema MA, Hoogeveen RM, Schnitzler JG, Baccara-Dinet MT, Manvelian G, de Winther MPJ, Stroes ESG.

Eur Heart J. 2017 May 21;38(20):1584-1593. doi: 10.1093/eurheartj/ehx002.

PMID:
28329114
6.

Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells.

Neele AE, Prange KH, Hoeksema MA, van der Velden S, Lucas T, Dimmeler S, Lutgens E, Van den Bossche J, de Winther MP.

Epigenomics. 2017 Apr;9(4):383-391. doi: 10.2217/epi-2016-0152. Epub 2017 Mar 21.

PMID:
28322580
7.

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.

Van den Bossche J, Baardman J, Otto NA, van der Velden S, Neele AE, van den Berg SM, Luque-Martin R, Chen HJ, Boshuizen MC, Ahmed M, Hoeksema MA, de Vos AF, de Winther MP.

Cell Rep. 2016 Oct 11;17(3):684-696. doi: 10.1016/j.celrep.2016.09.008.

8.

Myeloid interferon-γ receptor deficiency does not affect atherosclerosis in LDLR(-/-) mice.

Boshuizen MC, Neele AE, Gijbels MJ, van der Velden S, Hoeksema MA, Forman RA, Muller W, Van den Bossche J, de Winther MP.

Atherosclerosis. 2016 Mar;246:325-33. doi: 10.1016/j.atherosclerosis.2016.01.026. Epub 2016 Jan 19.

PMID:
26828750
9.

Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms.

Boshuizen MC, Hoeksema MA, Neele AE, van der Velden S, Hamers AA, Van den Bossche J, Lutgens E, de Winther MP.

Cytokine. 2016 Jan;77:220-6. doi: 10.1016/j.cyto.2015.09.016. Epub 2015 Oct 1.

PMID:
26427927
10.

Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis.

Neele AE, Van den Bossche J, Hoeksema MA, de Winther MP.

Eur J Pharmacol. 2015 Sep 15;763(Pt A):79-89. doi: 10.1016/j.ejphar.2015.03.101. Epub 2015 May 21. Review.

PMID:
26004034
11.

IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment.

Hoeksema MA, Scicluna BP, Boshuizen MC, van der Velden S, Neele AE, Van den Bossche J, Matlung HL, van den Berg TK, Goossens P, de Winther MP.

J Immunol. 2015 Apr 15;194(8):3909-16. doi: 10.4049/jimmunol.1402077. Epub 2015 Mar 6.

12.

Inhibiting epigenetic enzymes to improve atherogenic macrophage functions.

Van den Bossche J, Neele AE, Hoeksema MA, de Heij F, Boshuizen MC, van der Velden S, de Boer VC, Reedquist KA, de Winther MP.

Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):396-402. doi: 10.1016/j.bbrc.2014.11.029. Epub 2014 Nov 18.

PMID:
25446073
13.

PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages.

Szilagyi K, Meijer AB, Neele AE, Verkuijlen P, Leitges M, Dabernat S, Förster-Waldl E, Boztug K, Belot A, Kuijpers TW, Kraal G, de Winther MP, van den Berg TK.

Cardiovasc Res. 2014 Dec 1;104(3):467-76. doi: 10.1093/cvr/cvu213. Epub 2014 Sep 24.

PMID:
25253077
14.

Macrophage polarization: the epigenetic point of view.

Van den Bossche J, Neele AE, Hoeksema MA, de Winther MP.

Curr Opin Lipidol. 2014 Oct;25(5):367-73. doi: 10.1097/MOL.0000000000000109. Review.

PMID:
25188918
15.

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.

Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP.

EMBO Mol Med. 2014 Sep;6(9):1124-32. doi: 10.15252/emmm.201404170.

16.

Transglutaminase activity regulates atherosclerotic plaque composition at locations exposed to oscillatory shear stress.

Matlung HL, Neele AE, Groen HC, van Gaalen K, Tuna BG, van Weert A, de Vos J, Wentzel JJ, Hoogenboezem M, van Buul JD, VanBavel E, Bakker EN.

Atherosclerosis. 2012 Oct;224(2):355-62. doi: 10.1016/j.atherosclerosis.2012.07.044. Epub 2012 Aug 7.

17.

Identification of superior parents in a potato breeding programme.

Neele AE, Nab HJ, Louwes KM.

Theor Appl Genet. 1991 Sep;82(3):264-72. doi: 10.1007/BF02190611.

PMID:
24213169
18.

Optimising visual selection in early clonal generations of potato based on genetic and economic considerations.

Neele AE, Nab HJ, de Jongh de Leeuw MJ, Vroegop AP, Louwes KM.

Theor Appl Genet. 1989 Nov;78(5):665-71. doi: 10.1007/BF00262562.

PMID:
24225827

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