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Items: 43


Combined noninvasive metabolic and spindle imaging as potential tools for embryo and oocyte assessment.

Sanchez T, Venturas M, Aghvami SA, Yang X, Fraden S, Sakkas D, Needleman DJ.

Hum Reprod. 2019 Dec 1;34(12):2349-2361. doi: 10.1093/humrep/dez210.


Electrical control of interlayer exciton dynamics in atomically thin heterostructures.

Jauregui LA, Joe AY, Pistunova K, Wild DS, High AA, Zhou Y, Scuri G, De Greve K, Sushko A, Yu CH, Taniguchi T, Watanabe K, Needleman DJ, Lukin MD, Park H, Kim P.

Science. 2019 Nov 15;366(6467):870-875. doi: 10.1126/science.aaw4194.


From cytoskeletal assemblies to living materials.

Foster PJ, Fürthauer S, Shelley MJ, Needleman DJ.

Curr Opin Cell Biol. 2019 Feb;56:109-114. doi: 10.1016/ Epub 2018 Nov 28. Review.


Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments.

Yoo TY, Choi JM, Conway W, Yu CH, Pappu RV, Needleman DJ.

Elife. 2018 Jul 25;7. pii: e36392. doi: 10.7554/eLife.36392.


The Physics of the Metaphase Spindle.

Oriola D, Needleman DJ, Brugués J.

Annu Rev Biophys. 2018 May 20;47:655-673. doi: 10.1146/annurev-biophys-060414-034107. Review.


Cumulus cell gene expression as a potential biomarker for oocyte quality.

Racowsky C, Needleman DJ.

Fertil Steril. 2018 Mar;109(3):438-439. doi: 10.1016/j.fertnstert.2017.12.013. No abstract available.


Lipopolysaccharide is transported to the cell surface by a membrane-to-membrane protein bridge.

Sherman DJ, Xie R, Taylor RJ, George AH, Okuda S, Foster PJ, Needleman DJ, Kahne D.

Science. 2018 Feb 16;359(6377):798-801. doi: 10.1126/science.aar1886.


Cooperative Accumulation of Dynein-Dynactin at Microtubule Minus-Ends Drives Microtubule Network Reorganization.

Tan R, Foster PJ, Needleman DJ, McKenney RJ.

Dev Cell. 2018 Jan 22;44(2):233-247.e4. doi: 10.1016/j.devcel.2017.12.023.


Chromosomal passenger complex hydrodynamics suggests chaperoning of the inactive state by nucleoplasmin/nucleophosmin.

Hanley ML, Yoo TY, Sonnett M, Needleman DJ, Mitchison TJ.

Mol Biol Cell. 2017 Jun 1;28(11):1444-1456. doi: 10.1091/mbc.E16-12-0860. Epub 2017 Apr 12.


Bridging length scales to measure polymer assembly.

Kaye B, Yoo TY, Foster PJ, Yu CH, Needleman DJ.

Mol Biol Cell. 2017 May 15;28(10):1379-1388. doi: 10.1091/mbc.E16-05-0344. Epub 2017 Mar 29.


Developing and Testing a Bayesian Analysis of Fluorescence Lifetime Measurements.

Kaye B, Foster PJ, Yoo TY, Needleman DJ.

PLoS One. 2017 Jan 6;12(1):e0169337. doi: 10.1371/journal.pone.0169337. eCollection 2017.


Forces positioning the mitotic spindle: Theories, and now experiments.

Wu HY, Nazockdast E, Shelley MJ, Needleman DJ.

Bioessays. 2017 Feb;39(2). doi: 10.1002/bies.201600212. Epub 2016 Dec 27. Review.


Spatial organization of the Ran pathway by microtubules in mitosis.

Oh D, Yu CH, Needleman DJ.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8729-34. doi: 10.1073/pnas.1607498113. Epub 2016 Jul 20.


Mutation Is a Sufficient and Robust Predictor of Genetic Variation for Mitotic Spindle Traits in Caenorhabditis elegans.

Farhadifar R, Ponciano JM, Andersen EC, Needleman DJ, Baer CF.

Genetics. 2016 Aug;203(4):1859-70. doi: 10.1534/genetics.115.185736. Epub 2016 Jun 22.


Studying Kinetochores In Vivo Using FLIM-FRET.

Yoo TY, Needleman DJ.

Methods Mol Biol. 2016;1413:169-86. doi: 10.1007/978-1-4939-3542-0_11.


Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton.

Hu H, Juvekar A, Lyssiotis CA, Lien EC, Albeck JG, Oh D, Varma G, Hung YP, Ullas S, Lauring J, Seth P, Lundquist MR, Tolan DR, Grant AK, Needleman DJ, Asara JM, Cantley LC, Wulf GM.

Cell. 2016 Jan 28;164(3):433-46. doi: 10.1016/j.cell.2015.12.042.


Active contraction of microtubule networks.

Foster PJ, Fürthauer S, Shelley MJ, Needleman DJ.

Elife. 2015 Dec 23;4. pii: e10837. doi: 10.7554/eLife.10837.


Scaling, selection, and evolutionary dynamics of the mitotic spindle.

Farhadifar R, Baer CF, Valfort AC, Andersen EC, Müller-Reichert T, Delattre M, Needleman DJ.

Curr Biol. 2015 Mar 16;25(6):732-740. doi: 10.1016/j.cub.2014.12.060. Epub 2015 Feb 12.


Transformation of taxol-stabilized microtubules into inverted tubulin tubules triggered by a tubulin conformation switch.

Ojeda-Lopez MA, Needleman DJ, Song C, Ginsburg A, Kohl PA, Li Y, Miller HP, Wilson L, Raviv U, Choi MC, Safinya CR.

Nat Mater. 2014 Feb;13(2):195-203. doi: 10.1038/nmat3858. Epub 2014 Jan 19.


Ion specific effects in bundling and depolymerization of taxol-stabilized microtubules.

Needleman DJ, Ojeda-Lopez MA, Raviv U, Miller HP, Li Y, Song C, Feinstein SC, Wilson L, Choi MC, Safinya CR.

Faraday Discuss. 2013;166:31-45.


Nucleation and transport organize microtubules in metaphase spindles.

Brugués J, Nuzzo V, Mazur E, Needleman DJ.

Cell. 2012 Apr 27;149(3):554-64. doi: 10.1016/j.cell.2012.03.027.


Development of time-integrated multipoint moment analysis for spatially resolved fluctuation spectroscopy with high time resolution.

Oh D, Zidovska A, Xu Y, Needleman DJ.

Biophys J. 2011 Sep 21;101(6):1546-54. doi: 10.1016/j.bpj.2011.08.013. Epub 2011 Sep 20.


Nanoscale assembly in biological systems: from neuronal cytoskeletal proteins to curvature stabilizing lipids.

Safinya CR, Raviv U, Needleman DJ, Zidovska A, Choi MC, Ojeda-Lopez MA, Ewert KK, Li Y, Miller HP, Quispe J, Carragher B, Potter CS, Kim MW, Feinstein SC, Wilson L.

Adv Mater. 2011 May 24;23(20):2260-70. doi: 10.1002/adma.201004647. Epub 2011 Apr 20. Review.


Automated identification of microtubules in cellular electron tomography.

Nurgaliev D, Gatanov T, Needleman DJ.

Methods Cell Biol. 2010;97:475-95. doi: 10.1016/S0091-679X(10)97025-8. Review.


Quantitative characterization of filament dynamics by single-molecule lifetime measurements.

Mirny LA, Needleman DJ.

Methods Cell Biol. 2010;95:583-600. doi: 10.1016/S0091-679X(10)95029-2. Review.


Mitosis: taking the measure of spindle length.

Needleman DJ, Farhadifar R.

Curr Biol. 2010 Apr 27;20(8):R359-60. doi: 10.1016/j.cub.2010.02.054.


Fast microtubule dynamics in meiotic spindles measured by single molecule imaging: evidence that the spindle environment does not stabilize microtubules.

Needleman DJ, Groen A, Ohi R, Maresca T, Mirny L, Mitchison T.

Mol Biol Cell. 2010 Jan 15;21(2):323-33. doi: 10.1091/mbc.E09-09-0816. Epub 2009 Nov 25.


Cellular allometry: the spindle in development and inheritance.

Needleman DJ.

Curr Biol. 2009 Sep 29;19(18):R846-7. doi: 10.1016/j.cub.2009.08.028.


Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: a synchrotron x-ray scattering study.

Choi MC, Raviv U, Miller HP, Gaylord MR, Kiris E, Ventimiglia D, Needleman DJ, Kim MW, Wilson L, Feinstein SC, Safinya CR.

Biophys J. 2009 Jul 22;97(2):519-27. doi: 10.1016/j.bpj.2009.04.047.


Pin-hole array correlation imaging: highly parallel fluorescence correlation spectroscopy.

Needleman DJ, Xu Y, Mitchison TJ.

Biophys J. 2009 Jun 17;96(12):5050-9. doi: 10.1016/j.bpj.2009.03.023.


How does a millimeter-sized cell find its center?

Wühr M, Dumont S, Groen AC, Needleman DJ, Mitchison TJ.

Cell Cycle. 2009 Apr 15;8(8):1115-21. Epub 2009 Apr 9. Review.


Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules.

Gatlin JC, Matov A, Groen AC, Needleman DJ, Maresca TJ, Danuser G, Mitchison TJ, Salmon ED.

Curr Biol. 2009 Feb 24;19(4):287-96. doi: 10.1016/j.cub.2009.01.055.


Evidence for an upper limit to mitotic spindle length.

Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ.

Curr Biol. 2008 Aug 26;18(16):1256-61. doi: 10.1016/j.cub.2008.07.092.


Plasmid segregation: is a total understanding within reach?

Needleman DJ.

Curr Biol. 2008 Mar 11;18(5):R212-4. doi: 10.1016/j.cub.2008.01.003.


Microtubule protofilament number is modulated in a stepwise fashion by the charge density of an enveloping layer.

Raviv U, Nguyen T, Ghafouri R, Needleman DJ, Li Y, Miller HP, Wilson L, Bruinsma RF, Safinya CR.

Biophys J. 2007 Jan 1;92(1):278-87. Epub 2006 Oct 6.


Cationic liposome-DNA complexes: from liquid crystal science to gene delivery applications.

Safinya CR, Ewert K, Ahmad A, Evans HM, Raviv U, Needleman DJ, Lin AJ, Slack NL, George C, Samuel CE.

Philos Trans A Math Phys Eng Sci. 2006 Oct 15;364(1847):2573-96.


Cationic membranes complexed with oppositely charged microtubules: hierarchical self-assembly leading to bio-nanotubes.

Raviv U, Needleman DJ, Safinya CR.

J Phys Condens Matter. 2006 Jul 19;18(28):S1271-9. doi: 10.1088/0953-8984/18/28/S10. Epub 2006 Jun 28.


Radial compression of microtubules and the mechanism of action of taxol and associated proteins.

Needleman DJ, Ojeda-Lopez MA, Raviv U, Ewert K, Miller HP, Wilson L, Safinya CR.

Biophys J. 2005 Nov;89(5):3410-23. Epub 2005 Aug 12.


Cationic liposome-microtubule complexes: pathways to the formation of two-state lipid-protein nanotubes with open or closed ends.

Raviv U, Needleman DJ, Li Y, Miller HP, Wilson L, Safinya CR.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11167-72. Epub 2005 Jul 29.


Synchrotron X-ray diffraction study of microtubules buckling and bundling under osmotic stress: a probe of interprotofilament interactions.

Needleman DJ, Ojeda-Lopez MA, Raviv U, Ewert K, Jones JB, Miller HP, Wilson L, Safinya CR.

Phys Rev Lett. 2004 Nov 5;93(19):198104. Epub 2004 Nov 4.


Higher-order assembly of microtubules by counterions: from hexagonal bundles to living necklaces.

Needleman DJ, Ojeda-Lopez MA, Raviv U, Miller HP, Wilson L, Safinya CR.

Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16099-103. Epub 2004 Nov 8.


Helical structure and packing orientation of the S2 segment in the Shaker K+ channel.

Monks SA, Needleman DJ, Miller C.

J Gen Physiol. 1999 Mar;113(3):415-23.

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