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Items: 12

1.

The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation.

Nawaz MH, Ferreira JC, Nedyalkova L, Zhu H, Carrasco-López C, Kirmizialtin S, Rabeh WM.

Biosci Rep. 2018 Feb 21;38(1). pii: BSR20171666. doi: 10.1042/BSR20171666. Print 2018 Feb 28.

2.

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

Hart T, Tong AHY, Chan K, Van Leeuwen J, Seetharaman A, Aregger M, Chandrashekhar M, Hustedt N, Seth S, Noonan A, Habsid A, Sizova O, Nedyalkova L, Climie R, Tworzyanski L, Lawson K, Sartori MA, Alibeh S, Tieu D, Masud S, Mero P, Weiss A, Brown KR, Usaj M, Billmann M, Rahman M, Constanzo M, Myers CL, Andrews BJ, Boone C, Durocher D, Moffat J.

G3 (Bethesda). 2017 Aug 7;7(8):2719-2727. doi: 10.1534/g3.117.041277.

3.

Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents.

Kincaid VA, London N, Wangkanont K, Wesener DA, Marcus SA, Héroux A, Nedyalkova L, Talaat AM, Forest KT, Shoichet BK, Kiessling LL.

ACS Chem Biol. 2015 Oct 16;10(10):2209-18. doi: 10.1021/acschembio.5b00370. Epub 2015 Aug 17.

4.

Colloidal aggregation and the in vitro activity of traditional Chinese medicines.

Duan D, Doak AK, Nedyalkova L, Shoichet BK.

ACS Chem Biol. 2015 Apr 17;10(4):978-88. doi: 10.1021/cb5009487. Epub 2015 Feb 9.

5.

Colloidal drug formulations can explain "bell-shaped" concentration-response curves.

Owen SC, Doak AK, Ganesh AN, Nedyalkova L, McLaughlin CK, Shoichet BK, Shoichet MS.

ACS Chem Biol. 2014 Mar 21;9(3):777-84. doi: 10.1021/cb4007584. Epub 2014 Jan 15.

6.

IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.

Dixon MJ, Gray A, Schenning M, Agacan M, Tempel W, Tong Y, Nedyalkova L, Park HW, Leslie NR, van Aalten DM, Downes CP, Batty IH.

J Biol Chem. 2012 Jun 29;287(27):22483-96. doi: 10.1074/jbc.M112.352773. Epub 2012 Apr 5.

7.

Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E.

Siddiqui N, Tempel W, Nedyalkova L, Volpon L, Wernimont AK, Osborne MJ, Park HW, Borden KL.

J Mol Biol. 2012 Feb 3;415(5):781-92. doi: 10.1016/j.jmb.2011.12.002. Epub 2011 Dec 9.

8.

Structural basis of Rnd1 binding to plexin Rho GTPase binding domains (RBDs).

Wang H, Hota PK, Tong Y, Li B, Shen L, Nedyalkova L, Borthakur S, Kim S, Tempel W, Buck M, Park HW.

J Biol Chem. 2011 Jul 22;286(29):26093-106. doi: 10.1074/jbc.M110.197053. Epub 2011 May 24.

9.

Crystal structure of the N-acetylmannosamine kinase domain of GNE.

Tong Y, Tempel W, Nedyalkova L, Mackenzie F, Park HW.

PLoS One. 2009 Oct 20;4(10):e7165. doi: 10.1371/journal.pone.0007165.

10.

Crystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2.

Tong Y, Park I, Hong BS, Nedyalkova L, Tempel W, Park HW.

Proteins. 2009 Jun;75(4):1040-5. doi: 10.1002/prot.22378. No abstract available.

PMID:
19280598
11.

In situ proteolysis for protein crystallization and structure determination.

Dong A, Xu X, Edwards AM; Midwest Center for Structural Genomics; Structural Genomics Consortium, Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, Ignatchenko A, Joachimiak A, Klostermann N, Kim Y, Korniyenko Y, Minor W, Que Q, Savchenko A, Skarina T, Tan K, Yakunin A, Yee A, Yim V, Zhang R, Zheng H, Akutsu M, Arrowsmith C, Avvakumov GV, Bochkarev A, Dahlgren LG, Dhe-Paganon S, Dimov S, Dombrovski L, Finerty P Jr, Flodin S, Flores A, Gräslund S, Hammerström M, Herman MD, Hong BS, Hui R, Johansson I, Liu Y, Nilsson M, Nedyalkova L, Nordlund P, Nyman T, Min J, Ouyang H, Park HW, Qi C, Rabeh W, Shen L, Shen Y, Sukumard D, Tempel W, Tong Y, Tresagues L, Vedadi M, Walker JR, Weigelt J, Welin M, Wu H, Xiao T, Zeng H, Zhu H.

Nat Methods. 2007 Dec;4(12):1019-21. Epub 2007 Nov 4.

12.

Nicotinamide riboside kinase structures reveal new pathways to NAD+.

Tempel W, Rabeh WM, Bogan KL, Belenky P, Wojcik M, Seidle HF, Nedyalkova L, Yang T, Sauve AA, Park HW, Brenner C.

PLoS Biol. 2007 Oct 2;5(10):e263.

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