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Items: 1 to 50 of 228

1.

Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.

Bonnardel J, T'Jonck W, Gaublomme D, Browaeys R, Scott CL, Martens L, Vanneste B, De Prijck S, Nedospasov SA, Kremer A, Van Hamme E, Borghgraef P, Toussaint W, De Bleser P, Mannaerts I, Beschin A, van Grunsven LA, Lambrecht BN, Taghon T, Lippens S, Elewaut D, Saeys Y, Guilliams M.

Immunity. 2019 Oct 15;51(4):638-654.e9. doi: 10.1016/j.immuni.2019.08.017. Epub 2019 Sep 24.

2.

Properties of Fluorescent Far-Red Anti-TNF Nanobodies.

Gorshkova EN, Efimov GA, Ermakova KD, Vasilenko EA, Yuzhakova DV, Shirmanova MV, Mokhonov VV, Tillib SV, Nedospasov SA, Astrakhantseva IV.

Antibodies (Basel). 2018 Dec 15;7(4). pii: E43. doi: 10.3390/antib7040043.

3.

KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis.

Wen Y, Lu X, Ren J, Privratsky JR, Yang B, Rudemiller NP, Zhang J, Griffiths R, Jain MK, Nedospasov SA, Liu BC, Crowley SD.

J Am Soc Nephrol. 2019 Oct;30(10):1925-1938. doi: 10.1681/ASN.2019020111. Epub 2019 Jul 23.

PMID:
31337692
4.

TNFα is responsible for the canonical offspring number-size trade-off.

Maslennikova SO, Gerlinskaya LA, Kontsevaya GV, Anisimova MV, Nedospasov SA, Feofanova NA, Moshkin MP, Moshkin YM.

Sci Rep. 2019 Mar 14;9(1):4568. doi: 10.1038/s41598-019-38844-9.

5.

Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice.

Piliponsky AM, Shubin NJ, Lahiri AK, Truong P, Clauson M, Niino K, Tsuha AL, Nedospasov SA, Karasuyama H, Reber LL, Tsai M, Mukai K, Galli SJ.

Nat Immunol. 2019 Feb;20(2):129-140. doi: 10.1038/s41590-018-0288-7. Epub 2019 Jan 21.

6.

Mouse models of severe asthma for evaluation of therapeutic cytokine targeting.

Gubernatorova EO, Namakanova OA, Tumanov AV, Drutskaya MS, Nedospasov SA.

Immunol Lett. 2019 Mar;207:73-83. doi: 10.1016/j.imlet.2018.11.012. Epub 2019 Jan 16. Review.

PMID:
30659868
7.

[Proinflammatory and Immunoregulatory Functions of Interleukin 6 as Identified by Reverse Genetics].

Drutskaya MS, Gogoleva VS, Atretkhany KN, Gubernatorova EO, Zvartsev RV, Nosenko MA, Nedospasov SA.

Mol Biol (Mosk). 2018 Nov-Dec;52(6):963-974. doi: 10.1134/S0026898418060058. Review. Russian.

8.

Neonatal Lethality and Inflammatory Phenotype of the New Transgenic Mice with Overexpression of Human Interleukin-6 in Myeloid Cells.

Zvartsev RV, Korshunova DS, Gorshkova EA, Nosenko MA, Korneev KV, Maksimenko OG, Korobko IV, Kuprash DV, Drutskaya MS, Nedospasov SA, Deikin AV.

Dokl Biochem Biophys. 2018 Nov;483(1):344-347. doi: 10.1134/S1607672918060157. Epub 2019 Jan 3.

PMID:
30607736
9.

Novel Biodegradable Polymeric Microparticles Facilitate Scarless Wound Healing by Promoting Re-epithelialization and Inhibiting Fibrosis.

Nosenko MA, Moysenovich AM, Zvartsev RV, Arkhipova AY, Zhdanova AS, Agapov II, Vasilieva TV, Bogush VG, Debabov VG, Nedospasov SA, Moisenovich MM, Drutskaya MS.

Front Immunol. 2018 Dec 4;9:2851. doi: 10.3389/fimmu.2018.02851. eCollection 2018.

10.

Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation.

Gubernatorova EO, Gorshkova EA, Namakanova OA, Zvartsev RV, Hidalgo J, Drutskaya MS, Tumanov AV, Nedospasov SA.

Front Immunol. 2018 Nov 26;9:2718. doi: 10.3389/fimmu.2018.02718. eCollection 2018.

11.

Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity.

Atretkhany KN, Mufazalov IA, Dunst J, Kuchmiy A, Gogoleva VS, Andruszewski D, Drutskaya MS, Faustman DL, Schwabenland M, Prinz M, Kruglov AA, Waisman A, Nedospasov SA.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13051-13056. doi: 10.1073/pnas.1807499115. Epub 2018 Nov 29.

12.

Cytokines as Mediators of Neuroinflammation in Experimental Autoimmune Encephalomyelitis.

Gogoleva VS, Atretkhany KN, Drutskaya MS, Mufazalov IA, Kruglov AA, Nedospasov SA.

Biochemistry (Mosc). 2018 Sep;83(9):1089-1103. doi: 10.1134/S0006297918090110. Review.

13.

Engulfment of mast cell secretory granules on skin inflammation boosts dendritic cell migration and priming efficiency.

Dudeck J, Froebel J, Kotrba J, Lehmann CHK, Dudziak D, Speier S, Nedospasov SA, Schraven B, Dudeck A.

J Allergy Clin Immunol. 2019 May;143(5):1849-1864.e4. doi: 10.1016/j.jaci.2018.08.052. Epub 2018 Oct 17.

PMID:
30339853
14.

Hypoacylated LPS from Foodborne Pathogen Campylobacter jejuni Induces Moderate TLR4-Mediated Inflammatory Response in Murine Macrophages.

Korneev KV, Kondakova AN, Sviriaeva EN, Mitkin NA, Palmigiano A, Kruglov AA, Telegin GB, Drutskaya MS, Sturiale L, Garozzo D, Nedospasov SA, Knirel YA, Kuprash DV.

Front Cell Infect Microbiol. 2018 Feb 27;8:58. doi: 10.3389/fcimb.2018.00058. eCollection 2018.

15.

[Humanization of Murine Monoclonal anti-hTNF Antibody: The F10 Story].

Efimov GA, Raats JMH, Chirivi RGS, van Rosmalen JWG, Nedospasov SA.

Mol Biol (Mosk). 2017 Nov-Dec;51(6):1062-1068. doi: 10.7868/S0026898417060167. Russian.

16.

[Antibody-Based Drugs and Other Recombinant Proteins for Diagnostics and Therapy of Viral Infections, Autoimmune Diseases and Cancer].

Kuprash DV, Garib FY, Nedospasov SA.

Mol Biol (Mosk). 2017 Nov-Dec;51(6):883-885. doi: 10.7868/S0026898417060015. Russian. No abstract available.

17.

Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells.

Schaeuble K, Britschgi MR, Scarpellino L, Favre S, Xu Y, Koroleva E, Lissandrin TKA, Link A, Matloubian M, Ware CF, Nedospasov SA, Tumanov AV, Cyster JG, Luther SA.

Cell Rep. 2017 Nov 28;21(9):2500-2514. doi: 10.1016/j.celrep.2017.10.119.

18.

Induction of ICAM-1 Expression in Mouse Embryonic Fibroblasts Cultured on Fibroin-Gelatin Scaffolds.

Nosenko MA, Maluchenko NV, Drutskaya MS, Arkhipova AY, Agapov II, Nedospasov SA, Moisenovich MM.

Acta Naturae. 2017 Jul-Sep;9(3):89-93.

19.

VHH-Based Bispecific Antibodies Targeting Cytokine Production.

Nosenko MA, Atretkhany KN, Mokhonov VV, Efimov GA, Kruglov AA, Tillib SV, Drutskaya MS, Nedospasov SA.

Front Immunol. 2017 Sep 1;8:1073. doi: 10.3389/fimmu.2017.01073. eCollection 2017.

20.

Tristetraprolin expression by keratinocytes controls local and systemic inflammation.

Andrianne M, Assabban A, La C, Mogilenko D, Salle DS, Fleury S, Doumont G, Van Simaeys G, Nedospasov SA, Blackshear PJ, Dombrowicz D, Goriely S, Van Maele L.

JCI Insight. 2017 Jun 2;2(11). pii: 92979. doi: 10.1172/jci.insight.92979. eCollection 2017 Jun 2.

21.

Can we design a better anti-cytokine therapy?

Drutskaya MS, Efimov GA, Kruglov AA, Nedospasov SA.

J Leukoc Biol. 2017 Sep;102(3):783-790. doi: 10.1189/jlb.3MA0117-025R. Epub 2017 May 25. Review.

PMID:
28546502
22.

Low level of Lck kinase in Th2 cells limits expression of CD4 co-receptor and S73 phosphorylation of transcription factor c-Jun.

Shebzukhov YV, Stanislawiak S, Bezhaeva TR, Nedospasov SA, Kuprash DV.

Sci Rep. 2017 May 24;7(1):2339. doi: 10.1038/s41598-017-02553-y.

23.

Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure.

Kroetsch JT, Levy AS, Zhang H, Aschar-Sobbi R, Lidington D, Offermanns S, Nedospasov SA, Backx PH, Heximer SP, Bolz SS.

Nat Commun. 2017 Apr 5;8:14805. doi: 10.1038/ncomms14805.

24.

Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF.

Wang X, Chen H, Tian R, Zhang Y, Drutskaya MS, Wang C, Ge J, Fan Z, Kong D, Wang X, Cai T, Zhou Y, Wang J, Wang J, Wang S, Qin Z, Jia H, Wu Y, Liu J, Nedospasov SA, Tredget EE, Lin M, Liu J, Jiang Y, Wu Y.

Nat Commun. 2017 Mar 27;8:14091. doi: 10.1038/ncomms14091.

25.

[Evolutionary plasticity of IL-6 cytokine family].

Gorshkova EA, Nedospasov SA, Shilov ES.

Mol Biol (Mosk). 2016 Nov-Dec;50(6):1039-1048. doi: 10.7868/S0026898416060069. Russian.

26.

Modeling of viral-bacterial coinfections at the molecular level using agonists of innate immunity receptors.

Sviriaeva EN, Korneev KV, Drutskaya MS, Nedospasov SA, Kuprash DV.

Dokl Biochem Biophys. 2016 Nov;471(1):393-395. doi: 10.1134/S1607672916060053. Epub 2017 Jan 6.

PMID:
28058677
27.

[Cytokine neutralization at specific cellular source : A new therapeutic paradigm? German Version].

Kruglov AA, Nedospasov SA.

Z Rheumatol. 2017 Mar;76(2):163-165. doi: 10.1007/s00393-016-0244-6. German.

PMID:
28058501
28.

Microbiota Induces Expression of Tumor Necrosis Factor in Postnatal Mouse Skin.

Yuzhakova DV, Shirmanova MV, Bocharov AA, Astrakhantseva IV, Vasilenko EA, Gorshkova EN, Drutskaya MS, Zagaynova EV, Nedospasov SA, Kruglov AA.

Biochemistry (Mosc). 2016 Nov;81(11):1303-1308.

29.

Effects of Fibroin Microcarriers on Inflammation and Regeneration of Deep Skin Wounds in Mice.

Arkhipova AY, Nosenko MA, Malyuchenko NV, Zvartsev RV, Moisenovich AM, Zhdanova AS, Vasil'eva TV, Gorshkova EA, Agapov II, Drutskaya MS, Nedospasov SA, Moisenovich MM.

Biochemistry (Mosc). 2016 Nov;81(11):1251-1260.

30.

Molecular and Cellular Mechanisms of Inflammation.

Kuprash DV, Nedospasov SA.

Biochemistry (Mosc). 2016 Nov;81(11):1237-1239.

31.

Cytokine neutralization at specific cellular source : A new therapeutic paradigm?

Kruglov AA, Nedospasov SA.

Z Rheumatol. 2017 Mar;76(Suppl 1):22-24. doi: 10.1007/s00393-016-0215-y.

PMID:
27787607
32.

Short Communication: Accumulation of Neutral Lipids in Liver and Aorta of Nef-Transgenic Mice.

Pushkarsky T, Shilov E, Kruglova N, Naumann R, Brichacek B, Jennelle L, Sviridov D, Kruglov A, Nedospasov SA, Bukrinsky M.

AIDS Res Hum Retroviruses. 2017 Jan;33(1):57-60. doi: 10.1089/AID.2016.0128. Epub 2016 Oct 25.

33.

Making anti-cytokine therapy more selective: Studies in mice.

Drutskaya MS, Efimov GA, Astrakhantseva IV, Kruglov AA, Nedospasov SA.

Cytokine. 2018 Jan;101:33-38. doi: 10.1016/j.cyto.2016.08.022. Epub 2016 Sep 10. Review.

PMID:
27624866
34.

Chemokines, cytokines and exosomes help tumors to shape inflammatory microenvironment.

Atretkhany KN, Drutskaya MS, Nedospasov SA, Grivennikov SI, Kuprash DV.

Pharmacol Ther. 2016 Dec;168:98-112. doi: 10.1016/j.pharmthera.2016.09.011. Epub 2016 Sep 6. Review.

PMID:
27613100
35.

Bioengineering of Artificial Lymphoid Organs.

Nosenko MA, Drutskaya MS, Moisenovich MM, Nedospasov SA.

Acta Naturae. 2016 Apr-Jun;8(2):10-23.

36.

Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling.

Clausen BH, Degn M, Sivasaravanaparan M, Fogtmann T, Andersen MG, Trojanowsky MD, Gao H, Hvidsten S, Baun C, Deierborg T, Finsen B, Kristensen BW, Bak ST, Meyer M, Lee J, Nedospasov SA, Brambilla R, Lambertsen KL.

Sci Rep. 2016 Jul 7;6:29291. doi: 10.1038/srep29291.

37.

Tumor Necrosis Factor/Sphingosine-1-Phosphate Signaling Augments Resistance Artery Myogenic Tone in Diabetes.

Sauvé M, Hui SK, Dinh DD, Foltz WD, Momen A, Nedospasov SA, Offermanns S, Husain M, Kroetsch JT, Lidington D, Bolz SS.

Diabetes. 2016 Jul;65(7):1916-28. doi: 10.2337/db15-1450. Epub 2016 Apr 5.

38.

TNF Neutralization Results in the Delay of Transplantable Tumor Growth and Reduced MDSC Accumulation.

Atretkhany KS, Nosenko MA, Gogoleva VS, Zvartsev RV, Qin Z, Nedospasov SA, Drutskaya MS.

Front Immunol. 2016 Apr 19;7:147. doi: 10.3389/fimmu.2016.00147. eCollection 2016.

39.

Cell-type-restricted anti-cytokine therapy: TNF inhibition from one pathogenic source.

Efimov GA, Kruglov AA, Khlopchatnikova ZV, Rozov FN, Mokhonov VV, Rose-John S, Scheller J, Gordon S, Stacey M, Drutskaya MS, Tillib SV, Nedospasov SA.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3006-11. doi: 10.1073/pnas.1520175113. Epub 2016 Mar 2.

40.

TLR-signaling and proinflammatory cytokines as drivers of tumorigenesis.

Korneev KV, Atretkhany KN, Drutskaya MS, Grivennikov SI, Kuprash DV, Nedospasov SA.

Cytokine. 2017 Jan;89:127-135. doi: 10.1016/j.cyto.2016.01.021. Epub 2016 Feb 4. Review.

PMID:
26854213
41.

Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI.

Zhang J, Rudemiller NP, Patel MB, Wei Q, Karlovich NS, Jeffs AD, Wu M, Sparks MA, Privratsky JR, Herrera M, Gurley SB, Nedospasov SA, Crowley SD.

J Am Soc Nephrol. 2016 Aug;27(8):2257-64. doi: 10.1681/ASN.2015060683. Epub 2016 Jan 7.

42.

[Interleukin-6 From molecular mechanisms of signal transduction to physiological properties and therapeutic targeting].

Drutskaya MS, Nosenko MA, Atretkhany KS, Efimov GA, Nedospasov SA.

Mol Biol (Mosk). 2015 Nov-Dec;49(6):937-43. doi: 10.7868/S0026898415060063. Review. Russian.

43.

Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei, Acinetobacter baumannii, and Pseudomonas aeruginosa.

Korneev KV, Arbatsky NP, Molinaro A, Palmigiano A, Shaikhutdinova RZ, Shneider MM, Pier GB, Kondakova AN, Sviriaeva EN, Sturiale L, Garozzo D, Kruglov AA, Nedospasov SA, Drutskaya MS, Knirel YA, Kuprash DV.

Front Immunol. 2015 Nov 23;6:595. doi: 10.3389/fimmu.2015.00595. eCollection 2015.

44.

Mast-Cell-Derived TNF Amplifies CD8(+) Dendritic Cell Functionality and CD8(+) T Cell Priming.

Dudeck J, Ghouse SM, Lehmann CH, Hoppe A, Schubert N, Nedospasov SA, Dudziak D, Dudeck A.

Cell Rep. 2015 Oct 13;13(2):399-411. doi: 10.1016/j.celrep.2015.08.078. Epub 2015 Sep 24.

45.

Serum Immunoproteomics Combined With Pathological Reassessment of Surgical Specimens Identifies TCP-1ζ Autoantibody as a Potential Biomarker in Thyroid Neoplasia.

Belousov PV, Bogolyubova AV, Kim YS, Abrosimov AY, Kopylov AT, Tvardovskiy AA, Lanshchakov KV, Sazykin AY, Dvinskikh NY, Bobrovskaya YI, Selivanova LS, Shilov ES, Schwartz AM, Shebzukhov YV, Severskaia NV, Vanushko VE, Moshkovskii SA, Nedospasov SA, Kuprash DV.

J Clin Endocrinol Metab. 2015 Sep;100(9):E1206-15. doi: 10.1210/jc.2014-4260. Epub 2015 Jul 21.

PMID:
26196948
46.

Inflammation-induced formation of fat-associated lymphoid clusters.

Bénézech C, Luu NT, Walker JA, Kruglov AA, Loo Y, Nakamura K, Zhang Y, Nayar S, Jones LH, Flores-Langarica A, McIntosh A, Marshall J, Barone F, Besra G, Miles K, Allen JE, Gray M, Kollias G, Cunningham AF, Withers DR, Toellner KM, Jones ND, Veldhoen M, Nedospasov SA, McKenzie ANJ, Caamaño JH.

Nat Immunol. 2015 Aug;16(8):819-828. doi: 10.1038/ni.3215. Epub 2015 Jun 29.

47.

Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage.

Yagi K, Lidington D, Wan H, Fares JC, Meissner A, Sumiyoshi M, Ai J, Foltz WD, Nedospasov SA, Offermanns S, Nagahiro S, Macdonald RL, Bolz SS.

Stroke. 2015 Aug;46(8):2260-70. doi: 10.1161/STROKEAHA.114.006365. Epub 2015 Jul 2.

PMID:
26138121
48.

Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF.

Olleros ML, Chavez-Galan L, Segueni N, Bourigault ML, Vesin D, Kruglov AA, Drutskaya MS, Bisig R, Ehlers S, Aly S, Walter K, Kuprash DV, Chouchkova M, Kozlov SV, Erard F, Ryffel B, Quesniaux VF, Nedospasov SA, Garcia I.

Infect Immun. 2015 Sep;83(9):3612-23. doi: 10.1128/IAI.00743-15. Epub 2015 Jun 29.

49.

Macrophage-derived tumor necrosis factor-α mediates diabetic renal injury.

Awad AS, You H, Gao T, Cooper TK, Nedospasov SA, Vacher J, Wilkinson PF, Farrell FX, Brian Reeves W.

Kidney Int. 2015 Oct;88(4):722-33. doi: 10.1038/ki.2015.162. Epub 2015 Jun 10.

50.

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors.

Lemos DR, Babaeijandaghi F, Low M, Chang CK, Lee ST, Fiore D, Zhang RH, Natarajan A, Nedospasov SA, Rossi FM.

Nat Med. 2015 Jul;21(7):786-94. doi: 10.1038/nm.3869. Epub 2015 Jun 8.

PMID:
26053624

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