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Items: 42


Different development of myelin basic protein agonist- and antagonist-specific human TCR transgenic T cells in the thymus and periphery.

Kawamura K, Yao K, Shukaliak-Quandt JA, Huh J, Baig M, Quigley L, Ito N, Necker A, McFarland HF, Muraro PA, Martin R, Ito K.

J Immunol. 2008 Oct 15;181(8):5462-72.


Use of a lentiviral vector encoding a HCMV-chimeric IE1-pp65 protein for epitope identification in HLA-Transgenic mice and for ex vivo stimulation and expansion of CD8(+) cytotoxic T cells from human peripheral blood cells.

Rohrlich PS, Cardinaud S, Lulè J, Montero-Julian FA, Prodhomme V, Firat H, Davignon JL, Perret E, Monseaux S, Necker A, Michelson S, Lemonnier FA, Charneau P, Davrinche C.

Hum Immunol. 2004 May;65(5):514-22.


Genomic absence of the gene encoding T cell receptor Vbeta7.2 is linked to the presence of autoantibodies in Sjögren's syndrome.

Manavalan SJ, Valiando JR, Reeves WH, Arnett FC, Necker A, Simantov R, Lyons R, Satoh M, Posnett DN.

Arthritis Rheum. 2004 Jan;50(1):187-98.


Characterization of antigen-specific repertoire diversity following in vitro restimulation by a recombinant adenovirus expressing human cytomegalovirus pp65.

Hamel Y, Rohrlich P, Baron V, Bonhomme D, Rieux-Laucat F, Necker A, Lemonnier F, Ferradini L, Fischer A, Cavazzana-Calvo M.

Eur J Immunol. 2003 Mar;33(3):760-8.


Cytotoxic T-lymphocyte responses in melanoma through in vitro stimulation with the Melan-A peptide analogue A27L: a qualitative analysis.

Palermo B, Campanelli R, Garbelli S, Mantovani S, Robustelli Della Cuna G, Necker A, Manganoni AM, Carella G, Rivoltini L, Lantelme E, Giachino C.

Melanoma Res. 2002 Oct;12(5):491-8.


Longitudinal analysis of the T-cell receptor (TCR)-VA and -VB repertoire in CD8+ T cells from individuals immunized with recombinant hepatitis B surface antigen.

Höhn H, Neukirch C, Freitag K, Necker A, Hitzler W, Seliger B, Maeurer MJ.

Clin Exp Immunol. 2002 Aug;129(2):309-17.


Peptide-specific CD8+ T-cell evolution in vivo: response to peptide vaccination with Melan-A/MART-1.

Jäger E, Höhn H, Necker A, Förster R, Karbach J, Freitag K, Neukirch C, Castelli C, Salter RD, Knuth A, Maeurer MJ.

Int J Cancer. 2002 Mar 20;98(3):376-88.


Impact of antigen presentation on TCR modulation and cytokine release: implications for detection and sorting of antigen-specific CD8+ T cells using HLA-A2 wild-type or HLA-A2 mutant tetrameric complexes.

Jäger E, Salter R, Castelli C, Höhn H, Freitag K, Karbach J, Neukirch C, Necker A, Knuth A, Maeurer MJ.

J Immunol. 2002 Mar 15;168(6):2766-72.


Improved assessment of T-cell receptor (TCR) VB repertoire in clinical specimens: combination of TCR-CDR3 spectratyping with flow cytometry-based TCR VB frequency analysis.

Pilch H, Höhn H, Freitag K, Neukirch C, Necker A, Haddad P, Tanner B, Knapstein PG, Maeurer MJ.

Clin Diagn Lab Immunol. 2002 Mar;9(2):257-66.


Improved detection of melanoma antigen-specific T cells expressing low or high levels of CD8 by HLA-A2 tetramers presenting a Melan-A/Mart-1 peptide analogue.

Maeurer MJ, Necker A, Salter RD, Castelli C, Höhn H, Karbach J, Freitag K, Neukirch C, Knuth A, Jäger E.

Int J Cancer. 2002 Jan 1;97(1):64-71.


Human CD8 co-receptor is strictly involved in MHC-peptide tetramer-TCR binding and T cell activation.

Campanelli R, Palermo B, Garbelli S, Mantovani S, Lucchi P, Necker A, Lantelme E, Giachino C.

Int Immunol. 2002 Jan;14(1):39-44.


Antigen recognition by T cells: a strong sense of structure.

Maeurer M, Höhn H, Castelli C, Salter RD, Necker A, Reichert T, Knuth A, Jäger E.

Trends Immunol. 2001 Nov;22(11):599-601. No abstract available.


Clonally diverse CTL response to a dominant viral epitope recognizes potential epitope variants.

Charini WA, Kuroda MJ, Schmitz JE, Beaudry KR, Lin W, Lifton MA, Krivulka GR, Necker A, Letvin NL.

J Immunol. 2001 Nov 1;167(9):4996-5003.


Specific cytotoxic T lymphocyte responses against Melan-A/MART1, tyrosinase and gp100 in vitiligo by the use of major histocompatibility complex/peptide tetramers: the role of cellular immunity in the etiopathogenesis of vitiligo.

Palermo B, Campanelli R, Garbelli S, Mantovani S, Lantelme E, Brazzelli V, Ardigó M, Borroni G, Martinetti M, Badulli C, Necker A, Giachino C.

J Invest Dermatol. 2001 Aug;117(2):326-32.


Diverse expansion potential and heterogeneous avidity in tumor-associated antigen-specific T lymphocytes from primary melanoma patients.

Palermo B, Campanelli R, Mantovani S, Lantelme E, Manganoni AM, Carella G, Da Prada G, della Cuna GR, Romagne F, Gauthier L, Necker A, Giachino C.

Eur J Immunol. 2001 Feb;31(2):412-20.


Relationships between natural T cells, atopy, IgE levels, and IL-4 production.

Magnan A, Mély L, Prato S, Vervloet D, Romagné F, Camilla C, Necker A, Casano B, Montero-Jullian F, Fert V, Malissen B, Bongrand P.

Allergy. 2000 Mar;55(3):286-90.


Rapid identification of local T cell expansion in inflammatory organ diseases by flow cytometric T cell receptor Vbeta analysis.

Muraro PA, Jacobsen M, Necker A, Nagle JW, Gaber R, Sommer N, Oertel WH, Martin R, Hemmer B.

J Immunol Methods. 2000 Dec 1;246(1-2):131-43.


Identification of major epitopes of Mycobacterium tuberculosis AG85B that are recognized by HLA-A*0201-restricted CD8+ T cells in HLA-transgenic mice and humans.

Geluk A, van Meijgaarden KE, Franken KL, Drijfhout JW, D'Souza S, Necker A, Huygen K, Ottenhoff TH.

J Immunol. 2000 Dec 1;165(11):6463-71.


Human papillomavirus type 33 E7 peptides presented by HLA-DR*0402 to tumor-infiltrating T cells in cervical cancer.

Höhn H, Pilch H, Günzel S, Neukirch C, Freitag K, Necker A, Maeurer MJ.

J Virol. 2000 Jul;74(14):6632-6.


Clonal expansion of Melan A-specific cytotoxic T lymphocytes in a melanoma patient responding to continued immunization with melanoma-associated peptides.

Jäger E, Maeurer M, Höhn H, Karbach J, Jäger D, Zidianakis Z, Bakhshandeh-Bath A, Orth J, Neukirch C, Necker A, Reichert TE, Knuth A.

Int J Cancer. 2000 May 15;86(4):538-47.


Immunophenotypic and immunogenotypic characteristics of TCRgammadelta+ T cell acute lymphoblastic leukemia.

Langerak AW, Wolvers-Tettero IL, van den Beemd MW, van Wering ER, Ludwig WD, Hählen K, Necker A, van Dongen JJ.

Leukemia. 1999 Feb;13(2):206-14.


Close phenotypic and functional similarities between human and murine alphabeta T cells expressing invariant TCR alpha-chains.

Davodeau F, Peyrat MA, Necker A, Dominici R, Blanchard F, Leget C, Gaschet J, Costa P, Jacques Y, Godard A, Vie H, Poggi A, Romagné F, Bonneville M.

J Immunol. 1997 Jun 15;158(12):5603-11.


TCRBV23 specificity of two monoclonal antibodies revealed by a panel of human V beta chains expressed in mouse cells.

Romagné F, Kanagawa O, David-Ameline J, Peyrat MA, Bonneville M, Necker A.

J Immunol Methods. 1995 Oct 26;186(2):313-22.


Alterations of T cell repertoire after bone marrow transplantation: characterization of over-represented subsets.

Gaschet J, Denis C, Milpied N, Hallet MM, Romagné F, Necker A, Vivien R, David-Ameline J, Davodeau F, Bonneville M, et al.

Bone Marrow Transplant. 1995 Sep;16(3):427-35.


Analysis of T-cell receptor V beta expression among V alpha subsets. Evidence for tight regulation of the combinatorial diversity.

Gaschet J, Denis C, Milpied N, Hallet MM, Davodeau F, Necker A, Romagné F, Bonneville M, Vié H.

Ann N Y Acad Sci. 1995 Jul 7;756:84-6. No abstract available.


Generation of a panel of transfected murine cells expressing human V beta. Application to the study of fine specificities of superantigens.

Romagné F, Necker A, Rocher C, Malissen B, Fleischer B.

Ann N Y Acad Sci. 1995 Jul 7;756:120-3. No abstract available.


Monoclonal antibodies to human T-cell receptor variable beta regions.

Necker A, Michalaki H, Raynal MC, Rocher C, Diu A, Romagné F.

Ann N Y Acad Sci. 1995 Jul 7;756:106-9. No abstract available.


Dual T cell receptor beta chain expression on human T lymphocytes.

Davodeau F, Peyrat MA, Romagné F, Necker A, Hallet MM, Vié H, Bonneville M.

J Exp Med. 1995 Apr 1;181(4):1391-8.


Secretion of disulfide-linked human T-cell receptor gamma delta heterodimers.

Davodeau F, Houde I, Boulot G, Romagné F, Necker A, Canavo N, Peyrat MA, Hallet MM, Vié H, Jacques Y, et al.

J Biol Chem. 1993 Jul 25;268(21):15455-60.


H-2-restricted cytolytic T lymphocytes specific for HLA display T cell receptors of limited diversity.

Casanova JL, Cerottini JC, Matthes M, Necker A, Gournier H, Barra C, Widmann C, MacDonald HR, Lemonnier F, Malissen B, Maryanski JL.

J Exp Med. 1992 Aug 1;176(2):439-47.


Monoclonal antibodies raised against engineered soluble mouse T cell receptors and specific for V alpha 8-, V beta 2- or V beta 10-bearing T cells.

Necker A, Rebaï N, Matthes M, Jouvin-Marche E, Cazenave PA, Swarnworawong P, Palmer E, MacDonald HR, Malissen B.

Eur J Immunol. 1991 Dec;21(12):3035-40.


Engineered secreted T-cell receptor alpha beta heterodimers.

Grégoire C, Rebaï N, Schweisguth F, Necker A, Mazza G, Auphan N, Millward A, Schmitt-Verhulst AM, Malissen B.

Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):8077-81.


Human cytomegalovirus structural components: intracellular and intraviral localization of p38.

Landini MP, Severi B, Cenacchi G, Lazzarotto T, Lindenmeier W, Necker A.

Virus Res. 1991 May;19(2-3):189-98.


Large-scale screening of human sera with cytomegalovirus recombinant antigens.

Landini MP, Guan MX, Jahn G, Lindenmaier W, Mach M, Ripalti A, Necker A, Lazzarotto T, Plachter B.

J Clin Microbiol. 1990 Jun;28(6):1375-9.


Detection of Blastocystis hominis by direct microscopy and culture.

Kukoschke KG, Necker A, Müller HE.

Eur J Clin Microbiol Infect Dis. 1990 Apr;9(4):305-7. No abstract available.


Cloning and characterization of major antigenic determinants of human cytomegalovirus Ad169 seen by the human immune system.

Lindenmaier W, Necker A, Krause S, Bonewald R, Collins J.

Arch Virol. 1990;113(1-2):1-16.


Isolation of a functional human interleukin 2 gene from a cosmid library by recombination in vivo.

Lindenmaier W, Dittmar KE, Hauser H, Necker A, Sebald W.

Gene. 1985;39(1):33-9.


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