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Items: 14


The ellagitannin metabolite urolithin C is a glucose-dependent regulator of insulin secretion through activation of L-type calcium channels.

Bayle M, Neasta J, Dall'Asta M, Gautheron G, Virsolvy A, Quignard JF, Youl E, Magous R, Guichou JF, Crozier A, Del Rio D, Cros G, Oiry C.

Br J Pharmacol. 2019 Aug 4. doi: 10.1111/bph.14821. [Epub ahead of print]


N-Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor.

M'Kadmi C, Cabral A, Barrile F, Giribaldi J, Cantel S, Damian M, Mary S, Denoyelle S, Dutertre S, Péraldi-Roux S, Neasta J, Oiry C, Banères JL, Marie J, Perello M, Fehrentz JA.

J Med Chem. 2019 Jan 24;62(2):965-973. doi: 10.1021/acs.jmedchem.8b01644. Epub 2018 Dec 24.


Activation of the cAMP Pathway Induces RACK1-Dependent Binding of β-Actin to BDNF Promoter.

Neasta J, Fiorenza A, He DY, Phamluong K, Kiely PA, Ron D.

PLoS One. 2016 Aug 9;11(8):e0160948. doi: 10.1371/journal.pone.0160948. eCollection 2016.


The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces dopamine release.

Neasta J, Valmalle C, Coyne AC, Carnazzi E, Subra G, Galleyrand JC, Gagne D, M'Kadmi C, Bernad N, Bergé G, Cantel S, Marin P, Marie J, Banères JL, Kemel ML, Daugé V, Puget K, Martinez J.

Br J Pharmacol. 2016 Apr;173(8):1314-28. doi: 10.1111/bph.13424. Epub 2016 Mar 8.


mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse.

Neasta J, Barak S, Hamida SB, Ron D.

J Neurochem. 2014 Jul;130(2):172-84. doi: 10.1111/jnc.12725. Epub 2014 Apr 19. Review.


Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse.

Barak S, Liu F, Ben Hamida S, Yowell QV, Neasta J, Kharazia V, Janak PH, Ron D.

Nat Neurosci. 2013 Aug;16(8):1111-7. doi: 10.1038/nn.3439. Epub 2013 Jun 23.


The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors.

Ben Hamida S, Neasta J, Lasek AW, Kharazia V, Zou M, Carnicella S, Janak PH, Ron D.

J Neurosci. 2012 Nov 7;32(45):15849-58. doi: 10.1523/JNEUROSCI.2846-12.2012.


Direct interaction between scaffolding proteins RACK1 and 14-3-3ζ regulates brain-derived neurotrophic factor (BDNF) transcription.

Neasta J, Kiely PA, He DY, Adams DR, O'Connor R, Ron D.

J Biol Chem. 2012 Jan 2;287(1):322-36. doi: 10.1074/jbc.M111.272195. Epub 2011 Nov 8.


AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors.

Neasta J, Ben Hamida S, Yowell QV, Carnicella S, Ron D.

Biol Psychiatry. 2011 Sep 15;70(6):575-82. doi: 10.1016/j.biopsych.2011.03.019. Epub 2011 May 6.


Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders.

Neasta J, Ben Hamida S, Yowell Q, Carnicella S, Ron D.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20093-8. doi: 10.1073/pnas.1005554107. Epub 2010 Nov 1.


Epigenetic regulation of BDNF expression via the scaffolding protein RACK1.

He DY, Neasta J, Ron D.

J Biol Chem. 2010 Jun 18;285(25):19043-50. doi: 10.1074/jbc.M110.100693. Epub 2010 Apr 21.


Neuropeptide FF-sensitive confinement of mu opioid receptor does not involve lipid rafts in SH-SY5Y cells.

Moulédous L, Merker S, Neasta J, Roux B, Zajac JM, Mollereau C.

Biochem Biophys Res Commun. 2008 Aug 15;373(1):80-4. doi: 10.1016/j.bbrc.2008.05.174. Epub 2008 Jun 9.


Effect of long-term exposure of SH-SY5Y cells to morphine: a whole cell proteomic analysis.

Neasta J, Uttenweiler-Joseph S, Chaoui K, Monsarrat B, Meunier JC, Moulédous L.

Proteome Sci. 2006 Dec 21;4:23.


Long-term morphine treatment enhances proteasome-dependent degradation of G beta in human neuroblastoma SH-SY5Y cells: correlation with onset of adenylate cyclase sensitization.

Moulédous L, Neasta J, Uttenweiler-Joseph S, Stella A, Matondo M, Corbani M, Monsarrat B, Meunier JC.

Mol Pharmacol. 2005 Aug;68(2):467-76. Epub 2005 May 18.


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