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Items: 1 to 50 of 78

1.

Cardiac electrical instability in newly diagnosed/chronic epilepsy tracked by Holter and ECG patch.

Pang TD, Nearing BD, Krishnamurthy KB, Olin B, Schachter SC, Verrier RL.

Neurology. 2019 Sep 3;93(10):450-458. doi: 10.1212/WNL.0000000000008077.

PMID:
31477610
2.

Exercise and pharmacologic stress-induced interlead T-wave heterogeneity analysis to detect clinically significant coronary artery stenosis.

Silva AC, de Antonio VZ, Sroubek J, Gervino E, Ho K, Medeiros SA, Silva FT, Pedreira GC, Stocco FG, Nearing BD, Verrier RL.

Int J Cardiol. 2019 Aug 7. pii: S0167-5273(19)33137-7. doi: 10.1016/j.ijcard.2019.07.066. [Epub ahead of print]

PMID:
31412992
3.

Repolarization Heterogeneity Measured With T-Wave Area Dispersion in Standard 12-Lead ECG Predicts Sudden Cardiac Death in General Population.

Kenttä TV, Sinner MF, Nearing BD, Freudling R, Porthan K, Tikkanen JT, Müller-Nurasyid M, Schramm K, Viitasalo M, Jula A, Nieminen MS, Peters A, Salomaa V, Oikarinen L, Verrier RL, Kääb S, Junttila MJ, Huikuri HV.

Circ Arrhythm Electrophysiol. 2018 Feb;11(2):e005762. doi: 10.1161/CIRCEP.117.005762.

PMID:
29440187
4.

Marked exercise-induced T-wave heterogeneity in symptomatic diabetic patients with nonflow-limiting coronary artery stenosis.

Stocco FG, Evaristo E, Shah NR, Cheezum MK, Hainer J, Foster C, Nearing BD, Gervino E, Verrier RL.

Ann Noninvasive Electrocardiol. 2018 Mar;23(2):e12503. doi: 10.1111/anec.12503. Epub 2017 Sep 26.

5.

Interlead heterogeneity of R- and T-wave morphology in standard 12-lead ECGs predicts sustained ventricular tachycardia/fibrillation and arrhythmic death in patients with cardiomyopathy.

Tan AY, Nearing BD, Rosenberg M, Nezafat R, Josephson ME, Verrier RL.

J Cardiovasc Electrophysiol. 2017 Nov;28(11):1324-1333. doi: 10.1111/jce.13288. Epub 2017 Aug 4.

PMID:
28675579
6.

Ranolazine reduces repolarization heterogeneity in symptomatic patients with diabetes and non-flow-limiting coronary artery stenosis.

Evaristo E, Stocco FG, Shah NR, Cheezum MK, Hainer J, Foster C, Nearing BD, Di Carli M, Verrier RL.

Ann Noninvasive Electrocardiol. 2018 Jan;23(1). doi: 10.1111/anec.12480. Epub 2017 Jun 27.

7.

Quantitative evaluation of heartbeat interval time series using Poincaré analysis reveals distinct patterns of heart rate dynamics during cycles of vagus nerve stimulation in patients with heart failure.

Libbus I, Nearing BD, Amurthur B, KenKnight BH, Verrier RL.

J Electrocardiol. 2017 Nov - Dec;50(6):898-903. doi: 10.1016/j.jelectrocard.2017.06.007. Epub 2017 Jun 8.

8.

The Selective Late Sodium Current Inhibitor Eleclazine, Unlike Amiodarone, Does Not Alter Defibrillation Threshold or Dominant Frequency of Ventricular Fibrillation.

Silva AF, Bonatti R, Batatinha JA, Nearing BD, Zeng D, Belardinelli L, Verrier RL.

J Cardiovasc Pharmacol. 2017 Mar;69(3):178-182. doi: 10.1097/FJC.0000000000000455.

PMID:
28045761
9.

T-Wave Alternans, Heart Rate Turbulence, and Ventricular Ectopy in Standard versus Daily Hemodialysis: Results from the FHN Daily Trial.

Kaplan RM, Herzog CA, Larive B, Subacius H, Nearing BD, Verrier R, Passman RS.

Ann Noninvasive Electrocardiol. 2016 Nov;21(6):566-571. doi: 10.1111/anec.12354. Epub 2016 Mar 28.

PMID:
27778458
10.

Eleclazine, an inhibitor of the cardiac late sodium current, is superior to flecainide in suppressing catecholamine-induced ventricular tachycardia and T-wave alternans in an intact porcine model.

Bacic D, Carneiro JS, Bento AA, Nearing BD, Rajamani S, Belardinelli L, Verrier RL.

Heart Rhythm. 2017 Mar;14(3):448-454. doi: 10.1016/j.hrthm.2016.10.021. Epub 2016 Oct 21.

PMID:
27777148
11.
12.
13.

Acute Autonomic Engagement Assessed by Heart Rate Dynamics During Vagus Nerve Stimulation in Patients With Heart Failure in the ANTHEM-HF Trial.

Nearing BD, Libbus I, Amurthur B, Kenknight BH, Verrier RL.

J Cardiovasc Electrophysiol. 2016 Sep;27(9):1072-7. doi: 10.1111/jce.13017. Epub 2016 Jul 7.

PMID:
27221316
14.

Eleclazine, a new selective cardiac late sodium current inhibitor, confers concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in an intact porcine model.

Fuller H, Justo F, Nearing BD, Kahlig KM, Rajamani S, Belardinelli L, Verrier RL.

Heart Rhythm. 2016 Aug;13(8):1679-86. doi: 10.1016/j.hrthm.2016.04.015. Epub 2016 Apr 21.

PMID:
27108587
15.

Screening for Cardiac Magnetic Resonance Scar Features by 12-Lead ECG, in Patients with Preserved Ejection Fraction.

Mewton N, Strauss DG, Rizzi P, Verrier RL, Liu CY, Tereshchenko LG, Nearing B, Volpe GJ, Marchlinski FE, Moxley J, Killian T, Wu KC, Spooner P, Lima JA.

Ann Noninvasive Electrocardiol. 2016 Jan;21(1):49-59. doi: 10.1111/anec.12264.

16.

Letter to the Editor--Can reducing quantitative T-wave alternans save lives?

Libbus I, Nearing BD, Amurthur B, KenKnight BH, Verrier RL.

Heart Rhythm. 2016 Apr;13(4):e89. doi: 10.1016/j.hrthm.2015.12.044. Epub 2015 Dec 29. No abstract available.

PMID:
26744097
17.

Prediction of sudden cardiac death with automated high-throughput analysis of heterogeneity in standard resting 12-lead electrocardiograms.

Kenttä TV, Nearing BD, Porthan K, Tikkanen JT, Viitasalo M, Nieminen MS, Salomaa V, Oikarinen L, Jula A, Kontula K, Newton-Cheh C, Huikuri HV, Verrier RL.

Heart Rhythm. 2016 Mar;13(3):713-20. doi: 10.1016/j.hrthm.2015.11.035. Epub 2015 Nov 23.

PMID:
26616400
18.

Autonomic regulation therapy suppresses quantitative T-wave alternans and improves baroreflex sensitivity in patients with heart failure enrolled in the ANTHEM-HF study.

Libbus I, Nearing BD, Amurthur B, KenKnight BH, Verrier RL.

Heart Rhythm. 2016 Mar;13(3):721-8. doi: 10.1016/j.hrthm.2015.11.030. Epub 2015 Nov 18.

19.

Unmasking atrial repolarization to assess alternans, spatiotemporal heterogeneity, and susceptibility to atrial fibrillation.

Verrier RL, Fuller H, Justo F, Nearing BD, Rajamani S, Belardinelli L.

Heart Rhythm. 2016 Apr;13(4):953-61. doi: 10.1016/j.hrthm.2015.11.019. Epub 2015 Nov 23.

PMID:
26592850
20.

The Selective Cardiac Late Sodium Current Inhibitor GS-458967 Suppresses Autonomically Triggered Atrial Fibrillation in an Intact Porcine Model.

Carneiro JS, Bento AS, Bacic D, Nearing BD, Rajamani S, Belardinelli L, Verrier RL.

J Cardiovasc Electrophysiol. 2015 Dec;26(12):1364-9. doi: 10.1111/jce.12824. Epub 2015 Oct 30.

PMID:
26331943
21.

Selective late INa inhibition by GS-458967 exerts parallel suppression of catecholamine-induced hemodynamically significant ventricular tachycardia and T-wave alternans in an intact porcine model.

Alves Bento AS, Bacic D, Saran Carneiro J, Nearing BD, Fuller H, Justo FA, Rajamani S, Belardinelli L, Verrier RL.

Heart Rhythm. 2015 Dec;12(12):2508-14. doi: 10.1016/j.hrthm.2015.07.025. Epub 2015 Jul 17.

PMID:
26190314
22.

Vagus nerve stimulation reduces cardiac electrical instability assessed by quantitative T-wave alternans analysis in patients with drug-resistant focal epilepsy.

Schomer AC, Nearing BD, Schachter SC, Verrier RL.

Epilepsia. 2014 Dec;55(12):1996-2002. doi: 10.1111/epi.12855. Epub 2014 Dec 3.

23.

Combined actions of ivabradine and ranolazine reduce ventricular rate during atrial fibrillation.

Verrier RL, Silva AF, Bonatti R, Batatinha JA, Nearing BD, Liu G, Rajamani S, Zeng D, Belardinelli L.

J Cardiovasc Electrophysiol. 2015 Mar;26(3):329-35. doi: 10.1111/jce.12569. Epub 2014 Dec 5.

PMID:
25346368
24.

Multilead template-derived residua of surface ECGS for quantitative assessment of arrhythmia risk.

Nearing BD, Verrier RL.

Ann Noninvasive Electrocardiol. 2015 May;20(3):273-81. doi: 10.1111/anec.12205. Epub 2014 Sep 18.

PMID:
25236344
25.

If inhibition in the atrioventricular node by ivabradine causes rate-dependent slowing of conduction and reduces ventricular rate during atrial fibrillation.

Verrier RL, Bonatti R, Silva AF, Batatinha JA, Nearing BD, Liu G, Rajamani S, Zeng D, Belardinelli L.

Heart Rhythm. 2014 Dec;11(12):2288-96. doi: 10.1016/j.hrthm.2014.08.007. Epub 2014 Aug 8.

PMID:
25111327
26.

Effects of exercise rehabilitation on cardiac electrical instability assessed by T-wave alternans during ambulatory electrocardiogram monitoring in coronary artery disease patients without and with diabetes mellitus.

Kenttä T, Tulppo MP, Nearing BD, Karjalainen JJ, Hautala AJ, Kiviniemi AM, Huikuri HV, Verrier RL.

Am J Cardiol. 2014 Sep 15;114(6):832-7. doi: 10.1016/j.amjcard.2014.06.014. Epub 2014 Jul 2.

PMID:
25107578
27.

Selective late sodium current blockade with GS-458967 markedly reduces ischemia-induced atrial and ventricular repolarization alternans and ECG heterogeneity.

Bonatti R, Silva AF, Batatinha JA, Sobrado LF, Machado AD, Varone BB, Nearing BD, Belardinelli L, Verrier RL.

Heart Rhythm. 2014 Oct;11(10):1827-35. doi: 10.1016/j.hrthm.2014.06.017. Epub 2014 Jun 17.

PMID:
24953379
28.

Relation of T-wave alternans to mortality and nonsustained ventricular tachycardia in patients with non-ST-segment elevation acute coronary syndrome from the MERLIN-TIMI 36 trial of ranolazine versus placebo.

Nieminen T, Scirica BM, Pegler JR, Tavares C, Pagotto VP, Kanas AF, Sobrado MF, Nearing BD, Umez-Eronini AA, Morrow DA, Belardinelli L, Verrier RL.

Am J Cardiol. 2014 Jul 1;114(1):17-23. doi: 10.1016/j.amjcard.2014.03.056. Epub 2014 Apr 16.

PMID:
24852915
29.

Screening entire health system ECG databases to identify patients at increased risk of death.

Strauss DG, Mewton N, Verrier RL, Nearing BD, Marchlinski FE, Killian T, Moxley J, Tereshchenko LG, Wu KC, Winslow R, Cox C, Spooner PM, Lima JA.

Circ Arrhythm Electrophysiol. 2013 Dec;6(6):1156-62. doi: 10.1161/CIRCEP.113.000411. Epub 2013 Oct 12.

30.

Inhibition of I(f) in the atrioventricular node as a mechanism for dronedarone's reduction in ventricular rate during atrial fibrillation.

Verrier RL, Sobrado MF, Pagotto VP, Kanas AF, Machado AD, Varone BB, Sobrado LF, Nearing BD, Zeng D, Belardinelli L.

Heart Rhythm. 2013 Nov;10(11):1692-7. doi: 10.1016/j.hrthm.2013.08.007. Epub 2013 Aug 9.

PMID:
23933296
31.

Dronedarone's inhibition of If current is the primary mechanism responsible for its bradycardic effect.

Sobrado LF, Varone BB, Machado AD, Nearing BD, Zeng D, Belardinelli L, Verrier RL.

J Cardiovasc Electrophysiol. 2013 Aug;24(8):914-8. doi: 10.1111/jce.12155. Epub 2013 May 3.

PMID:
23647933
32.

Elevated T-wave alternans predicts nonsustained ventricular tachycardia in association with percutaneous coronary intervention in ST-segment elevation myocardial infarction (STEMI) patients.

Verrier RL, Nearing BD, Ghanem RN, Olson RE, Garberich RF, Katsiyiannis WT, Gornick CC, Tang CY, Henry TD.

J Cardiovasc Electrophysiol. 2013 Jun;24(6):658-63. doi: 10.1111/jce.12102. Epub 2013 Feb 27.

PMID:
23445517
33.

HCN2/SkM1 gene transfer into canine left bundle branch induces stable, autonomically responsive biological pacing at physiological heart rates.

Boink GJ, Duan L, Nearing BD, Shlapakova IN, Sosunov EA, Anyukhovsky EP, Bobkov E, Kryukova Y, Ozgen N, Danilo P Jr, Cohen IS, Verrier RL, Robinson RB, Rosen MR.

J Am Coll Cardiol. 2013 Mar 19;61(11):1192-201. doi: 10.1016/j.jacc.2012.12.031. Epub 2013 Feb 6.

34.

Low doses of ranolazine and dronedarone in combination exert potent protection against atrial fibrillation and vulnerability to ventricular arrhythmias during acute myocardial ischemia.

Verrier RL, Pagotto VP, Kanas AF, Sobrado MF, Nearing BD, Zeng D, Belardinelli L.

Heart Rhythm. 2013 Jan;10(1):121-7. doi: 10.1016/j.hrthm.2012.09.015. Epub 2012 Sep 14.

PMID:
22985658
35.

Ca(2+)-stimulated adenylyl cyclase AC1 generates efficient biological pacing as single gene therapy and in combination with HCN2.

Boink GJ, Nearing BD, Shlapakova IN, Duan L, Kryukova Y, Bobkov Y, Tan HL, Cohen IS, Danilo P Jr, Robinson RB, Verrier RL, Rosen MR.

Circulation. 2012 Jul 31;126(5):528-36. doi: 10.1161/CIRCULATIONAHA.111.083584. Epub 2012 Jun 29.

36.

Crescendo in depolarization and repolarization heterogeneity heralds development of ventricular tachycardia in hospitalized patients with decompensated heart failure.

Nearing BD, Wellenius GA, Mittleman MA, Josephson ME, Burger AJ, Verrier RL.

Circ Arrhythm Electrophysiol. 2012 Feb;5(1):84-90. doi: 10.1161/CIRCEP.111.965434. Epub 2011 Dec 8.

37.

Antifibrillatory effect of ranolazine during severe coronary stenosis in the intact porcine model.

Nieminen T, Nanbu DY, Datti IP, Vaz GR, Tavares CA, Pegler JR, Nearing BD, Belardinelli L, Verrier RL.

Heart Rhythm. 2011 Apr;8(4):608-14. doi: 10.1016/j.hrthm.2010.11.029. Epub 2010 Nov 19.

PMID:
21094698
38.

Biological pacemakers in canines exhibit positive chronotropic response to emotional arousal.

Shlapakova IN, Nearing BD, Lau DH, Boink GJ, Danilo P Jr, Kryukova Y, Robinson RB, Cohen IS, Rosen MR, Verrier RL.

Heart Rhythm. 2010 Dec;7(12):1835-40. doi: 10.1016/j.hrthm.2010.08.004. Epub 2010 Aug 11.

PMID:
20708103
39.

Intrapericardial ranolazine prolongs atrial refractory period and markedly reduces atrial fibrillation inducibility in the intact porcine heart.

Carvas M, Nascimento BC, Acar M, Nearing BD, Belardinelli L, Verrier RL.

J Cardiovasc Pharmacol. 2010 Mar;55(3):286-91. doi: 10.1097/FJC.0b013e3181d26416.

PMID:
20075744
40.

T-wave alternans, air pollution and traffic in high-risk subjects.

Zanobetti A, Stone PH, Speizer FE, Schwartz JD, Coull BA, Suh HH, Nearing BD, Mittleman MA, Verrier RL, Gold DR.

Am J Cardiol. 2009 Sep 1;104(5):665-70. doi: 10.1016/j.amjcard.2009.04.046. Epub 2009 Jun 24.

41.

Re: Time-domain T-wave alternans measured from Holter electrocardiograms predicts cardiac mortality in patients with left ventricular dysfunction: a prospective study.

Verrier RL, Kumar K, Nearing BD.

Heart Rhythm. 2009 Apr;6(4):e1; author reply e1. doi: 10.1016/j.hrthm.2009.01.033. Epub 2009 Jan 31. No abstract available.

PMID:
19324300
42.

Ranolazine exerts potent effects on atrial electrical properties and abbreviates atrial fibrillation duration in the intact porcine heart.

Kumar K, Nearing BD, Carvas M, Nascimento BC, Acar M, Belardinelli L, Verrier RL.

J Cardiovasc Electrophysiol. 2009 Jul;20(7):796-802. doi: 10.1111/j.1540-8167.2009.01437.x. Epub 2009 Feb 27.

PMID:
19298570
43.

Basis for sudden cardiac death prediction by T-wave alternans from an integrative physiology perspective.

Verrier RL, Kumar K, Nearing BD.

Heart Rhythm. 2009 Mar;6(3):416-22. doi: 10.1016/j.hrthm.2008.11.019. Epub 2008 Nov 27. Review.

44.

Computer-aided visualization of microvolt T-wave alternans: "seeing is believing".

Verrier RL, Nearing BD, Kumar K.

J Cardiovasc Electrophysiol. 2008 Sep;19(9):E51-2. doi: 10.1111/j.1540-8167.2008.01261.x. Epub 2008 Jul 25. No abstract available.

PMID:
18662178
45.

Effect of ranolazine on ventricular vulnerability and defibrillation threshold in the intact porcine heart.

Kumar K, Nearing BD, Bartoli CR, Kwaku KF, Belardinelli L, Verrier RL.

J Cardiovasc Electrophysiol. 2008 Oct;19(10):1073-9. doi: 10.1111/j.1540-8167.2008.01204.x. Epub 2008 May 9.

PMID:
18479333
46.

Personal coronary risk profiles modify autonomic nervous system responses to air pollution.

Chen JC, Stone PH, Verrier RL, Nearing BD, MacCallum G, Kim JY, Herrick RF, You J, Zhou H, Christiani DC.

J Occup Environ Med. 2006 Nov;48(11):1133-42.

PMID:
17099449
47.

Suppression of calcium-induced repolarization heterogeneity as a mechanism of nitroglycerin's antiarrhythmic action.

Zhao SX, Lee LM, Nearing BD, Busso VO, Kwaku KF, Verrier RL.

J Cardiovasc Pharmacol. 2006 Aug;48(2):22-9.

PMID:
16954817
48.

Air pollution and ST-segment depression in elderly subjects.

Gold DR, Litonjua AA, Zanobetti A, Coull BA, Schwartz J, MacCallum G, Verrier RL, Nearing BD, Canner MJ, Suh H, Stone PH.

Environ Health Perspect. 2005 Jul;113(7):883-7.

49.

T-wave alternans: does size matter.

Verrier RL, Kwaku KF, Nearing BD, Josephson ME.

J Cardiovasc Electrophysiol. 2005 Jun;16(6):625-8. No abstract available.

PMID:
15946362
50.

Traffic related pollution and heart rate variability in a panel of elderly subjects.

Schwartz J, Litonjua A, Suh H, Verrier M, Zanobetti A, Syring M, Nearing B, Verrier R, Stone P, MacCallum G, Speizer FE, Gold DR.

Thorax. 2005 Jun;60(6):455-61.

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