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Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Chowdhury AH, Adiamah A, Kushairi A, Varadhan KK, Krznaric Z, Kulkarni AD, Neal KR, Lobo DN.

Ann Surg. 2019 Aug 28. doi: 10.1097/SLA.0000000000003581. [Epub ahead of print]


Antibiotics Versus Appendicectomy for the Treatment of Uncomplicated Acute Appendicitis: An Updated Meta-Analysis of Randomised Controlled Trials.

Rollins KE, Varadhan KK, Neal KR, Lobo DN.

World J Surg. 2016 Oct;40(10):2305-18. doi: 10.1007/s00268-016-3561-7.


Hydration and outcome in older patients admitted to hospital (The HOOP prospective cohort study).

El-Sharkawy AM, Watson P, Neal KR, Ljungqvist O, Maughan RJ, Sahota O, Lobo DN.

Age Ageing. 2015 Nov;44(6):943-7. doi: 10.1093/ageing/afv119. Epub 2015 Aug 26.


Effect of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial.

Read RC, Baxter D, Chadwick DR, Faust SN, Finn A, Gordon SB, Heath PT, Lewis DJ, Pollard AJ, Turner DP, Bazaz R, Ganguli A, Havelock T, Neal KR, Okike IO, Morales-Aza B, Patel K, Snape MD, Williams J, Gilchrist S, Gray SJ, Maiden MC, Toneatto D, Wang H, McCarthy M, Dull PM, Borrow R.

Lancet. 2014 Dec 13;384(9960):2123-31. doi: 10.1016/S0140-6736(14)60842-4. Epub 2014 Aug 18.


Phase variation mediates reductions in expression of surface proteins during persistent meningococcal carriage.

Alamro M, Bidmos FA, Chan H, Oldfield NJ, Newton E, Bai X, Aidley J, Care R, Mattick C, Turner DP, Neal KR, Ala'aldeen DA, Feavers I, Borrow R, Bayliss CD.

Infect Immun. 2014 Jun;82(6):2472-84. doi: 10.1128/IAI.01521-14. Epub 2014 Mar 31.


The cost of treatment failure: resource use and costs incurred by hepatitis C virus genotype 1-infected patients who do or do not achieve sustained virological response to therapy.

Backx M, Lewszuk A, White JR, Cole J, Sreedharan A, van Sanden S, Diels J, Lawson A, Neal KR, Wiselka MJ, Ito T, Irving WL.

J Viral Hepat. 2014 Mar;21(3):208-15. doi: 10.1111/jvh.12132. Epub 2013 Aug 1.


An epidemiological review of changes in meningococcal biology during the last 100 years.

Abio A, Neal KR, Beck CR.

Pathog Glob Health. 2013 Oct;107(7):373-80. Epub 2013 Dec 19. Review.


Bed occupancy rates and hospital-acquired Clostridium difficile infection: a cohort study.

Ahyow LC, Lambert PC, Jenkins DR, Neal KR, Tobin M.

Infect Control Hosp Epidemiol. 2013 Oct;34(10):1062-9. doi: 10.1086/673156. Epub 2013 Aug 23.


Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis.

Oldfield NJ, Matar S, Bidmos FA, Alamro M, Neal KR, Turner DP, Bayliss CD, Ala'aldeen DA.

PLoS One. 2013 Jul 25;8(7):e69746. doi: 10.1371/journal.pone.0069746. Print 2013.


Identifying and testing candidate genetic polymorphisms in the irritable bowel syndrome (IBS): association with TNFSF15 and TNFα.

Swan C, Duroudier NP, Campbell E, Zaitoun A, Hastings M, Dukes GE, Cox J, Kelly FM, Wilde J, Lennon MG, Neal KR, Whorwell PJ, Hall IP, Spiller RC.

Gut. 2013 Jul;62(7):985-94. doi: 10.1136/gutjnl-2011-301213. Epub 2012 Jun 8.


Molecular epidemiology of human Campylobacter jejuni shows association between seasonal and international patterns of disease.

McCarthy ND, Gillespie IA, Lawson AJ, Richardson J, Neal KR, Hawtin PR, Maiden MC, O'Brien SJ.

Epidemiol Infect. 2012 Dec;140(12):2247-55. doi: 10.1017/S0950268812000192. Epub 2012 Feb 28.


Carriage of meningococci by university students, United Kingdom.

Ala'aldeen DA, Oldfield NJ, Bidmos FA, Abouseada NM, Ahmed NW, Turner DP, Neal KR, Bayliss CD.

Emerg Infect Dis. 2011 Sep;17(9):1762-3. doi: 10.3201/eid1709.101762. No abstract available.


Changes in serogroup and genotype prevalence among carried meningococci in the United Kingdom during vaccine implementation.

Ibarz-Pavón AB, Maclennan J, Andrews NJ, Gray SJ, Urwin R, Clarke SC, Walker AM, Evans MR, Kroll JS, Neal KR, Ala'aldeen D, Crook DW, Cann K, Harrison S, Cunningham R, Baxter D, Kaczmarski E, McCarthy ND, Jolley KA, Cameron JC, Stuart JM, Maiden MC.

J Infect Dis. 2011 Oct 1;204(7):1046-53. doi: 10.1093/infdis/jir466.


Prevalence and risk factors for hepatitis C virus infection in Kech District, Balochistan, Pakistan: most infections remain unexplained. A cross-sectional study.

Ahmed F, Irving WL, Anwar M, Myles P, Neal KR.

Epidemiol Infect. 2012 Apr;140(4):716-23. doi: 10.1017/S0950268811001087. Epub 2011 Jun 15.


Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence.

Tauseef I, Harrison OB, Wooldridge KG, Feavers IM, Neal KR, Gray SJ, Kriz P, Turner DPJ, Ala'Aldeen DAA, Maiden MCJ, Bayliss CD.

Microbiology. 2011 May;157(Pt 5):1446-1456. doi: 10.1099/mic.0.046946-0. Epub 2011 Feb 10.


Persistence, replacement, and rapid clonal expansion of meningococcal carriage isolates in a 2008 university student cohort.

Bidmos FA, Neal KR, Oldfield NJ, Turner DP, Ala'Aldeen DA, Bayliss CD.

J Clin Microbiol. 2011 Feb;49(2):506-12. doi: 10.1128/JCM.01322-10. Epub 2010 Dec 1.


Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage.

Ala'aldeen DA, Flint M, Oldfield NJ, Omer SA, McNeil LK, Jiang Q, Murphy E, Giardina PC, Novikova EG, Dodge-Scully IL, Bayliss CD, Turner DP, Neal KR, Hoiseth SK, Jansen KU, Anderson AS.

Vaccine. 2010 Nov 10;28(48):7667-75. doi: 10.1016/j.vaccine.2010.09.038. Epub 2010 Sep 25.


The Patient Health Questionnaire 12 Somatic Symptom scale as a predictor of symptom severity and consulting behaviour in patients with irritable bowel syndrome and symptomatic diverticular disease.

Spiller RC, Humes DJ, Campbell E, Hastings M, Neal KR, Dukes GE, Whorwell PJ.

Aliment Pharmacol Ther. 2010 Sep;32(6):811-20. doi: 10.1111/j.1365-2036.2010.04402.x.


Methods for determining disease burden and calibrating national surveillance data in the United Kingdom: the second study of infectious intestinal disease in the community (IID2 study).

O'Brien SJ, Rait G, Hunter PR, Gray JJ, Bolton FJ, Tompkins DS, McLauchlin J, Letley LH, Adak GK, Cowden JM, Evans MR, Neal KR, Smith GE, Smyth B, Tam CC, Rodrigues LC.

BMC Med Res Methodol. 2010 May 5;10:39. doi: 10.1186/1471-2288-10-39.


The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials.

Varadhan KK, Neal KR, Dejong CH, Fearon KC, Ljungqvist O, Lobo DN.

Clin Nutr. 2010 Aug;29(4):434-40. doi: 10.1016/j.clnu.2010.01.004. Epub 2010 Jan 29.


Antibiotic therapy versus appendectomy for acute appendicitis: a meta-analysis.

Varadhan KK, Humes DJ, Neal KR, Lobo DN.

World J Surg. 2010 Feb;34(2):199-209. doi: 10.1007/s00268-009-0343-5.


Chicken consumption and use of acid-suppressing medications as risk factors for Campylobacter enteritis, England.

Tam CC, Higgins CD, Neal KR, Rodrigues LC, Millership SE, O'Brien SJ; Campylobacter Case-Control Study Group.

Emerg Infect Dis. 2009 Sep;15(9):1402-8. doi: 10.3201/eid1509.080773.


Autoantibodies in chronic hepatitis C virus infection and their association with disease profile.

Williams MJ, Lawson A, Neal KR, Ryder SD, Irving WL; Trent HCV Group.

J Viral Hepat. 2009 May;16(5):325-31. doi: 10.1111/j.1365-2893.2008.01035.x. Epub 2009 Mar 3.


Impact of meningococcal serogroup C conjugate vaccines on carriage and herd immunity.

Maiden MC, Ibarz-Pavón AB, Urwin R, Gray SJ, Andrews NJ, Clarke SC, Walker AM, Evans MR, Kroll JS, Neal KR, Ala'aldeen DA, Crook DW, Cann K, Harrison S, Cunningham R, Baxter D, Kaczmarski E, Maclennan J, Cameron JC, Stuart JM.

J Infect Dis. 2008 Mar 1;197(5):737-43. doi: 10.1086/527401.


Psychological and colonic factors in painful diverticulosis.

Humes DJ, Simpson J, Neal KR, Scholefield JH, Spiller RC.

Br J Surg. 2008 Feb;95(2):195-8.


The pathological response to neoadjuvant chemotherapy with FOLFOX-4 for colorectal liver metastases: a comparative study.

Aloysius MM, Zaitoun AM, Beckingham IJ, Neal KR, Aithal GP, Bessell EM, Lobo DN.

Virchows Arch. 2007 Nov;451(5):943-8. Epub 2007 Sep 6.


The natural history of hepatitis C with severe hepatic fibrosis.

Lawson A, Hagan S, Rye K, Taguri N, Ratib S, Zaitoun AM, Neal KR, Ryder SD, Irving WL; Trent HCV Study Group.

J Hepatol. 2007 Jul;47(1):37-45. Epub 2007 Mar 7.


Excess mortality rates in a cohort of patients infected with the hepatitis C virus: a prospective study.

Neal KR; Trent Hepatitis C Study Group, Ramsay S, Thomson BJ, Irving WL.

Gut. 2007 Aug;56(8):1098-104. Epub 2007 Mar 7.


Early postoperative jejunostomy feeding with an immune modulating diet in patients undergoing resectional surgery for upper gastrointestinal cancer: a prospective, randomized, controlled, double-blind study.

Lobo DN, Williams RN, Welch NT, Aloysius MM, Nunes QM, Padmanabhan J, Crowe JR, Iftikhar SY, Parsons SL, Neal KR, Allison SP, Rowlands BJ.

Clin Nutr. 2006 Oct;25(5):716-26. Epub 2006 Jun 13.


Investigating vomiting and/or bloody diarrhoea in Campylobacter jejuni infection.

Gillespie IA, O'Brien SJ, Frost JA, Tam C, Tompkins D, Neal KR, Syed Q, Farthing MJG, The Campylobacter Sentinel Surveillance Scheme Collaborators.

J Med Microbiol. 2006 Jun;55(Pt 6):741-746. doi: 10.1099/jmm.0.46422-0.


Clinical pathways for patients with newly diagnosed hepatitis C - what actually happens.

Irving WL, Smith S, Cater R, Pugh S, Neal KR, Coupland CA, Ryder SD, Thomson BJ, Pringle M, Bicknell M, Hippisley-Cox J.

J Viral Hepat. 2006 Apr;13(4):264-71.


Estimated progression rates in three United Kingdom hepatitis C cohorts differed according to method of recruitment.

Sweeting MJ, De Angelis D, Neal KR, Ramsay ME, Irving WL, Wright M, Brant L, Harris HE; Trent HCV Study Group; HCV National Register Steering Group.

J Clin Epidemiol. 2006 Feb;59(2):144-52.


Cervical human papillomavirus screening among older women.

Grainge MJ, Seth R, Guo L, Neal KR, Coupland C, Vryenhoef P, Johnson J, Jenkins D.

Emerg Infect Dis. 2005 Nov;11(11):1680-5.


Relationships between structural and functional measures of nutritional status in a normally nourished population.

Hornby ST, Nunes QM, Hillman TE, Stanga Z, Neal KR, Rowlands BJ, Allison SP, Lobo DN.

Clin Nutr. 2005 Jun;24(3):421-6.


Human papillomavirus infection in women who develop high-grade cervical intraepithelial neoplasia or cervical cancer: a case-control study in the UK.

Grainge MJ, Seth R, Coupland C, Guo L, Rittman T, Vryenhoef P, Johnson J, Jenkins D, Neal KR.

Br J Cancer. 2005 May 9;92(9):1794-9.


A practical posture for hand grip dynamometry in the clinical setting.

Hillman TE, Nunes QM, Hornby ST, Stanga Z, Neal KR, Rowlands BJ, Allison SP, Lobo DN.

Clin Nutr. 2005 Apr;24(2):224-8.


Is Campylobacter jejuni enteritis a weekend disease?

Gillespie IA, O'Brien SJ, Neal KR, Frost JA, Cowden JM, Syed Q; Campylobacter Sentinel Surveillance Scheme Collaborators.

J Infect. 2005 Apr;50(3):265-7. No abstract available.


Stapled hemorrhoidopexy compared with conventional hemorrhoidectomy: systematic review of randomized, controlled trials.

Nisar PJ, Acheson AG, Neal KR, Scholefield JH.

Dis Colon Rectum. 2004 Nov;47(11):1837-45. Review.


Progression of hepatic fibrosis in patients with hepatitis C: a prospective repeat liver biopsy study.

Ryder SD, Irving WL, Jones DA, Neal KR, Underwood JC; Trent Hepatitis C Study Group.

Gut. 2004 Mar;53(3):451-5.


Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS.

Dunlop SP, Jenkins D, Neal KR, Spiller RC.

Gastroenterology. 2003 Dec;125(6):1651-9.


Patterns of pain in diverticular disease and the influence of acute diverticulitis.

Simpson J, Neal KR, Scholefield JH, Spiller RC.

Eur J Gastroenterol Hepatol. 2003 Sep;15(9):1005-10.


Randomized, double-blind, placebo-controlled trial of prednisolone in post-infectious irritable bowel syndrome.

Dunlop SP, Jenkins D, Neal KR, Naesdal J, Borgaonker M, Collins SM, Spiller RC.

Aliment Pharmacol Ther. 2003 Jul 1;18(1):77-84.


Independent subsets of amplified fragments from the genome of Neisseria meningitidis identify the same invasive clones of ET37 and ET5.

Goulding JN, Stanley J, Olver W, Neal KR, Ala'Aldeen DAA, Arnold C.

J Med Microbiol. 2003 Feb;52(Pt 2):151-154. doi: 10.1099/jmm.0.05012-0.


A case-case comparison of Campylobacter coli and Campylobacter jejuni infection: a tool for generating hypotheses.

Gillespie IA, O'Brien SJ, Frost JA, Adak GK, Horby P, Swan AV, Painter MJ, Neal KR; Campylobacter Sentinel Surveillance Scheme Collaborators.

Emerg Infect Dis. 2002 Sep;8(9):937-42.


Peri-operative fluid and electrolyte management: a survey of consultant surgeons in the UK.

Lobo DN, Dube MG, Neal KR, Allison SP, Rowlands BJ.

Ann R Coll Surg Engl. 2002 May;84(3):156-60.


Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial.

Lobo DN, Bostock KA, Neal KR, Perkins AC, Rowlands BJ, Allison SP.

Lancet. 2002 May 25;359(9320):1812-8.


Characterization of humoral and cellular immune responses elicited by meningococcal carriage.

Robinson K, Neal KR, Howard C, Stockton J, Atkinson K, Scarth E, Moran J, Robins A, Todd I, Kaczmarski E, Gray S, Muscat I, Slack R, Ala'Aldeen DA.

Infect Immun. 2002 Mar;70(3):1301-9.

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